IL114765A - Compositions based on a synergistic mixture of at least one ligand specific for RXRs and at least one ligand specific for RAR-alpha and their uses - Google Patents
Compositions based on a synergistic mixture of at least one ligand specific for RXRs and at least one ligand specific for RAR-alpha and their usesInfo
- Publication number
- IL114765A IL114765A IL11476595A IL11476595A IL114765A IL 114765 A IL114765 A IL 114765A IL 11476595 A IL11476595 A IL 11476595A IL 11476595 A IL11476595 A IL 11476595A IL 114765 A IL114765 A IL 114765A
- Authority
- IL
- Israel
- Prior art keywords
- ligand specific
- alpha
- rar
- rxrs
- compositions based
- Prior art date
Links
- 239000003446 ligand Substances 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title 2
- 102100023606 Retinoic acid receptor alpha Human genes 0.000 title 1
- 102000034527 Retinoid X Receptors Human genes 0.000 title 1
- 108010038912 Retinoid X Receptors Proteins 0.000 title 1
- 238000001403 relative X-ray reflectometry Methods 0.000 title 1
- 108091008726 retinoic acid receptors α Proteins 0.000 title 1
- 230000002195 synergetic effect Effects 0.000 title 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 102000003702 retinoic acid receptors Human genes 0.000 abstract 1
- 108090000064 retinoic acid receptors Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Materials For Medical Uses (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9409307A FR2722985B1 (fr) | 1994-07-27 | 1994-07-27 | Nouvelles compositions a base d'un melange synergetique entre au moins un ligand specifique des rxrs et au moins un ligand specifique de rar-x ou de vdr, et leurs utilisations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL114765A0 IL114765A0 (en) | 1995-11-27 |
| IL114765A true IL114765A (en) | 2000-06-01 |
Family
ID=9465802
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11476595A IL114765A (en) | 1994-07-27 | 1995-07-27 | Compositions based on a synergistic mixture of at least one ligand specific for RXRs and at least one ligand specific for RAR-alpha and their uses |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5767148A (xx) |
| EP (1) | EP0694301B1 (xx) |
| JP (1) | JP2783521B2 (xx) |
| KR (1) | KR0168727B1 (xx) |
| AT (1) | ATE145134T1 (xx) |
| AU (1) | AU674479B2 (xx) |
| BR (1) | BR9502338A (xx) |
| CA (1) | CA2154730C (xx) |
| DE (1) | DE69500085T2 (xx) |
| ES (1) | ES2098164T3 (xx) |
| FI (1) | FI953567A (xx) |
| FR (1) | FR2722985B1 (xx) |
| HU (1) | HUT73793A (xx) |
| IL (1) | IL114765A (xx) |
| NO (1) | NO952944L (xx) |
| NZ (1) | NZ272527A (xx) |
| PL (1) | PL181061B1 (xx) |
| RU (1) | RU2120304C1 (xx) |
| ZA (1) | ZA955537B (xx) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2735370B1 (fr) * | 1995-06-19 | 1997-07-18 | Cird Galderma | Procede pour identifier des composes agonistes des recepteurs rxrs |
| FR2735367B1 (fr) * | 1995-06-19 | 1997-07-18 | Cird Galderma | Utilisation de ligands specifiques des recepteurs rxrs |
| FR2739777B1 (fr) * | 1995-10-11 | 1997-11-14 | Cird Galderma | Ligand antagoniste rar-gamma ou agoniste rar-alpha en tant qu'inhibiteur d'apoptose |
| FR2753091B1 (fr) * | 1996-09-09 | 2001-03-16 | Oreal | Utilisation d'un agoniste des recepteurs des retinoides de type rxr pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute |
| JP2001522350A (ja) * | 1997-04-11 | 2001-11-13 | シドニー キメル キャンサー センター | 疾患におけるエンドセリン−１の過剰産生の阻害のためのレチノイド関連分子 |
| CA2295807A1 (en) * | 1997-07-29 | 1999-02-11 | Bristol-Myers Squibb Company | Use of selective rxr agonists to prevent surgical adhesions |
| FR2779720B1 (fr) * | 1998-06-12 | 2002-08-16 | Galderma Rech Dermatologique | Nouveaux composes diarylselenures et leur utilisation en medecine humaine ou veterinaire ainsi qu'en cosmetologie |
| US6436993B1 (en) * | 1999-07-13 | 2002-08-20 | The Salk Institute For Biological Studies | Use of RAR antagonists as modulators of hormone mediated processes |
| US6904229B1 (en) * | 1999-08-20 | 2005-06-07 | Canon Kabushiki Kaisha | Apparatus for recording signals on disk recording medium |
| CN100388532C (zh) * | 2005-09-28 | 2008-05-14 | 浙江工业大学 | 一种锂二次电池的隔膜添加剂及锂二次电池隔膜 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0600028B1 (en) * | 1991-08-23 | 2001-11-07 | The Salk Institute For Biological Studies | Use of selective ligands for treatment of disease states responsive to steroid or steroid-like hormones |
| ATE256653T1 (de) * | 1992-04-22 | 2004-01-15 | Ligand Pharm Inc | Verbindungen mit retinoid x receptorselektivität |
-
1994
- 1994-07-27 FR FR9409307A patent/FR2722985B1/fr not_active Expired - Fee Related
-
1995
- 1995-06-21 EP EP95401477A patent/EP0694301B1/fr not_active Expired - Lifetime
- 1995-06-21 ES ES95401477T patent/ES2098164T3/es not_active Expired - Lifetime
- 1995-06-21 AT AT95401477T patent/ATE145134T1/de not_active IP Right Cessation
- 1995-06-21 DE DE69500085T patent/DE69500085T2/de not_active Expired - Fee Related
- 1995-06-27 AU AU23279/95A patent/AU674479B2/en not_active Ceased
- 1995-07-04 ZA ZA955537A patent/ZA955537B/xx unknown
- 1995-07-07 NZ NZ272527A patent/NZ272527A/en unknown
- 1995-07-12 BR BR9502338A patent/BR9502338A/pt active Search and Examination
- 1995-07-21 JP JP7185956A patent/JP2783521B2/ja not_active Expired - Fee Related
- 1995-07-25 KR KR1019950022143A patent/KR0168727B1/ko not_active IP Right Cessation
- 1995-07-25 NO NO952944A patent/NO952944L/no not_active Application Discontinuation
- 1995-07-26 HU HU9502241A patent/HUT73793A/hu unknown
- 1995-07-26 RU RU95113115A patent/RU2120304C1/ru not_active IP Right Cessation
- 1995-07-26 FI FI953567A patent/FI953567A/fi not_active IP Right Cessation
- 1995-07-26 CA CA002154730A patent/CA2154730C/fr not_active Expired - Fee Related
- 1995-07-26 PL PL95309772A patent/PL181061B1/pl not_active IP Right Cessation
- 1995-07-27 IL IL11476595A patent/IL114765A/xx not_active IP Right Cessation
- 1995-07-27 US US08/507,913 patent/US5767148A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0694301B1 (fr) | 1996-11-13 |
| ES2098164T3 (es) | 1997-04-16 |
| ZA955537B (en) | 1996-02-16 |
| KR960003721A (ko) | 1996-02-23 |
| PL309772A1 (en) | 1996-02-05 |
| NZ272527A (en) | 1997-01-29 |
| ATE145134T1 (de) | 1996-11-15 |
| JP2783521B2 (ja) | 1998-08-06 |
| AU674479B2 (en) | 1996-12-19 |
| IL114765A0 (en) | 1995-11-27 |
| FR2722985B1 (fr) | 1996-09-13 |
| DE69500085T2 (de) | 1997-03-06 |
| RU2120304C1 (ru) | 1998-10-20 |
| DE69500085D1 (de) | 1996-12-19 |
| FI953567A0 (fi) | 1995-07-26 |
| AU2327995A (en) | 1996-02-08 |
| HUT73793A (en) | 1996-09-30 |
| NO952944D0 (no) | 1995-07-25 |
| BR9502338A (pt) | 1996-02-27 |
| HU9502241D0 (en) | 1995-09-28 |
| FI953567A (fi) | 1996-01-28 |
| NO952944L (no) | 1996-01-29 |
| JPH0859511A (ja) | 1996-03-05 |
| KR0168727B1 (ko) | 1999-01-15 |
| CA2154730A1 (fr) | 1996-01-28 |
| EP0694301A1 (fr) | 1996-01-31 |
| US5767148A (en) | 1998-06-16 |
| CA2154730C (fr) | 2000-02-15 |
| PL181061B1 (pl) | 2001-05-31 |
| FR2722985A1 (fr) | 1996-02-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |