IL132105A0 - Caspase-8 interacting proteins - Google Patents

Caspase-8 interacting proteins

Info

Publication number
IL132105A0
IL132105A0 IL13210599A IL13210599A IL132105A0 IL 132105 A0 IL132105 A0 IL 132105A0 IL 13210599 A IL13210599 A IL 13210599A IL 13210599 A IL13210599 A IL 13210599A IL 132105 A0 IL132105 A0 IL 132105A0
Authority
IL
Israel
Prior art keywords
caspase
interacting proteins
interacting
proteins
Prior art date
Application number
IL13210599A
Other languages
English (en)
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL12772198A external-priority patent/IL127721A0/xx
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Priority to IL178921A priority Critical patent/IL178921A0/en
Priority to IL13210599A priority patent/IL132105A0/xx
Priority to AU17950/00A priority patent/AU780585B2/en
Priority to IL13802599A priority patent/IL138025A0/xx
Priority to NZ506477A priority patent/NZ506477A/en
Priority to PL99350181A priority patent/PL350181A1/xx
Priority to KR1020007009343A priority patent/KR100646074B1/ko
Priority to EA200000875A priority patent/EA005853B1/ru
Priority to EA200401390A priority patent/EA007273B1/ru
Priority to CNA2004100563830A priority patent/CN1603342A/zh
Priority to HU0100671A priority patent/HUP0100671A3/hu
Priority to BR9909252-2A priority patent/BR9909252A/pt
Priority to CA002321672A priority patent/CA2321672A1/en
Priority to EP99961257A priority patent/EP1058691A1/en
Priority to EEP200000487A priority patent/EE200000487A/xx
Priority to CNB998053627A priority patent/CN1223608C/zh
Priority to KR1020067015048A priority patent/KR100646075B1/ko
Priority to JP2000591071A priority patent/JP2002536965A/ja
Priority to ARP990106739A priority patent/AR029321A1/es
Priority to PCT/IL1999/000698 priority patent/WO2000039160A2/en
Priority to SK1268-2000A priority patent/SK12682000A3/sk
Priority to NO20004167A priority patent/NO20004167L/no
Priority to BG104707A priority patent/BG65375B1/bg
Priority to IL138025A priority patent/IL138025A/en
Priority to US09/644,827 priority patent/US6762283B1/en
Publication of IL132105A0 publication Critical patent/IL132105A0/xx
Priority to HK01107798A priority patent/HK1037197A1/xx
Priority to US10/814,160 priority patent/US7339047B2/en
Priority to BG109904A priority patent/BG109904A/bg
Priority to US11/970,986 priority patent/US20080139476A1/en

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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472Cysteine endopeptidases (3.4.22)
    • C12N9/6475Interleukin 1-beta convertase-like enzymes (3.4.22.10; 3.4.22.36; 3.4.22.63)
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y305/00Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01033N-Acetylglucosamine deacetylase (3.5.1.33)
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00Methods of screening libraries
    • C40B30/06Methods of screening libraries by measuring effects on living organisms, tissues or cells
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    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/06Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C40B40/08Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/11Antisense
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    • C12N2310/12Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering N.A.
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value

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  • Biotechnology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Diabetes (AREA)
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  • Gastroenterology & Hepatology (AREA)
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  • Heart & Thoracic Surgery (AREA)
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IL13210599A 1998-12-24 1999-09-28 Caspase-8 interacting proteins IL132105A0 (en)

Priority Applications (29)

Application Number Priority Date Filing Date Title
IL178921A IL178921A0 (en) 1998-12-24 1999-09-28 Caspase-8 interacting proteins
IL13210599A IL132105A0 (en) 1998-12-24 1999-09-28 Caspase-8 interacting proteins
SK1268-2000A SK12682000A3 (sk) 1998-12-24 1999-12-23 Proteíny interagujúce s kaspázou-8, izolovaná dna, vektor obsahujúci dna sekvenciu, eukaryotická a prokaryotická bunka, spôsob ich výroby a ich použitie
EEP200000487A EE200000487A (et) 1998-12-24 1999-12-23 Kaspaas-8 proteaasiga interakteeruv proteiin, seda kodeeriv DNA järjestus, selle valmistamis- ja identifitseerimismeetod ning kasutamine ravimi valmistamiseks
CNB998053627A CN1223608C (zh) 1998-12-24 1999-12-23 与半胱天冬蛋白酶-8相互作用的蛋白
NZ506477A NZ506477A (en) 1998-12-24 1999-12-23 Caspase-8 interacting proteins
PL99350181A PL350181A1 (en) 1998-12-24 1999-12-23 Caspase−8 interacting proteins
KR1020007009343A KR100646074B1 (ko) 1998-12-24 1999-12-23 카스파제-8 상호작용 단백질
EA200000875A EA005853B1 (ru) 1998-12-24 1999-12-23 N-ацетилглюкозамин-6-фосфатдеацетилаза человека, взаимодействующая с каспазой-8, и способы ее применения
EA200401390A EA007273B1 (ru) 1998-12-24 1999-12-23 Выделенный полипептид, связывающийся с каспазой -8, и способы его применения
CNA2004100563830A CN1603342A (zh) 1998-12-24 1999-12-23 与半胱天冬蛋白酶-8相互作用的蛋白
HU0100671A HUP0100671A3 (en) 1998-12-24 1999-12-23 Caspase-8 interacting proteins
BR9909252-2A BR9909252A (pt) 1998-12-24 1999-12-23 Proteìnas de interação caspase-8
CA002321672A CA2321672A1 (en) 1998-12-24 1999-12-23 Caspase-8 interacting proteins
EP99961257A EP1058691A1 (en) 1998-12-24 1999-12-23 Caspase-8 interacting proteins
AU17950/00A AU780585B2 (en) 1998-12-24 1999-12-23 Caspase-8 interacting proteins
IL13802599A IL138025A0 (en) 1998-12-24 1999-12-23 Caspase-8 interacting proteins
KR1020067015048A KR100646075B1 (ko) 1998-12-24 1999-12-23 카스파제-8 상호작용 단백질
JP2000591071A JP2002536965A (ja) 1998-12-24 1999-12-23 カスパーゼ−8相互作用タンパク質
ARP990106739A AR029321A1 (es) 1998-12-24 1999-12-23 Proteinas interactivas con la caspasa 8, isoformas, variantes alelicas, fragmentos analogos funcionales- mutantes y derivados de los mismos, aislados de dna que codifican dichas proteinas, vectorres, que incluyen dichas secuencias y celulas eucariotas que comprenden dichos vectores, metodo para prod
PCT/IL1999/000698 WO2000039160A2 (en) 1998-12-24 1999-12-23 Caspase-8 interacting proteins
NO20004167A NO20004167L (no) 1998-12-24 2000-08-21 Kaspase-8 interagerende proteiner
BG104707A BG65375B1 (bg) 1998-12-24 2000-08-22 Белтъци, взаимодействащи с каспаза-8
IL138025A IL138025A (en) 1998-12-24 2000-08-23 Proteins that interact with Caspase-8
US09/644,827 US6762283B1 (en) 1998-12-24 2000-08-24 Caspase-8 interacting proteins
HK01107798A HK1037197A1 (en) 1998-12-24 2001-11-07 Caspase-8 interacting proteins
US10/814,160 US7339047B2 (en) 1998-12-24 2004-04-01 Caspase-8 interacting proteins
BG109904A BG109904A (bg) 1998-12-24 2007-07-02 Белтъци, взаимодействащи с капсаза-8
US11/970,986 US20080139476A1 (en) 1998-12-24 2008-01-08 Caspase-8 interacting proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL12772198A IL127721A0 (en) 1998-12-24 1998-12-24 Caspase-8 interacting proteins
IL13210599A IL132105A0 (en) 1998-12-24 1999-09-28 Caspase-8 interacting proteins

Publications (1)

Publication Number Publication Date
IL132105A0 true IL132105A0 (en) 2001-03-19

Family

ID=26323761

Family Applications (3)

Application Number Title Priority Date Filing Date
IL13210599A IL132105A0 (en) 1998-12-24 1999-09-28 Caspase-8 interacting proteins
IL178921A IL178921A0 (en) 1998-12-24 1999-09-28 Caspase-8 interacting proteins
IL138025A IL138025A (en) 1998-12-24 2000-08-23 Proteins that interact with Caspase-8

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL178921A IL178921A0 (en) 1998-12-24 1999-09-28 Caspase-8 interacting proteins
IL138025A IL138025A (en) 1998-12-24 2000-08-23 Proteins that interact with Caspase-8

Country Status (20)

Country Link
US (3) US6762283B1 (ja)
EP (1) EP1058691A1 (ja)
JP (1) JP2002536965A (ja)
KR (2) KR100646074B1 (ja)
CN (2) CN1223608C (ja)
AR (1) AR029321A1 (ja)
AU (1) AU780585B2 (ja)
BG (2) BG65375B1 (ja)
BR (1) BR9909252A (ja)
CA (1) CA2321672A1 (ja)
EA (2) EA005853B1 (ja)
EE (1) EE200000487A (ja)
HK (1) HK1037197A1 (ja)
HU (1) HUP0100671A3 (ja)
IL (3) IL132105A0 (ja)
NO (1) NO20004167L (ja)
NZ (1) NZ506477A (ja)
PL (1) PL350181A1 (ja)
SK (1) SK12682000A3 (ja)
WO (1) WO2000039160A2 (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA04002103A (es) * 2001-09-04 2004-06-07 Yeda Res & Dev Una proteina de union a caspasa-8, su preparacion y uso.
US20040072770A1 (en) * 2002-07-03 2004-04-15 Besterman Jeffrey M. Methods for specifically inhibiting histone deacetylase-7 and 8
IL158599A0 (en) * 2003-10-26 2004-05-12 Yeda Res & Dev Methods of modulating hematopoiesis
JP5513130B2 (ja) * 2007-02-23 2014-06-04 イェダ リサーチ アンド デベロップメント カンパニー リミテッド 金属タンパク質の活性を阻害するために有用な抗体および該抗体を含有する医薬組成物
US8809002B2 (en) * 2008-07-10 2014-08-19 Dana-Farber Cancer Institute, Inc. MUC1, caspase-8, and DED-containing proteins
JP6710680B2 (ja) 2014-09-04 2020-06-17 メモリアル スローン ケタリング キャンサー センター ヘモグロビン異常症を処置するためのグロビン遺伝子療法
CN104694485A (zh) * 2015-02-13 2015-06-10 广西壮族自治区兽医研究所 Z-ietd-fmk在提高prrsv体外培养滴度方面的应用及其方法
CN106146665B (zh) * 2016-08-31 2019-08-09 中国农业科学院植物保护研究所 一种用于制备针对甜菜夜蛾caspase-5大亚基的抗体的方法
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