MX2023002744A - Composiciones y metodos de uso de las mismas. - Google Patents

Composiciones y metodos de uso de las mismas.

Info

Publication number
MX2023002744A
MX2023002744A MX2023002744A MX2023002744A MX2023002744A MX 2023002744 A MX2023002744 A MX 2023002744A MX 2023002744 A MX2023002744 A MX 2023002744A MX 2023002744 A MX2023002744 A MX 2023002744A MX 2023002744 A MX2023002744 A MX 2023002744A
Authority
MX
Mexico
Prior art keywords
compositions
optionally
methods
disclosed
zymogen
Prior art date
Application number
MX2023002744A
Other languages
English (en)
Inventor
Erika M Milczek
Will Shindel
Original Assignee
Curie Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curie Co Inc filed Critical Curie Co Inc
Publication of MX2023002744A publication Critical patent/MX2023002744A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/104—Aminoacyltransferases (2.3.2)
    • C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50—Isolated enzymes; Isolated proteins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P1/00—Disinfectants; Antimicrobial compounds or mixtures thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0055—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10)
    • C12N9/0057—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10) with oxygen as acceptor (1.10.3)
    • C12N9/0061—Laccase (1.10.3.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
    • C12Y104/03—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C12Y104/03013—Protein-lysine 6-oxidase (1.4.3.13), i.e. lysyl-oxidase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y110/00—Oxidoreductases acting on diphenols and related substances as donors (1.10)
    • C12Y110/03—Oxidoreductases acting on diphenols and related substances as donors (1.10) with an oxygen as acceptor (1.10.3)
    • C12Y110/03002—Laccase (1.10.3.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/18—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with another compound as one donor, and incorporation of one atom of oxygen (1.14.18)
    • C12Y114/18001—Tyrosinase (1.14.18.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/02—Aminoacyltransferases (2.3.2)
    • C12Y203/02013—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/14—Dipeptidyl-peptidases and tripeptidyl-peptidases (3.4.14)
    • C12Y304/14012—Xaa-Xaa-Pro tripeptidyl-peptidase (3.4.14.12), i.e. prolyltripeptidyl aminopeptidase

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Agronomy & Crop Science (AREA)
  • Virology (AREA)
  • Dentistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)
  • Cosmetics (AREA)

Abstract

En el presente documento se describen composiciones a base de enzimas para el control y/o la conservación microbianos de amplio espectro. Las composiciones descritas incluyen enzimas reticulantes, opcionalmente, en forma de zimógeno, e incluyen péptidos antimicrobianos, proteínas, polímeros y, opcionalmente, pueden incluir conservadores químicos.
MX2023002744A 2020-09-08 2021-09-07 Composiciones y metodos de uso de las mismas. MX2023002744A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063075763P 2020-09-08 2020-09-08
PCT/US2021/049326 WO2022055902A2 (en) 2020-09-08 2021-09-07 Compositions and methods of use thereof

Publications (1)

Publication Number Publication Date
MX2023002744A true MX2023002744A (es) 2023-04-03

Family

ID=80629837

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023002744A MX2023002744A (es) 2020-09-08 2021-09-07 Composiciones y metodos de uso de las mismas.

Country Status (9)

Country Link
US (1) US20230329245A1 (es)
EP (1) EP4211233A2 (es)
JP (1) JP2023540349A (es)
KR (1) KR20230066022A (es)
CN (1) CN116940369A (es)
BR (1) BR112023003136A2 (es)
CA (1) CA3194036A1 (es)
MX (1) MX2023002744A (es)
WO (1) WO2022055902A2 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023225666A1 (en) 2022-05-20 2023-11-23 Curie Co. Inc. Pro-peptide variants for modulating activity of transglutaminases
WO2024054236A1 (en) * 2022-09-09 2024-03-14 Curie Co. Inc. Immobilized proteases for activation of the zymogen form of transglutaminase

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1225217A4 (en) * 1999-10-18 2004-06-16 Ajinomoto Kk PROCESS FOR PRODUCING TRANSGLUTAMINASE DERIVED FROM A MICROORGANISM
US8771649B2 (en) * 2003-05-30 2014-07-08 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Inducible release vehicles
WO2007030708A2 (en) * 2005-09-08 2007-03-15 Adnexus Therapeutics, Inc. Antimicrobial adzymes and uses thereof
BRPI0817228A2 (pt) * 2007-09-25 2015-06-16 Pastoral Greenhouse Gas Res Ltd Peptídeos e polipeptídeos de permeabilização de célula para células microbiais
JP6666336B2 (ja) * 2014-06-12 2020-03-13 シー・エス・ピー・シー ドフェン コーポレーションＣｓｐｃ Ｄｏｐｈｅｎ Ｃｏｒｐｏｒａｔｉｏｎ 酵素的方法による均一抗体薬物コンジュゲート
US11319531B2 (en) * 2017-11-07 2022-05-03 Codexis, Inc. Transglutaminase variants

Also Published As

Publication number Publication date
EP4211233A2 (en) 2023-07-19
WO2022055902A2 (en) 2022-03-17
CN116940369A (zh) 2023-10-24
BR112023003136A2 (pt) 2023-04-04
KR20230066022A (ko) 2023-05-12
WO2022055902A3 (en) 2022-04-21
CA3194036A1 (en) 2022-03-17
JP2023540349A (ja) 2023-09-22
US20230329245A1 (en) 2023-10-19

Similar Documents

Publication Publication Date Title
MX2023002744A (es) Composiciones y metodos de uso de las mismas.
EP3763830A4 (en) LACTOBACILLUS SP. NANOVESICLE BACTERIA DERIVED AND USES THEREOF
CA3204810A1 (en) Reprogrammable tnpb polypeptides and use thereof
WO2005047511A3 (en) Bacterial expression of protease inhibitors and variants thereof
EP4101864A4 (en) POLYPEPTIDE AND PRODUCTION PROCESS THEREOF AND USE THEREOF
MX2020006901A (es) Composiciones de pares de bases no naturales y procedimientos de uso.
AU2021289730A8 (en) BRM targeting compounds and associated methods of use
WO2021146654A8 (en) Silk coated leather and products and methods of preparing the same
MX2022015239A (es) Polímeros y conectores biocidas injertables y usos de los mismos.
WO2021248023A3 (en) Compositions and methods for epigenome editing
WO2001049721A3 (en) Bacterial genes and proteins that are essential for cell viability and their uses
DK1686170T3 (da) Ny Brevibacillus coshinensis og fremgangsnåde til produktion af protein under anvendelse af mikroorganismen som vært
WO2021203016A3 (en) Protein-protein interaction stabilizers
WO2004009252A3 (en) Wood finishes and methods for their production
WO2004070018A3 (en) Vegf-b and pdgf modulation of stem cells
MX2022011707A (es) Aplicaciones de inhibidor de fosfatidilinositol 4-cinasa (pi4k) en enfermedades relacionadas con el plegamineto incorrecto de proteinas intracelulares y enfermedades de almacenamiento lisosomal.
WO2004048421A3 (en) Branched cationic copolymers and methods for antimicrobial use
WO2021178960A3 (en) Compositions and methods for treatment of cancer
WO2020251313A3 (en) Methods and compositions for conferring and/or enhancing herbicide tolerance using protoporphyrinogen ix oxidase of various cyanobacteria or variant thereof
EP4102914A4 (en) METHOD AND TERMINAL FOR DETERMINING A SYSTEM OPERATING MODE
WO2005080420A3 (en) Hyphal growth in fungi
WO2022221479A3 (en) Magec2 immunogenic peptides, binding proteins recognizing magec2 immunogenic peptides, and uses thereof
WO2023114759A3 (en) Abl inhibitors and uses thereof
WO2022232143A3 (en) G-alpha-s peptide inhibitors and uses thereof
WO2019018845A9 (en) GROWTH AND SPORULATION OF ARBUSCULAR MYCORRHIZES