IL114666A - Influenza virus subunit conjugates - Google Patents

Influenza virus subunit conjugates

Info

Publication number
IL114666A
IL114666A IL11466695A IL11466695A IL114666A IL 114666 A IL114666 A IL 114666A IL 11466695 A IL11466695 A IL 11466695A IL 11466695 A IL11466695 A IL 11466695A IL 114666 A IL114666 A IL 114666A
Authority
IL
Israel
Prior art keywords
protein
influenza virus
conjugates
influenza
procedure
Prior art date
Application number
IL11466695A
Other languages
English (en)
Other versions
IL114666A0 (en
Inventor
Robert C Huebner
Maurice W Harmon
Original Assignee
Connaught Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Connaught Lab filed Critical Connaught Lab
Publication of IL114666A0 publication Critical patent/IL114666A0/xx
Publication of IL114666A publication Critical patent/IL114666A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6075—Viral proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6087—Polysaccharides; Lipopolysaccharides [LPS]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL11466695A 1994-07-26 1995-07-19 Influenza virus subunit conjugates IL114666A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/280,463 US5612037A (en) 1994-07-26 1994-07-26 Influenza virus subunit conjugates

Publications (2)

Publication Number Publication Date
IL114666A0 IL114666A0 (en) 1995-11-27
IL114666A true IL114666A (en) 1999-12-22

Family

ID=23073201

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11466695A IL114666A (en) 1994-07-26 1995-07-19 Influenza virus subunit conjugates

Country Status (12)

Country Link
US (1) US5612037A (ja)
EP (1) EP0810876B1 (ja)
JP (1) JP4024849B2 (ja)
AT (1) ATE394120T1 (ja)
AU (1) AU707143B2 (ja)
CA (1) CA2194183A1 (ja)
DE (1) DE69535750D1 (ja)
FI (1) FI970277A0 (ja)
IL (1) IL114666A (ja)
NO (1) NO319525B1 (ja)
WO (1) WO1996003145A1 (ja)
ZA (1) ZA955945B (ja)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000035481A2 (en) 1998-12-17 2000-06-22 Connaught Laboratories Limited Multivalent immunogenic composition containing rsv subunit composition and influenza virus preparation
US8106098B2 (en) * 1999-08-09 2012-01-31 The General Hospital Corporation Protein conjugates with a water-soluble biocompatible, biodegradable polymer
WO2002026252A1 (fr) * 2000-08-10 2002-04-04 Tsinghua University Vaccin contre le virus de la grippe et son procede de preparation
US7838619B2 (en) * 2002-01-14 2010-11-23 The General Hospital Corporation Biodegradable polyketal polymers and methods for their formation and use
JP4800614B2 (ja) * 2002-07-19 2011-10-26 ザ ジェネラル ホスピタル コーポレイション オキシム結合体、およびそれらの形成および使用のための方法
RU2005131016A (ru) * 2003-03-07 2006-06-10 Мерк энд Ко., Инк. (US) Вакцина вируса гриппа
DE602004032553D1 (de) 2003-09-05 2011-06-16 Gen Hospital Corp Polyacetal-arzneimittelkonjugate als freisetzungssystem
US20060190188A1 (en) * 2005-01-25 2006-08-24 Nauta Jozef J Methods and systems for determining lot consistency
CA2552596A1 (en) * 2005-08-09 2007-02-09 Solvay Pharmaceuticals B.V. Methods and systems for determining mid-value titers
ES2534332T3 (es) * 2006-03-07 2015-04-21 Vaxinnate Corporation Composiciones que incluyen hemaglutinina, métodos de preparación y métodos de uso de las mismas
EP2772267B1 (en) * 2007-08-27 2016-04-27 Longhorn Vaccines and Diagnostics, LLC Immunogenic compositions and methods
US10004799B2 (en) 2007-08-27 2018-06-26 Longhorn Vaccines And Diagnostics, Llc Composite antigenic sequences and vaccines
WO2009128950A2 (en) * 2008-04-18 2009-10-22 Vaxinnate Corporation Deletion mutants of flagellin and methods of use
KR20110102420A (ko) * 2008-12-10 2011-09-16 메르사나 테라퓨틱스, 인코포레이티드 생분해성 및 생체적합성 캄토테신-중합체 접합체의 약학 제제
WO2010144797A2 (en) 2009-06-12 2010-12-16 Vaccine Technologies, Incorporated Influenza vaccines with enhanced immunogenicity and uses thereof
US20130115237A1 (en) 2010-06-09 2013-05-09 Vaccine Technologies, Incorporated Therapeutic immunization in hiv infected subjects to augment antiretroviral treatment
US8932598B2 (en) 2012-08-28 2015-01-13 Vaxinnate Corporation Fusion proteins and methods of use
KR102094727B1 (ko) 2012-10-05 2020-03-30 덴카 세이켄 가부시키가이샤 인플루엔자 바이러스의 헤마글루티닌 측정 방법
JP6426103B2 (ja) * 2013-10-15 2018-11-21 国立大学法人 東京大学 ｃ−Ｍｅｔタンパク質アゴニスト

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4762913A (en) * 1973-05-07 1988-08-09 The Ohio State University Antigenic modification of polypeptides
EP0270295A3 (en) * 1986-12-03 1989-08-02 Connaught Laboratories Limited Conjugate vaccine
US5354554A (en) * 1989-02-10 1994-10-11 Celltech Limited Crosslinked antibodies and processes for their preparation
NZ240369A (en) * 1990-10-30 1993-09-27 Daiichi Seiyaku Co Muramyl dipeptide derivatives and vaccine compositions

Also Published As

Publication number Publication date
NO970080D0 (no) 1997-01-09
EP0810876B1 (en) 2008-05-07
EP0810876A1 (en) 1997-12-10
ZA955945B (en) 1996-02-21
FI970277A (fi) 1997-01-23
JPH10503494A (ja) 1998-03-31
US5612037A (en) 1997-03-18
NO970080L (no) 1997-01-09
FI970277A0 (fi) 1997-01-23
EP0810876A4 (en) 2002-10-23
ATE394120T1 (de) 2008-05-15
CA2194183A1 (en) 1996-02-08
JP4024849B2 (ja) 2007-12-19
NO319525B1 (no) 2005-08-22
DE69535750D1 (de) 2008-06-19
IL114666A0 (en) 1995-11-27
WO1996003145A1 (en) 1996-02-08
AU3234295A (en) 1996-02-22
AU707143B2 (en) 1999-07-01

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Legal Events

Date Code Title Description
FF Patent granted
NE Application for restoration - patent lapsed through non-payment of renewal fees (section 60, patents law, 5727-1967)
KB Patent renewed