IL106964A - תולדות אלקילאמוניום 1-)3-אמינופיל(-אתאנסולפונאט בעלות פעילות אופטית, הכנתן ושימושיהן - Google Patents
תולדות אלקילאמוניום 1-)3-אמינופיל(-אתאנסולפונאט בעלות פעילות אופטית, הכנתן ושימושיהןInfo
- Publication number
- IL106964A IL106964A IL106964A IL10696493A IL106964A IL 106964 A IL106964 A IL 106964A IL 106964 A IL106964 A IL 106964A IL 10696493 A IL10696493 A IL 10696493A IL 106964 A IL106964 A IL 106964A
- Authority
- IL
- Israel
- Prior art keywords
- alkyl
- radical
- radicals
- optionally substituted
- phenyl
- Prior art date
Links
- -1 alkylammonium 1-(3-aminophenyl)- ethanesulphonate derivatives Chemical class 0.000 title claims 12
- 125000005207 tetraalkylammonium group Chemical group 0.000 claims abstract 4
- 125000005210 alkyl ammonium group Chemical class 0.000 claims abstract 3
- 125000000217 alkyl group Chemical group 0.000 claims 20
- 238000000034 method Methods 0.000 claims 16
- 125000003545 alkoxy group Chemical group 0.000 claims 12
- 125000005843 halogen group Chemical group 0.000 claims 11
- 125000001424 substituent group Chemical group 0.000 claims 11
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical group [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 claims 9
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 8
- 150000001875 compounds Chemical class 0.000 claims 6
- 229910052757 nitrogen Inorganic materials 0.000 claims 6
- 125000003884 phenylalkyl group Chemical group 0.000 claims 5
- 125000004453 alkoxycarbonyl group Chemical group 0.000 claims 4
- 125000004432 carbon atom Chemical group C* 0.000 claims 4
- 238000006243 chemical reaction Methods 0.000 claims 4
- 125000000753 cycloalkyl group Chemical group 0.000 claims 4
- 125000005842 heteroatom Chemical group 0.000 claims 4
- 125000000623 heterocyclic group Chemical group 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 3
- 125000004414 alkyl thio group Chemical group 0.000 claims 3
- 239000012736 aqueous medium Substances 0.000 claims 3
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 claims 3
- 229910052739 hydrogen Inorganic materials 0.000 claims 3
- 239000001257 hydrogen Substances 0.000 claims 3
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 3
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 claims 3
- 229920006395 saturated elastomer Polymers 0.000 claims 3
- 229910052717 sulfur Inorganic materials 0.000 claims 3
- KJZHVIPBHLWHKA-UHFFFAOYSA-M 1-(3-aminophenyl)ethanesulfonate;tetrabutylazanium Chemical compound [O-]S(=O)(=O)C(C)C1=CC=CC(N)=C1.CCCC[N+](CCCC)(CCCC)CCCC KJZHVIPBHLWHKA-UHFFFAOYSA-M 0.000 claims 2
- UKCVLVFFCZYWMH-UHFFFAOYSA-N OS(=O)(=O)C(C)C1=CC=CC([N+]([O-])=O)=C1 Chemical compound OS(=O)(=O)C(C)C1=CC=CC([N+]([O-])=O)=C1 UKCVLVFFCZYWMH-UHFFFAOYSA-N 0.000 claims 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 2
- 150000001768 cations Chemical class 0.000 claims 2
- QAOWNCQODCNURD-UHFFFAOYSA-M hydrogensulfate Chemical compound OS([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-M 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 239000012442 inert solvent Substances 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 125000002950 monocyclic group Chemical group 0.000 claims 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 2
- 125000003367 polycyclic group Chemical group 0.000 claims 2
- 229910052700 potassium Inorganic materials 0.000 claims 2
- 239000011591 potassium Substances 0.000 claims 2
- 238000011084 recovery Methods 0.000 claims 2
- GEHJYWRUCIMESM-UHFFFAOYSA-L sodium sulfite Chemical compound [Na+].[Na+].[O-]S([O-])=O GEHJYWRUCIMESM-UHFFFAOYSA-L 0.000 claims 2
- 150000005621 tetraalkylammonium salts Chemical class 0.000 claims 2
- IJXJGQCXFSSHNL-QMMMGPOBSA-N (R)-(-)-2-Phenylglycinol Chemical compound OC[C@H](N)C1=CC=CC=C1 IJXJGQCXFSSHNL-QMMMGPOBSA-N 0.000 claims 1
- JYDIJFKNXHPWBJ-FBBRVDCYSA-M (s)-[(2r,4s,5r)-1-benzyl-5-ethenyl-1-azoniabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;chloride Chemical compound [Cl-].C([C@H]([C@H](C1)C=C)C[C@@H]2[C@@H](O)C3=CC=NC4=CC=C(C=C43)OC)C[N+]21CC1=CC=CC=C1 JYDIJFKNXHPWBJ-FBBRVDCYSA-M 0.000 claims 1
- CBTKUSGOSLITSO-UHFFFAOYSA-N 1-(1-bromoethyl)-3-nitrobenzene Chemical compound CC(Br)C1=CC=CC([N+]([O-])=O)=C1 CBTKUSGOSLITSO-UHFFFAOYSA-N 0.000 claims 1
- IJXJGQCXFSSHNL-UHFFFAOYSA-N 2-amino-2-phenylethanol Chemical class OCC(N)C1=CC=CC=C1 IJXJGQCXFSSHNL-UHFFFAOYSA-N 0.000 claims 1
- MWGATWIBSKHFMR-UHFFFAOYSA-N 2-anilinoethanol Chemical compound OCCNC1=CC=CC=C1 MWGATWIBSKHFMR-UHFFFAOYSA-N 0.000 claims 1
- 101100243950 Arabidopsis thaliana PIE1 gene Proteins 0.000 claims 1
- 239000004285 Potassium sulphite Substances 0.000 claims 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 125000004442 acylamino group Chemical group 0.000 claims 1
- 229910052783 alkali metal Inorganic materials 0.000 claims 1
- 150000001340 alkali metals Chemical class 0.000 claims 1
- 125000005078 alkoxycarbonylalkyl group Chemical group 0.000 claims 1
- IYABWNGZIDDRAK-UHFFFAOYSA-N allene Chemical group C=C=C IYABWNGZIDDRAK-UHFFFAOYSA-N 0.000 claims 1
- KCNKJCHARANTIP-SNAWJCMRSA-N allyl-{4-[3-(4-bromo-phenyl)-benzofuran-6-yloxy]-but-2-enyl}-methyl-amine Chemical compound C=1OC2=CC(OC/C=C/CN(CC=C)C)=CC=C2C=1C1=CC=C(Br)C=C1 KCNKJCHARANTIP-SNAWJCMRSA-N 0.000 claims 1
- 125000002490 anilino group Chemical group [H]N(*)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 239000003054 catalyst Substances 0.000 claims 1
- JEVCWSUVFOYBFI-UHFFFAOYSA-N cyanyl Chemical compound N#[C] JEVCWSUVFOYBFI-UHFFFAOYSA-N 0.000 claims 1
- 125000000000 cycloalkoxy group Chemical group 0.000 claims 1
- 125000005112 cycloalkylalkoxy group Chemical group 0.000 claims 1
- 125000004663 dialkyl amino group Chemical group 0.000 claims 1
- 125000005117 dialkylcarbamoyl group Chemical group 0.000 claims 1
- 150000004820 halides Chemical class 0.000 claims 1
- 238000005984 hydrogenation reaction Methods 0.000 claims 1
- 125000003392 indanyl group Chemical group C1(CCC2=CC=CC=C12)* 0.000 claims 1
- 125000005956 isoquinolyl group Chemical group 0.000 claims 1
- HZVOZRGWRWCICA-UHFFFAOYSA-N methanediyl Chemical group [CH2] HZVOZRGWRWCICA-UHFFFAOYSA-N 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 125000002911 monocyclic heterocycle group Chemical group 0.000 claims 1
- 229910000402 monopotassium phosphate Inorganic materials 0.000 claims 1
- 235000019796 monopotassium phosphate Nutrition 0.000 claims 1
- 125000001624 naphthyl group Chemical group 0.000 claims 1
- 125000002071 phenylalkoxy group Chemical group 0.000 claims 1
- PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 claims 1
- 125000004585 polycyclic heterocycle group Chemical group 0.000 claims 1
- BHZRJJOHZFYXTO-UHFFFAOYSA-L potassium sulfite Chemical compound [K+].[K+].[O-]S([O-])=O BHZRJJOHZFYXTO-UHFFFAOYSA-L 0.000 claims 1
- 235000019252 potassium sulphite Nutrition 0.000 claims 1
- LVTHXRLARFLXNR-UHFFFAOYSA-M potassium;1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate Chemical compound [K+].[O-]S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F LVTHXRLARFLXNR-UHFFFAOYSA-M 0.000 claims 1
- HEWDQCXPUMDFCY-UHFFFAOYSA-M potassium;1-(3-nitrophenyl)ethanesulfonate Chemical compound [K+].[O-]S(=O)(=O)C(C)C1=CC=CC([N+]([O-])=O)=C1 HEWDQCXPUMDFCY-UHFFFAOYSA-M 0.000 claims 1
- 125000004076 pyridyl group Chemical group 0.000 claims 1
- 125000005493 quinolyl group Chemical group 0.000 claims 1
- 125000001567 quinoxalinyl group Chemical group N1=C(C=NC2=CC=CC=C12)* 0.000 claims 1
- 238000000926 separation method Methods 0.000 claims 1
- 235000010265 sodium sulphite Nutrition 0.000 claims 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-L sulfite Chemical compound [O-]S([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-L 0.000 claims 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 1
- CCIVGXIOQKPBKL-UHFFFAOYSA-N ethanesulfonic acid Chemical class CCS(O)(=O)=O CCIVGXIOQKPBKL-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/24—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of a carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9210840A FR2695640B1 (fr) | 1992-09-11 | 1992-09-11 | Dérivés d'(amino-3 phényl)-1 éthanesulfonate d'alkylammonium optiquement actifs, leur préparation et leur utilisation. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL106964A0 IL106964A0 (en) | 1993-12-28 |
| IL106964A true IL106964A (he) | 1998-02-22 |
Family
ID=9433406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL106964A IL106964A (he) | 1992-09-11 | 1993-09-09 | תולדות אלקילאמוניום 1-)3-אמינופיל(-אתאנסולפונאט בעלות פעילות אופטית, הכנתן ושימושיהן |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5523469A (he) |
| EP (1) | EP0659175B1 (he) |
| JP (1) | JPH08503930A (he) |
| KR (1) | KR950703521A (he) |
| AT (1) | ATE156808T1 (he) |
| AU (1) | AU666585B2 (he) |
| CA (1) | CA2144159A1 (he) |
| DE (1) | DE69313122T2 (he) |
| DK (1) | DK0659175T3 (he) |
| ES (1) | ES2105314T3 (he) |
| FR (1) | FR2695640B1 (he) |
| GR (1) | GR3024607T3 (he) |
| HU (1) | HUT71624A (he) |
| IL (1) | IL106964A (he) |
| NO (1) | NO950724D0 (he) |
| NZ (1) | NZ255452A (he) |
| RU (1) | RU95112487A (he) |
| WO (1) | WO1994006760A1 (he) |
| ZA (1) | ZA936604B (he) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2695643B1 (fr) * | 1992-09-11 | 1994-11-25 | Rhone Poulenc Rorer Sa | Dérivés d'uréido-acétamide, leur préparation et les médicaments les contenant. |
| KR100390578B1 (ko) | 1998-12-17 | 2003-12-18 | 제일모직주식회사 | 고굴절율 전도성 고분자 박막 투명 필름 코팅액 조성물 |
| US20030105352A1 (en) * | 2001-08-03 | 2003-06-05 | Dado Gregory P. | Arylalkylsulfonic acids and methods for producing same |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7204697A (he) * | 1971-04-10 | 1972-10-12 | ||
| DE2117462A1 (de) * | 1971-04-10 | 1972-10-26 | Farbenfabfiken Bayer AG, 5090 Lever kusen | Disazofarbstoffe |
| FR2667864B2 (fr) * | 1990-03-07 | 1994-08-05 | Rhone Poulenc Sante | Derives de n-phenyl glycinamides, leur preparation et les medicaments les contenant. |
-
1992
- 1992-09-11 FR FR9210840A patent/FR2695640B1/fr not_active Expired - Fee Related
-
1993
- 1993-09-06 DK DK93919420.5T patent/DK0659175T3/da active
- 1993-09-06 AU AU49657/93A patent/AU666585B2/en not_active Ceased
- 1993-09-06 KR KR1019950700904A patent/KR950703521A/ko not_active Withdrawn
- 1993-09-06 JP JP6507840A patent/JPH08503930A/ja active Pending
- 1993-09-06 WO PCT/FR1993/000849 patent/WO1994006760A1/fr not_active Ceased
- 1993-09-06 DE DE69313122T patent/DE69313122T2/de not_active Expired - Fee Related
- 1993-09-06 ES ES93919420T patent/ES2105314T3/es not_active Expired - Lifetime
- 1993-09-06 EP EP93919420A patent/EP0659175B1/fr not_active Expired - Lifetime
- 1993-09-06 AT AT93919420T patent/ATE156808T1/de not_active IP Right Cessation
- 1993-09-06 US US08/397,045 patent/US5523469A/en not_active Expired - Fee Related
- 1993-09-06 NZ NZ255452A patent/NZ255452A/en unknown
- 1993-09-06 HU HU9500708A patent/HUT71624A/hu unknown
- 1993-09-06 RU RU95112487/04A patent/RU95112487A/ru unknown
- 1993-09-06 CA CA002144159A patent/CA2144159A1/fr not_active Abandoned
- 1993-09-08 ZA ZA936604A patent/ZA936604B/xx unknown
- 1993-09-09 IL IL106964A patent/IL106964A/he not_active IP Right Cessation
-
1995
- 1995-02-24 NO NO950724A patent/NO950724D0/no unknown
-
1997
- 1997-09-03 GR GR970400583T patent/GR3024607T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK0659175T3 (da) | 1998-03-16 |
| HUT71624A (en) | 1996-01-29 |
| JPH08503930A (ja) | 1996-04-30 |
| ATE156808T1 (de) | 1997-08-15 |
| HU9500708D0 (en) | 1995-05-29 |
| EP0659175B1 (fr) | 1997-08-13 |
| ES2105314T3 (es) | 1997-10-16 |
| DE69313122T2 (de) | 1998-01-22 |
| ZA936604B (en) | 1996-02-09 |
| FR2695640A1 (fr) | 1994-03-18 |
| CA2144159A1 (fr) | 1994-03-31 |
| NO950724L (no) | 1995-02-24 |
| GR3024607T3 (en) | 1997-12-31 |
| IL106964A0 (en) | 1993-12-28 |
| AU666585B2 (en) | 1996-02-15 |
| WO1994006760A1 (fr) | 1994-03-31 |
| NZ255452A (en) | 1996-05-28 |
| FR2695640B1 (fr) | 1994-11-25 |
| RU95112487A (ru) | 1997-01-10 |
| US5523469A (en) | 1996-06-04 |
| EP0659175A1 (fr) | 1995-06-28 |
| DE69313122D1 (de) | 1997-09-18 |
| KR950703521A (ko) | 1995-09-20 |
| NO950724D0 (no) | 1995-02-24 |
| AU4965793A (en) | 1994-04-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| RH | Patent void |