IL111862A - תולדות אזאביציקלוהפטאן n-מותמרות - Google Patents

תולדות אזאביציקלוהפטאן n-מותמרות

Info

Publication number
IL111862A
IL111862A IL11186294A IL11186294A IL111862A IL 111862 A IL111862 A IL 111862A IL 11186294 A IL11186294 A IL 11186294A IL 11186294 A IL11186294 A IL 11186294A IL 111862 A IL111862 A IL 111862A
Authority
IL
Israel
Prior art keywords
azabicyclo
exo
ethyl
heptan
fluorophenyl
Prior art date
Application number
IL11186294A
Other languages
English (en)
Other versions
IL111862A0 (en
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of IL111862A0 publication Critical patent/IL111862A0/xx
Publication of IL111862A publication Critical patent/IL111862A/he

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL11186294A 1993-12-04 1994-12-02 תולדות אזאביציקלוהפטאן n-מותמרות IL111862A (he)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4341402A DE4341402A1 (de) 1993-12-04 1993-12-04 N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung

Publications (2)

Publication Number Publication Date
IL111862A0 IL111862A0 (en) 1995-03-15
IL111862A true IL111862A (he) 1999-03-12

Family

ID=6504204

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11186294A IL111862A (he) 1993-12-04 1994-12-02 תולדות אזאביציקלוהפטאן n-מותמרות

Country Status (22)

Country Link
US (1) US5616705A (he)
EP (1) EP0740658B1 (he)
JP (1) JP3883567B2 (he)
KR (1) KR100331407B1 (he)
CN (1) CN1054844C (he)
AT (1) ATE244222T1 (he)
AU (1) AU679812B2 (he)
BR (1) BR9408244A (he)
DE (2) DE4341402A1 (he)
ES (1) ES2202348T3 (he)
FI (1) FI962323A0 (he)
HR (1) HRP940960A2 (he)
HU (1) HU220070B (he)
IL (1) IL111862A (he)
NO (1) NO306400B1 (he)
NZ (1) NZ276411A (he)
PL (1) PL314840A1 (he)
RU (1) RU2136678C1 (he)
TW (1) TW324007B (he)
UA (1) UA44721C2 (he)
WO (1) WO1995015312A1 (he)
ZA (1) ZA949593B (he)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4427648A1 (de) * 1994-08-04 1996-02-08 Basf Ag N-Stubstituierte 3-Azabicyclo[3,2,0,]heptan-Derivate, ihre Herstellung und Verwendung
DE4341402A1 (de) * 1993-12-04 1995-06-08 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE4427647A1 (de) * 1994-08-04 1996-02-08 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
NZ509211A (en) 1998-07-17 2002-10-25 Agouron Pharma 1-[2-oxo-3,9-diaza-bicyclo[3.3.1]-non-9-yl]ethane-1,2-dione or 1-[2-oxo-3,10-diaza-bicyclo[4.3.1]dec-20-yl]-ethane-1,2-dione derivatives useful as inhibitors of peptidyl-prolyl isomerase (rotamase) enzyme activity of the FK-506 binding protein
DE19836404A1 (de) * 1998-08-12 2000-02-17 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE19836406A1 (de) * 1998-08-12 2000-02-17 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
US6458821B1 (en) 1998-08-12 2002-10-01 Abbott Laboratories N-substituted azabicycloheptane derivatives, production and use thereof
FR2791345B1 (fr) * 1999-03-26 2001-05-04 Adir Nouveaux derives du benzo[3,4]cyclobuta[1,2-c]pyrrole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CA2495589A1 (en) * 2002-08-14 2004-02-26 Abbott Laboratories Azabicyclic compounds are central nervous system active agents
US7135484B2 (en) 2002-08-14 2006-11-14 Abbott Laboratories Azabicyclic compounds are central nervous system active agents
US7288562B2 (en) 2002-08-23 2007-10-30 Ranbaxy Laboratories Limited Fluoro and sulphonylamino containing 3,6-disubstituted azabicyclo (3.1.0) hexane derivatives as muscarinic receptor antagonists
FR2953514B1 (fr) * 2009-12-09 2011-12-23 Servier Lab Nouveaux derives azabicyclo[3.2.0]hept-3-yl, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN105473554B (zh) * 2013-07-10 2019-08-13 沃泰克斯药物股份有限公司 作为离子通道调节剂的稠合的哌啶酰胺类

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4112353A1 (de) * 1991-04-16 1992-10-22 Basf Ag 1,3,4-trisubstituierte piperidin-derivate, ihre herstellung und verwendung
DE4243287A1 (de) * 1992-06-19 1993-12-23 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE4219973A1 (de) * 1992-06-19 1993-12-23 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE4341402A1 (de) * 1993-12-04 1995-06-08 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung

Also Published As

Publication number Publication date
ES2202348T3 (es) 2004-04-01
US5616705A (en) 1997-04-01
FI962323A (fi) 1996-06-03
HUT75315A (en) 1997-05-28
RU2136678C1 (ru) 1999-09-10
NO962285D0 (no) 1996-06-03
CN1136807A (zh) 1996-11-27
AU679812B2 (en) 1997-07-10
NO306400B1 (no) 1999-11-01
BR9408244A (pt) 1997-05-27
PL314840A1 (en) 1996-09-30
DE4341402A1 (de) 1995-06-08
JP3883567B2 (ja) 2007-02-21
DE59410304D1 (de) 2003-08-07
HRP940960A2 (en) 1997-10-31
NZ276411A (en) 1997-11-24
CN1054844C (zh) 2000-07-26
EP0740658A1 (de) 1996-11-06
TW324007B (en) 1998-01-01
EP0740658B1 (de) 2003-07-02
UA44721C2 (uk) 2002-03-15
IL111862A0 (en) 1995-03-15
WO1995015312A1 (de) 1995-06-08
NO962285L (no) 1996-06-03
ZA949593B (en) 1996-06-03
HU220070B (hu) 2001-10-28
HU9601511D0 (en) 1996-07-29
ATE244222T1 (de) 2003-07-15
KR100331407B1 (ko) 2002-12-05
JPH09505820A (ja) 1997-06-10
AU1067195A (en) 1995-06-19
FI962323A0 (fi) 1996-06-03

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Legal Events

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FF Patent granted
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KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees