IL110227A0 - Difluoro statone analogs - Google Patents
Difluoro statone analogsInfo
- Publication number
- IL110227A0 IL110227A0 IL11022794A IL11022794A IL110227A0 IL 110227 A0 IL110227 A0 IL 110227A0 IL 11022794 A IL11022794 A IL 11022794A IL 11022794 A IL11022794 A IL 11022794A IL 110227 A0 IL110227 A0 IL 110227A0
- Authority
- IL
- Israel
- Prior art keywords
- pct
- analogs
- sec
- difluoro statone
- date
- Prior art date
Links
- PQIOSYKVBBWRRI-UHFFFAOYSA-N methylphosphonyl difluoride Chemical group CP(F)(F)=O PQIOSYKVBBWRRI-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Saccharide Compounds (AREA)
- Phenolic Resins Or Amino Resins (AREA)
- Air Bags (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP93401785 | 1993-07-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL110227A0 true IL110227A0 (en) | 1994-10-21 |
Family
ID=8214732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11022794A IL110227A0 (en) | 1993-07-08 | 1994-07-06 | Difluoro statone analogs |
Country Status (18)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995007257A1 (en) * | 1993-09-09 | 1995-03-16 | Merrell Pharmaceuticals Inc. | Difluoro statone antiviral analogs |
| TW200910648A (en) | 2007-08-31 | 2009-03-01 | Isotech Products Inc | Forming process of resin lens of an LED component |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH672792A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1985-02-19 | 1989-12-29 | Sandoz Ag | |
| US5066643A (en) * | 1985-02-19 | 1991-11-19 | Sandoz Ltd. | Fluorine and chlorine statine or statone containing peptides and method of use |
| WO1986006379A1 (en) * | 1985-04-19 | 1986-11-06 | The Upjohn Company | Dihalo-statine substituted renin inhibitors |
| GB8619182D0 (en) * | 1986-08-06 | 1986-09-17 | Sandoz Ltd | Peptides & derivatives |
| NZ223148A (en) * | 1987-01-16 | 1989-10-27 | Merrell Dow Pharma | Peptide derivatives having peptidase inhibition activity |
| FR2614533A1 (fr) * | 1987-04-23 | 1988-11-04 | Sandoz Sa | Nouveaux derives peptidiques, leur preparation et leur utilisation comme medicaments |
| GB2212158A (en) * | 1987-12-15 | 1989-07-19 | Sandoz Ltd | Trialkylsilymethyl-substituted peptides; renin inhibitors |
| IL90872A0 (en) | 1988-07-08 | 1990-02-09 | Smithkline Beckman Corp | Retroviral protease binding peptides |
| HUT58764A (en) * | 1988-07-08 | 1992-03-30 | Smithkline Beckman Corp | Process for producing peptides, pharmaceutical compositions containing them and amino-acid intermediates |
| CA2010531A1 (en) * | 1989-03-06 | 1990-09-06 | Werner Neidhart | Amino acid derivatives |
| US5151438A (en) * | 1989-05-23 | 1992-09-29 | Abbott Laboratories | Retroviral protease inhibiting compounds |
| EP0565631B1 (en) * | 1991-01-02 | 1996-09-18 | Merrell Pharmaceuticals Inc. | Anti-viral compounds |
| WO1993019059A1 (en) * | 1992-03-25 | 1993-09-30 | Pfizer Limited | Antiviral peptides |
| GB9210744D0 (en) * | 1992-05-20 | 1992-07-08 | Pfizer Ltd | Antiviral peptides |
| EP1148050A1 (en) * | 1992-05-21 | 2001-10-24 | Monsanto Company | Retroviral protease inhibitors |
| CN1152910A (zh) * | 1994-07-15 | 1997-06-25 | 默里尔药物公司 | 二氟斯塔酮抗病毒剂 |
| EP2954134B1 (en) | 2013-02-08 | 2017-09-13 | Tait Towers Manufacturing, LLC | Visually flying platform with visually transparent flexible support members |
-
1994
- 1994-06-07 AT AT94920095T patent/ATE196465T1/de not_active IP Right Cessation
- 1994-06-07 CA CA002166693A patent/CA2166693C/en not_active Expired - Fee Related
- 1994-06-07 EP EP94920095A patent/EP0707564B1/en not_active Expired - Lifetime
- 1994-06-07 WO PCT/US1994/006376 patent/WO1995001958A1/en active IP Right Grant
- 1994-06-07 ES ES94920095T patent/ES2152982T3/es not_active Expired - Lifetime
- 1994-06-07 HU HU9503706A patent/HUT73411A/hu unknown
- 1994-06-07 DE DE69425971T patent/DE69425971T2/de not_active Expired - Lifetime
- 1994-06-07 AU AU71008/94A patent/AU680009B2/en not_active Ceased
- 1994-06-07 KR KR1019960700062A patent/KR100316864B1/ko not_active Expired - Fee Related
- 1994-06-07 JP JP7504027A patent/JPH08512319A/ja active Pending
- 1994-06-07 NZ NZ268202A patent/NZ268202A/en unknown
- 1994-06-07 CN CN94192700A patent/CN1126988A/zh active Pending
- 1994-06-07 US US08/578,698 patent/US5717093A/en not_active Expired - Lifetime
- 1994-07-04 ZA ZA944818A patent/ZA944818B/xx unknown
- 1994-07-05 TW TW083106128A patent/TW288005B/zh active
- 1994-07-06 IL IL11022794A patent/IL110227A0/xx unknown
-
1996
- 1996-01-05 NO NO960048A patent/NO306343B1/no not_active IP Right Cessation
- 1996-01-05 FI FI960051A patent/FI120389B/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU680009B2 (en) | 1997-07-17 |
| DE69425971T2 (de) | 2001-05-23 |
| CA2166693A1 (en) | 1995-01-09 |
| CN1126988A (zh) | 1996-07-17 |
| ES2152982T3 (es) | 2001-02-16 |
| CA2166693C (en) | 1999-08-24 |
| HU9503706D0 (en) | 1996-02-28 |
| US5717093A (en) | 1998-02-10 |
| FI120389B (fi) | 2009-10-15 |
| ZA944818B (en) | 1995-02-22 |
| KR100316864B1 (ko) | 2002-11-13 |
| ATE196465T1 (de) | 2000-10-15 |
| EP0707564A1 (en) | 1996-04-24 |
| FI960051A0 (fi) | 1996-01-05 |
| JPH08512319A (ja) | 1996-12-24 |
| DE69425971D1 (de) | 2000-10-26 |
| NO960048L (no) | 1996-03-05 |
| HUT73411A (en) | 1996-07-29 |
| TW288005B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1996-10-11 |
| FI960051L (fi) | 1996-03-07 |
| WO1995001958A1 (en) | 1995-01-19 |
| NO306343B1 (no) | 1999-10-25 |
| EP0707564B1 (en) | 2000-09-20 |
| NO960048D0 (no) | 1996-01-05 |
| AU7100894A (en) | 1995-02-06 |
| KR960703844A (ko) | 1996-08-31 |
| NZ268202A (en) | 1997-09-22 |
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