IL121165A0 - Pharmaceutical compositions containing carboxylic acids and derivatives thereof - Google Patents

Pharmaceutical compositions containing carboxylic acids and derivatives thereof

Info

Publication number
IL121165A0
IL121165A0 IL12116597A IL12116597A IL121165A0 IL 121165 A0 IL121165 A0 IL 121165A0 IL 12116597 A IL12116597 A IL 12116597A IL 12116597 A IL12116597 A IL 12116597A IL 121165 A0 IL121165 A0 IL 121165A0
Authority
IL
Israel
Prior art keywords
substituted
chain
derivatives
pharmaceutical compositions
alkyl
Prior art date
Application number
IL12116597A
Other languages
English (en)
Original Assignee
Yissum Res Dev Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Res Dev Co filed Critical Yissum Res Dev Co
Priority to IL12116597A priority Critical patent/IL121165A0/xx
Publication of IL121165A0 publication Critical patent/IL121165A0/xx
Priority to JP50539899A priority patent/JP2002507209A/ja
Priority to IL13354098A priority patent/IL133540A0/xx
Priority to CNA2007101516440A priority patent/CN101129349A/zh
Priority to EP98925875A priority patent/EP1001755B1/en
Priority to RU2000101334/15A priority patent/RU2239427C2/ru
Priority to PCT/IB1998/000968 priority patent/WO1999000116A2/en
Priority to CA002294232A priority patent/CA2294232A1/en
Priority to CN98806550A priority patent/CN1261274A/zh
Priority to AT98925875T priority patent/ATE508739T1/de
Priority to AU77839/98A priority patent/AU7783998A/en
Priority to US09/104,880 priority patent/US6303653B1/en
Priority to IL133540A priority patent/IL133540A/en
Priority to US10/735,439 priority patent/US20040171688A1/en
Priority to US10/735,452 priority patent/US20040171585A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL12116597A 1997-06-26 1997-06-26 Pharmaceutical compositions containing carboxylic acids and derivatives thereof IL121165A0 (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
IL12116597A IL121165A0 (en) 1997-06-26 1997-06-26 Pharmaceutical compositions containing carboxylic acids and derivatives thereof
AU77839/98A AU7783998A (en) 1997-06-26 1998-06-23 Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them
PCT/IB1998/000968 WO1999000116A2 (en) 1997-06-26 1998-06-23 Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them
CN98806550A CN1261274A (zh) 1997-06-26 1998-06-23 羧酸和其衍生物以及含有它们的药物组合物
CNA2007101516440A CN101129349A (zh) 1997-06-26 1998-06-23 羧酸和其衍生物以及含有它们的药物组合物
EP98925875A EP1001755B1 (en) 1997-06-26 1998-06-23 Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them
RU2000101334/15A RU2239427C2 (ru) 1997-06-26 1998-06-23 Карбоновые кислоты и их производные и содержащие их фармацевтические композиции
JP50539899A JP2002507209A (ja) 1997-06-26 1998-06-23 カルボン酸類及びその誘導体並びにそれらを含有する医薬組成物
CA002294232A CA2294232A1 (en) 1997-06-26 1998-06-23 Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them
IL13354098A IL133540A0 (en) 1997-06-26 1998-06-23 Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them
AT98925875T ATE508739T1 (de) 1997-06-26 1998-06-23 Carboxylsäuren un deren derivate und pharmazeutische zusammensetzungen die diese enthalten
US09/104,880 US6303653B1 (en) 1997-06-26 1998-06-25 Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them
IL133540A IL133540A (en) 1997-06-26 1999-12-15 Pharmaceutical compositions containing carboxylic acids and derivatives thereof
US10/735,439 US20040171688A1 (en) 1997-06-26 2003-12-11 Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them
US10/735,452 US20040171585A1 (en) 1997-06-26 2003-12-11 Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL12116597A IL121165A0 (en) 1997-06-26 1997-06-26 Pharmaceutical compositions containing carboxylic acids and derivatives thereof

Publications (1)

Publication Number Publication Date
IL121165A0 true IL121165A0 (en) 1997-11-20

Family

ID=11070308

Family Applications (2)

Application Number Title Priority Date Filing Date
IL12116597A IL121165A0 (en) 1997-06-26 1997-06-26 Pharmaceutical compositions containing carboxylic acids and derivatives thereof
IL133540A IL133540A (en) 1997-06-26 1999-12-15 Pharmaceutical compositions containing carboxylic acids and derivatives thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL133540A IL133540A (en) 1997-06-26 1999-12-15 Pharmaceutical compositions containing carboxylic acids and derivatives thereof

Country Status (10)

Country Link
US (1) US6303653B1 (https=)
EP (1) EP1001755B1 (https=)
JP (1) JP2002507209A (https=)
CN (2) CN1261274A (https=)
AT (1) ATE508739T1 (https=)
AU (1) AU7783998A (https=)
CA (1) CA2294232A1 (https=)
IL (2) IL121165A0 (https=)
RU (1) RU2239427C2 (https=)
WO (1) WO1999000116A2 (https=)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020037876A1 (en) * 1998-06-25 2002-03-28 Yissum Research Development Company Of Hebrew University Of Jerusalem Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them
MXPA01009893A (es) 1999-04-01 2003-07-28 Esperion Therapeutics Inc Compuestos con eter, composiciones y usos de estos.
WO2002009691A1 (en) * 2000-08-02 2002-02-07 Pharmanutrients Methods and compositions for the prevention and treatment of syndrome x
WO2002024227A1 (en) * 2000-09-20 2002-03-28 Kyowa Hakko Kogyo Co., Ltd. Tumor cell proliferation inhibitors
AU2002211666A1 (en) 2000-10-11 2002-04-22 Esperion Therapeutics, Inc. Sulfide and disulfide compounds and compositions for cholesterol management and related uses
MXPA03003024A (es) 2000-10-11 2003-07-14 Esperion Therapeutics Inc Compuestos de sulfoxido y bis-sulfoxido y composiciones para el control de colesterol y usos relacionados.
IL155215A0 (en) 2000-10-11 2003-11-23 Esperion Therapeutics Inc Ether compounds and compositions for cholesterol management and related uses
WO2002030860A2 (en) 2000-10-11 2002-04-18 Esperion Therapeutics, Inc. Ketone compounds and compositions for cholesterol management and related uses
US7304093B2 (en) 2000-10-11 2007-12-04 Esperion Therapeutics, Inc. Ketone compounds and compositions for cholesterol management and related uses
NO20006008L (no) * 2000-11-28 2002-05-29 Thia Medica As Fettsyreanaloger for behandling av inflammatoriske og autoimmune sykdommer
AU2003223930A1 (en) * 2002-06-14 2003-12-31 Novo Nordisk A/S Pharmaceutical use of boronic acids and esters thereof
HUE036646T2 (hu) 2003-01-23 2018-07-30 Esperion Therapeutics Inc Hidroxilvegyületek és kompozícióik koleszterin szabályozására és kapcsolódó alkalmazásokra
JP2007525408A (ja) 2003-12-24 2007-09-06 エスペリオン セラピューティクス,インコーポレイテッド コレステロール管理および関連使用のためのケトン化合物および組成物
WO2005062718A2 (en) * 2003-12-30 2005-07-14 Syndromex Ltd. Methods of administering 3,3,14,14 tetramethyl hexadecane 1,16 dioic acid
KR20050118057A (ko) * 2004-04-24 2005-12-15 김상희 아세틸디아실글리세롤류의 화합물을 유효성분으로함유하는 항암제 및 건강식품
CA2617213C (en) 2005-07-29 2014-01-28 Resverlogix Corp. Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
WO2007137864A1 (en) * 2006-06-01 2007-12-06 Eucro European Contract Research Gmbh & Co. Kg Use of inhibitors of pp2c for treating or preventing arteriosclerosis
US7777071B2 (en) 2006-08-11 2010-08-17 Ssv Therapeutics, Inc. Production of carnitine conjugate intermediates
WO2008092231A1 (en) 2007-02-01 2008-08-07 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular diseases
IL181577A0 (en) * 2007-02-26 2007-07-04 Jacob Bar Tana Combination therapy composition and methods for the treatment of cardiovascular disorders and immune-related disorders
EP2167069B1 (en) 2007-05-23 2011-10-26 Amcol International Corporation Cholesterol-interacting layered phyllosilicates and methods of reducing hypercholesteremia in a mammal
DE102007051339A1 (de) * 2007-10-26 2009-04-30 Müller-Enoch, Dieter, Prof. Dr. Verwendung von Verbindungen der Formel A-R-X oder deren pharmazeutisch akzeptablen Salze zur Herstellung einer pharmazeutischen Zubereitung zur Behandlung und zur Vorbeugung von Dyslipidämien
EP2085082A1 (en) * 2008-01-29 2009-08-05 Nutromnia S.R.L. Treatment of cognitive decline
KR101629356B1 (ko) 2008-06-26 2016-06-13 리스버로직스 코퍼레이션 퀴나졸리논 유도체의 제조방법
AU2010204106B2 (en) 2009-01-08 2014-05-08 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular disease
US10478464B2 (en) * 2009-01-14 2019-11-19 Kirit Shah Compositions and methods of use
NZ755378A (en) 2009-03-18 2022-07-29 Resverlogix Corp Novel quinazolinones and related compounds for use as anti-inflammatory agents
WO2010120534A1 (en) * 2009-03-31 2010-10-21 Whitten Matthew R System and method for radiation therapy treatment planning using a memetic optimization algorithm
KR20190091564A (ko) 2009-04-22 2019-08-06 리스버로직스 코퍼레이션 신규한 소염제
PE20161551A1 (es) 2009-09-03 2017-01-18 Pfizer Vaccines Llc Vacuna de pcsk9
US20140004142A1 (en) 2011-03-02 2014-01-02 Pfizer Inc. Pcsk9 vaccine
RU2640115C2 (ru) 2011-11-01 2017-12-26 Ресверлоджикс Корп. Фармацевтические композиции замещенных хиназолинонов
WO2013084237A1 (en) * 2011-12-08 2013-06-13 Syndromex Ltd. Deuterated tetramethyl dioic acids, compositions comprising them and uses thereof
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
US9765039B2 (en) 2012-11-21 2017-09-19 Zenith Epigenetics Ltd. Biaryl derivatives as bromodomain inhibitors
AU2013365926B9 (en) 2012-12-21 2019-01-17 Zenith Epigenetics Ltd. Novel heterocyclic compounds as bromodomain inhibitors
WO2015123291A1 (en) 2014-02-11 2015-08-20 The Usa, As Represented By The Secretary, Dept. Of Health And Human Services Pcsk9 vaccine and methods of using the same
RU2022102472A (ru) 2015-03-13 2022-03-15 Эсперион Терапеутикс, Инк. Фиксированные комбинации и составы, содержащие etc-1002 и эзетимиб, и способы лечения или уменьшения риска развития сердечно-сосудистого заболевания
JO3789B1 (ar) 2015-03-13 2021-01-31 Resverlogix Corp التراكيب والوسائل العلاجية المعتمدة لمعالجة الامراض المتعلقة بالمتممة
MA41793A (fr) 2015-03-16 2018-01-23 Esperion Therapeutics Inc Associations de doses fixes comprenant du etc1002 et une ou plusieurs statines permettant de traiter ou de réduire un risque cardiovasculaire
US20180092874A1 (en) * 2016-10-03 2018-04-05 Lincoln Memorial University Identification and use of very long chain dicarboxylic acids for disease diagnosis, chemoprevention, and treatment
WO2019010414A1 (en) * 2017-07-07 2019-01-10 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Fatty acid derivatives and their use
CN112437766A (zh) 2019-06-21 2021-03-02 艾斯柏伦治疗公司 制备贝派地酸及其组合物的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL64542A0 (en) * 1981-12-15 1982-03-31 Yissum Res Dev Co Long-chain alpha,omega-dicarboxylic acids and derivatives thereof and pharmaceutical compositions containing them
DE3423166A1 (de) 1984-06-22 1986-01-02 Epis S.A., Zug Alpha-, omega-dicarbonsaeuren, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
GB8819110D0 (en) * 1988-08-11 1988-09-14 Norsk Hydro As Antihypertensive drug & method for production
DE4224670A1 (de) 1992-07-25 1994-01-27 Boehringer Mannheim Gmbh Verwendung von â,w-Dicarbonsäuren als Fibrinogensenker
ATE183391T1 (de) * 1993-12-31 1999-09-15 Univ Limburg Verwendung von zusammensetzungen essentieller fettsäuren
IL119971A (en) 1997-01-07 2003-02-12 Yissum Res Dev Co Pharmaceutical compositions containing dicarboxylic acids and derivatives thereof and some novel dicarboxylic acids
JP2001516343A (ja) * 1997-02-21 2001-09-25 アボツト・ラボラトリーズ 壊死性全腸炎の発生を減少させるための方法及び組成物

Also Published As

Publication number Publication date
CN101129349A (zh) 2008-02-27
ATE508739T1 (de) 2011-05-15
RU2239427C2 (ru) 2004-11-10
JP2002507209A (ja) 2002-03-05
IL133540A (en) 2009-09-22
WO1999000116A3 (en) 1999-08-12
AU7783998A (en) 1999-01-19
CN1261274A (zh) 2000-07-26
EP1001755A2 (en) 2000-05-24
WO1999000116A2 (en) 1999-01-07
CA2294232A1 (en) 1999-01-07
EP1001755B1 (en) 2011-05-11
US6303653B1 (en) 2001-10-16

Similar Documents

Publication Publication Date Title
IL121165A0 (en) Pharmaceutical compositions containing carboxylic acids and derivatives thereof
HUT64512A (en) Process for preparing acetic acid derivatives containing heteroatom with lipid level reducing activity and pharmaceutical compositions containing them
BR9401484A (pt) Hidrazida de ácido 1h-indol-3-acético e formulação farmacêutica
GR3023177T3 (en) Substituted heterocyclic carboxylic acid amide esters, their preparation and their us as medicaments.
NO941361D0 (no) 1H-indol-3-acetamid sPLA2-inhibitorer
KR910000101A (ko) 효소형성 억제제
ATE153334T1 (de) 7-chromanylester von phenolen und benzoesäuren mit retinoidähnlicher aktivität
DE3875750D1 (de) Mikrobizide mittel.
CO5160245A1 (es) Compuestos organicos inhibidores de las proteinasas de cisteina, en particular inhibidores de catepsina k de arilaminoalquilamida, y su uso farmaceutico para el tratamiento o la profilaxis de enfermedades o condiciones medicas en donde este implicada
GB1320181A (en) Cyclic carboxylic acid derivatives
ATE110070T1 (de) Heterocyclisch substituierte chinolylmethoxy- phenylacetamide als lipoxygenasehemmer.
ATE168985T1 (de) Neue antivirale mittel
CA2202966A1 (en) Mixtures of carboxylic acid salts and carboxylic acid esters and their use as siccatives for oxidatively drying lacquers
ES398802A1 (es) Procedimiento para la preparacion de acidos propionicos sustituidos por fenilo en la posicion 2.
IL134787A0 (en) Acid addition salts of morphine alkaloids and compositions containing the same
GB1111361A (en) 4-phenoxyalkanoic acids and derivatives thereof
KR910004652A (ko) 5-α-환원 효소억제제로서의 3-치환된 니트로-스테로이드 유도체
DE69203164D1 (de) Vorbeugende/therapeutische Zusammensetzung für die Pleuropneumonie des Schweins.
ATE222583T1 (de) Derivate substituierter amidinonaphthylester
DE69106888D1 (de) Metallcarboxylate.
UA42830C2 (uk) Засіб для профілактики або лікування рестенозу, фармацевтичний препарат для лікування рестенозу, спосіб профілактики або лікування рестенозу
KR900009533A (ko) 아릴아세트산 모노 에스테르 및 그의 제조방법
ATE347545T1 (de) Hydroxyfunktionelle amid-1h-indolderivate aktiv als spla2 inhibitoren
GB1473981A (en) Hydrazino-cephalosporanic acid derivatives
ATE157652T1 (de) Pge1-analoge