IL107599A0 - Eck receptor ligands - Google Patents

Eck receptor ligands

Info

Publication number
IL107599A0
IL107599A0 IL10759993A IL10759993A IL107599A0 IL 107599 A0 IL107599 A0 IL 107599A0 IL 10759993 A IL10759993 A IL 10759993A IL 10759993 A IL10759993 A IL 10759993A IL 107599 A0 IL107599 A0 IL 107599A0
Authority
IL
Israel
Prior art keywords
eck receptor
eck
disclosed
receptor
receptor ligands
Prior art date
Application number
IL10759993A
Other languages
English (en)
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of IL107599A0 publication Critical patent/IL107599A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
IL10759993A 1992-11-13 1993-11-12 Eck receptor ligands IL107599A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97770892A 1992-11-13 1992-11-13
US14561693A 1993-11-09 1993-11-09

Publications (1)

Publication Number Publication Date
IL107599A0 true IL107599A0 (en) 1994-02-27

Family

ID=26843152

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10759993A IL107599A0 (en) 1992-11-13 1993-11-12 Eck receptor ligands

Country Status (14)

Country Link
US (2) US5650504A (no)
EP (1) EP0597503B1 (no)
JP (1) JPH08505765A (no)
CN (1) CN1094446A (no)
AT (1) ATE172246T1 (no)
AU (1) AU685765B2 (no)
CA (1) CA2149333C (no)
DE (1) DE69321555T2 (no)
DK (1) DK0597503T3 (no)
ES (1) ES2121915T3 (no)
FI (1) FI952328A (no)
IL (1) IL107599A0 (no)
NO (1) NO951861L (no)
WO (1) WO1994011020A1 (no)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8931291A (en) * 1990-10-16 1992-05-20 Regents Of The University Of Michigan, The Cytokine-induced marker for inflammatory response
US5824303A (en) * 1992-11-13 1998-10-20 Amgen Inc. Eck receptor ligands
PT669929E (pt) * 1992-11-13 2007-04-30 Immunex Corp Ligando de elk, uma citoquina
US5516658A (en) * 1993-08-20 1996-05-14 Immunex Corporation DNA encoding cytokines that bind the cell surface receptor hek
US5747033A (en) * 1993-10-28 1998-05-05 Regeneron Pharmaceuticals, Inc. Method of enhancing the biological activity of Eph family ligands
CA2187167A1 (en) * 1994-04-04 1995-10-12 Samuel Davis Biologically active eph family ligands
US6303769B1 (en) 1994-07-08 2001-10-16 Immunex Corporation Lerk-5 dna
DE69532857T2 (de) * 1994-10-27 2005-04-28 Genentech Inc., San Francisco Neurotrophischer AL-1 Faktor, einer Ligand verwandt mit dem EPH Tyrosine Kinase Receptor
US5759775A (en) 1994-10-27 1998-06-02 Genetech, Inc. Methods for detecting nucleic acids encoding AL--1 neurotrophic factor
US6057124A (en) * 1995-01-27 2000-05-02 Amgen Inc. Nucleic acids encoding ligands for HEK4 receptors
US6100346A (en) * 1995-03-06 2000-08-08 Ethicon, Inc. Copolymers of polyoxaamides
US6610296B2 (en) 1995-10-26 2003-08-26 Genentech, Inc. Methods of enhancing cognitive function using an AL-1 neurotrophic factor immunoadhesin
US6887674B1 (en) 1998-04-13 2005-05-03 California Institute Of Technology Artery- and vein-specific proteins and uses therefor
US6864227B1 (en) 1998-04-13 2005-03-08 California Institute Of Technology Artery-and vein-specific proteins and uses therefor
EP1141294B1 (en) 1998-12-23 2005-03-02 Regeneron Pharmaceuticals, Inc. Method of enhancing the biological activity of ligands
US6248725B1 (en) 1999-02-23 2001-06-19 Amgen, Inc. Combinations and methods for promoting in vivo liver cell proliferation and enhancing in vivo liver-directed gene transduction
EP1867719A3 (en) * 1999-06-02 2008-03-19 Genentech, Inc. Methods and compositions for inhibiting neoplastic cell growth
US7192698B1 (en) 1999-08-17 2007-03-20 Purdue Research Foundation EphA2 as a diagnostic target for metastatic cancer
US6927203B1 (en) 1999-08-17 2005-08-09 Purdue Research Foundation Treatment of metastatic disease
US7101976B1 (en) 2000-09-12 2006-09-05 Purdue Research Foundation EphA2 monoclonal antibodies and methods of making and using same
WO2002086460A1 (en) * 2001-04-20 2002-10-31 Consensus Pharmaceuticals, Inc. Methods for identifying ligands of g-protein-coupled receptors
US20050152899A1 (en) * 2002-05-10 2005-07-14 Kinch Michael S. EphA2 agonistic monoclonal antibodies and methods of use thereof
WO2003094859A2 (en) * 2002-05-10 2003-11-20 Medimmune, Inc. Epha2 monoclonal antibodies and methods of use thereof
JP4585968B2 (ja) * 2002-05-10 2010-11-24 パーデュー・リサーチ・ファウンデーション ＥｐｈＡ２アゴニストモノクローナル抗体およびその使用法
AU2003268345A1 (en) 2002-09-24 2004-04-19 The Burnham Institute Novel agents that modulate eph receptor activity
US7381410B2 (en) 2003-03-12 2008-06-03 Vasgene Therapeutics, Inc. Polypeptide compounds for inhibiting angiogenesis and tumor growth
AU2004220525B2 (en) 2003-03-12 2011-03-31 Vasgene Therapeutics, Inc. Nucleic acid compounds for inhibiting angiogenesis and tumor growth
EP1618184A4 (en) * 2003-04-11 2006-06-21 Medimmune Inc EPHA2, HYPOPROLIFERATIVE CELL DISORDERS, AND EPITHELIAL AND ENDOTHELIAL RECONSTITUTION
CA2521594A1 (en) * 2003-04-11 2004-10-28 Medimmune, Inc. Epha2 and non-neoplastic hyperproliferative cell disorders
EP1628992A4 (en) * 2003-05-13 2008-04-16 Novartis Vaccines & Diagnostic METHODS FOR MODULATING METASTASIS AND SKELETAL RELATED EVENTS RESULTING FROM METASTASES
WO2005090406A2 (en) 2004-03-12 2005-09-29 Vasgene Therapeutics, Inc. Antibodies binding to ephb4 for inhibiting angiogenesis and tumor growth
CN102718867A (zh) 2004-03-12 2012-10-10 瓦斯基因治疗公司 结合ephb4、抑制血管发生和肿瘤生长的抗体
EP2301963A1 (en) 2004-09-23 2011-03-30 Vasgene Therapeutics, Inc. Polypeptide compounds for inhibiting angiogenesis and tumor growth
EP1841790B1 (en) 2005-01-27 2010-11-03 The Burnham Institute Ephb receptor-binding peptides
AU2008287427B2 (en) 2007-08-13 2014-10-09 Vasgene Therapeutics, Inc. Cancer treatment using humanized antibodies that bind to EphB4

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL9001052A (nl) * 1990-05-02 1991-12-02 Tno Werkwijze voor het bepalen van een specifiek ligand in een vloeibaar monster met behulp van een evanescent veld, alsook een daarvoor geschikt onderdeel van de benodigde meetinrichting.
AU8931291A (en) * 1990-10-16 1992-05-20 Regents Of The University Of Michigan, The Cytokine-induced marker for inflammatory response

Also Published As

Publication number Publication date
ATE172246T1 (de) 1998-10-15
NO951861D0 (no) 1995-05-11
AU5599794A (en) 1994-06-08
DE69321555T2 (de) 1999-06-24
EP0597503A2 (en) 1994-05-18
NO951861L (no) 1995-07-11
EP0597503A3 (en) 1995-05-24
DE69321555D1 (de) 1998-11-19
US5650504A (en) 1997-07-22
AU685765B2 (en) 1998-01-29
FI952328A0 (fi) 1995-05-12
DK0597503T3 (da) 1999-06-23
ES2121915T3 (es) 1998-12-16
JPH08505765A (ja) 1996-06-25
EP0597503B1 (en) 1998-10-14
CA2149333C (en) 2002-01-22
CN1094446A (zh) 1994-11-02
US5716934A (en) 1998-02-10
WO1994011020A1 (en) 1994-05-26
FI952328A (fi) 1995-07-10
CA2149333A1 (en) 1994-05-26

Similar Documents

Publication Publication Date Title
IL107599A0 (en) Eck receptor ligands
WO1996036713A3 (en) Eck receptor ligands
DK0662827T4 (da) Terapeutiske og diagnostiske fremgangsmåder og sammensætninger baseret på Notch-proteiner og nucleinsyrer
EP1674477A3 (en) Binding polypeptides for B lymphocyte stimulator protein (BLYS)
IL83079A0 (en) Nitrilotriacetic acid derivatives,metal chelate resins prepared therefrom and their use in chromatography
WO1994023030A3 (en) Methods and materials relating to the functional domains of dna binding proteins
AU4470789A (en) Compositions and process for amplyifying and detecting nucleic acid sequences
ZA87141B (en) Dna sequences coding for proteins having the biological activity of husi-type i inhibitors,biotechnological methods for the preparation of said proteins and pharmaceutical compositions containing said proteins
HU892118D0 (en) Process for producing heparing binding proteins dna coding these and pharmaceutical preparatives containing these proteins
IL73569A (en) Dna-sequences encoding modified eglins,vectors containing such dna sequences,hosts transformed by the vectors,modified eglin polypeptides produced by the transformed hosts,methods for the preparation of the dna sequences,vectors and transformed hosts,processes for the preparation of modified eglins utilizing the transformed hosts and pharmaceutical products containing the modified eglins
EP0990703A4 (en) NEW POLYPEPTIDE, FOR CODING DNA AND THEIR USE
DK493988D0 (da) 4-oxo-3-quinolincarboxylsyrer, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende disse forbindelser
DE3790139D2 (en) Antiparatypical antibodies, their use for detecting and treating auto-immune diseases
SG128403A1 (en) Tnf-receptors, tnf binding proteins and dnas coding for them
IL93035A0 (en) Plasminogen activator,dna sequence encoding the amino sequence thereof,process for the preparation thereof and pharmaceutical composition containing the same
DK623089D0 (da) Trombolytiske proteiner, fremgangsmaade til fremstilling deraf og praeparater indeholdende disse forbindelser
DK26591D0 (da) Cytidin-5'-diphosphatalkanoler og -glyceroler, fremgangsmaade til fremstilling heraf og praeparater indeholdende disse forbindelser
IL95220A0 (en) Dithiochrome,an insulinbinding molecule,pharmaceutical compositions containing it and methods for extracting it
AU638682C (en) New limphokines, DNA sequences coding for said limphokines and pharmaceutical compositions containing said limphokines
AU7692987A (en) Reagent kit, its use and diagnostic process for the detection of hpasp(human pancreatic specific protein)
GB8819029D0 (en) Method for detection of harmful substances in solid samples
ATE91156T1 (de) Verfahren zur sequenzanalyse von dna.
IE882662L (en) Dna sequences, recombinant dna molecules for producing¹soluble t4 proteins
DK222390D0 (da) Heparin-bindende proteiner, dna'er, der koder for saadanne proteiner, fremgangsmaade til fremstilling af proteinerne same farmaceutiske praeparater indeholdende disse
PL276089A1 (en) Apparatus for preliminary purifying biological samples