IL129958A - Blood product irradiation device incorporating agitation - Google Patents
Blood product irradiation device incorporating agitationInfo
- Publication number
- IL129958A IL129958A IL12995897A IL12995897A IL129958A IL 129958 A IL129958 A IL 129958A IL 12995897 A IL12995897 A IL 12995897A IL 12995897 A IL12995897 A IL 12995897A IL 129958 A IL129958 A IL 129958A
- Authority
- IL
- Israel
- Prior art keywords
- radiation source
- contiguous
- radiation
- self
- arrangement
- Prior art date
Links
- 239000010836 blood and blood product Substances 0.000 title claims abstract description 110
- 229940125691 blood product Drugs 0.000 title claims abstract description 110
- 238000013019 agitation Methods 0.000 title claims description 6
- 230000005855 radiation Effects 0.000 claims abstract description 120
- 210000004369 blood Anatomy 0.000 claims abstract description 56
- 239000008280 blood Substances 0.000 claims abstract description 56
- 238000001816 cooling Methods 0.000 claims abstract description 14
- 238000000034 method Methods 0.000 claims description 37
- 230000001678 irradiating effect Effects 0.000 claims description 27
- 230000008569 process Effects 0.000 claims description 19
- 238000006073 displacement reaction Methods 0.000 claims description 9
- 239000000306 component Substances 0.000 description 15
- 210000004027 cell Anatomy 0.000 description 13
- 229940079593 drug Drugs 0.000 description 9
- 239000003814 drug Substances 0.000 description 9
- 210000000265 leukocyte Anatomy 0.000 description 8
- 238000002360 preparation method Methods 0.000 description 7
- 238000000926 separation method Methods 0.000 description 7
- 239000000443 aerosol Substances 0.000 description 5
- 239000003146 anticoagulant agent Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 230000002186 photoactivation Effects 0.000 description 4
- 239000000523 sample Substances 0.000 description 4
- 229940127219 anticoagulant drug Drugs 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 230000003134 recirculating effect Effects 0.000 description 3
- 238000003491 array Methods 0.000 description 2
- 238000000502 dialysis Methods 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 238000010348 incorporation Methods 0.000 description 2
- 208000032839 leukemia Diseases 0.000 description 2
- 210000004698 lymphocyte Anatomy 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- 238000005362 photophoresis Methods 0.000 description 2
- 230000002441 reversible effect Effects 0.000 description 2
- 239000010409 thin film Substances 0.000 description 2
- 208000023275 Autoimmune disease Diseases 0.000 description 1
- QXKHYNVANLEOEG-UHFFFAOYSA-N Methoxsalen Chemical class C1=CC(=O)OC2=C1C=C1C=COC1=C2OC QXKHYNVANLEOEG-UHFFFAOYSA-N 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 229940127090 anticoagulant agent Drugs 0.000 description 1
- 230000010100 anticoagulation Effects 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 239000012503 blood component Substances 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 208000018631 connective tissue disease Diseases 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000005202 decontamination Methods 0.000 description 1
- 230000003588 decontaminative effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037765 diseases and disorders Diseases 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 230000009760 functional impairment Effects 0.000 description 1
- 238000007429 general method Methods 0.000 description 1
- 238000005534 hematocrit Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000010355 oscillation Effects 0.000 description 1
- 238000012261 overproduction Methods 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- ZCCUUQDIBDJBTK-UHFFFAOYSA-N psoralen Chemical class C1=C2OC(=O)C=CC2=CC2=C1OC=C2 ZCCUUQDIBDJBTK-UHFFFAOYSA-N 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
- A61M1/301—Details
- A61M1/303—Details having a reservoir for treated blood to be returned
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
- A61M1/301—Details
- A61M1/305—Control of inversion point between collection and re-infusion phase
- A61M1/308—Volume control, e.g. with open or flexible containers, by counting the number of pump revolutions, weighing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
- A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
- A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/025—Means for agitating or shaking blood containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/05—General characteristics of the apparatus combined with other kinds of therapy
- A61M2205/051—General characteristics of the apparatus combined with other kinds of therapy with radiation therapy
- A61M2205/053—General characteristics of the apparatus combined with other kinds of therapy with radiation therapy ultraviolet
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- External Artificial Organs (AREA)
- Beans For Foods Or Fodder (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Processing Of Meat And Fish (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3164896P | 1996-11-22 | 1996-11-22 | |
| US4679497P | 1997-04-18 | 1997-04-18 | |
| PCT/US1997/021490 WO1998022164A1 (en) | 1996-11-22 | 1997-11-19 | Blood product irradiation device incorporating agitation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL129958A0 IL129958A0 (en) | 2000-02-29 |
| IL129958A true IL129958A (en) | 2004-05-12 |
Family
ID=26707475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12995897A IL129958A (en) | 1996-11-22 | 1997-11-19 | Blood product irradiation device incorporating agitation |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0951305B1 (pt) |
| JP (1) | JP4180116B2 (pt) |
| AT (2) | ATE350083T1 (pt) |
| AU (1) | AU5361498A (pt) |
| BR (1) | BR9713528A (pt) |
| CA (1) | CA2272297C (pt) |
| DE (2) | DE69737219T2 (pt) |
| IL (1) | IL129958A (pt) |
| WO (1) | WO1998022164A1 (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6773608B1 (en) | 1998-05-13 | 2004-08-10 | Uv Pure Technologies Inc. | Ultraviolet treatment for aqueous liquids |
| DE19904088A1 (de) * | 1999-02-02 | 2000-09-07 | Fressenius Hemocare Gmbh | Schlauchset für einen Zellseparator zum Separieren von Blut in seine Komponenten und Verfahren zum Separieren von Blut in seine Komponenten |
| US6219584B1 (en) | 1999-07-09 | 2001-04-17 | Therakos, Inc. | Method and system for determining an effective amount of light energy to delivery to fluids having targets for the light energy |
| US6495366B1 (en) | 1999-09-03 | 2002-12-17 | Therakos, Inc. | Uninterrupted flow pump apparatus and method |
| US7479123B2 (en) * | 2002-03-04 | 2009-01-20 | Therakos, Inc. | Method for collecting a desired blood component and performing a photopheresis treatment |
| WO2003090795A1 (en) * | 2002-04-26 | 2003-11-06 | Gambro, Inc. | Apparatus and method for irradiating and mixing fluids in containers |
| US20070102858A1 (en) | 2005-11-07 | 2007-05-10 | Navigant Biotechnologies, Inc. | Clamps and methods for displacing fluid from portions of fluid containers |
| US8940228B2 (en) | 2012-01-11 | 2015-01-27 | Terumo Bct, Inc. | Slidable clamp for port isolation |
| US9399093B2 (en) | 2012-01-27 | 2016-07-26 | Fenwal, Inc. | Systems and methods for performing online extracorporeal photopheresis |
| US9814899B2 (en) | 2013-07-03 | 2017-11-14 | Uvlrx Therapeutics, Inc. | Systems and methods for in vivo irradiation of blood |
| EP3017329A4 (en) | 2013-07-03 | 2017-02-22 | UVLRX Therapeutics Inc. | Sheathed optical fiber |
| US10434240B2 (en) | 2015-08-17 | 2019-10-08 | Fenwal, Inc. | Methods and systems for processing and washing a photopheresis mononuclear cell product |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4321919A (en) | 1979-12-11 | 1982-03-30 | Leukocyte Research, Inc. | Method and system for externally treating human blood |
| US4428744A (en) | 1979-12-11 | 1984-01-31 | Frederic A. Bourke, Jr. | Method and system for externally treating the blood |
| US4398906A (en) | 1979-12-11 | 1983-08-16 | Frederic A. Bourke, Jr. | Method for externally treating the blood |
| US4464166A (en) | 1981-06-12 | 1984-08-07 | Frederic A. Bourke, Jr. | Method for externally treating the blood |
| US4727027A (en) | 1983-05-02 | 1988-02-23 | Diamond Scientific Co. | Photochemical decontamination treatment of whole blood or blood components |
| US4692138A (en) * | 1984-10-29 | 1987-09-08 | Mcneilab, Inc. | Pump block for interfacing irradiation chamber to photoactivation patient treatment system |
| US4737140A (en) | 1984-10-29 | 1988-04-12 | Mcneilab, Inc. | Irradiation chamber for photoactivation patient treatment system |
| US4708715A (en) | 1984-10-29 | 1987-11-24 | Mcneilab, Inc. | Light array assembly for photoactivation patient treatment system |
| US4647279A (en) | 1985-10-18 | 1987-03-03 | Cobe Laboratories, Inc. | Centrifugal separator |
| US4708712A (en) | 1986-03-28 | 1987-11-24 | Cobe Laboratories, Inc. | Continuous-loop centrifugal separator |
| US4952812A (en) | 1986-08-26 | 1990-08-28 | Baxter International Inc. | Irradiation of blood products |
| US4726949A (en) | 1986-08-26 | 1988-02-23 | Baxter Travenol Laboratories, Inc. | Irradiation of blood products |
| US4850995A (en) | 1987-08-19 | 1989-07-25 | Cobe Laboratories, Inc. | Centrifugal separation of blood |
| CA2141803C (en) * | 1992-08-07 | 2003-06-17 | Lily Lin | Methods for inactivating bacteria in blood preparations with 8-methoxypsoralen |
| DE4235841A1 (de) * | 1992-10-23 | 1994-04-28 | Steiger Erwin | Verfahren und Vorrichtung zur selektiven Zerstörung von Tumorviren, insbesondere von AIDS-Viren, mittels Laserbestrahlung |
| US5459322A (en) * | 1993-12-14 | 1995-10-17 | Therakos, Inc. | Ultraviolet light chamber |
-
1997
- 1997-11-19 CA CA002272297A patent/CA2272297C/en not_active Expired - Lifetime
- 1997-11-19 BR BR9713528A patent/BR9713528A/pt not_active Application Discontinuation
- 1997-11-19 WO PCT/US1997/021490 patent/WO1998022164A1/en active IP Right Grant
- 1997-11-19 IL IL12995897A patent/IL129958A/en not_active IP Right Cessation
- 1997-11-19 DE DE69737219T patent/DE69737219T2/de not_active Expired - Lifetime
- 1997-11-19 EP EP97950674A patent/EP0951305B1/en not_active Expired - Lifetime
- 1997-11-19 JP JP52396198A patent/JP4180116B2/ja not_active Expired - Lifetime
- 1997-11-19 AT AT03078677T patent/ATE350083T1/de active
- 1997-11-19 DE DE69731308T patent/DE69731308T2/de not_active Expired - Lifetime
- 1997-11-19 AU AU53614/98A patent/AU5361498A/en not_active Abandoned
- 1997-11-19 AT AT97950674T patent/ATE279952T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| AU5361498A (en) | 1998-06-10 |
| DE69731308T2 (de) | 2005-11-17 |
| EP0951305A1 (en) | 1999-10-27 |
| DE69731308D1 (de) | 2004-11-25 |
| EP0951305B1 (en) | 2004-10-20 |
| WO1998022164A1 (en) | 1998-05-28 |
| JP2001504373A (ja) | 2001-04-03 |
| JP4180116B2 (ja) | 2008-11-12 |
| DE69737219D1 (de) | 2007-02-15 |
| DE69737219T2 (de) | 2007-11-08 |
| BR9713528A (pt) | 2000-03-21 |
| CA2272297A1 (en) | 1998-05-28 |
| CA2272297C (en) | 2007-07-31 |
| IL129958A0 (en) | 2000-02-29 |
| ATE350083T1 (de) | 2007-01-15 |
| ATE279952T1 (de) | 2004-11-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US5951509A (en) | Blood product irradiation device incorporating agitation | |
| JP2920327B2 (ja) | 血液製品の製造法 | |
| CA2272297C (en) | Blood product irradiation device incorporating agitation | |
| US4866282A (en) | Irradiation of blood products | |
| EP0885018B1 (en) | Method and apparatus for inactivating contaminants in biological fluid | |
| US6582386B2 (en) | Multi-purpose, automated blood and fluid processing systems and methods | |
| US6706008B2 (en) | Automated system and method for withdrawing compounds from blood | |
| CA1341221C (en) | Irradiation of blood products | |
| US6808503B2 (en) | Automated system and method for pre-surgical blood donation and fluid replacement | |
| US4950225A (en) | Method for extracorporeal blood shear treatment | |
| CA2331404C (en) | Methods and apparatus for inactivating contaminants in biological fluid | |
| JP2005511209A (ja) | 病原体不活性化のために調整された血液成分を提供するための、手動の処理システムおよび方法 | |
| JP6756474B2 (ja) | 単核細胞の採集のための方法とシステム | |
| JPS61109576A (ja) | 三段階照射処理方法 | |
| CA1253115A (en) | Apparatus and methods for treating cells with radiation | |
| US20170028121A1 (en) | Irradiation device for biological fluids | |
| US11504463B2 (en) | Systems and methods for verifying that a biological product is ready for treatment | |
| EP1400253B1 (en) | Blood product irradiation device incorporating agitation | |
| US20200188685A1 (en) | Systems and Methods for Treating a Biological Fluid with Light in the Event of a Bulb Outage | |
| US20200330628A1 (en) | Systems and methods for photoactivation of a biological fluid | |
| US20190184087A1 (en) | System and method of collecting and infusing an apoptotic white blood cell component and a transplant component | |
| DE2456932A1 (de) | Magnetfeld-oxygenatorenanlage zum gasaustausch zwischen blut und einer gasatmosphaere im magnetischen feld |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| EXP | Patent expired |