IL106737A0 - Indole and indoline derivatives, process for their preparation and use as medicament - Google Patents

Indole and indoline derivatives, process for their preparation and use as medicament

Info

Publication number
IL106737A0
IL106737A0 IL10673793A IL10673793A IL106737A0 IL 106737 A0 IL106737 A0 IL 106737A0 IL 10673793 A IL10673793 A IL 10673793A IL 10673793 A IL10673793 A IL 10673793A IL 106737 A0 IL106737 A0 IL 106737A0
Authority
IL
Israel
Prior art keywords
indole
medicament
preparation
indoline derivatives
indoline
Prior art date
Application number
IL10673793A
Other languages
English (en)
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929217674A external-priority patent/GB9217674D0/en
Priority claimed from GB939306461A external-priority patent/GB9306461D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of IL106737A0 publication Critical patent/IL106737A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)
IL10673793A 1992-08-20 1993-08-19 Indole and indoline derivatives, process for their preparation and use as medicament IL106737A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929217674A GB9217674D0 (en) 1992-08-20 1992-08-20 Novel compounds
GB939306461A GB9306461D0 (en) 1993-03-29 1993-03-29 Novel compounds

Publications (1)

Publication Number Publication Date
IL106737A0 true IL106737A0 (en) 1994-05-30

Family

ID=26301461

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10673793A IL106737A0 (en) 1992-08-20 1993-08-19 Indole and indoline derivatives, process for their preparation and use as medicament

Country Status (13)

Country Link
EP (1) EP0656003A1 (zh)
JP (1) JPH08500580A (zh)
CN (1) CN1086819A (zh)
AP (1) AP9300560A0 (zh)
AU (1) AU4704693A (zh)
CA (1) CA2142721A1 (zh)
IL (1) IL106737A0 (zh)
MA (1) MA22955A1 (zh)
MX (1) MX9305037A (zh)
NZ (1) NZ254785A (zh)
SI (1) SI9300438A (zh)
TW (1) TW248557B (zh)
WO (1) WO1994004533A1 (zh)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9306460D0 (en) * 1993-03-29 1993-05-19 Smithkline Beecham Plc Novel compounds
GB9313913D0 (en) * 1993-07-06 1993-08-18 Smithkline Beecham Plc Novel compounds
GB9402542D0 (en) * 1994-02-10 1994-04-06 Smith Kline Beecham Plc Novel compounds
JPH09512025A (ja) * 1994-04-23 1997-12-02 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー ５ｈｔ▲下２ｃ▼および５ｈｔ▲下２ｂ▼アンタゴニストとしての三環式誘導体
GB9420521D0 (en) * 1994-10-12 1994-11-30 Smithkline Beecham Plc Novel compounds
GB9420999D0 (en) * 1994-10-18 1994-12-07 Smithkline Beecham Plc Novel compounds
BR9607016A (pt) * 1995-02-02 1997-10-28 Smithkline Beecham Plc Derivados de indol como antagonísta de receptor 5-ht
JPH10513443A (ja) * 1995-02-02 1998-12-22 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー ５ＨＴ▲下２ｃ▼レセプターアンタゴニスト活性を有する複素環化合物
GB9517559D0 (en) * 1995-08-26 1995-10-25 Smithkline Beecham Plc Novel compounds
GB9607219D0 (en) * 1996-04-04 1996-06-12 Smithkline Beecham Plc Novel compounds
GB9612883D0 (en) 1996-06-20 1996-08-21 Smithkline Beecham Plc Novel compounds
GB9612885D0 (en) * 1996-06-20 1996-08-21 Smithkline Beecham Plc Novel compounds
JP2001508767A (ja) * 1996-12-02 2001-07-03 藤沢薬品工業株式会社 ５―ｈｔ拮抗作用を有するインドール―ウレア誘導体
GB9724372D0 (en) * 1997-11-18 1998-01-14 Smithkline Beecham Plc Novel compounds
UA77650C2 (en) 1999-12-06 2007-01-15 Lundbeck & Co As H Use of serotonin reuptake inhibitor in combination with deramcyclane
FR2807754A1 (fr) * 2000-04-13 2001-10-19 Adir Nouveaux derives de cyclobuta-indole carboxamide, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2837823B1 (fr) * 2002-03-27 2005-04-08 Servier Lab Nouveaux derives d'indoline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
AU2003290009A1 (en) * 2002-12-23 2004-07-14 Bayer Healthcare Ag Diagnostics and therapeutics for diseases assosciated with 5-hydroxytryptamine (serotonin) receptor 2b (5-hteb)
GB0305553D0 (en) * 2003-03-11 2003-04-16 Glaxo Group Ltd Compounds
WO2014049153A1 (en) * 2012-09-28 2014-04-03 INSERM (Institut National de la Santé et de la Recherche Médicale) Antagonists of the 5-ht2b receptor for use in the prevention or treatment of spasticity
US20230312562A1 (en) * 2020-07-02 2023-10-05 Purdue Research Foundation Tetrahydro-3h-pyrazolo quinolone and tetrahydro-3h-pyrrolo[3,2-f]quinoline -containing compounds and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR930702334A (ko) * 1990-09-13 1993-09-08 데이비드 로버트 5 하이드록시트립타민 수용체 길항제로서의 인돌우레아

Also Published As

Publication number Publication date
CA2142721A1 (en) 1994-03-03
NZ254785A (en) 1995-09-26
WO1994004533A1 (en) 1994-03-03
AU4704693A (en) 1994-03-15
CN1086819A (zh) 1994-05-18
TW248557B (zh) 1995-06-01
JPH08500580A (ja) 1996-01-23
EP0656003A1 (en) 1995-06-07
SI9300438A (en) 1994-03-31
MX9305037A (es) 1994-03-31
AP9300560A0 (en) 1995-02-19
MA22955A1 (fr) 1994-04-01

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