IL131005A0 - Il-8 receptor antagonists - Google Patents
Il-8 receptor antagonistsInfo
- Publication number
- IL131005A0 IL131005A0 IL13100598A IL13100598A IL131005A0 IL 131005 A0 IL131005 A0 IL 131005A0 IL 13100598 A IL13100598 A IL 13100598A IL 13100598 A IL13100598 A IL 13100598A IL 131005 A0 IL131005 A0 IL 131005A0
- Authority
- IL
- Israel
- Prior art keywords
- receptor antagonists
- antagonists
- receptor
- Prior art date
Links
- 102000010681 interleukin-8 receptors Human genes 0.000 title 1
- 108010038415 interleukin-8 receptors Proteins 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
- C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL15040598A IL150405A0 (en) | 1997-01-23 | 1998-01-23 | BENZOISOTHIAZOLE SUBSTITUTED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, PROCESS FOR THEIR PREPARATION AND USE THEREOF IN TREATING IL-8, GROα, GROβ, GROY AND NAP-2 MEDIATED DISEASES |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3599097P | 1997-01-23 | 1997-01-23 | |
| US4283097P | 1997-04-08 | 1997-04-08 | |
| PCT/US1998/001292 WO1998032438A1 (en) | 1997-01-23 | 1998-01-23 | Il-8 receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL131005A0 true IL131005A0 (en) | 2001-01-28 |
Family
ID=26712686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13100598A IL131005A0 (en) | 1997-01-23 | 1998-01-23 | Il-8 receptor antagonists |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6166055A (xx) |
| EP (1) | EP1005341B1 (xx) |
| JP (1) | JP2002515055A (xx) |
| KR (1) | KR20000070369A (xx) |
| CN (1) | CN1253501A (xx) |
| AR (1) | AR008331A1 (xx) |
| AT (1) | ATE381330T1 (xx) |
| AU (1) | AU729893B2 (xx) |
| BR (1) | BR9807085A (xx) |
| CA (1) | CA2278427A1 (xx) |
| DE (1) | DE69838874T2 (xx) |
| ES (1) | ES2299200T3 (xx) |
| HU (1) | HUP0001940A3 (xx) |
| IL (1) | IL131005A0 (xx) |
| NO (1) | NO313913B1 (xx) |
| NZ (1) | NZ336859A (xx) |
| PE (1) | PE103699A1 (xx) |
| PL (1) | PL334774A1 (xx) |
| TR (1) | TR199901761T2 (xx) |
| WO (1) | WO1998032438A1 (xx) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5929250A (en) * | 1997-01-23 | 1999-07-27 | Smithkline Beecham Corporation | IL-8 receptor antagonists |
| AR015426A1 (es) * | 1997-09-05 | 2001-05-02 | Smithkline Beecham Corp | Compuestos de benzotiazol antagonistas del receptor de il-8, composicion farmaceutica que los contiene, su uso para la manufactura de un medicamento,procedimiento para su preparacion, compuestos intermediarios y procedimiento para su preparacion |
| AR015425A1 (es) * | 1997-09-05 | 2001-05-02 | Smithkline Beecham Corp | Compuestos de benzotiazol, composicion farmaceutica que los contiene, su uso en la manufactura de un medicamento, procedimiento para su preparacion,compuestos intermediarios y procedimiento para su preparacion |
| JP2002527441A (ja) * | 1998-10-13 | 2002-08-27 | スミスクライン・ビーチャム・コーポレイション | Ｉｌ−８受容体アンタゴニスト |
| WO2000069435A1 (en) * | 1999-05-18 | 2000-11-23 | Smithkline Beecham Corporation | Il-8 receptor antagonists |
| CA2379359A1 (en) * | 1999-07-16 | 2001-01-25 | Basf Aktiengesellschaft | Process for the preparation of substituted benzisothiazole compounds |
| US6440993B1 (en) | 1999-10-12 | 2002-08-27 | Smithkline Beecham Corporation | IL-8 receptor antagonists |
| PE20011124A1 (es) | 2000-03-31 | 2001-10-28 | Upjohn Co | Nuevos agentes antibacterianos de benzosultam oxazolidinona |
| DE10038709A1 (de) | 2000-08-09 | 2002-02-28 | Aventis Pharma Gmbh | Substituierte und unsubstituierte Benzooxathiazole sowie daraus abgeleitete Verbindungen |
| GB0403038D0 (en) | 2004-02-11 | 2004-03-17 | Novartis Ag | Organic compounds |
| CA2565519A1 (en) | 2004-05-12 | 2005-12-01 | Schering Corporation | Cxcr1 and cxcr2 chemokine antagonists |
| AR065369A1 (es) | 2007-02-19 | 2009-06-03 | Novartis Ag | Derivados de ciclohexil - amida del acido aril- carboxilico |
| EP2855458B1 (en) | 2012-05-11 | 2018-08-08 | Reset Therapeutics, Inc. | Carbazole-containing sulfonamides as cryptochrome modulators |
| TWI690521B (zh) | 2014-04-07 | 2020-04-11 | 美商同步製藥公司 | 作為隱花色素調節劑之含有咔唑之醯胺類、胺基甲酸酯類及脲類 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995028399A1 (en) * | 1994-04-15 | 1995-10-26 | Glaxo Wellcome Inc. | A method of inducing cholecystokinin agonist activity using 1,4-benzodiazepine compounds |
| JP3720395B2 (ja) * | 1994-09-20 | 2005-11-24 | 京都薬品工業株式会社 | 新規ヘテロ環誘導体、その製造方法およびその医薬用途 |
| DE69617731T2 (de) * | 1995-10-05 | 2002-08-08 | Kyoto Pharmaceutical Industries, Ltd. | Neue heterozyklische derivate und ihre medizinische anwendung |
| US5929250A (en) * | 1997-01-23 | 1999-07-27 | Smithkline Beecham Corporation | IL-8 receptor antagonists |
| AR015425A1 (es) * | 1997-09-05 | 2001-05-02 | Smithkline Beecham Corp | Compuestos de benzotiazol, composicion farmaceutica que los contiene, su uso en la manufactura de un medicamento, procedimiento para su preparacion,compuestos intermediarios y procedimiento para su preparacion |
| AR015426A1 (es) * | 1997-09-05 | 2001-05-02 | Smithkline Beecham Corp | Compuestos de benzotiazol antagonistas del receptor de il-8, composicion farmaceutica que los contiene, su uso para la manufactura de un medicamento,procedimiento para su preparacion, compuestos intermediarios y procedimiento para su preparacion |
| JP2002509105A (ja) * | 1998-01-16 | 2002-03-26 | スミスクライン・ビーチャム・コーポレイション | Ｉｌ−８受容体アンタゴニスト |
-
1998
- 1998-01-22 AR ARP980100284A patent/AR008331A1/es not_active Application Discontinuation
- 1998-01-23 CN CN98803564A patent/CN1253501A/zh active Pending
- 1998-01-23 WO PCT/US1998/001292 patent/WO1998032438A1/en active IP Right Grant
- 1998-01-23 KR KR1019997006602A patent/KR20000070369A/ko not_active Application Discontinuation
- 1998-01-23 HU HU0001940A patent/HUP0001940A3/hu unknown
- 1998-01-23 AT AT98901852T patent/ATE381330T1/de not_active IP Right Cessation
- 1998-01-23 DE DE69838874T patent/DE69838874T2/de not_active Expired - Fee Related
- 1998-01-23 US US09/341,382 patent/US6166055A/en not_active Expired - Fee Related
- 1998-01-23 TR TR1999/01761T patent/TR199901761T2/xx unknown
- 1998-01-23 JP JP53213998A patent/JP2002515055A/ja not_active Ceased
- 1998-01-23 AU AU58278/98A patent/AU729893B2/en not_active Ceased
- 1998-01-23 ES ES98901852T patent/ES2299200T3/es not_active Expired - Lifetime
- 1998-01-23 BR BR9807085-1A patent/BR9807085A/pt not_active Application Discontinuation
- 1998-01-23 CA CA002278427A patent/CA2278427A1/en not_active Abandoned
- 1998-01-23 NZ NZ336859A patent/NZ336859A/xx unknown
- 1998-01-23 EP EP98901852A patent/EP1005341B1/en not_active Expired - Lifetime
- 1998-01-23 IL IL13100598A patent/IL131005A0/xx unknown
- 1998-01-23 PL PL98334774A patent/PL334774A1/xx unknown
- 1998-07-22 PE PE1998000656A patent/PE103699A1/es not_active Application Discontinuation
-
1999
- 1999-07-22 NO NO19993585A patent/NO313913B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69838874D1 (de) | 2008-01-31 |
| DE69838874T2 (de) | 2008-12-04 |
| WO1998032438A1 (en) | 1998-07-30 |
| HUP0001940A2 (hu) | 2001-01-29 |
| KR20000070369A (ko) | 2000-11-25 |
| PE103699A1 (es) | 1999-12-30 |
| US6166055A (en) | 2000-12-26 |
| AU729893B2 (en) | 2001-02-15 |
| TR199901761T2 (xx) | 1999-10-21 |
| ES2299200T3 (es) | 2008-05-16 |
| HUP0001940A3 (en) | 2002-09-30 |
| AR008331A1 (es) | 1999-12-29 |
| BR9807085A (pt) | 2000-04-18 |
| EP1005341A4 (en) | 2004-09-08 |
| NO993585L (no) | 1999-09-21 |
| NO313913B1 (no) | 2002-12-23 |
| AU5827898A (en) | 1998-08-18 |
| EP1005341A1 (en) | 2000-06-07 |
| PL334774A1 (en) | 2000-03-13 |
| NZ336859A (en) | 2001-01-26 |
| EP1005341B1 (en) | 2007-12-19 |
| NO993585D0 (no) | 1999-07-22 |
| CN1253501A (zh) | 2000-05-17 |
| JP2002515055A (ja) | 2002-05-21 |
| ATE381330T1 (de) | 2008-01-15 |
| CA2278427A1 (en) | 1998-07-30 |
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