IL126416A - Cultured inner cell mass cell lines derived from ungulate embryos - Google Patents
Cultured inner cell mass cell lines derived from ungulate embryosInfo
- Publication number
- IL126416A IL126416A IL12641697A IL12641697A IL126416A IL 126416 A IL126416 A IL 126416A IL 12641697 A IL12641697 A IL 12641697A IL 12641697 A IL12641697 A IL 12641697A IL 126416 A IL126416 A IL 126416A
- Authority
- IL
- Israel
- Prior art keywords
- cells
- cell
- cicm
- icm
- cultured
- Prior art date
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
- C12N15/877—Techniques for producing new mammalian cloned embryos
- C12N15/8771—Bovine embryos
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/235—Leukemia inhibitory factor [LIF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Developmental Biology & Embryology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Cell Biology (AREA)
- Environmental Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biodiversity & Conservation Biology (AREA)
- Animal Husbandry (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/626,054 US5905042A (en) | 1996-04-01 | 1996-04-01 | Cultured inner cell mass cell lines derived from bovine or porcine embryos |
| PCT/US1997/004736 WO1997037009A1 (en) | 1996-04-01 | 1997-03-24 | Cultured inner cell mass cell lines derived from ungulate embryos |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL126416A0 IL126416A0 (en) | 1999-05-09 |
| IL126416A true IL126416A (en) | 2004-06-20 |
Family
ID=24508762
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12641697A IL126416A (en) | 1996-04-01 | 1997-03-24 | Cultured inner cell mass cell lines derived from ungulate embryos |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5905042A (zh) |
| EP (1) | EP0938550B1 (zh) |
| JP (1) | JP2000507827A (zh) |
| CN (1) | CN100335625C (zh) |
| AT (1) | ATE318307T1 (zh) |
| AU (1) | AU717529B2 (zh) |
| BR (1) | BR9710652A (zh) |
| CA (1) | CA2250834A1 (zh) |
| DE (1) | DE69735293T2 (zh) |
| ES (1) | ES2259189T3 (zh) |
| IL (1) | IL126416A (zh) |
| NZ (1) | NZ332159A (zh) |
| WO (1) | WO1997037009A1 (zh) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5480772A (en) | 1993-02-03 | 1996-01-02 | Brandeis University | In vitro activation of a nucleus |
| US5523226A (en) | 1993-05-14 | 1996-06-04 | Biotechnology Research And Development Corp. | Transgenic swine compositions and methods |
| US5994619A (en) * | 1996-04-01 | 1999-11-30 | University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus | Production of chimeric bovine or porcine animals using cultured inner cell mass cells |
| US20060021070A1 (en) * | 1996-04-01 | 2006-01-26 | University of Massachusetts, a Public Institution of Higher Education of the Commonwealth of MA | Production of chimeric bovine or porcine animals using cultured inner cell mass |
| US5905042A (en) * | 1996-04-01 | 1999-05-18 | University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus | Cultured inner cell mass cell lines derived from bovine or porcine embryos |
| US7696404B2 (en) * | 1996-08-19 | 2010-04-13 | Advanced Cell Technology, Inc. | Embryonic or stem-like cell lines produced by cross species nuclear transplantation and methods for enhancing embryonic development by genetic alteration of donor cells or by tissue culture conditions |
| US6215041B1 (en) | 1997-01-10 | 2001-04-10 | University Of Mmassachusetts | Cloning using donor nuclei from a non-quiesecent somatic cells |
| US6235969B1 (en) * | 1997-01-10 | 2001-05-22 | University Of Massachusetts | Cloning pigs using donor nuclei from non-quiescent differentiated cells |
| US5945577A (en) * | 1997-01-10 | 1999-08-31 | University Of Massachusetts As Represented By Its Amherst Campus | Cloning using donor nuclei from proliferating somatic cells |
| GB9703550D0 (en) * | 1997-02-20 | 1997-04-09 | Ppl Therapeutics Scotland Ltd | Cell mediated transgenesis |
| US6011197A (en) | 1997-03-06 | 2000-01-04 | Infigen, Inc. | Method of cloning bovines using reprogrammed non-embryonic bovine cells |
| US6331659B1 (en) | 1998-01-21 | 2001-12-18 | University Of Hawaii | Cumulus cells as nuclear donors |
| NZ506808A (en) * | 1998-03-02 | 2003-12-19 | Univ Massachusetts | Embryonic or stem-like cell lines produced by cross- species nuclear transplantation |
| GB9811859D0 (en) * | 1998-06-02 | 1998-07-29 | Biotech & Biolog Scien Res | Biological manipulation |
| NZ509861A (en) * | 1998-08-11 | 2004-01-30 | Teruhiko Wakayama | Method of performing transgenesis |
| US6781030B1 (en) | 1998-11-02 | 2004-08-24 | Trustee Of Tufts College, Ballou Hall | Methods for cloning mammals using telophase oocytes |
| US6258998B1 (en) | 1998-11-24 | 2001-07-10 | Infigen, Inc. | Method of cloning porcine animals |
| US6700037B2 (en) | 1998-11-24 | 2004-03-02 | Infigen, Inc. | Method of cloning porcine animals |
| PT1159415E (pt) | 1999-03-04 | 2010-03-31 | Revivicor Inc | Modificação genética de células somáticas e suas utilizações |
| EP1206525B1 (en) | 1999-08-24 | 2008-11-12 | Una Chen-Bettecken | Method for growing stem cells |
| IL148508A0 (en) * | 1999-09-13 | 2002-09-12 | Univ Massachusetts | Cloning pigs using donor cells of nuclei from differentiated cells and production of pluripotent porcine |
| EP2336297A3 (en) | 1999-10-28 | 2011-11-16 | University of Massachusetts | Gynogenetic or androgenetic production of pluripotent cells and cell lines, and use thereof to produce differentiated cells and tissues |
| GB2360522A (en) | 2000-03-24 | 2001-09-26 | Geron Corp | A strategy for maintaining pregnancy |
| AU2001284703B2 (en) | 2000-08-03 | 2007-03-22 | Therapeutic Human Polyclonals Inc. | Production of humanized antibodies in transgenic animals |
| EP1395652A2 (en) * | 2000-11-30 | 2004-03-10 | Stemron, Inc. | Isolated homozygous stem cells differentiated cells derived therefrom and materials and methods for making and using same |
| US20030027331A1 (en) * | 2000-11-30 | 2003-02-06 | Yan Wen Liang | Isolated homozygous stem cells, differentiated cells derived therefrom, and materials and methods for making and using same |
| US20020142397A1 (en) * | 2000-12-22 | 2002-10-03 | Philippe Collas | Methods for altering cell fate |
| US7491534B2 (en) * | 2000-12-22 | 2009-02-17 | Kirin Holdings Kabushiki Kaisha | Methods for altering cell fate to generate T-cells specific for an antigen of interest |
| EP1356035B1 (en) | 2000-12-22 | 2011-03-16 | Kyowa Hakko Kirin Co., Ltd. | Methods for cloning non-human mammals using reprogrammed donor chromatin or donor cells |
| EP1373474A2 (en) * | 2001-01-02 | 2004-01-02 | Stemron, Inc. | A method for producing a population of homozygous stem cells having a pre-selected immunophenotype and/or genotype |
| WO2002073188A1 (en) * | 2001-03-13 | 2002-09-19 | Advanced Cell Technology, Inc. | Method for generating replacement cells and/or tissues |
| WO2002078449A2 (en) * | 2001-04-02 | 2002-10-10 | Advanced Cell Technology, Inc. | Method for facilitating the production of differentiated cell types and tissues from embryonic and adult pluripotent and multipotent cells |
| US6830917B2 (en) * | 2001-12-10 | 2004-12-14 | Baxter Healthcare S.A. | Method of isolation and purification of trypsin from pronase protease and use thereof |
| EP1461421A2 (en) * | 2001-12-28 | 2004-09-29 | Cellartis AB | A method for the establishment of a pluripotent human blastocyst-derived stem cell line |
| US20050170506A1 (en) * | 2002-01-16 | 2005-08-04 | Primegen Biotech Llc | Therapeutic reprogramming, hybrid stem cells and maturation |
| US20050090004A1 (en) * | 2003-01-16 | 2005-04-28 | Sayre Chauncey B. | Stem cell maturation for all tissue lines |
| US20030134422A1 (en) * | 2002-01-16 | 2003-07-17 | Sayre Chauncey Bigelow | Stem cell maturation for all tissue lines |
| US7612250B2 (en) * | 2002-07-29 | 2009-11-03 | Trustees Of Tufts College | Nuclear transfer embryo formation method |
| US20040268422A1 (en) | 2003-04-09 | 2004-12-30 | Schatten Gerald P. | Methods for correcting mitotic spindle defects associated with somatic cell nuclear transfer in animals |
| JP5072359B2 (ja) | 2003-08-22 | 2012-11-14 | ザ ジャクソン ラボラトリー | 近交系動物の遺伝的安定性を維持するための方法 |
| US8552254B2 (en) | 2003-08-22 | 2013-10-08 | The Jackson Laboratory | Methods for maintaining genetic stability of inbred animal strains |
| US20050272149A1 (en) | 2004-06-02 | 2005-12-08 | Life & Brain Gmbh | Therapeutic delivery of adenosine into a tissue |
| US20060188491A1 (en) * | 2004-07-15 | 2006-08-24 | Primegen Biotech, Llc | Use of nuclear material to therapeutically reprogram differentiated cells |
| WO2006041910A2 (en) * | 2004-10-05 | 2006-04-20 | Trustees Of The University Of Pennsylvania | Stem cells derived from uniparental embryos and methods of use thereof |
| JP2008538898A (ja) * | 2005-04-29 | 2008-11-13 | イノベイティブ デイリー プロダクツ ピーティーワイ リミティッド アズ トラスティー フォー ザ パーティシパンツ オブ ザ コーペラティブ リサーチ センター フォー イノベイティブ デイリー プ | 哺乳動物胚から幹細胞または幹細胞様細胞を作製するための方法 |
| RU2372490C2 (ru) | 2005-04-29 | 2009-11-10 | ТЕНДИКС ДИВЕЛОПМЕНТ, ЭлЭлСи | Двигатель (варианты) |
| WO2008049161A1 (en) * | 2006-10-24 | 2008-05-02 | Adelaide Research & Innovation Pty Ltd | Method for the isolation of pluripotent cells from a pre-implantation embryo in a culture medium free from animal serum |
| WO2008085891A1 (en) * | 2007-01-05 | 2008-07-17 | Worcester Polytechnic Institute | Oocyte spindle-associated factors improve somatic cell cloning |
| WO2010108503A1 (en) | 2009-03-24 | 2010-09-30 | Life & Brain Gmbh | Promotion of neuronal integration in neural stem cell grafts |
| CN104994728B (zh) * | 2012-10-19 | 2019-02-15 | 移卵基因有限公司 | 用于产生遗传上优质的动物的方法 |
| US10266807B2 (en) | 2013-04-03 | 2019-04-23 | FUJIFILM Cellular Dynamics, Inc. | Methods and compositions for culturing endoderm progenitor cells in suspension |
| JP6581655B2 (ja) | 2014-10-14 | 2019-09-25 | フジフィルム セルラー ダイナミクス，インコーポレイテッド | 多能性幹細胞由来ケラチノサイトの生成およびケラチノサイト培養の維持 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04500909A (ja) * | 1988-09-21 | 1992-02-20 | アニマル バイオテクノロジー ケンブリッジ リミティド | 家畜からの多能性胚細胞系の誘導 |
| GB9003791D0 (en) * | 1990-02-20 | 1990-04-18 | Ludwig Inst Cancer Res | Transgenic animals,cell lines therefrom,and their use |
| US5523226A (en) * | 1993-05-14 | 1996-06-04 | Biotechnology Research And Development Corp. | Transgenic swine compositions and methods |
| AU684524B2 (en) * | 1993-06-14 | 1997-12-18 | Tet Systems Holding Gmbh & Co. Kg | Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters |
| US5905042A (en) * | 1996-04-01 | 1999-05-18 | University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus | Cultured inner cell mass cell lines derived from bovine or porcine embryos |
-
1996
- 1996-04-01 US US08/626,054 patent/US5905042A/en not_active Expired - Fee Related
-
1997
- 1997-03-24 AT AT97915189T patent/ATE318307T1/de not_active IP Right Cessation
- 1997-03-24 JP JP9535351A patent/JP2000507827A/ja active Pending
- 1997-03-24 WO PCT/US1997/004736 patent/WO1997037009A1/en active IP Right Grant
- 1997-03-24 CN CNB971947554A patent/CN100335625C/zh not_active Expired - Fee Related
- 1997-03-24 IL IL12641697A patent/IL126416A/en not_active IP Right Cessation
- 1997-03-24 CA CA002250834A patent/CA2250834A1/en not_active Abandoned
- 1997-03-24 NZ NZ332159A patent/NZ332159A/en unknown
- 1997-03-24 AU AU22194/97A patent/AU717529B2/en not_active Ceased
- 1997-03-24 BR BR9710652-6A patent/BR9710652A/pt not_active Application Discontinuation
- 1997-03-24 ES ES97915189T patent/ES2259189T3/es not_active Expired - Lifetime
- 1997-03-24 DE DE69735293T patent/DE69735293T2/de not_active Expired - Fee Related
- 1997-03-24 EP EP97915189A patent/EP0938550B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0938550B1 (en) | 2006-02-22 |
| EP0938550A4 (en) | 2001-08-08 |
| IL126416A0 (en) | 1999-05-09 |
| WO1997037009A1 (en) | 1997-10-09 |
| CN1219198A (zh) | 1999-06-09 |
| NZ332159A (en) | 2000-02-28 |
| CN100335625C (zh) | 2007-09-05 |
| ATE318307T1 (de) | 2006-03-15 |
| EP0938550A1 (en) | 1999-09-01 |
| US5905042A (en) | 1999-05-18 |
| JP2000507827A (ja) | 2000-06-27 |
| CA2250834A1 (en) | 1997-10-09 |
| BR9710652A (pt) | 2000-01-11 |
| DE69735293D1 (de) | 2006-04-27 |
| DE69735293T2 (de) | 2006-11-02 |
| ES2259189T3 (es) | 2006-09-16 |
| AU717529B2 (en) | 2000-03-30 |
| AU2219497A (en) | 1997-10-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |