IL114697A0 - Polypeptides comprising ubiquitin-lytic peptide fusion protein products deriving therefrom their preparation and use - Google Patents

Polypeptides comprising ubiquitin-lytic peptide fusion protein products deriving therefrom their preparation and use

Info

Publication number
IL114697A0
IL114697A0 IL11469795A IL11469795A IL114697A0 IL 114697 A0 IL114697 A0 IL 114697A0 IL 11469795 A IL11469795 A IL 11469795A IL 11469795 A IL11469795 A IL 11469795A IL 114697 A0 IL114697 A0 IL 114697A0
Authority
IL
Israel
Prior art keywords
ubiquitin
polypeptides
preparation
fusion protein
protein products
Prior art date
Application number
IL11469795A
Other languages
English (en)
Original Assignee
Demeter Biotech Ltd
Us Agriculture
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Demeter Biotech Ltd, Us Agriculture filed Critical Demeter Biotech Ltd
Publication of IL114697A0 publication Critical patent/IL114697A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8222—Developmentally regulated expression systems, tissue, organ specific, temporal or spatial regulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8237—Externally regulated expression systems
    • C12N15/8239—Externally regulated expression systems pathogen inducible
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL11469795A 1994-07-22 1995-07-23 Polypeptides comprising ubiquitin-lytic peptide fusion protein products deriving therefrom their preparation and use IL114697A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27947294A 1994-07-22 1994-07-22

Publications (1)

Publication Number Publication Date
IL114697A0 true IL114697A0 (en) 1995-11-27

Family

ID=23069116

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11469795A IL114697A0 (en) 1994-07-22 1995-07-23 Polypeptides comprising ubiquitin-lytic peptide fusion protein products deriving therefrom their preparation and use

Country Status (7)

Country Link
US (1) US6448391B1 (fr)
EP (1) EP0781347A4 (fr)
JP (1) JPH10507069A (fr)
AU (2) AU3199695A (fr)
CA (1) CA2195625C (fr)
IL (1) IL114697A0 (fr)
WO (2) WO1996003522A1 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0932413A1 (fr) 1996-10-04 1999-08-04 Demegen, Inc. Procede de traitement d'une contamination par le virus de l'immunodeficience
US6121436A (en) 1996-12-13 2000-09-19 Monsanto Company Antifungal polypeptide and methods for controlling plant pathogenic fungi
US6635740B1 (en) 1997-03-27 2003-10-21 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Ligand/lytic peptide compositions and methods of use
AU6587998A (en) * 1997-03-27 1998-10-20 Demeter Biotechnologies, Ltd. Ligand/lytic peptide compositions and methods of use
EP1878438B1 (fr) * 1997-03-27 2017-11-29 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Compositions de peptide ligand/lytique et procédés d'utilisation
FR2766207B1 (fr) * 1997-07-11 2000-12-08 Rhone Poulenc Agrochimie Gene chimere codant pour la drosomycine, vecteur le contenant pour la transformation des cellules vegetales et plantes transformees obtenues resistantes aux maladies
FR2766206A1 (fr) * 1997-07-11 1999-01-22 Rhone Poulenc Agrochimie Gene chimere codant pour la drosomycine, vecteur le contenant pour la transformation des cellules vegetales et plantes transformees obtenues resistantes aux maladies
US6680058B1 (en) 1997-09-03 2004-01-20 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Compositions and methods for contraception in or sterilization of mammals
KR19990081420A (ko) * 1998-04-29 1999-11-15 성재갑 효모 2 하이브리드 시스템으로 검색할 수 있는 유비퀴틴을 이용한 펩타이드 라이브러리 및 그의 제조방법
US7087811B1 (en) 1998-12-11 2006-08-08 Agency For Science, Technology And Research Enhanced protein production in higher plants by N-terminal fusion of a ubiquitin or a cucumber mosaic virus coat protein peptide
US6875744B2 (en) 2001-03-28 2005-04-05 Helix Biomedix, Inc. Short bioactive peptides
JP4310107B2 (ja) * 2001-03-28 2009-08-05 ヘリックス バイオメディックス，インコーポレイテッド 生物活性を有する短ペプチド及び該ペプチドの使用方法
DE10201862A1 (de) 2002-01-18 2003-08-07 Deutsches Krebsforsch Konjugat zur Behandlung prokaryontischer Infektionen
US20050034188A1 (en) * 2002-03-20 2005-02-10 J. R. Simplot Company Refined plant transformation
CA2479739C (fr) * 2002-03-20 2013-02-19 J.R. Simplot Company Transformation raffinee des plantes
CN1894277A (zh) * 2003-02-24 2007-01-10 陶氏环球技术公司 周期性抗微生物肽
US7091185B2 (en) * 2003-02-24 2006-08-15 Dow Global Technologies Inc. Periodic antimicrobial peptides
EP1853620B1 (fr) 2005-02-09 2012-01-11 Helix Biomedix, Inc. Hexapeptides antimicrobiens
TW200700076A (en) * 2005-03-18 2007-01-01 Novozymes As Polypeptides having antimicrobial activity and polynucleotides encoding same
US7534762B2 (en) 2005-03-18 2009-05-19 Novozymes A/S Polypeptides having antimicrobial activity and polynucleotides encoding same
DK2252627T3 (en) 2008-01-24 2017-08-14 Esperance Pharmaceuticals MERGER CONSTRUCTION WITH LYTIC DOMAIN AND METHOD FOR PRODUCING AND USING SAME.
EP2168591A1 (fr) * 2008-09-24 2010-03-31 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Peptides antimicrobiens
JP2015532114A (ja) * 2012-10-20 2015-11-09 セルフダイアグノスティックス オーウー 生物学的サンプル及び体液に由来する核酸標的の検出のための方法及びその組成物
WO2014070957A1 (fr) 2012-10-30 2014-05-08 Esperance Pharmaceuticals, Inc. Conjugués anticorps/médicament et leurs procédés d'utilisation
JP5918295B2 (ja) * 2014-04-14 2016-05-18 佛教慈濟醫療財團法人大林慈濟醫院 融合蛋白質、その製造方法、及び融合蛋白質により抗原ペプチドを小胞体に輸送する方法
US10016480B2 (en) * 2014-10-14 2018-07-10 The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services Peptide-based methods for treating pancreatic cancer
CN107614004B (zh) * 2015-03-23 2022-12-06 激流生物科学有限公司 抗微生物肽及其使用方法
US10413584B1 (en) 2018-08-29 2019-09-17 Riptide Bioscience, Inc. Peptides having immunomodulatory properties
US10548944B1 (en) 2018-10-19 2020-02-04 Riptide Bioscience, Inc. Antimicrobial peptides and methods of using the same

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4520016A (en) 1980-06-17 1985-05-28 Kabigen Ab Bacteriolytic proteins
US4355104A (en) 1980-06-17 1982-10-19 Kabigen Ab Bacteriolytic proteins
WO1986004356A1 (fr) * 1985-01-28 1986-07-31 International Genetic Engineering, Inc. PROMOTEURS D'araB ET PROCEDE DE PRODUCTION DE POLYPEPTIDES, Y COMPRIS DES CECROPINES, PAR DES TECHNIQUES MICROBIOLOGIQUES
US5028530A (en) 1985-01-28 1991-07-02 Xoma Corporation AraB promoters and method of producing polypeptides, including cecropins, by microbiological techniques
US5196321A (en) 1986-10-02 1993-03-23 Massachusetts Institute Of Technology Methods for in vitro cleavage of ubiquitin fusion proteins
US5093242A (en) 1986-10-02 1992-03-03 Massachusetts Institute Of Technology Methods of generating desired amino-terminal residues in proteins
US5132213A (en) 1986-10-02 1992-07-21 Massachusetts Institute Of Technology Method for producing proteins and polypeptides using ubiquitin fusions
US4810777A (en) 1987-03-04 1989-03-07 The United States Of America As Represented By The Department Of Health And Human Services Antimicrobial compounds
EP0675960A1 (fr) * 1987-11-02 1995-10-11 Louisiana State University and Agricultural and Mechanical College Plantes ameliorees genetiquement pour resister aux maladies
ES2060765T3 (es) * 1988-05-17 1994-12-01 Lubrizol Genetics Inc Sistema promotor de ubiquitina en plantas.
DE69034085T2 (de) * 1989-04-10 2004-05-27 Helix BioMedix, Inc., Bothell Lytsche und proliferative Peptide und deren Verwendung als Pharmaka und Phytopharmaka
CA2030779A1 (fr) * 1989-04-11 1990-10-12 Huw M. Davies Utilisation de peptides antimicrobiens d'origine animale pour lutter contre les agents pathogenes des plantes
US5620923A (en) * 1989-10-12 1997-04-15 The University Of Utah Synthesis of peptides as cloned ubiquitin extensions
US5294605A (en) 1990-07-19 1994-03-15 The Scripps Research Institute Amphiphilic peptide compositions and analogues thereof
GB9127250D0 (en) 1991-12-23 1992-02-19 Unilever Plc Modification
DE69332740T2 (de) * 1992-08-21 2004-02-05 The University Of British Columbia, Vancouver Kationische peptide und verfahren zu deren herstellung
US5773705A (en) * 1992-12-31 1998-06-30 Wisconsin Alumni Research Foundation Ubiquitin fusion protein system for protein production in plants
GB9300281D0 (en) * 1993-01-08 1993-03-03 Zeneca Ltd Antimicrobial-protein-producing endosymbiotic micro-organisms
AU6290496A (en) * 1995-06-27 1997-01-30 Igen International, Inc. High-level expression and efficient recovery of ubiquitin fusion proteins from escherichia coli

Also Published As

Publication number Publication date
EP0781347A4 (fr) 2000-03-22
CA2195625A1 (fr) 1996-02-08
US6448391B1 (en) 2002-09-10
AU3199695A (en) 1996-02-22
CA2195625C (fr) 2000-10-10
JPH10507069A (ja) 1998-07-14
WO1996003519A1 (fr) 1996-02-08
EP0781347A1 (fr) 1997-07-02
WO1996003522A1 (fr) 1996-02-08
AU3199595A (en) 1996-02-22

Similar Documents

Publication Publication Date Title
IL114697A0 (en) Polypeptides comprising ubiquitin-lytic peptide fusion protein products deriving therefrom their preparation and use
PL320824A1 (en) Aerodol form of a preparation of peptides and proteins
EP0785276A4 (fr) Modification d'un peptide et d'une proteine
EP0799577A4 (fr) Melange de peptides et leurs produits
IL113708A0 (en) Protein production and protein delivery
HUP0000302A3 (en) Ob fusion protein compositions and methods
EP0704532A3 (fr) Protéines chimériques recombinantes et procédés pour leur utilisation
AU6428890A (en) Therapeutic peptides and proteins
EP0939761A4 (fr) Proteines secretees par la salmonelle et utilisations de ces proteines
IL112075A0 (en) Recombinant human thymopoietin proteins, their preparation and their medicinal use
ZA96240B (en) Novel peptides their preparation and use
HU9502114D0 (en) Expression system using autolysable fusion protein and new reducing polypeptides
SG52708A1 (en) Chimeric receptor polypeptides human h13 proteins and uses thereof
IL116658A0 (en) Peptides their preparation and use
IL110954A (en) Pharmaceutical compositions comprising a retinoblastoma polypeptide or protein and methods for the preparation and use thereof
GB9423372D0 (en) Proteins and their uses
IL114356A0 (en) A human fibroblast derived protein and its preparation
GB2336844B (en) Anti-hiv peptides and proteins
ZA983622B (en) Protein composition preparation and use thereof and products containing same and preparation thereof
ZA978220B (en) PTX-sensitive G proteins their preparation and use
EP0540575A4 (en) Human meg-csf protein and methods
IL116976A0 (en) Synthetic peptides and pharmaceutical compositions comprising them
EP0857732A4 (fr) Proteine humaine analogue a la pec-60 et adn qui la code
AUPM832694A0 (en) Peptides and polypeptides
IL112094A0 (en) Novel peptides and pharmaceutical compositions comprising them