IL130009A0 - Post-mitotic neurons containing adenovirus vectors that modulate apoptosis and growth - Google Patents

Post-mitotic neurons containing adenovirus vectors that modulate apoptosis and growth

Info

Publication number
IL130009A0
IL130009A0 IL13000997A IL13000997A IL130009A0 IL 130009 A0 IL130009 A0 IL 130009A0 IL 13000997 A IL13000997 A IL 13000997A IL 13000997 A IL13000997 A IL 13000997A IL 130009 A0 IL130009 A0 IL 130009A0
Authority
IL
Israel
Prior art keywords
growth
post
adenovirus vectors
modulate apoptosis
containing adenovirus
Prior art date
Application number
IL13000997A
Other languages
English (en)
Original Assignee
Univ Mcgill
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Mcgill filed Critical Univ Mcgill
Publication of IL130009A0 publication Critical patent/IL130009A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL13000997A 1996-11-18 1997-11-18 Post-mitotic neurons containing adenovirus vectors that modulate apoptosis and growth IL130009A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3105796P 1996-11-18 1996-11-18
PCT/IB1997/001619 WO1998022608A2 (en) 1996-11-18 1997-11-18 Post-mitotic neurons containing adenovirus vectors that modulate apoptosis and growth

Publications (1)

Publication Number Publication Date
IL130009A0 true IL130009A0 (en) 2000-02-29

Family

ID=21857441

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13000997A IL130009A0 (en) 1996-11-18 1997-11-18 Post-mitotic neurons containing adenovirus vectors that modulate apoptosis and growth

Country Status (7)

Country Link
US (1) US6060247A (ja)
EP (1) EP0943004A2 (ja)
JP (1) JP2001505766A (ja)
AU (1) AU742696B2 (ja)
CA (1) CA2272578A1 (ja)
IL (1) IL130009A0 (ja)
WO (1) WO1998022608A2 (ja)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6551618B2 (en) * 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival
US20020009747A1 (en) * 1997-08-25 2002-01-24 Freda Diane Miller Methods and reagents for identifying modulators of neuronal apoptosis
JP2002519648A (ja) * 1997-08-25 2002-07-02 マクギル ユニバーシティ ニューロンの生存に関与する化合物を検出するためのｓｈｐ−１およびｓｈｐ−２の使用
US6811992B1 (en) * 1998-05-14 2004-11-02 Ya Fang Liu Method for identifying MLK inhibitors for the treatment of neurological conditions
JP2002542280A (ja) * 1999-04-27 2002-12-10 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 新規な治療
WO2000074726A1 (en) * 1999-06-07 2000-12-14 The J. David Gladstone Institutes METHODS AND COMPOSITIONS FOR PREVENTING p53 MEDIATED APOPTOSIS
EP1203214B1 (en) * 1999-08-05 2005-11-09 Cellomics, Inc. Optical system analysis of cells
EP1107003A1 (en) * 1999-12-09 2001-06-13 Trophos Methods for screening compounds active on neurons
CA2418179A1 (en) 2000-07-26 2002-01-31 University Of Maryland, Baltimore The protein kinase domain of the large subunit of herpes simplex type 2 ribonucleotide reductase (icp10pk) has anti-apoptopic activity
US20040049024A1 (en) * 2001-12-07 2004-03-11 Geoff Clark Compositions and methods related to the minn1 tumor suppressor gene and protein
US20040001808A1 (en) * 2002-06-07 2004-01-01 Kenneth Haglid Compositions and methods for the use of Bcl-2 transfected neurons
EP1534819B1 (en) 2002-08-21 2009-12-09 Revivicor, Inc. Porcine animals lacking any expression of functional alpha 1,3 galactosyltransferase
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
AU2004283448B2 (en) * 2003-10-21 2009-02-19 Imperial Innovations Limited Use of xenon for the prevention of programmed cell death
KR20130019457A (ko) 2004-07-26 2013-02-26 다우 글로벌 테크놀로지스 엘엘씨 균주 조작에 의한 개선된 단백질 발현 방법
US20090186097A1 (en) 2005-08-09 2009-07-23 David Lee Ayares Transgenic Ungulates Expressing CTLA4-IG and Uses Thereof
CN101680886A (zh) * 2007-03-20 2010-03-24 沃尔特及伊莱萨霍尔医学研究院 筛选方法
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
MX2009011523A (es) 2007-04-27 2009-11-09 Dow Global Technologies Inc Metodo para clasificar rapidamente huespedes microbianos para identificar ciertas cepas con rendimiento y/o calidad mejorados en la expresion de proteinas heterologas.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1536392A (en) * 1991-01-18 1992-08-27 Oncogene Science, Inc. Methods of transcriptionally modulating expression of oncogenes and tumor suppressor genes
US5747469A (en) * 1991-03-06 1998-05-05 Board Of Regents, The University Of Texas System Methods and compositions comprising DNA damaging agents and p53
US6410010B1 (en) * 1992-10-13 2002-06-25 Board Of Regents, The University Of Texas System Recombinant P53 adenovirus compositions
DK0931830T3 (da) * 1993-02-16 2001-06-11 Onyx Pharma Inc Cytopatiske vira til terapi og profylakse af neoplasi
WO1995005738A1 (en) * 1993-08-20 1995-03-02 Massachusetts Institute Of Technology Anticancer agents and apoptosis
BR9407956A (pt) * 1993-10-25 1996-11-26 Canji Inc Composiçao farmacêutica vetor de express o de adenovirus recombinante e kit par reduzir a proliferaçao de células tumorais
CA2176215C (en) * 1993-11-09 2007-06-26 James P. Trempe Stable cell lines capable of expressing the adeno-associated virus replication gene
WO1995027494A1 (en) * 1994-04-11 1995-10-19 Sloan-Kettering Institute For Cancer Research DEFECTIVE HERPES AND DEFECTIVE ADENO-ASSOCIATED VIRUS VECTORS WITH p53 FOR THE TREATMENT OF CANCER
US5723333A (en) * 1995-02-10 1998-03-03 Regents Of The University Of California Human pancreatic cell lines: developments and uses

Also Published As

Publication number Publication date
JP2001505766A (ja) 2001-05-08
WO1998022608A3 (en) 1998-09-03
AU742696B2 (en) 2002-01-10
CA2272578A1 (en) 1998-05-28
EP0943004A2 (en) 1999-09-22
US6060247A (en) 2000-05-09
AU5406498A (en) 1998-06-10
WO1998022608A2 (en) 1998-05-28

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