IL114246A - Method for the purification of the 32-amino isomeric E-32 of compounds LL-94282 - Google Patents

Method for the purification of the 32-amino isomeric E-32 of compounds LL-94282

Info

Publication number
IL114246A
IL114246A IL11424695A IL11424695A IL114246A IL 114246 A IL114246 A IL 114246A IL 11424695 A IL11424695 A IL 11424695A IL 11424695 A IL11424695 A IL 11424695A IL 114246 A IL114246 A IL 114246A
Authority
IL
Israel
Prior art keywords
chloride
compound
carbamoyl
groups
methyl
Prior art date
Application number
IL11424695A
Other languages
English (en)
Hebrew (he)
Other versions
IL114246A0 (en
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of IL114246A0 publication Critical patent/IL114246A0/xx
Publication of IL114246A publication Critical patent/IL114246A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL11424695A 1994-06-22 1995-06-21 Method for the purification of the 32-amino isomeric E-32 of compounds LL-94282 IL114246A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/263,967 US5478951A (en) 1994-06-22 1994-06-22 Method for the purification of 23-E isomers of 23-imino derivatives of LL-F28249 compounds

Publications (2)

Publication Number Publication Date
IL114246A0 IL114246A0 (en) 1995-10-31
IL114246A true IL114246A (en) 1998-10-30

Family

ID=23004003

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11424695A IL114246A (en) 1994-06-22 1995-06-21 Method for the purification of the 32-amino isomeric E-32 of compounds LL-94282

Country Status (20)

Country Link
US (1) US5478951A (de)
EP (1) EP0688775B1 (de)
JP (1) JP3817756B2 (de)
KR (1) KR100367947B1 (de)
CN (1) CN1063445C (de)
AT (1) ATE214071T1 (de)
AU (1) AU681785C (de)
BR (1) BR9502869A (de)
CA (1) CA2152249A1 (de)
CZ (1) CZ288894B6 (de)
DE (1) DE69525686T2 (de)
DK (1) DK0688775T3 (de)
ES (1) ES2172554T3 (de)
HU (1) HU216278B (de)
IL (1) IL114246A (de)
PT (1) PT688775E (de)
SI (1) SI0688775T1 (de)
SK (1) SK283198B6 (de)
TW (1) TW319770B (de)
ZA (1) ZA955106B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7348417B2 (en) * 2003-08-07 2008-03-25 Wyeth Method of purifying moxidectin through crystallization
CN104277050B (zh) * 2013-07-04 2016-05-04 北大方正集团有限公司 一种制备莫西克汀的方法
CN103601735B (zh) * 2013-11-08 2015-12-09 大连九信生物化工科技有限公司 一种提纯莫西克汀的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4916154A (en) * 1986-09-12 1990-04-10 American Cyanamid Company 23-Imino derivatives of LL-F28249 compounds
GB8721377D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical compounds
NZ233680A (en) * 1989-05-17 1995-02-24 Beecham Group Plc Avermectins and milbemycins and compositions thereof
US4988824A (en) * 1989-09-11 1991-01-29 Maulding Donald R Process for the preparation of 23-(C1-C6 alkyloxime)-LL-F28249 compounds

Also Published As

Publication number Publication date
KR100367947B1 (ko) 2003-03-26
CZ288894B6 (cs) 2001-09-12
TW319770B (de) 1997-11-11
EP0688775A1 (de) 1995-12-27
CZ153895A3 (en) 1996-01-17
AU681785C (en) 2007-11-01
JP3817756B2 (ja) 2006-09-06
CN1117969A (zh) 1996-03-06
PT688775E (pt) 2002-07-31
IL114246A0 (en) 1995-10-31
KR960000890A (ko) 1996-01-25
AU681785B2 (en) 1997-09-04
US5478951A (en) 1995-12-26
HU9501834D0 (en) 1995-08-28
DE69525686T2 (de) 2002-09-12
SK283198B6 (sk) 2003-03-04
BR9502869A (pt) 1996-11-05
EP0688775B1 (de) 2002-03-06
CA2152249A1 (en) 1995-12-23
ZA955106B (en) 1996-12-20
AU2176695A (en) 1996-01-04
SI0688775T1 (en) 2002-06-30
HU216278B (hu) 1999-05-28
JPH0853456A (ja) 1996-02-27
SK82495A3 (en) 1996-01-10
HUT72831A (en) 1996-05-28
ATE214071T1 (de) 2002-03-15
CN1063445C (zh) 2001-03-21
ES2172554T3 (es) 2002-10-01
DK0688775T3 (da) 2002-06-03
DE69525686D1 (de) 2002-04-11

Similar Documents

Publication Publication Date Title
KR100442717B1 (ko) 세프디니르의 결정성 아민 염
JPS63255286A (ja) １３−スピロ−２−〔テトラヒドロフラン〕−ミルベマイシン誘導体、その製造方法、該化合物を含有する組成物及び寄生虫防除のためのその使用方法
CA2123055A1 (en) Peptidic ketones as interleukin-1 beta-converting enzyme inhibitors
EP1067125B1 (de) VERFAHREN ZUR HERSTELLUNG VON threo-1,2-EPOXY-3-AMINO-4-PHENYLBUTAN-DERIVATEN
WO1996029072A1 (en) Anthelmintic use of nodulisporic acid and analogs thereof
US6486195B1 (en) Thermodynamically stable crystal form of 4″-deoxy-4″-epi-methylamino avermectin B1a/B1b benzoic acid salt and processes for its preparation
EP0688775B1 (de) Verfahren zur Reinigung von 23-E Isomeren von 23-Imino LL-F28249 Derivate
US5677332A (en) Antiparasitic agents
SU648099A3 (ru) Способ получени галогенпроизводных антибиотика изо-лазалоцида а
US6835829B2 (en) Purification process
FR2474503A1 (fr) Composes intermediaires utiles pour l'obtention de la spectinomycine et de ses analogues ainsi que l'utilisation de ces produits
FR2523583A1 (fr) Procede de production de 6'-alkylspectinomycines et de leurs analogues et nouveaux composes intermediaires utilises dans ce procede
IE912199A1 (en) Antiparasitic agents
RU2304583C1 (ru) Способ синтеза ди- и триаминохлоринов
CA2196102A1 (fr) Derives de streptogramine, leur preparation et les compositions pharmaceutiques qui les contiennent
CA2042418A1 (en) Avermectin derivatives with a spacer inserted between the disaccharide and the aglycone useful as antiparasitic agents
HU198056B (en) Process for producing 13-beta-alkyl derivatives of antibiotic s541
FR3121440A1 (fr) Procédé de préparation de la 4’,5’-dihydrocéfradine
EP0217742A2 (de) 5-Ester von Milbemycinen zur Bekämpfung von parasitären Schädlingen
BE887456R (fr) Procede de production de composes intermediaires pour l'obtention de la spectinomycine et de ses analogues et produits de ce procede
FR2460953A1 (fr) Nouveau procede de preparation d'anomeres et de melanges asteriques de nouveaux analogues de spectinomycine
BE639292A (de)
KR20240056726A (ko) 니로가세스타트의 합성
JP3061476B2 (ja) エトポシド燐酸エステルの製造法
CH616424A5 (de)

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees