IL130040A - Process for the solid phase synthesis of aldehydes, ketones, oximes and hydroxamic acid compounds - Google Patents

Process for the solid phase synthesis of aldehydes, ketones, oximes and hydroxamic acid compounds

Info

Publication number
IL130040A
IL130040A IL13004097A IL13004097A IL130040A IL 130040 A IL130040 A IL 130040A IL 13004097 A IL13004097 A IL 13004097A IL 13004097 A IL13004097 A IL 13004097A IL 130040 A IL130040 A IL 130040A
Authority
IL
Israel
Prior art keywords
oximes
aldehydes
ketones
solid phase
acid compounds
Prior art date
Application number
IL13004097A
Other languages
English (en)
Other versions
IL130040A0 (en
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Priority to IL155120A priority Critical patent/IL155120A/en
Publication of IL130040A0 publication Critical patent/IL130040A0/xx
Publication of IL130040A publication Critical patent/IL130040A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/30—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds
    • C07C209/42—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitrogen-to-nitrogen bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C07C239/08—Hydroxylamino compounds or their ethers or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C07C239/08—Hydroxylamino compounds or their ethers or esters
    • C07C239/20—Hydroxylamino compounds or their ethers or esters having oxygen atoms of hydroxylamino groups etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/50—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals
    • C07C251/54—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/08—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/10—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C291/00—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00
    • C07C291/02—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/516—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of nitrogen-containing compounds to >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/12—[b,e]-condensed
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/02—Alkylation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/10—Acylation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/12—Hydrolysis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/18—Introducing halogen atoms or halogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/34—Introducing sulfur atoms or sulfur-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2800/00—Copolymer characterised by the proportions of the comonomers expressed
    • C08F2800/20—Copolymer characterised by the proportions of the comonomers expressed as weight or mass percentages
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2810/00—Chemical modification of a polymer
    • C08F2810/30—Chemical modification of a polymer leading to the formation or introduction of aliphatic or alicyclic unsaturated groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Indole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
IL13004097A 1996-12-19 1997-12-17 Process for the solid phase synthesis of aldehydes, ketones, oximes and hydroxamic acid compounds IL130040A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL155120A IL155120A (en) 1996-12-19 1997-12-17 Process for the solid state synthesis of aldehydes, ketones, oximes and hydroxamic acids

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3245396P 1996-12-19 1996-12-19
US3388196P 1996-12-24 1996-12-24
PCT/US1997/023920 WO1998029376A1 (en) 1996-12-19 1997-12-17 Process for the solid phase synthesis of aldehydes, ketones, oximes, amines and hydroxamic acid compounds

Publications (2)

Publication Number Publication Date
IL130040A0 IL130040A0 (en) 2000-06-01
IL130040A true IL130040A (en) 2003-12-10

Family

ID=26708452

Family Applications (2)

Application Number Title Priority Date Filing Date
IL13004097A IL130040A (en) 1996-12-19 1997-12-17 Process for the solid phase synthesis of aldehydes, ketones, oximes and hydroxamic acid compounds
IL155120A IL155120A (en) 1996-12-19 1997-12-17 Process for the solid state synthesis of aldehydes, ketones, oximes and hydroxamic acids

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL155120A IL155120A (en) 1996-12-19 1997-12-17 Process for the solid state synthesis of aldehydes, ketones, oximes and hydroxamic acids

Country Status (24)

Country Link
EP (2) EP0946478B1 (pl)
JP (1) JP4176153B2 (pl)
KR (3) KR100604109B1 (pl)
CN (3) CN1132807C (pl)
AP (1) AP1735A (pl)
AT (1) ATE353865T1 (pl)
AU (1) AU738430B2 (pl)
BG (1) BG64153B1 (pl)
BR (1) BR9713773A (pl)
CA (1) CA2275620A1 (pl)
CZ (1) CZ299692B6 (pl)
DE (1) DE69737360T2 (pl)
DK (1) DK0946478T3 (pl)
EA (1) EA002478B1 (pl)
ES (1) ES2280085T3 (pl)
HU (1) HUP0000313A3 (pl)
IL (2) IL130040A (pl)
NO (1) NO992896L (pl)
OA (1) OA11063A (pl)
PL (1) PL195867B1 (pl)
PT (1) PT946478E (pl)
SK (1) SK286096B6 (pl)
UA (1) UA67733C2 (pl)
WO (1) WO1998029376A1 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6133409A (en) * 1996-12-19 2000-10-17 Aventis Pharmaceuticals Products Inc. Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
US6392010B1 (en) 1996-12-19 2002-05-21 Aventis Pharmaceuticals Inc. Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
US6187924B1 (en) 1997-11-12 2001-02-13 Darwin Discovery, Ltd. Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity
WO1999025752A1 (en) * 1997-11-18 1999-05-27 Aventis Pharmaceuticals Products Inc. Functionalized resin for the synthesis of amides and peptides
US6787308B2 (en) 1998-07-30 2004-09-07 Solexa Ltd. Arrayed biomolecules and their use in sequencing
US6951958B1 (en) 1999-08-03 2005-10-04 Acadia Pharmaceuticals Inc. Solid phase parallel synthesis of tertiary amines
WO2001009081A1 (en) * 1999-08-03 2001-02-08 Acadia Pharmaceuticals, Inc. Solid phase parallel synthesis of tertiary amines
US7985874B2 (en) * 2004-03-31 2011-07-26 Sumitomo Bakelite Company, Ltd. Polymer particle
CN100365006C (zh) * 2004-06-24 2008-01-30 华东理工大学 一种从生物质水解发酵废液中回收木糖的方法
WO2006029023A2 (en) * 2004-09-02 2006-03-16 Isis Pharmaceuticals, Inc. Polymeric beads for oligonucleotide synthesis
HRP20110404T1 (hr) * 2005-11-08 2011-08-31 Ambrx Ubrzivači za modifikaciju ne-prirodnih aminokiselina i polipeptida ne-prirodnih aminokiselina
WO2009096545A1 (ja) * 2008-01-30 2009-08-06 Unimatec Co., Ltd. 新規ジウレタン化合物、その製造法およびそれを含有するアクリルゴム組成物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9503749D0 (en) * 1995-02-24 1995-04-12 British Biotech Pharm Synthesis of hydroxamic acid derivatives
WO1997024117A1 (en) * 1996-01-02 1997-07-10 Rhone-Poulenc Rorer Pharmaceuticals Inc. Substituted (aryl, heteroaryl, arylmethyl or heteroarylmethyl) hydroxamic acid compounds

Also Published As

Publication number Publication date
BG103501A (en) 2000-03-31
SK75499A3 (en) 2000-03-13
HK1023989A1 (en) 2000-09-29
IL155120A0 (en) 2003-10-31
CA2275620A1 (en) 1998-07-09
CZ220899A3 (cs) 1999-11-17
PL195867B1 (pl) 2007-11-30
AP9901549A0 (en) 1999-06-30
NO992896D0 (no) 1999-06-14
UA67733C2 (uk) 2004-07-15
CN1238323C (zh) 2006-01-25
ES2280085T3 (es) 2007-09-01
EA002478B1 (ru) 2002-06-27
AU5719998A (en) 1998-07-31
KR100624995B1 (ko) 2006-09-20
EP0946478B1 (en) 2007-02-14
NO992896L (no) 1999-08-13
CN1240418A (zh) 2000-01-05
CN1132807C (zh) 2003-12-31
EA199900556A1 (ru) 2000-06-26
CZ299692B6 (cs) 2008-10-22
KR20050074660A (ko) 2005-07-18
EP0946478A1 (en) 1999-10-06
SK286096B6 (sk) 2008-03-05
EP1674484A3 (en) 2010-06-30
WO1998029376A1 (en) 1998-07-09
PL334196A1 (en) 2000-02-14
KR100604109B1 (ko) 2006-07-28
DE69737360T2 (de) 2007-10-31
ATE353865T1 (de) 2007-03-15
OA11063A (en) 2002-03-12
EP0946478A4 (en) 2004-09-08
DE69737360D1 (de) 2007-03-29
DK0946478T3 (da) 2007-05-21
IL155120A (en) 2008-06-05
CN1496999A (zh) 2004-05-19
HK1064392A1 (en) 2005-01-28
IL130040A0 (en) 2000-06-01
HUP0000313A3 (en) 2002-06-28
EP1674484A2 (en) 2006-06-28
PT946478E (pt) 2007-04-30
CN1235925C (zh) 2006-01-11
AU738430B2 (en) 2001-09-20
KR20000057690A (ko) 2000-09-25
KR20050085939A (ko) 2005-08-29
CN1500769A (zh) 2004-06-02
HUP0000313A2 (hu) 2000-06-28
BG64153B1 (bg) 2004-02-27
JP2001512419A (ja) 2001-08-21
JP4176153B2 (ja) 2008-11-05
BR9713773A (pt) 2000-03-21
AP1735A (en) 2007-05-02
KR100535170B1 (ko) 2005-12-09

Similar Documents

Publication Publication Date Title
IL155120A0 (en) Process for the solid phase synthesis of aldehydes, ketones, oximes and hydroxamic acid compounds
ZA992877B (en) Process for the preparation of hyndrocarbons from synthesis gas.
AU4977999A (en) Improved process for the synthesis of oligonucleotides and analogues thereof
AU6792894A (en) Fe1-xo-based catalyst for ammonia synthesis
ZA987554B (en) Methods for the solid phase synthesis of substituted indole compounds.
DE3565398D1 (en) Process for the synthesis of o-substituted oxime compounds and the conversion thereof into the corresponding hydroxylamine o-substituted
ZA976596B (en) Process for the catalytic preparation of n-acylglycine derivatives
ZA973575B (en) Process for preparing catalytically active coatings for the synthesis of hydrogen cyanide.
IL139796A0 (en) PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDE, KETONE, OXIME, AMINE, HYDROXAMIC ACID AND α,β UNSATURATED CAROBOXYLIC ACID AND ALDEHYDE COMPOUNDS
SI0946478T1 (sl) Postopek za sintezo v trdni fazi aldehidov, ketonov in spojin hidroksamske kisline
EA199900284A3 (ru) Способ получения гидроксамовых кислот
AU5796399A (en) Improved process for the synthesis of oligonucleotides incorporating 2-aminoadenosine
HK1032582A (en) Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and alpha, beta-unsaturated carboxylic acid and aldehyde compounds
AU3060099A (en) Catalyst for the synthesis of ammonia from hydrogen and nitrogen
ZA881961B (en) New process for the synthesis of the alpha-(1-methylethyl)-3,4-dimethoxybenzeneacetonitrile
AU4263597A (en) Process for the removal of odor from reaction product mixtures of alkylthioethanamines and their acid salts
AU3546995A (en) Improved procedure for the solid phase synthesis of oligonucleotides
AU1716799A (en) Process for removal of cyanide from reactions producing 1,3 diones
MXPA01001471A (es) Nuevo proceso para la sintesis de exoquelinas.
IL114451A (en) Process for the preparation of 5-aryl 2,4-dialkyl 3h - 1,2,4-triazole -3-thiones
ZA975058B (en) Process for the preparation of substituted cycloalkyl ketones.
ZA982828B (en) Methods and compounds for the selective inhibition of cyclooxygenase-2
IL137217A0 (en) Solid supported synthesis of hydroxamic acids
GB9810340D0 (en) A novel catalyst or pro-catalyst and a process for the catalytic,asymmetric hydrocyanation or silylcyanation of aldehydes and ketones
SI0915866T1 (en) Improved process for the synthesis of protected esters of (s)-3,4-dihydroxybutyric acid

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees