IL110783A0 - Benzodiazepine derivatives, their preparation and pharmaceutical compositions containing them - Google Patents
Benzodiazepine derivatives, their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL110783A0 IL110783A0 IL11078394A IL11078394A IL110783A0 IL 110783 A0 IL110783 A0 IL 110783A0 IL 11078394 A IL11078394 A IL 11078394A IL 11078394 A IL11078394 A IL 11078394A IL 110783 A0 IL110783 A0 IL 110783A0
- Authority
- IL
- Israel
- Prior art keywords
- pct
- date
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Child & Adolescent Psychology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Nutrition Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Fats And Perfumes (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Lubricants (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9317693A GB2282595A (en) | 1993-08-25 | 1993-08-25 | Benzodiazepine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL110783A0 true IL110783A0 (en) | 1994-11-11 |
Family
ID=10741026
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11078394A IL110783A0 (en) | 1993-08-25 | 1994-08-25 | Benzodiazepine derivatives, their preparation and pharmaceutical compositions containing them |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5728829A (xx) |
| EP (1) | EP0715624B1 (xx) |
| JP (1) | JPH09504005A (xx) |
| KR (1) | KR960703873A (xx) |
| CN (1) | CN1129442A (xx) |
| AT (1) | ATE164840T1 (xx) |
| AU (1) | AU687433B2 (xx) |
| CA (1) | CA2169089A1 (xx) |
| CZ (1) | CZ53096A3 (xx) |
| DE (1) | DE69409534T2 (xx) |
| DK (1) | DK0715624T3 (xx) |
| ES (1) | ES2117797T3 (xx) |
| FI (1) | FI960836A (xx) |
| GB (1) | GB2282595A (xx) |
| HU (1) | HUT73978A (xx) |
| IL (1) | IL110783A0 (xx) |
| NO (1) | NO960747L (xx) |
| NZ (1) | NZ271131A (xx) |
| PL (1) | PL313165A1 (xx) |
| WO (1) | WO1995006040A1 (xx) |
| ZA (1) | ZA946474B (xx) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT948495E (pt) | 1996-11-19 | 2004-08-31 | Amgen Inc | Agentes anti-inflamatorios de pirrolo fundido substituidos em arilo e heteroarilo |
| ATE248823T1 (de) * | 1996-12-10 | 2003-09-15 | Zeria Pharm Co Ltd | 1,5-benzodiazepinderivate |
| FR2782997A1 (fr) * | 1998-09-08 | 2000-03-10 | Hoechst Marion Roussel Inc | Nouveaux derives de la benzodiazepinone, procede de preparation et intermediaires de ce procede, application a titre de medicaments et compositions pharmaceutiques les renfermant |
| JPWO2002092096A1 (ja) * | 2001-05-11 | 2004-08-26 | 山之内製薬株式会社 | 抗腫瘍剤 |
| GB0221923D0 (en) * | 2002-09-20 | 2002-10-30 | Arrow Therapeutics Ltd | Chemical compounds |
| CN1812982B (zh) * | 2003-06-26 | 2010-10-27 | 默沙东公司 | 苯并二氮杂*cgrp受体拮抗剂 |
| JP5197361B2 (ja) * | 2005-06-06 | 2013-05-15 | ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティー オブ イリノイ | 睡眠障害を処置するための組成物および方法 |
| CN106163527A (zh) | 2013-11-22 | 2016-11-23 | Cl生物科技有限责任公司 | 用于治疗和预防骨质疏松症的胃泌素拮抗剂 |
| GB201414116D0 (en) | 2014-08-08 | 2014-09-24 | Trio Medicines Ltd | Benzodiazepine derivatives |
| GB201513979D0 (en) | 2015-08-07 | 2015-09-23 | Trio Medicines Ltd | Synthesis of benzodiazepine derivatives |
| US10881667B2 (en) | 2018-10-30 | 2021-01-05 | City University Of Hong Kong | Method and composition for treating epilepsy |
| CN109553591B (zh) * | 2019-01-15 | 2020-12-15 | 山东安信制药有限公司 | 一种富马酸喹硫平中间体的制备方法 |
| US11285161B2 (en) | 2019-04-26 | 2022-03-29 | City University Of Hong Kong | Method and composition for treating mental disorder and pain associated with nerve damage |
| FR3097222B1 (fr) * | 2019-06-11 | 2021-05-28 | Michelin & Cie | Nouveaux composes 1,3-dipolaires comprenant un heterocycle aromatique et un cycle imidazole |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4820834A (en) * | 1984-06-26 | 1989-04-11 | Merck & Co., Inc. | Benzodiazepine analogs |
| IL96613A0 (en) * | 1989-12-18 | 1991-09-16 | Merck & Co Inc | Pharmaceutical compositions containing benzodiazepine analogs |
| JPH07119217B1 (xx) * | 1990-12-25 | 1995-12-20 | ||
| GB9116113D0 (en) * | 1991-07-25 | 1991-09-11 | Merck Sharp & Dohme | Therapeutic agents |
| FR2682381B1 (fr) * | 1991-10-10 | 1995-04-07 | Rhone Poulenc Rorer Sa | Derives de benzodiazepine, leur preparation et les medicaments les contenant. |
| WO1993007131A1 (en) * | 1991-10-10 | 1993-04-15 | Merck Sharp & Dohme Limited | Benzodiazepine derivatives and their use as antagonists of cholecystokinin and/or gastrin receptors |
| WO1993008175A1 (en) * | 1991-10-24 | 1993-04-29 | Glaxo Group Limited | Benzodiazepine derivatives as antagonists of gastrin and/or cholecystokinin |
| IL104853A (en) * | 1992-02-27 | 1997-11-20 | Yamanouchi Pharma Co Ltd | Benzodiazepine derivatives, their preparation and pharmaceutical compositions containing them |
| GB2264492B (en) * | 1992-02-27 | 1996-09-25 | Yamanouchi Pharma Co Ltd | Benzodiazepine derivatives |
| WO1994000438A1 (en) * | 1992-06-24 | 1994-01-06 | Yamanouchi Pharmaceutical Co., Ltd. | Novel benzodiazepine derivative |
-
1993
- 1993-08-25 GB GB9317693A patent/GB2282595A/en not_active Withdrawn
-
1994
- 1994-08-25 EP EP94924368A patent/EP0715624B1/en not_active Expired - Lifetime
- 1994-08-25 ES ES94924368T patent/ES2117797T3/es not_active Expired - Lifetime
- 1994-08-25 PL PL94313165A patent/PL313165A1/xx unknown
- 1994-08-25 CA CA002169089A patent/CA2169089A1/en not_active Abandoned
- 1994-08-25 IL IL11078394A patent/IL110783A0/xx unknown
- 1994-08-25 NZ NZ271131A patent/NZ271131A/en not_active IP Right Cessation
- 1994-08-25 DK DK94924368T patent/DK0715624T3/da active
- 1994-08-25 JP JP7507439A patent/JPH09504005A/ja active Pending
- 1994-08-25 US US08/591,567 patent/US5728829A/en not_active Expired - Lifetime
- 1994-08-25 CN CN94193134A patent/CN1129442A/zh active Pending
- 1994-08-25 ZA ZA946474A patent/ZA946474B/xx unknown
- 1994-08-25 HU HU9600205A patent/HUT73978A/hu unknown
- 1994-08-25 DE DE69409534T patent/DE69409534T2/de not_active Expired - Lifetime
- 1994-08-25 KR KR1019960700905A patent/KR960703873A/ko not_active Application Discontinuation
- 1994-08-25 CZ CZ96530A patent/CZ53096A3/cs unknown
- 1994-08-25 WO PCT/GB1994/001859 patent/WO1995006040A1/en not_active Application Discontinuation
- 1994-08-25 AT AT94924368T patent/ATE164840T1/de active
- 1994-08-25 AU AU74661/94A patent/AU687433B2/en not_active Ceased
-
1996
- 1996-02-23 FI FI960836A patent/FI960836A/fi unknown
- 1996-02-23 NO NO960747A patent/NO960747L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU7466194A (en) | 1995-03-21 |
| FI960836A (fi) | 1996-04-22 |
| DE69409534T2 (de) | 1998-08-06 |
| CN1129442A (zh) | 1996-08-21 |
| DK0715624T3 (da) | 1999-01-11 |
| DE69409534D1 (de) | 1998-05-14 |
| WO1995006040A1 (en) | 1995-03-02 |
| ZA946474B (en) | 1996-03-25 |
| NO960747D0 (no) | 1996-02-23 |
| NZ271131A (en) | 1997-11-24 |
| HUT73978A (en) | 1996-10-28 |
| GB9317693D0 (en) | 1993-10-13 |
| ATE164840T1 (de) | 1998-04-15 |
| JPH09504005A (ja) | 1997-04-22 |
| CA2169089A1 (en) | 1995-03-02 |
| CZ53096A3 (en) | 1996-09-11 |
| EP0715624A1 (en) | 1996-06-12 |
| FI960836A0 (fi) | 1996-02-23 |
| KR960703873A (ko) | 1996-08-31 |
| HU9600205D0 (en) | 1996-04-29 |
| AU687433B2 (en) | 1998-02-26 |
| EP0715624B1 (en) | 1998-04-08 |
| GB2282595A (en) | 1995-04-12 |
| ES2117797T3 (es) | 1998-08-16 |
| US5728829A (en) | 1998-03-17 |
| PL313165A1 (en) | 1996-06-10 |
| NO960747L (no) | 1996-04-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HC | Change of name of proprietor(s) |