IL133315A0 - Ntn-2 member of tnf ligand family - Google Patents
Ntn-2 member of tnf ligand familyInfo
- Publication number
- IL133315A0 IL133315A0 IL13331598A IL13331598A IL133315A0 IL 133315 A0 IL133315 A0 IL 133315A0 IL 13331598 A IL13331598 A IL 13331598A IL 13331598 A IL13331598 A IL 13331598A IL 133315 A0 IL133315 A0 IL 133315A0
- Authority
- IL
- Israel
- Prior art keywords
- ntn
- tnf ligand
- ligand family
- family
- tnf
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4877697P | 1997-06-06 | 1997-06-06 | |
US6638697P | 1997-11-21 | 1997-11-21 | |
PCT/US1998/011153 WO1998055620A1 (en) | 1997-06-06 | 1998-06-03 | Ntn-2 member of tnf ligand family |
Publications (1)
Publication Number | Publication Date |
---|---|
IL133315A0 true IL133315A0 (en) | 2001-04-30 |
Family
ID=26726520
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13331598A IL133315A0 (en) | 1997-06-06 | 1998-06-03 | Ntn-2 member of tnf ligand family |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1012292A1 (de) |
JP (1) | JP2002504818A (de) |
AU (1) | AU743490B2 (de) |
IL (1) | IL133315A0 (de) |
WO (1) | WO1998055620A1 (de) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6812327B1 (en) | 1996-10-25 | 2004-11-02 | Human Genome Sciences, Inc. | Neutrokine-alpha polypeptides |
US6689579B1 (en) | 1996-10-25 | 2004-02-10 | Human Genome Sciences, Inc. | Polynucleotides encoding neutrokine-α |
WO1999011791A2 (en) * | 1997-09-05 | 1999-03-11 | University Of Washington | Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents |
WO1999026463A2 (en) * | 1997-11-26 | 1999-06-03 | Eli Lilly And Company | Tnf ligand family gene |
US6297367B1 (en) | 1997-12-30 | 2001-10-02 | Chiron Corporation | Polynucleotide encoding TNFL1 |
AU2093499A (en) * | 1997-12-30 | 1999-07-19 | Chiron Corporation | Members of tnf and tnfr families |
US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
US7488590B2 (en) | 1998-10-23 | 2009-02-10 | Amgen Inc. | Modified peptides as therapeutic agents |
ES2388341T3 (es) | 1998-10-23 | 2012-10-11 | Kirin-Amgen Inc. | Péptidos miméticos de trombopoyetina diméricos que se unen al receptor MPL y que tienen actividad trombopoyética |
AU1467000A (en) * | 1998-11-04 | 2000-05-22 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | A novel tumor necrosis factor family member, drl, and related compositions and methods |
GB9828628D0 (en) * | 1998-12-23 | 1999-02-17 | Glaxo Group Ltd | Novel ligand |
PL393286A1 (pl) * | 1999-01-07 | 2011-06-06 | Zymogenetics, Inc. | Rozpuszczalny receptor BR43x2 i sposoby jego zastosowania |
US7833529B1 (en) | 1999-01-07 | 2010-11-16 | Zymogenetics, Inc. | Methods for inhibiting B lymphocyte proliferation with soluble ztnf4 receptor |
EP1415659B9 (de) | 1999-01-25 | 2012-02-15 | Biogen Idec MA Inc. | Verwendung eines Antikörpers gegen wasserlöslich BAFF zur Krebsbehandlung |
US20030095967A1 (en) | 1999-01-25 | 2003-05-22 | Mackay Fabienne | BAFF, inhibitors thereof and their use in the modulation of B-cell response and treatment of autoimmune disorders |
US20030022233A1 (en) | 1999-04-30 | 2003-01-30 | Raymond G. Goodwin | Methods of use of the taci/taci-l interaction |
KR20090016772A (ko) | 1999-08-17 | 2009-02-17 | 바이오겐 아이덱 엠에이 인코포레이티드 | Baff 수용체(bcma), 면역조절제 |
UA74798C2 (uk) | 1999-10-06 | 2006-02-15 | Байоджен Айдек Ма Інк. | Спосіб лікування раку у ссавця за допомогою поліпептиду, що протидіє взаємодії april з його рецепторами |
AU2001241418A1 (en) * | 2000-01-31 | 2001-08-07 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
AU2001259432B2 (en) * | 2000-05-03 | 2005-04-21 | Amgen Inc. | Modified peptides, comprising an FC domain, as therapeutic agents |
EP1280826B1 (de) | 2000-05-12 | 2007-05-02 | Amgen Inc. | Polypeptiden, die die april-vermittelte aktivierung von t-und b-zellen hemmen |
US7220840B2 (en) | 2000-06-16 | 2007-05-22 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to B lymphocyte stimulator protein |
ATE494304T1 (de) | 2000-06-16 | 2011-01-15 | Human Genome Sciences Inc | Immunspezifisch bindende antikörper gegen blys |
WO2002016411A2 (en) | 2000-08-18 | 2002-02-28 | Human Genome Sciences, Inc. | Binding polypeptides and methods based thereon |
UA83458C2 (uk) | 2000-09-18 | 2008-07-25 | Байоджен Айдек Ма Інк. | Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf) |
SI1385882T1 (sl) | 2001-05-11 | 2008-04-30 | Amgen Inc | Peptidi in sorodne molekule, ki se vežejo na tall-1 |
EA007275B1 (ru) | 2001-05-24 | 2006-08-25 | Займодженетикс, Инк. | Слитые белки taci-иммуноглобулина |
JP5524441B2 (ja) | 2003-03-28 | 2014-06-18 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 短縮されたbaffレセプター |
EP2332563A3 (de) | 2004-10-13 | 2013-03-13 | The Washington University | Verwendung von BAFF zur Behandlung von Sepsis |
WO2007019573A2 (en) | 2005-08-09 | 2007-02-15 | Zymogenetics, Inc. | Methods for the treatment and prevention of abnormal cell proliferation using taci-fusion molecules |
KR20080056714A (ko) | 2005-08-09 | 2008-06-23 | 지모제넥틱스, 인코포레이티드 | TACI―Ig 융합 분자를 사용하여 B―세포 악성종양을치료하는 방법 |
US8008453B2 (en) | 2005-08-12 | 2011-08-30 | Amgen Inc. | Modified Fc molecules |
US9168286B2 (en) | 2005-10-13 | 2015-10-27 | Human Genome Sciences, Inc. | Methods and compositions for use in treatment of patients with autoantibody positive disease |
US9726673B2 (en) | 2005-11-23 | 2017-08-08 | Genentech, Inc. | Methods and compositions related to B cell assays |
WO2007123765A2 (en) | 2006-03-31 | 2007-11-01 | Human Genome Sciences Inc. | Neutrokine-alpha and neutrokine-alpha splice variant |
BRPI0711823A2 (pt) | 2006-05-15 | 2012-01-17 | Ares Trading Sa | métodos para tratamento de doenças auto-imunes com uma molécula de fusão taci-ig |
JOP20140087B1 (ar) | 2013-03-13 | 2021-08-17 | Amgen Inc | بروتينات مخصصة ل baff و b7rp1 وإستخداماتها |
US9458246B2 (en) | 2013-03-13 | 2016-10-04 | Amgen Inc. | Proteins specific for BAFF and B7RP1 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE302272T1 (de) * | 1996-10-25 | 2005-09-15 | Human Genome Sciences Inc | Neutrokin alpha |
AU5705898A (en) * | 1996-12-17 | 1998-07-15 | Schering Corporation | Mammalian cell surface antigens; related reagents |
-
1998
- 1998-06-03 EP EP98925109A patent/EP1012292A1/de not_active Withdrawn
- 1998-06-03 IL IL13331598A patent/IL133315A0/xx unknown
- 1998-06-03 AU AU77130/98A patent/AU743490B2/en not_active Ceased
- 1998-06-03 JP JP50267899A patent/JP2002504818A/ja active Pending
- 1998-06-03 WO PCT/US1998/011153 patent/WO1998055620A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO1998055620A1 (en) | 1998-12-10 |
JP2002504818A (ja) | 2002-02-12 |
AU7713098A (en) | 1998-12-21 |
EP1012292A1 (de) | 2000-06-28 |
AU743490B2 (en) | 2002-01-24 |
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