IL108726A - Electrobiochemical method and system for the determination of an analyte which is a member of a recognition pair in a liquid medium and electrodes therefor - Google Patents

Electrobiochemical method and system for the determination of an analyte which is a member of a recognition pair in a liquid medium and electrodes therefor

Info

Publication number
IL108726A
IL108726A IL10872694A IL10872694A IL108726A IL 108726 A IL108726 A IL 108726A IL 10872694 A IL10872694 A IL 10872694A IL 10872694 A IL10872694 A IL 10872694A IL 108726 A IL108726 A IL 108726A
Authority
IL
Israel
Prior art keywords
electrode
analyte
immobilized
state
concentration
Prior art date
Application number
IL10872694A
Other languages
English (en)
Other versions
IL108726A0 (en
Inventor
Itamar Willner
Arie Dagan
Shai Rubin
Ron Blonder
Azalia Riklin
Yael Cohen
Original Assignee
Yissum Res Dev Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Res Dev Co filed Critical Yissum Res Dev Co
Priority to IL10872694A priority Critical patent/IL108726A/en
Publication of IL108726A0 publication Critical patent/IL108726A0/xx
Priority to DE69526747T priority patent/DE69526747T2/de
Priority to DK95102343T priority patent/DK0668502T3/da
Priority to AT95102343T priority patent/ATE217966T1/de
Priority to ES95102343T priority patent/ES2177586T3/es
Priority to EP95102343A priority patent/EP0668502B1/de
Priority to US08/390,978 priority patent/US5942388A/en
Priority to JP05815895A priority patent/JP3583496B2/ja
Publication of IL108726A publication Critical patent/IL108726A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/004—Enzyme electrodes mediator-assisted
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/002—Electrode membranes
    • C12Q1/003—Functionalisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/552—Glass or silica
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/806—Electrical property or magnetic property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/825—Pretreatment for removal of interfering factors from sample

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Inorganic Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Hybrid Cells (AREA)
IL10872694A 1994-02-22 1994-02-22 Electrobiochemical method and system for the determination of an analyte which is a member of a recognition pair in a liquid medium and electrodes therefor IL108726A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IL10872694A IL108726A (en) 1994-02-22 1994-02-22 Electrobiochemical method and system for the determination of an analyte which is a member of a recognition pair in a liquid medium and electrodes therefor
DE69526747T DE69526747T2 (de) 1994-02-22 1995-02-20 Elektrobiochemisches Verfahren, System und Elektroden zur Bestimmung eines Mitgliedes eines Bindungspaares
DK95102343T DK0668502T3 (da) 1994-02-22 1995-02-20 Elektrobiokemisk fremgangsmåde, system og elektroder til bestemmelse af en del af et bindingspar
AT95102343T ATE217966T1 (de) 1994-02-22 1995-02-20 Elektrobiochemisches verfahren, system und elektroden zur bestimmung eines mitgliedes eines bindungspaares
ES95102343T ES2177586T3 (es) 1994-02-22 1995-02-20 Un procedimiento electrobioquimico, sistema y electrodos para determinar un miembro de un par de reconocimiento.
EP95102343A EP0668502B1 (de) 1994-02-22 1995-02-20 Elektrobiochemisches Verfahren, System und Elektroden zur Bestimmung eines Mitgliedes eines Bindungspaares
US08/390,978 US5942388A (en) 1994-02-22 1995-02-21 Electrobiochemical method and system for the determination of an analyte which is a member of a recognition pair in a liquid medium, and electrodes thereof
JP05815895A JP3583496B2 (ja) 1994-02-22 1995-02-22 液体媒質中の認識対の構成員である被検体の決定のための電気生化学的方法および系ならびにその電極

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL10872694A IL108726A (en) 1994-02-22 1994-02-22 Electrobiochemical method and system for the determination of an analyte which is a member of a recognition pair in a liquid medium and electrodes therefor

Publications (2)

Publication Number Publication Date
IL108726A0 IL108726A0 (en) 1994-05-30
IL108726A true IL108726A (en) 1999-12-31

Family

ID=11065843

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10872694A IL108726A (en) 1994-02-22 1994-02-22 Electrobiochemical method and system for the determination of an analyte which is a member of a recognition pair in a liquid medium and electrodes therefor

Country Status (8)

Country Link
US (1) US5942388A (de)
EP (1) EP0668502B1 (de)
JP (1) JP3583496B2 (de)
AT (1) ATE217966T1 (de)
DE (1) DE69526747T2 (de)
DK (1) DK0668502T3 (de)
ES (1) ES2177586T3 (de)
IL (1) IL108726A (de)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6770179B1 (en) * 1993-05-10 2004-08-03 Universite De Montreal Biosensors comprising a covalently attached monomolecular biological conjugate layer and a transducing device
US6071699A (en) 1996-06-07 2000-06-06 California Institute Of Technology Nucleic acid mediated electron transfer
US5620850A (en) * 1994-09-26 1997-04-15 President And Fellows Of Harvard College Molecular recognition at surfaces derivatized with self-assembled monolayers
IL114692A (en) 1995-07-21 1999-10-28 Yissum Res Dev Co Determination of an analyte in a liquid medium
IL116921A (en) 1996-01-26 2000-11-21 Yissum Res Dev Co Electrochemical system for determination of an analyte in a liquid medium
US6387707B1 (en) * 1996-04-25 2002-05-14 Bioarray Solutions Array Cytometry
ATE366418T1 (de) 1996-04-25 2007-07-15 Bioarray Solutions Ltd Licht-regulierte, elektrokinetische zusammensetzung von partikeln an oberflächen
US6165335A (en) 1996-04-25 2000-12-26 Pence And Mcgill University Biosensor device and method
KR20000048833A (ko) * 1996-10-07 2000-07-25 둘락 노먼 씨. ｐ53에 대한 항체의 검출을 위한 검정법
US7014992B1 (en) 1996-11-05 2006-03-21 Clinical Micro Sensors, Inc. Conductive oligomers attached to electrodes and nucleoside analogs
US7381525B1 (en) 1997-03-07 2008-06-03 Clinical Micro Sensors, Inc. AC/DC voltage apparatus for detection of nucleic acids
US7045285B1 (en) 1996-11-05 2006-05-16 Clinical Micro Sensors, Inc. Electronic transfer moieties attached to peptide nucleic acids
WO1998047001A1 (en) * 1997-04-11 1998-10-22 The University Of New Mexico Modular assembly for reagentless affinity separation and detection of analyte
US6013459A (en) 1997-06-12 2000-01-11 Clinical Micro Sensors, Inc. Detection of analytes using reorganization energy
US7560237B2 (en) * 1997-06-12 2009-07-14 Osmetech Technology Inc. Electronics method for the detection of analytes
CA2311165C (en) * 1997-11-21 2008-08-19 Unilever Plc Improvements in or relating to electrochemical assays
JP3105868B2 (ja) * 1998-08-07 2000-11-06 新潟日本電気株式会社 トナー濃度検出装置及びプログラムを記憶した記憶媒体
US6281006B1 (en) * 1998-08-24 2001-08-28 Therasense, Inc. Electrochemical affinity assay
CA2341379A1 (en) * 1998-09-17 2000-03-23 Clinical Micro Sensors, Inc. Signal detection techniques for the detection of analytes
US6740518B1 (en) 1998-09-17 2004-05-25 Clinical Micro Sensors, Inc. Signal detection techniques for the detection of analytes
AU1241000A (en) 1998-10-27 2000-05-15 Clinical Micro Sensors, Inc. Detection of target analytes using particles and electrodes
US6468657B1 (en) * 1998-12-04 2002-10-22 The Regents Of The University Of California Controllable ion-exchange membranes
US6833267B1 (en) * 1998-12-30 2004-12-21 Clinical Micro Sensors, Inc. Tissue collection devices containing biosensors
WO2000052456A1 (en) 1999-03-02 2000-09-08 Helix Biopharma Corporation Biosensor device and method
US6300141B1 (en) * 1999-03-02 2001-10-09 Helix Biopharma Corporation Card-based biosensor device
DE60041072D1 (de) 1999-07-26 2009-01-22 Clinical Micro Sensors Inc Em nachweis
US6824669B1 (en) 2000-02-17 2004-11-30 Motorola, Inc. Protein and peptide sensors using electrical detection methods
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
DE60117556T2 (de) 2000-06-21 2006-11-02 Bioarray Solutions Ltd. Multianalytische molekularanalyse durch verwendung anwendungsspezifischer zufallspartikelarrays
DE20017268U1 (de) * 2000-10-07 2001-03-29 Dechema Elektrochemische Messzelle zur Bestimmung der Zellzahl und Aktivität von biologischen Systemen
US6835552B2 (en) * 2000-12-14 2004-12-28 The Regents Of The University Of California Impedance measurements for detecting pathogens attached to antibodies
US6887667B2 (en) * 2000-12-28 2005-05-03 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Method and apparatus to identify small variations of biomolecules
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
AU2002365115A1 (en) * 2001-07-20 2003-09-02 North Carolina State University Light addressable electrochemical detection of duplex structures
DE10141691A1 (de) * 2001-08-25 2003-03-13 Friz Biochem Gmbh Verdrängungsassay zur Detektion von Ligat-Ligand-Assoziationsereignissen
US20040002073A1 (en) 2001-10-15 2004-01-01 Li Alice Xiang Multiplexed analysis of polymorphic loci by concurrent interrogation and enzyme-mediated detection
US7074519B2 (en) * 2001-10-26 2006-07-11 The Regents Of The University Of California Molehole embedded 3-D crossbar architecture used in electrochemical molecular memory device
US7687258B1 (en) * 2002-05-20 2010-03-30 Maki Wusi C Direct electric biological agent detector
US7176036B2 (en) * 2002-09-20 2007-02-13 Arrowhead Center, Inc. Electroactive microspheres and methods
US20040108226A1 (en) * 2002-10-28 2004-06-10 Constantin Polychronakos Continuous glucose quantification device and method
AU2003298655A1 (en) 2002-11-15 2004-06-15 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
DE10300521A1 (de) * 2003-01-09 2004-07-22 Siemens Ag Organoresistiver Speicher
US20040180369A1 (en) * 2003-01-16 2004-09-16 North Carolina State University Photothermal detection of nucleic acid hybridization
US20040142405A1 (en) * 2003-01-22 2004-07-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Method of detecting drug resistance
US20040191801A1 (en) * 2003-03-25 2004-09-30 Heeger Alan J. Reagentless, reusable bioelectronic detectors and their use as authentication devices
US8003374B2 (en) * 2003-03-25 2011-08-23 The Regents Of The University Of California Reagentless, reusable, bioelectronic detectors
US7927796B2 (en) 2003-09-18 2011-04-19 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
PT1664722E (pt) 2003-09-22 2011-12-28 Bioarray Solutions Ltd Polielectrólito imobilizado à superfície com grupos funcionais múltiplos capazes de se ligarem covalentemente às biomoléculas
US7563569B2 (en) 2003-10-28 2009-07-21 Michael Seul Optimization of gene expression analysis using immobilized capture probes
ES2533876T3 (es) 2003-10-29 2015-04-15 Bioarray Solutions Ltd Análisis multiplexado de ácidos nucleicos mediante fragmentación de ADN bicatenario
US20100000881A1 (en) * 2003-10-30 2010-01-07 North Carolina State University Electrochemical detection of nucleic acid hybridization
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
AU2004240178A1 (en) * 2004-08-20 2006-03-09 Commonwealth Scientific And Industrial Research Organisation Zwitterionic additives for electrochemical devices
JP2006133137A (ja) * 2004-11-08 2006-05-25 Eiichi Tamiya 被検物質の検出方法
US8486629B2 (en) 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
US7889347B2 (en) 2005-11-21 2011-02-15 Plexera Llc Surface plasmon resonance spectrometer with an actuator driven angle scanning mechanism
US7803542B2 (en) * 2005-11-29 2010-09-28 The Regents Of The University Of California Signal-on architecture for electronic, oligonucleotide-based detectors
US7463358B2 (en) 2005-12-06 2008-12-09 Lumera Corporation Highly stable surface plasmon resonance plates, microarrays, and methods
AU2008279042B2 (en) * 2007-07-26 2014-03-13 Agamatrix, Inc. Electrochemical analyte detection apparatus and method
US8004669B1 (en) 2007-12-18 2011-08-23 Plexera Llc SPR apparatus with a high performance fluid delivery system
ES2517919T3 (es) 2008-09-02 2014-11-04 The Governing Council Of The University Of Toronto Microelectrodos nanoestructurados y dispositivos de biodetección que los incorporan
GB2463115B (en) * 2008-09-08 2013-04-10 Schlumberger Holdings Assemblies for the purification of a reservoir or process fluid
GB2463280B (en) * 2008-09-08 2011-02-02 Schlumberger Holdings Electro-chemical sensor
RU2606852C2 (ru) 2011-01-11 2017-01-10 Дзе Гавернинг Каунсил Оф Дзе Юниверсити Оф Торонто Способ детекции белков
JP6019944B2 (ja) * 2011-12-28 2016-11-02 逢坂　哲彌 糖化合物固定化半導体センシングデバイス及び生物学的物質の検出方法
CN104067131A (zh) 2012-02-10 2014-09-24 美艾利尔瑞士公司 用于确定胰岛素抗性的化验和方法
CZ307792B6 (cs) * 2017-08-23 2019-05-09 Masarykova Univerzita Způsob stanovení přítomnosti analytu v kapalném vzorku a jeho použití
CN112213482B (zh) * 2020-09-30 2021-11-09 同济大学 基于免疫组化空间电化学检测样品中抗原含量的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8328520D0 (en) * 1983-10-25 1983-11-23 Serono Diagnostics Ltd Methods of assay
US4591550A (en) * 1984-03-01 1986-05-27 Molecular Devices Corporation Device having photoresponsive electrode for determining analytes including ligands and antibodies
GB8417301D0 (en) * 1984-07-06 1984-08-08 Serono Diagnostics Ltd Assay
US5114674A (en) * 1987-05-01 1992-05-19 Biotronic Systems Corporation Added array of molecular chains for interfering with electrical fields
US5135876A (en) * 1987-09-24 1992-08-04 University Of Utah Method and apparatus for the regulation of complex binding
US4927502A (en) * 1989-01-31 1990-05-22 Board Of Regents, The University Of Texas Methods and apparatus using galvanic immunoelectrodes
CA2048692A1 (en) * 1989-03-13 1990-09-14 Anthony Guiseppi-Elie Surface functionalized and derivatized conducting polymers and method for producing same
JPH02298855A (ja) * 1989-03-20 1990-12-11 Assoc Univ Inc 固定化酵素とレドックス重合体を用いた電気化学的バイオセンサー
US4964972A (en) * 1989-03-30 1990-10-23 Yeda Research And Development Company Limited Ionic recognition and selective response in self assembling monolayer membranes on electrodes
WO1990012092A1 (de) * 1989-04-04 1990-10-18 Fritz Pittner Verfahren zum immobilisieren von proteinen, peptiden, coenzymen od.dgl. an einem träger
US5198367A (en) * 1989-06-09 1993-03-30 Masuo Aizawa Homogeneous amperometric immunoassay
JPH03170500A (ja) * 1989-11-29 1991-07-24 Fuji Photo Film Co Ltd 感光性色素蛋白質の配向化方法
JPH0795170B2 (ja) * 1990-08-21 1995-10-11 ダイソー株式会社 ポリビオロゲン修飾電極およびその用途
US5541069A (en) * 1992-02-28 1996-07-30 Quidel Corporation Assay having improved dose response curve
IL102930A (en) * 1992-08-25 1997-03-18 Yissum Res Dev Co Electrobiochemical analytical method and electrodes

Also Published As

Publication number Publication date
ATE217966T1 (de) 2002-06-15
IL108726A0 (en) 1994-05-30
DE69526747T2 (de) 2002-10-10
JP3583496B2 (ja) 2004-11-04
EP0668502A2 (de) 1995-08-23
DK0668502T3 (da) 2002-08-19
JPH07301615A (ja) 1995-11-14
EP0668502A3 (de) 1996-02-28
DE69526747D1 (de) 2002-06-27
EP0668502B1 (de) 2002-05-22
ES2177586T3 (es) 2002-12-16
US5942388A (en) 1999-08-24

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