IL120095A0 - Icam-4 materials and methods - Google Patents

Icam-4 materials and methods

Info

Publication number
IL120095A0
IL120095A0 IL12009596A IL12009596A IL120095A0 IL 120095 A0 IL120095 A0 IL 120095A0 IL 12009596 A IL12009596 A IL 12009596A IL 12009596 A IL12009596 A IL 12009596A IL 120095 A0 IL120095 A0 IL 120095A0
Authority
IL
Israel
Prior art keywords
icam
materials
methods
disclosed
bind
Prior art date
Application number
IL12009596A
Other languages
English (en)
Original Assignee
Icos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icos Corp filed Critical Icos Corp
Priority to IL14644796A priority Critical patent/IL146447A0/xx
Publication of IL120095A0 publication Critical patent/IL120095A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00—Modified animals
    • A01K2207/15—Humanized animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/01—Animal expressing industrially exogenous proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Neurosurgery (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Semiconductor Memories (AREA)
  • Treatment And Processing Of Natural Fur Or Leather (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Glass Compositions (AREA)
IL12009596A 1995-06-07 1996-06-06 Icam-4 materials and methods IL120095A0 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL14644796A IL146447A0 (en) 1995-06-07 1996-06-06 Neuron-specific icam-4 promoter

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/481,130 US5702917A (en) 1992-01-27 1995-06-07 Polynucleotides encoding human ICAM-4
PCT/US1996/009146 WO1996040916A1 (en) 1995-06-07 1996-06-06 Icam-4 materials and methods

Publications (1)

Publication Number Publication Date
IL120095A0 true IL120095A0 (en) 1997-04-15

Family

ID=23910735

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14644796A IL146447A0 (en) 1995-06-07 1996-06-06 Neuron-specific icam-4 promoter
IL12009596A IL120095A0 (en) 1995-06-07 1996-06-06 Icam-4 materials and methods

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL14644796A IL146447A0 (en) 1995-06-07 1996-06-06 Neuron-specific icam-4 promoter

Country Status (21)

Country Link
US (1) US5702917A (xx)
EP (2) EP0789763B1 (xx)
JP (2) JP3349514B2 (xx)
CN (2) CN1597950A (xx)
AT (1) ATE224448T1 (xx)
AU (1) AU721316B2 (xx)
BR (1) BR9606440A (xx)
CA (2) CA2288401A1 (xx)
CZ (1) CZ291974B6 (xx)
DE (1) DE69623746T2 (xx)
DK (1) DK0789763T3 (xx)
ES (1) ES2183961T3 (xx)
FI (1) FI970503A (xx)
HU (1) HUP9901123A3 (xx)
IL (2) IL146447A0 (xx)
MX (1) MX9700941A (xx)
NO (1) NO317150B1 (xx)
PL (2) PL188878B1 (xx)
RU (2) RU2155345C2 (xx)
SK (1) SK284161B6 (xx)
WO (1) WO1996040916A1 (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5702917A (en) * 1992-01-27 1997-12-30 Icos Corporation Polynucleotides encoding human ICAM-4
GB9715164D0 (en) * 1997-07-19 1997-09-24 Medical Res Council Improvements in or relating to expression of nucleic acid sequences in cerebellar cells
JP2001508181A (ja) * 1997-10-02 2001-06-19 アイコス コーポレイション Ｉｃａｍ−４及びその診断用途
JP2001506139A (ja) * 1997-10-22 2001-05-15 アイコス コーポレイション Ｉｃａｍ−６物質及び方法
TR200101538T2 (tr) * 1998-11-30 2001-12-21 Ivf Sciences Colorado, Inc. In vitro dölleme sistemi ve sıralı kültür ortamı.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0289949B1 (en) * 1987-05-04 1995-10-04 Dana Farber Cancer Institute Intercellular adhesion molecules, and their binding ligands
PT88641B (pt) * 1987-10-02 1993-04-30 Genentech Inc Metodo para a preparacao de uma variante de adesao
US5272263A (en) * 1989-04-28 1993-12-21 Biogen, Inc. DNA sequences encoding vascular cell adhesion molecules (VCAMS)
US5264554A (en) * 1990-01-19 1993-11-23 The Blood Center Of Southeastern Wisconsin, Inc. Platelet cell adhesion molecule and variants thereof
GB9009548D0 (en) * 1990-04-27 1990-06-20 Celltech Ltd Chimeric antibody and method
DK0468257T3 (da) * 1990-07-20 2000-03-27 Bayer Ag Multimer form af human rhinovirusreceptorprotein
DK0546076T3 (da) * 1990-08-31 1998-10-19 Boehringer Ingelheim Pharma Anvendelse af anti-ICAM antistoffer til fremstilling af et lægemiddel til behandling af endotoksiskshock
WO1992022323A1 (en) * 1991-06-11 1992-12-23 Center For Blood Research, Inc. Intercellular adhesion molecule-3 and its binding ligands
JP3616090B2 (ja) * 1992-01-27 2005-02-02 イコス コーポレイション 細胞間接着分子関連タンパク質
US5702917A (en) * 1992-01-27 1997-12-30 Icos Corporation Polynucleotides encoding human ICAM-4

Also Published As

Publication number Publication date
ATE224448T1 (de) 2002-10-15
NO970546L (no) 1997-04-07
CA2196431A1 (en) 1996-12-19
RU2155345C2 (ru) 2000-08-27
PL318545A1 (en) 1997-06-23
JPH10505508A (ja) 1998-06-02
SK16597A3 (en) 1998-02-04
HUP9901123A3 (en) 2001-10-29
US5702917A (en) 1997-12-30
AU721316B2 (en) 2000-06-29
MX9700941A (es) 1998-01-31
JP3349514B2 (ja) 2002-11-25
CZ291974B6 (cs) 2003-06-18
EP0789763A1 (en) 1997-08-20
CN1597950A (zh) 2005-03-23
DK0789763T3 (da) 2003-01-27
DE69623746D1 (de) 2002-10-24
RU2000111744A (ru) 2002-09-10
DE69623746T2 (de) 2003-05-08
CA2196431C (en) 2000-08-15
FI970503A (fi) 1997-04-04
IL146447A0 (en) 2002-07-25
EP1308514A3 (en) 2004-01-02
HUP9901123A2 (hu) 1999-07-28
PL188878B1 (pl) 2005-05-31
EP0789763B1 (en) 2002-09-18
JP2003047493A (ja) 2003-02-18
CN1164870A (zh) 1997-11-12
PL188612B1 (pl) 2005-03-31
EP1308514A2 (en) 2003-05-07
NO317150B1 (no) 2004-08-30
AU6256096A (en) 1996-12-30
CN1152960C (zh) 2004-06-09
WO1996040916A1 (en) 1996-12-19
ES2183961T3 (es) 2003-04-01
NO970546D0 (no) 1997-02-06
FI970503A0 (fi) 1997-02-06
CA2288401A1 (en) 1996-12-19
BR9606440A (pt) 1997-09-30
SK284161B6 (sk) 2004-10-05
CZ29297A3 (en) 1997-10-15

Similar Documents

Publication Publication Date Title
EP0281604A4 (en) BINDING MOLECULES WITH SINGLE POLYPEPTIDE CHAIN.
FI102768B1 (fi) Hybridi-DNA-molekyyli ja menetelmä fibronektiiniä sitovan proteiinin valmistamiseksi
CA2128208A1 (en) Novel seven transmembrane receptors
FI103049B1 (fi) Hybridi-DNA-molekyyli, tällä molekyylillä transformoitu mikro-organismi ja menetelmä fibronektiiniä sitovan proteiinin valmistamiseksi
GB8826451D0 (en) Improvements in/relating to organic compounds
JPS6420094A (en) Production and purification of protein fused to binding protein
IL120095A0 (en) Icam-4 materials and methods
EP0546087A4 (xx)
EP0317627A4 (en) Oncogene-encoded polypeptide having growth factor activity and methods of production and use thereof
EP0643728A4 (en) PROTEIN RELATED TO INTERCELLULAR ADHESION MOLECULES.
WO1997003089A3 (en) Method for the preparation of insulin by cleavage of a fusion protein and fusion proteins containing insulin a and b chains
EP0237676A3 (en) Recombinant ricin toxin
GB9209804D0 (en) Novel immunoglobulin binding proteins process for their production and recombinant dna molecules coding therefor
SE8403929D0 (sv) Recombinant dna molecule, transformed microorganisms and process for producing penicillin v amidase
GB9226928D0 (en) Novel immunoglobulin binding proteins,process for their production & recombinant dna molecules coding therefor
MX9606653A (es) Endopeptidasa de prolilo estable al calor.