IL110204A0 - Novel indolene derivatives, processes for their preparation and their use for the treatment of cns disorders - Google Patents
Novel indolene derivatives, processes for their preparation and their use for the treatment of cns disordersInfo
- Publication number
- IL110204A0 IL110204A0 IL11020494A IL11020494A IL110204A0 IL 110204 A0 IL110204 A0 IL 110204A0 IL 11020494 A IL11020494 A IL 11020494A IL 11020494 A IL11020494 A IL 11020494A IL 110204 A0 IL110204 A0 IL 110204A0
- Authority
- IL
- Israel
- Prior art keywords
- novel
- processes
- preparation
- treatment
- cns disorders
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Eyeglasses (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939313913A GB9313913D0 (en) | 1993-07-06 | 1993-07-06 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL110204A0 true IL110204A0 (en) | 1995-01-24 |
Family
ID=10738344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11020494A IL110204A0 (en) | 1993-07-06 | 1994-07-04 | Novel indolene derivatives, processes for their preparation and their use for the treatment of cns disorders |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5834494A (fr) |
| EP (1) | EP0707581B1 (fr) |
| JP (1) | JPH08512299A (fr) |
| CN (1) | CN1129937A (fr) |
| AP (1) | AP463A (fr) |
| AT (1) | ATE149163T1 (fr) |
| AU (1) | AU7228394A (fr) |
| CA (1) | CA2166624A1 (fr) |
| DE (1) | DE69401823T2 (fr) |
| GB (1) | GB9313913D0 (fr) |
| IL (1) | IL110204A0 (fr) |
| MA (1) | MA23254A1 (fr) |
| TW (1) | TW297023B (fr) |
| WO (1) | WO1995001976A1 (fr) |
| ZA (1) | ZA944807B (fr) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5618824A (en) * | 1994-03-09 | 1997-04-08 | Merrell Pharmaceuticals Inc. | Treatment of obsessive-compulsive disorders with 5-HT2 antagonists |
| GB9414139D0 (en) * | 1994-07-13 | 1994-08-31 | Smithkline Beecham Plc | Novel compounds |
| GB9420521D0 (en) * | 1994-10-12 | 1994-11-30 | Smithkline Beecham Plc | Novel compounds |
| JPH10513443A (ja) * | 1995-02-02 | 1998-12-22 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | ５ＨＴ▲下２ｃ▼レセプターアンタゴニスト活性を有する複素環化合物 |
| ATE197300T1 (de) * | 1995-02-02 | 2000-11-15 | Smithkline Beecham Plc | Indolderivate als 5-ht rezeptorantagoniste |
| GB9517559D0 (en) * | 1995-08-26 | 1995-10-25 | Smithkline Beecham Plc | Novel compounds |
| CA2253941A1 (fr) * | 1996-05-16 | 1997-11-20 | Sumanas Rakhit | Derives de la thiophenetryptamine et de la furanetryptamine |
| GB9612883D0 (en) * | 1996-06-20 | 1996-08-21 | Smithkline Beecham Plc | Novel compounds |
| GB9612885D0 (en) * | 1996-06-20 | 1996-08-21 | Smithkline Beecham Plc | Novel compounds |
| US6362009B1 (en) | 1997-11-21 | 2002-03-26 | Merck & Co., Inc. | Solid phase synthesis of heterocycles |
| FR2778662B1 (fr) * | 1998-05-12 | 2000-06-16 | Adir | Nouveaux composes cycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| CA2347095A1 (fr) * | 1998-10-16 | 2000-04-27 | Takeda Chemical Industries, Ltd. | Composes azotes hererocycliques condenses; procede de fabrication et agents les renfermant |
| US6453357B1 (en) | 1999-01-07 | 2002-09-17 | Cisco Technology, Inc. | Method and system for processing fragments and their out-of-order delivery during address translation |
| CA2374898C (fr) * | 1999-05-21 | 2009-12-08 | Biovitrum Ab | Composes du type pyrazinyle de piperazine et methode de preparation et utilisation connexes |
| US6465467B1 (en) | 1999-05-21 | 2002-10-15 | Biovitrum Ab | Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases |
| UA77650C2 (en) | 1999-12-06 | 2007-01-15 | Lundbeck & Co As H | Use of serotonin reuptake inhibitor in combination with deramcyclane |
| FR2810979B1 (fr) * | 2000-06-29 | 2002-08-23 | Adir | Nouveaux derives de diphenyluree, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| GB0019950D0 (en) * | 2000-08-12 | 2000-09-27 | Smithkline Beecham Plc | Compounds |
| SE0004245D0 (sv) | 2000-11-20 | 2000-11-20 | Pharmacia Ab | Novel compounds and their use |
| ATE241155T1 (de) * | 2001-07-09 | 2003-06-15 | Cit Alcatel | Verbinder für optische fasern |
| US6861440B2 (en) | 2001-10-26 | 2005-03-01 | Hoffmann-La Roche Inc. | DPP IV inhibitors |
| FR2837823B1 (fr) * | 2002-03-27 | 2005-04-08 | Servier Lab | Nouveaux derives d'indoline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| CN100484933C (zh) | 2002-06-19 | 2009-05-06 | 比奥维特罗姆股份公开公司 | 新的吡嗪化合物及其在制备用于治疗与5-羟色胺相关的疾病的药物中的用途 |
| RS52397B (en) | 2003-06-20 | 2013-02-28 | F.Hoffmann-La Roche Ag | PYRIDO / 2,1-A / ISOCHINOLINE DERIVATIVES AS DPP-IV INHIBITORS |
| KR100744893B1 (ko) | 2003-06-20 | 2007-08-01 | 에프. 호프만-라 로슈 아게 | Ｄｐｐ-ｉｖ 저해제로서 헥사하이드로피리도아이소퀴놀린 |
| ATE521588T1 (de) * | 2005-09-13 | 2011-09-15 | Bayer Cropscience Ag | Phenyloxy-substituierte phenylamidin-derivate als pestizide |
| US9052304B2 (en) | 2009-03-13 | 2015-06-09 | Terrasep, Llc | Methods and apparatus for centrifugal liquid chromatography |
| CN106278987A (zh) * | 2016-08-16 | 2017-01-04 | 都创(上海)医药科技有限公司 | 吲哚啉类化合物的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4428881A (en) * | 1977-12-23 | 1984-01-31 | Gulf Oil Corporation | Control of unwanted vegetation with N-carbamylindolines |
| CA2091246A1 (fr) * | 1990-09-13 | 1992-03-14 | Ian Thomson Forbes | Indoluree utilisee comme antagoniste du recepteur de la 5 ht |
| JPH08500580A (ja) * | 1992-08-20 | 1996-01-23 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | ５ｈｔ▲下２ｃ▼および５ｈｔ▲下２ｂ▼拮抗薬用縮合インドール誘導体 |
-
1993
- 1993-07-06 GB GB939313913A patent/GB9313913D0/en active Pending
-
1994
- 1994-06-30 DE DE69401823T patent/DE69401823T2/de not_active Expired - Fee Related
- 1994-06-30 AU AU72283/94A patent/AU7228394A/en not_active Abandoned
- 1994-06-30 EP EP94921638A patent/EP0707581B1/fr not_active Expired - Lifetime
- 1994-06-30 JP JP7503812A patent/JPH08512299A/ja active Pending
- 1994-06-30 AT AT94921638T patent/ATE149163T1/de not_active IP Right Cessation
- 1994-06-30 WO PCT/EP1994/002148 patent/WO1995001976A1/fr active IP Right Grant
- 1994-06-30 CN CN94193185A patent/CN1129937A/zh active Pending
- 1994-06-30 CA CA002166624A patent/CA2166624A1/fr not_active Abandoned
- 1994-07-04 ZA ZA944807A patent/ZA944807B/xx unknown
- 1994-07-04 IL IL11020494A patent/IL110204A0/xx unknown
- 1994-07-04 AP APAP/P/1994/000653A patent/AP463A/en active
- 1994-07-04 MA MA23564A patent/MA23254A1/fr unknown
- 1994-07-05 TW TW083106150A patent/TW297023B/zh active
-
1996
- 1996-09-23 US US08/717,957 patent/US5834494A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2166624A1 (fr) | 1995-01-19 |
| JPH08512299A (ja) | 1996-12-24 |
| DE69401823D1 (de) | 1997-04-03 |
| TW297023B (fr) | 1997-02-01 |
| ATE149163T1 (de) | 1997-03-15 |
| DE69401823T2 (de) | 1997-08-28 |
| MA23254A1 (fr) | 1995-04-01 |
| WO1995001976A1 (fr) | 1995-01-19 |
| US5834494A (en) | 1998-11-10 |
| AP9400653A0 (en) | 1994-07-31 |
| AP463A (en) | 1996-02-19 |
| AU7228394A (en) | 1995-02-06 |
| CN1129937A (zh) | 1996-08-28 |
| GB9313913D0 (en) | 1993-08-18 |
| EP0707581A1 (fr) | 1996-04-24 |
| EP0707581B1 (fr) | 1997-02-26 |
| ZA944807B (en) | 1996-01-04 |
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