IL110621A - Taste-masked microencapsulated non-steroidal anti-inflammatory drugs (nsaid) and their preparation - Google Patents

Taste-masked microencapsulated non-steroidal anti-inflammatory drugs (nsaid) and their preparation

Info

Publication number
IL110621A
IL110621A IL11062194A IL11062194A IL110621A IL 110621 A IL110621 A IL 110621A IL 11062194 A IL11062194 A IL 11062194A IL 11062194 A IL11062194 A IL 11062194A IL 110621 A IL110621 A IL 110621A
Authority
IL
Israel
Prior art keywords
masked
taste
microencapsulation
nsaid
water
Prior art date
Application number
IL11062194A
Other languages
English (en)
Other versions
IL110621A0 (en
Original Assignee
Eurand America Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eurand America Inc filed Critical Eurand America Inc
Publication of IL110621A0 publication Critical patent/IL110621A0/xx
Publication of IL110621A publication Critical patent/IL110621A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A61K9/5057—Gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL11062194A 1993-08-13 1994-08-10 Taste-masked microencapsulated non-steroidal anti-inflammatory drugs (nsaid) and their preparation IL110621A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10602493A 1993-08-13 1993-08-13

Publications (2)

Publication Number Publication Date
IL110621A0 IL110621A0 (en) 1994-11-11
IL110621A true IL110621A (en) 1999-10-28

Family

ID=22309067

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11062194A IL110621A (en) 1993-08-13 1994-08-10 Taste-masked microencapsulated non-steroidal anti-inflammatory drugs (nsaid) and their preparation

Country Status (14)

Country Link
US (2) US5653993A (xx)
EP (1) EP0818992B1 (xx)
AT (1) ATE216578T1 (xx)
AU (1) AU7559594A (xx)
BR (1) BR9407246A (xx)
CA (1) CA2169376C (xx)
DE (1) DE69430491T2 (xx)
DK (1) DK0818992T3 (xx)
ES (1) ES2176254T3 (xx)
IL (1) IL110621A (xx)
MY (1) MY111453A (xx)
PT (1) PT818992E (xx)
WO (1) WO1995005166A1 (xx)
ZA (1) ZA945944B (xx)

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AU719137B2 (en) * 1996-05-07 2000-05-04 Mayne Pharma International Pty Ltd Taste masked liquid suspensions
AUPN969796A0 (en) * 1996-05-07 1996-05-30 F.H. Faulding & Co. Limited Taste masked liquid suspensions
FR2753093B1 (fr) * 1996-09-06 1998-10-16 Oreal Composition de teinture d'oxydation pour fibres keratiniques comprenant un polymere amphiphile anionique
JP2001505188A (ja) 1996-09-26 2001-04-17 オゥクラホゥマ、メディカル、リサーチ、ファウンデイシャン Ｎ―Ｌ―α―アスパルチル―Ｌ―フェニルアラニン１―メチルエステル及びその誘導体の疾患後退への使用
GB9625589D0 (en) 1996-12-10 1997-01-29 Boots Co Plc Therapeutic agents
US5904937A (en) * 1997-10-03 1999-05-18 Fmc Corporation Taste masked pharmaceutical compositions
FR2785538B1 (fr) * 1998-11-06 2004-04-09 Prographarm Laboratoires Comprime a delitement rapide perfectionne
FR2785539B1 (fr) * 1998-11-06 2004-04-09 Prographarm Laboratoires Particules enrobees d'ibuprofene cristallin granule
ATE288257T1 (de) 1999-04-06 2005-02-15 Ethypharm Sa Trinkbare pharmazeutische suspension von ibuprofen
CN1288730A (zh) * 1999-09-07 2001-03-28 麦克内尔-Ppc股份有限公司 轻泻组合物
US7223421B2 (en) * 2000-06-30 2007-05-29 Mcneil-Ppc, Inc. Teste masked pharmaceutical particles
US20020119196A1 (en) * 2000-12-21 2002-08-29 Narendra Parikh Texture masked particles containing an active ingredient
FR2826274B1 (fr) * 2001-06-21 2003-09-26 Aventis Pharma Sa Formulation pharmaceutique au gout masque et son procede de preparation
DK1411899T3 (da) * 2001-08-01 2009-06-02 Novartis Ag Smagsmaskerende sammensætning
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
MXPA04008720A (es) * 2002-03-12 2004-12-06 Squibb Bristol Myers Co Suspension oral de sabor agradable y metodo.
ES2327034T3 (es) * 2002-03-26 2009-10-23 Euro-Celtique S.A. Composiciones recubiertas con gel de liberacion sostenida.
FR2850275B1 (fr) 2003-01-24 2005-04-08 Scherer Technologies Inc R P Capsules molles a macher contenant une substance active a gout masque
US7632521B2 (en) * 2003-07-15 2009-12-15 Eurand, Inc. Controlled release potassium chloride tablets
ITMI20032523A1 (it) * 2003-12-19 2005-06-20 Acraf Forma di dosaggio per uso orale comprendente un farmaco
KR100694235B1 (ko) * 2005-04-21 2007-03-14 영남대학교 산학협력단 새로운 이부프로펜 함유 젤라틴 초미세 미립구
JP5389656B2 (ja) 2006-10-20 2014-01-15 マクニール−ピーピーシー・インコーポレーテツド アセトアミノフェン／イブプロフェンの組み合わせおよびこれらの使用方法
US20080138397A1 (en) * 2006-10-24 2008-06-12 Aradigm Corporation Processes for taste-masking of inhaled formulations
US20100062073A1 (en) * 2006-11-29 2010-03-11 Ronald Arthur Beyerinck Pharmaceutical compositions comprising nanoparticles comprising enteric polymers casein
US20090060983A1 (en) * 2007-08-30 2009-03-05 Bunick Frank J Method And Composition For Making An Orally Disintegrating Dosage Form
CA2704209C (en) * 2007-10-31 2017-02-28 Mcneil-Ppc, Inc. Orally disintegrative dosage form
US8858210B2 (en) 2009-09-24 2014-10-14 Mcneil-Ppc, Inc. Manufacture of variable density dosage forms utilizing radiofrequency energy
US8313768B2 (en) 2009-09-24 2012-11-20 Mcneil-Ppc, Inc. Manufacture of tablet having immediate release region and sustained release region
US9610224B2 (en) 2009-09-24 2017-04-04 Johnson & Johnson Consumer Inc. Manufacture of tablet in a die utilizing powder blend containing water-containing material
US20110070286A1 (en) * 2009-09-24 2011-03-24 Andreas Hugerth Process for the manufacture of nicotine-comprising chewing gum and nicotine-comprising chewing gum manufactured according to said process
ES2363964B1 (es) 2009-11-20 2012-08-22 Gp Pharm, S.A. Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados.
CA2821504C (en) * 2010-09-20 2019-03-26 Spi Pharma, Inc. Microencapsulation process and product
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
US9511028B2 (en) 2012-05-01 2016-12-06 Johnson & Johnson Consumer Inc. Orally disintegrating tablet
US9445971B2 (en) 2012-05-01 2016-09-20 Johnson & Johnson Consumer Inc. Method of manufacturing solid dosage form
US9233491B2 (en) 2012-05-01 2016-01-12 Johnson & Johnson Consumer Inc. Machine for production of solid dosage forms
RU2015114433A (ru) 2012-09-18 2016-11-10 МакНЕЙЛ-ППС, ИНК. Пероральные дозированные формы с замедленным высвобождением, содержащие частицы легкоплавкого производного пропионовой кислоты
CA2884119A1 (en) 2012-09-18 2014-03-27 Mcneil-Ppc, Inc. Low melting propionic acid derivative particles for use in oral dosage forms
DK2973369T3 (en) 2013-03-12 2018-03-05 Panacea Biomatx Inc METHOD AND SYSTEM FOR MANUFACTURING INDIVIDUAL FORMULATIONS FOR INDIVIDUALS
KR20160107254A (ko) 2014-01-10 2016-09-13 존슨 앤드 존슨 컨수머 인코포레이티드 고주파 및 손실 코팅된 입자를 사용하여 정제를 제조하는 방법
KR20190005199A (ko) 2016-05-05 2019-01-15 어퀘스티브 테라퓨틱스, 아이엔씨. 강화된 전달 에프네프린 조성물
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
US10493026B2 (en) 2017-03-20 2019-12-03 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles

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Publication number Priority date Publication date Assignee Title
IT1148784B (it) * 1980-04-09 1986-12-03 Eurand Spa Procedimento per la preparazione di microcapsule in un veicolo liquido
JPS5858146A (ja) * 1981-10-05 1983-04-06 Tanabe Seiyaku Co Ltd 速放性マイクロカプセル
JPS59193816A (ja) * 1983-04-19 1984-11-02 Morishita Jintan Kk 腸溶性軟カプセルの製造法
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
IT1214629B (it) * 1985-08-29 1990-01-18 Formenti Farmaceutici Spa Procedimento di microincapsulazione di un medicamento,medicamento cosi'preparato,e composizioni farmaceutiche che lo comprendono
IN166447B (xx) * 1985-11-27 1990-05-12 Ethicon Inc
US4835186A (en) * 1987-06-15 1989-05-30 American Home Products Corporation Spray dried ibuprofen
US4835187A (en) * 1987-06-15 1989-05-30 American Home Products Corporation Spray dried ibuprofen
US4835188A (en) * 1987-12-08 1989-05-30 American Home Products Corporation Spray dried ibuprofen
NZ234587A (en) * 1989-08-04 1991-11-26 Mcneil Ppc Inc A chewable pharmaceutical tablet of compressed coated granules
IE902829A1 (en) * 1989-08-14 1991-02-27 Eurand America Microencapsulated taste-masked water-insoluble nsaid drug¹materials

Also Published As

Publication number Publication date
US5653993A (en) 1997-08-05
PT818992E (pt) 2002-08-30
EP0818992B1 (en) 2002-04-24
US5814332A (en) 1998-09-29
ES2176254T3 (es) 2002-12-01
DK0818992T3 (da) 2002-08-19
IL110621A0 (en) 1994-11-11
DE69430491D1 (de) 2002-05-29
WO1995005166A1 (en) 1995-02-23
AU7559594A (en) 1995-03-14
CA2169376A1 (en) 1995-02-23
BR9407246A (pt) 1996-09-24
EP0818992A1 (en) 1998-01-21
DE69430491T2 (de) 2002-08-08
ZA945944B (en) 1996-02-08
ATE216578T1 (de) 2002-05-15
MY111453A (en) 2000-05-31
CA2169376C (en) 2003-10-21

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