IL123780A - In vitro method of producing polyphenolic polymers by contacting extracellular recombinant tyrosinase with selected tyrosinase substrates - Google Patents

In vitro method of producing polyphenolic polymers by contacting extracellular recombinant tyrosinase with selected tyrosinase substrates

Info

Publication number
IL123780A
IL123780A IL12378093A IL12378093A IL123780A IL 123780 A IL123780 A IL 123780A IL 12378093 A IL12378093 A IL 12378093A IL 12378093 A IL12378093 A IL 12378093A IL 123780 A IL123780 A IL 123780A
Authority
IL
Israel
Prior art keywords
tyrosinase
vitro method
substrates
polyphenolic polymers
extracellular recombinant
Prior art date
Application number
IL12378093A
Other languages
English (en)
Original Assignee
Large Scale Biology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Large Scale Biology Corp filed Critical Large Scale Biology Corp
Publication of IL123780A publication Critical patent/IL123780A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G61/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0055—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10)
    • C12N9/0057—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10) with oxygen as acceptor (1.10.3)
    • C12N9/0059—Catechol oxidase (1.10.3.1), i.e. tyrosinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y110/00—Oxidoreductases acting on diphenols and related substances as donors (1.10)
    • C12Y110/03—Oxidoreductases acting on diphenols and related substances as donors (1.10) with an oxygen as acceptor (1.10.3)
    • C12Y110/03001—Catechol oxidase (1.10.3.1), i.e. tyrosinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/18—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with another compound as one donor, and incorporation of one atom of oxygen (1.14.18)
    • C12Y114/18001—Tyrosinase (1.14.18.1)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
IL12378093A 1992-11-25 1993-11-23 In vitro method of producing polyphenolic polymers by contacting extracellular recombinant tyrosinase with selected tyrosinase substrates IL123780A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/982,095 US5340734A (en) 1992-11-25 1992-11-25 Method for making stable, extracellular tyrosinase and synthesis of polyphenolic polymers therefrom
IL10772493A IL107724A (he) 1992-11-25 1993-11-23 מצע תרבית חיידקי מתאים ליצור טירוסינז חוץ-תאי עמיד

Publications (1)

Publication Number Publication Date
IL123780A true IL123780A (en) 2003-03-12

Family

ID=25528841

Family Applications (6)

Application Number Title Priority Date Filing Date
IL12378093A IL123780A (en) 1992-11-25 1993-11-23 In vitro method of producing polyphenolic polymers by contacting extracellular recombinant tyrosinase with selected tyrosinase substrates
IL12377893A IL123778A (he) 1992-11-25 1993-11-23 שיטת מבחנה ליצירת פולימרים פוליפנוליים על ידי יצירתמגע בין טירוזינאז לבין מגיבים לפעולת טירוזינאז
IL10772493A IL107724A (he) 1992-11-25 1993-11-23 מצע תרבית חיידקי מתאים ליצור טירוסינז חוץ-תאי עמיד
IL12377898A IL123778A0 (en) 1992-11-25 1998-03-22 Method for making stable extracellular tyrosinase and synthesis of polyphenolic polymers therefrom
IL12378098A IL123780A0 (en) 1992-11-25 1998-03-22 Method for making stable extracellular tyrosinase and synthesis of polyphenolic polymers therefrom
IL14047900A IL140479A0 (en) 1992-11-25 2000-12-21 A microbial culture with tyrosinase activity stabilized by reducing the amount of dissolved oxygen in the medium during tyrosinase expression

Family Applications After (5)

Application Number Title Priority Date Filing Date
IL12377893A IL123778A (he) 1992-11-25 1993-11-23 שיטת מבחנה ליצירת פולימרים פוליפנוליים על ידי יצירתמגע בין טירוזינאז לבין מגיבים לפעולת טירוזינאז
IL10772493A IL107724A (he) 1992-11-25 1993-11-23 מצע תרבית חיידקי מתאים ליצור טירוסינז חוץ-תאי עמיד
IL12377898A IL123778A0 (en) 1992-11-25 1998-03-22 Method for making stable extracellular tyrosinase and synthesis of polyphenolic polymers therefrom
IL12378098A IL123780A0 (en) 1992-11-25 1998-03-22 Method for making stable extracellular tyrosinase and synthesis of polyphenolic polymers therefrom
IL14047900A IL140479A0 (en) 1992-11-25 2000-12-21 A microbial culture with tyrosinase activity stabilized by reducing the amount of dissolved oxygen in the medium during tyrosinase expression

Country Status (9)

Country Link
US (5) US5340734A (he)
EP (1) EP0672148A1 (he)
JP (1) JPH08503613A (he)
KR (1) KR950704496A (he)
AU (1) AU689093B2 (he)
CA (1) CA2149764C (he)
IL (6) IL123780A (he)
WO (1) WO1994012644A2 (he)
ZA (1) ZA938581B (he)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6300057B1 (en) 1997-02-06 2001-10-09 Large Scale Biology Corporation Melanins with improved ability to inhibit HIV replication
US6242415B1 (en) 1997-02-12 2001-06-05 Sri International Mediation of cytokines by melanin
ITMI991896A1 (it) * 1999-09-09 2001-03-09 Carlo Ghisalberti Melanine e pigmenti vegetali
DE10007777A1 (de) * 2000-02-21 2001-09-20 Magnet Motor Gmbh Dauermagnetisch erregte elektrische Maschine und Verfahren zum Betreiben einer solchen Maschine
US7704272B2 (en) * 2002-01-31 2010-04-27 University Of Rochester Method for introducing an ultraviolet light activated viral vector into the spinal column
ATE348884T1 (de) * 2002-01-31 2007-01-15 Univ Rochester Ultraviolette licht zur lichtaktivierten gentransduktion bei der genzuführung
CA2514643A1 (en) * 2003-01-31 2004-08-19 University Of Rochester Light probe for ultraviolet light activated gene transduction
US8586090B2 (en) * 2004-10-05 2013-11-19 Albert Einstein College Of Medicine Of Yeshiva University Melanin nanoshells for protection against radiation and electronic pulses
FI118567B (fi) * 2005-02-10 2007-12-31 Valtion Teknillinen Uusia mikrobientsyymejä ja niiden käyttö
FI126442B (en) * 2011-11-01 2016-12-15 Valio Oy Liquid enzyme preparation and process for its preparation
JP2013158329A (ja) * 2012-02-08 2013-08-19 Ishikawa Prefectural Public Univ Corp チロシナーゼとペプチドとを用いた呈色反応
WO2014020517A2 (en) * 2012-07-30 2014-02-06 Myko Tech Private Limited Production of extracellular tyrosinase enzyme using the fungus gliocephalotrichum for various applications
CN107091860B (zh) * 2017-05-22 2019-06-25 苏州大学 基于金掺杂方酸菁聚合物的湿敏传感器及其制备和用途
CN116940369A (zh) 2020-09-08 2023-10-24 居里公司 组合物及其使用方法
CN117618655B (zh) * 2024-01-03 2024-09-03 中国医学科学院放射医学研究所 一种免疫调控水凝胶及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU87672A1 (fr) * 1990-02-05 1991-10-08 Oreal Procede de preparation d'un pigment melanique par voie enzymatique
US5188844A (en) * 1990-05-14 1993-02-23 Advanced Polymer Systems, Inc. Color modified melanins and methods for their preparation and use
AU8295491A (en) * 1990-06-29 1992-01-23 Biosource Technologies Incorporated Melanin production by transformed microorganisms

Also Published As

Publication number Publication date
US5340734A (en) 1994-08-23
WO1994012644A3 (en) 1995-05-04
US5792649A (en) 1998-08-11
US5466592A (en) 1995-11-14
AU689093B2 (en) 1998-03-26
IL140479A0 (en) 2002-02-10
ZA938581B (en) 1995-02-21
IL123778A0 (en) 2000-06-01
WO1994012644A2 (en) 1994-06-09
IL123780A0 (en) 1999-11-30
CA2149764A1 (en) 1994-06-09
CA2149764C (en) 2000-08-08
IL123778A (he) 2002-12-01
IL107724A (he) 2001-06-14
KR950704496A (ko) 1995-11-20
AU5896594A (en) 1994-06-22
EP0672148A1 (en) 1995-09-20
US5801047A (en) 1998-09-01
JPH08503613A (ja) 1996-04-23
US5486351A (en) 1996-01-23
IL107724A0 (en) 1994-02-27

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