FI970277A - Influenssavirusalayksikön konjugaatteja - Google Patents

Influenssavirusalayksikön konjugaatteja Download PDF

Info

Publication number
FI970277A
FI970277A FI970277A FI970277A FI970277A FI 970277 A FI970277 A FI 970277A FI 970277 A FI970277 A FI 970277A FI 970277 A FI970277 A FI 970277A FI 970277 A FI970277 A FI 970277A
Authority
FI
Finland
Prior art keywords
protein
influenza virus
conjugates
influenza
procedure
Prior art date
Application number
FI970277A
Other languages
English (en)
Swedish (sv)
Other versions
FI970277A0 (fi
Inventor
Robert C Huebner
Maurice W Harmon
Original Assignee
Connaught Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Connaught Lab filed Critical Connaught Lab
Publication of FI970277A publication Critical patent/FI970277A/fi
Publication of FI970277A0 publication Critical patent/FI970277A0/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6037Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6075Viral proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6087Polysaccharides; Lipopolysaccharides [LPS]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/62Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/627Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI970277A 1994-07-26 1997-01-23 Influenssavirusalayksikön konjugaatteja FI970277A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/280,463 US5612037A (en) 1994-07-26 1994-07-26 Influenza virus subunit conjugates
PCT/US1995/009235 WO1996003145A1 (en) 1994-07-26 1995-07-20 Influenza virus subunit conjugates

Publications (2)

Publication Number Publication Date
FI970277A true FI970277A (fi) 1997-01-23
FI970277A0 FI970277A0 (fi) 1997-01-23

Family

ID=23073201

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970277A FI970277A0 (fi) 1994-07-26 1997-01-23 Influenssavirusalayksikön konjugaatteja

Country Status (12)

Country Link
US (1) US5612037A (fi)
EP (1) EP0810876B1 (fi)
JP (1) JP4024849B2 (fi)
AT (1) ATE394120T1 (fi)
AU (1) AU707143B2 (fi)
CA (1) CA2194183A1 (fi)
DE (1) DE69535750D1 (fi)
FI (1) FI970277A0 (fi)
IL (1) IL114666A (fi)
NO (1) NO319525B1 (fi)
WO (1) WO1996003145A1 (fi)
ZA (1) ZA955945B (fi)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000035481A2 (en) 1998-12-17 2000-06-22 Connaught Laboratories Limited Multivalent immunogenic composition containing rsv subunit composition and influenza virus preparation
US8106098B2 (en) * 1999-08-09 2012-01-31 The General Hospital Corporation Protein conjugates with a water-soluble biocompatible, biodegradable polymer
WO2002026252A1 (fr) * 2000-08-10 2002-04-04 Tsinghua University Vaccin contre le virus de la grippe et son procede de preparation
US7838619B2 (en) * 2002-01-14 2010-11-23 The General Hospital Corporation Biodegradable polyketal polymers and methods for their formation and use
JP4800614B2 (ja) * 2002-07-19 2011-10-26 ザ ジェネラル ホスピタル コーポレイション オキシム結合体、およびそれらの形成および使用のための方法
RU2005131016A (ru) * 2003-03-07 2006-06-10 Мерк энд Ко., Инк. (US) Вакцина вируса гриппа
DE602004032553D1 (de) 2003-09-05 2011-06-16 Gen Hospital Corp Polyacetal-arzneimittelkonjugate als freisetzungssystem
US20060190188A1 (en) * 2005-01-25 2006-08-24 Nauta Jozef J Methods and systems for determining lot consistency
CA2552596A1 (en) * 2005-08-09 2007-02-09 Solvay Pharmaceuticals B.V. Methods and systems for determining mid-value titers
ES2534332T3 (es) * 2006-03-07 2015-04-21 Vaxinnate Corporation Composiciones que incluyen hemaglutinina, métodos de preparación y métodos de uso de las mismas
EP2772267B1 (en) * 2007-08-27 2016-04-27 Longhorn Vaccines and Diagnostics, LLC Immunogenic compositions and methods
US10004799B2 (en) 2007-08-27 2018-06-26 Longhorn Vaccines And Diagnostics, Llc Composite antigenic sequences and vaccines
WO2009128950A2 (en) * 2008-04-18 2009-10-22 Vaxinnate Corporation Deletion mutants of flagellin and methods of use
KR20110102420A (ko) * 2008-12-10 2011-09-16 메르사나 테라퓨틱스, 인코포레이티드 생분해성 및 생체적합성 캄토테신-중합체 접합체의 약학 제제
WO2010144797A2 (en) 2009-06-12 2010-12-16 Vaccine Technologies, Incorporated Influenza vaccines with enhanced immunogenicity and uses thereof
US20130115237A1 (en) 2010-06-09 2013-05-09 Vaccine Technologies, Incorporated Therapeutic immunization in hiv infected subjects to augment antiretroviral treatment
US8932598B2 (en) 2012-08-28 2015-01-13 Vaxinnate Corporation Fusion proteins and methods of use
KR102094727B1 (ko) 2012-10-05 2020-03-30 덴카 세이켄 가부시키가이샤 인플루엔자 바이러스의 헤마글루티닌 측정 방법
JP6426103B2 (ja) * 2013-10-15 2018-11-21 国立大学法人 東京大学 c−Metタンパク質アゴニスト

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4762913A (en) * 1973-05-07 1988-08-09 The Ohio State University Antigenic modification of polypeptides
EP0270295A3 (en) * 1986-12-03 1989-08-02 Connaught Laboratories Limited Conjugate vaccine
US5354554A (en) * 1989-02-10 1994-10-11 Celltech Limited Crosslinked antibodies and processes for their preparation
NZ240369A (en) * 1990-10-30 1993-09-27 Daiichi Seiyaku Co Muramyl dipeptide derivatives and vaccine compositions

Also Published As

Publication number Publication date
NO970080D0 (no) 1997-01-09
EP0810876B1 (en) 2008-05-07
EP0810876A1 (en) 1997-12-10
ZA955945B (en) 1996-02-21
JPH10503494A (ja) 1998-03-31
US5612037A (en) 1997-03-18
NO970080L (no) 1997-01-09
FI970277A0 (fi) 1997-01-23
EP0810876A4 (en) 2002-10-23
ATE394120T1 (de) 2008-05-15
CA2194183A1 (en) 1996-02-08
IL114666A (en) 1999-12-22
JP4024849B2 (ja) 2007-12-19
NO319525B1 (no) 2005-08-22
DE69535750D1 (de) 2008-06-19
IL114666A0 (en) 1995-11-27
WO1996003145A1 (en) 1996-02-08
AU3234295A (en) 1996-02-22
AU707143B2 (en) 1999-07-01

Similar Documents

Publication Publication Date Title
FI970277A0 (fi) Influenssavirusalayksikön konjugaatteja
BR9306820A (pt) Conjugado de um antígeno fracamente imunogênico e um veículo peptideo sintetico vacina processos para melhorar a imunogenicidade de uma molecula de antigeno fracamente imunogenico e para imunizar um hospedeiro mamífero
DK0538437T3 (da) Immunstimulerende og immunforstærkende, rekonstituerede influenzavirosomer og vacciner indeholdende dem
ATE258188T1 (de) Retro-, inverso-, und retro-inverso synthetische peptidanaloge
ATE109008T1 (de) T-zellen-epitope als träger für einen konjugierten impfstoff.
ATE557041T1 (de) Peptid-vakzinen gegen streptokokken der gruppe a
IL91007A0 (en) Synthetic vaccine against aids virus
DE60043620D1 (de) Mage-a1 peptide die von klasse ii hla molekule presentiert werden
KR890004730A (ko) G_7rh에 대한 면역반응을 유발시키고 포유동물을 면역 불임시키기 위한 제제 및 방법
BR0314373A (pt) Produto imunogênico estável para a indução de anticorpos contra uma ou várias proteìnas antigênicas em um indivìduo, composições farmacêutica, imunogênica e de vacina e processo de preparação de um produto imunogênico
CO5300414A1 (es) Composiciones de vacunas con antigenos de streptococus de virus vsr y adyuvante estimulador de respuesta th1
ATE302016T1 (de) Peptide, verwendet als träger in immunogenen konstrukten, die in der entwicklung synthetischer impfstoffe geeignet sind
RU2008112497A (ru) Коньюгат для иммунизации и вакцинации и способ повышения иммуногенности
NO920942L (no) Konjugert vaksine for gruppe b streptococcus
DE69928064D1 (de) Mimotopen der hypervariabele region des e2 glykoproteins von hcv und deren verwendungen
BR9709993A (pt) Vacina preparação de vacina composição processo para produção de uma preparação imugênica e preparação imugênica
PT871738E (pt) Particulas virais recombinantes e aplicacoes vacinais e antitumorais
DK421486A (da) Polydisperse native pseudomonas-flagella(h)-antigener (fag) og fremgangsmaade til deres udvinding
WO2002051237A3 (en) Helicobacter proteins, nucleic acids and uses thereof
WO2002051865A3 (fr) Antigenes proteiques inducteurs d'anticorps neutralisant le virus vih
GB2314560A (en) Synthetic peptides of m. gallisepticum, antibodies thereto, their preparations and use
CO5241277A1 (es) Vacuna
ES2065254A1 (es) Peptidos y vacunas sinteticas contra parvovirus canino y otros virus relacionados.
ES1027961U (es) Soporte publicitario para carritos.
TH23870EX (th) วัคซีนและวิธีสำหรับการเตรียม