IL110968A0 - Nucleosides, nucleotides and oligonucleotides comprising tris-4,4',4"-tert-butylphenylmethyl, as protected group and their preparation - Google Patents

Nucleosides, nucleotides and oligonucleotides comprising tris-4,4',4"-tert-butylphenylmethyl, as protected group and their preparation

Info

Publication number
IL110968A0
IL110968A0 IL11096894A IL11096894A IL110968A0 IL 110968 A0 IL110968 A0 IL 110968A0 IL 11096894 A IL11096894 A IL 11096894A IL 11096894 A IL11096894 A IL 11096894A IL 110968 A0 IL110968 A0 IL 110968A0
Authority
IL
Israel
Prior art keywords
nucleotides
nucleosides
oligonucleotides
butylphenylmethyl
tris
Prior art date
Application number
IL11096894A
Other languages
English (en)
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of IL110968A0 publication Critical patent/IL110968A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL11096894A 1993-09-17 1994-09-14 Nucleosides, nucleotides and oligonucleotides comprising tris-4,4',4"-tert-butylphenylmethyl, as protected group and their preparation IL110968A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH281393 1993-09-17

Publications (1)

Publication Number Publication Date
IL110968A0 true IL110968A0 (en) 1994-11-28

Family

ID=4242181

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11096894A IL110968A0 (en) 1993-09-17 1994-09-14 Nucleosides, nucleotides and oligonucleotides comprising tris-4,4',4"-tert-butylphenylmethyl, as protected group and their preparation

Country Status (13)

Country Link
US (1) US5639867A (xx)
EP (1) EP0644196B1 (xx)
JP (1) JPH07165787A (xx)
KR (1) KR950008530A (xx)
CN (1) CN1111249A (xx)
AT (1) ATE159949T1 (xx)
AU (1) AU671387B2 (xx)
CA (1) CA2132133A1 (xx)
DE (1) DE59404522D1 (xx)
DK (1) DK0644196T3 (xx)
ES (1) ES2110726T3 (xx)
IL (1) IL110968A0 (xx)
ZA (1) ZA947180B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9701219D0 (sv) * 1997-04-04 1997-04-04 Astra Pharma Prod New compounds
EP0979233A4 (en) * 1997-04-21 2001-03-21 Proligo L L C METHOD FOR SYNTHESIS OF OLIGONUCLEOTIDES IN SOLUTION
US6414137B1 (en) * 1998-12-23 2002-07-02 Alliedsignal Inc. Selective solvent extraction for the purification of protected nucleosides
CA2370478A1 (en) 1999-03-24 2000-09-28 Serge L. Beaucage N-acylphosphoramidites and their use in oligonucleotide synthesis
CA2386285A1 (en) * 2001-05-15 2002-11-15 Hironori Komatsu Method for purifying 5' -protected thymidines and novel derivatives thereof
US7355037B2 (en) * 2001-12-03 2008-04-08 The United States Of America As Represented By The Department Of Health And Human Services Thermolabile hydroxyl protecting groups and methods of use
US7002006B2 (en) * 2003-02-12 2006-02-21 Isis Pharmaceuticals, Inc. Protection of nucleosides
WO2006065751A2 (en) * 2004-12-13 2006-06-22 Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Cpg oligonucleotide prodrugs, compositions thereof and associated therapeutic methods
CN102344477B (zh) 2010-07-27 2015-04-08 苏州瑞博生物技术有限公司 一种核苷酸和/或寡核苷酸及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW323284B (xx) * 1992-03-23 1997-12-21 Novartis Ag

Also Published As

Publication number Publication date
EP0644196B1 (de) 1997-11-05
ES2110726T3 (es) 1998-02-16
CN1111249A (zh) 1995-11-08
JPH07165787A (ja) 1995-06-27
EP0644196A1 (de) 1995-03-22
ATE159949T1 (de) 1997-11-15
DE59404522D1 (de) 1997-12-11
KR950008530A (ko) 1995-04-19
AU671387B2 (en) 1996-08-22
CA2132133A1 (en) 1995-03-18
ZA947180B (en) 1995-03-17
US5639867A (en) 1997-06-17
DK0644196T3 (da) 1998-07-27
AU7304394A (en) 1995-03-30

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