IL106732A0 - Human interleukin-13 - Google Patents

Human interleukin-13

Info

Publication number
IL106732A0
IL106732A0 IL106732A IL10673293A IL106732A0 IL 106732 A0 IL106732 A0 IL 106732A0 IL 106732 A IL106732 A IL 106732A IL 10673293 A IL10673293 A IL 10673293A IL 106732 A0 IL106732 A0 IL 106732A0
Authority
IL
Israel
Prior art keywords
human interleukin
interleukin
human
Prior art date
Application number
IL106732A
Other languages
English (en)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/012,543 external-priority patent/US5596072A/en
Application filed by Schering Corp filed Critical Schering Corp
Publication of IL106732A0 publication Critical patent/IL106732A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5437—IL-13
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/23—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a GST-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL106732A 1992-08-21 1993-08-19 Human interleukin-13 IL106732A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US93341692A 1992-08-21 1992-08-21
US1097793A 1993-01-29 1993-01-29
US08/012,543 US5596072A (en) 1992-08-21 1993-02-01 Method of refolding human IL-13

Publications (1)

Publication Number Publication Date
IL106732A0 true IL106732A0 (en) 1993-12-08

Family

ID=27359336

Family Applications (1)

Application Number Title Priority Date Filing Date
IL106732A IL106732A0 (en) 1992-08-21 1993-08-19 Human interleukin-13

Country Status (6)

Country Link
EP (1) EP0656947A1 (fr)
JP (1) JPH07508179A (fr)
AU (1) AU5010793A (fr)
CA (1) CA2142860A1 (fr)
IL (1) IL106732A0 (fr)
WO (1) WO1994004680A1 (fr)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4303315B2 (ja) 1994-05-09 2009-07-29 オックスフォード バイオメディカ（ユーケー）リミテッド 非交差性レトロウイルスベクター
US5614191A (en) * 1995-03-15 1997-03-25 The United States Of America As Represented By The Department Of Health And Human Services IL-13 receptor specific chimeric proteins and uses thereof
US6518061B1 (en) 1995-03-15 2003-02-11 The United States Of America As Represented By The Department Of Health And Human Services IL-13 receptor specific chimeric proteins and uses thereof
US6428788B1 (en) 1995-03-15 2002-08-06 Penn State University Compositions and methods for specifically targeting tumors
US5830453A (en) * 1995-05-19 1998-11-03 Emory University Use of IL-13 to induce 15-lipoxygenase
US6664227B1 (en) 1996-03-01 2003-12-16 Genetics Institute, Llc Treatment of fibrosis by antagonism of IL-13 and IL-13 receptor chains
US5710023A (en) * 1996-03-01 1998-01-20 Genetics Institute, Inc. IL-13 cytokine receptor chain
US7078494B1 (en) 1996-03-01 2006-07-18 Genetics Institute, Llc Antibodies to human IL-13bc and methods of their use in inhibiting IL-13 binding
WO1998010638A1 (fr) * 1996-09-10 1998-03-19 Amrad Operations Pty. Ltd. Molecules d'interet therapeutique
US7070771B1 (en) * 1996-12-09 2006-07-04 Regents Of The University Of California Methods of expressing chimeric mouse and human CD40 ligand in human CD40+ cells
US6171856B1 (en) 1997-07-30 2001-01-09 Board Of Regents, The University Of Texas System Methods and compositions relating to no-mediated cytotoxicity
WO1999006059A2 (fr) * 1997-07-30 1999-02-11 Board Of Regents, The University Of Texas System Procedes et compositions relatifs a la cytotoxicite induite par l'oxyde nitrique
WO1999061618A2 (fr) 1998-05-29 1999-12-02 Heska Corporation Proteines et molecules d'acide nucleique immunoregulatrices du chien et du chat et leurs utilisations
USRE40374E1 (en) 1998-05-29 2008-06-10 Heska Corporation Canine IL-13 immunoregulatory proteins and uses thereof
US6482403B1 (en) * 1998-05-29 2002-11-19 Heska Corporation Caniney IL-13 immunoregulatory proteins and uses thereof
NZ512942A (en) 1998-12-14 2004-01-30 Univ Johns Hopkins Polynucleotides encoding the IL-13 binding chains of the interleukin receptor, pharmaceutical compositions comprising the protein and methods of identifying inhibitors
US7553487B2 (en) 1998-12-14 2009-06-30 Genetics Institute, Llc Method and compositions for treating asthma
NZ525421A (en) * 1998-12-23 2004-10-29 Univ Sydney Method of treating cancer by determining the presence of the disease condition using an assay to determine the binding pattern of immobilised immunoglobulins
GB0004016D0 (en) * 2000-02-22 2000-04-12 Royal Brompton Hospital Biological material and uses thereof
JP2004537500A (ja) * 2000-10-20 2004-12-16 ジェネティクス インスティテュート，エルエルシー 腫瘍の増殖の阻害および免疫応答の増強のための方法および組成物
CA2450147A1 (fr) * 2001-06-07 2002-12-19 Wyeth Structure de solution d'il-13 et utilisation de celle-ci
US7786282B2 (en) 2001-12-06 2010-08-31 The Regents Of The University Of California Nucleic acid molecules encoding TNF-α ligand polypeptides having a CD154 domain
US7495090B2 (en) 2002-05-23 2009-02-24 The Regents Of The University Of California Nucleic acids encoding chimeric CD154 polypeptides
EP1587534A1 (fr) * 2003-01-17 2005-10-26 Children's Hospital Medical Center Traitement des allergies a base de tff2 ou d'un agent l'induisant
MXPA06000258A (es) * 2003-07-15 2006-07-03 Cambridge Antibody Tech Moleculas de anticuerpo humano para interleucina-13.
GB0407315D0 (en) * 2003-07-15 2004-05-05 Cambridge Antibody Tech Human antibody molecules
AU2004308494B2 (en) 2003-12-23 2010-03-18 Genentech, Inc. Novel anti-IL 13 antibodies and uses thereof
US7501121B2 (en) 2004-06-17 2009-03-10 Wyeth IL-13 binding agents
AR049390A1 (es) 2004-06-09 2006-07-26 Wyeth Corp Anticuerpos contra la interleuquina-13 humana y usos de los mismos
EP1824886B1 (fr) * 2004-11-17 2010-12-22 Amgen Inc. Anticorps monoclonaux entierement humains diriges contre l'il-13
EP2532677A1 (fr) 2005-10-21 2012-12-12 Novartis AG Anticorps humains dirigés contre l'IL -13 et utilisations thérapeutiques
US20100196336A1 (en) 2006-05-23 2010-08-05 Dongsu Park Modified dendritic cells having enhanced survival and immunogenicity and related compositions and methods
MX349810B (es) 2006-09-08 2017-08-14 Abbvie Bahamas Ltd Proteinas de enlace de interleucina-13.
CN105175542B (zh) 2010-12-16 2018-12-18 弗·哈夫曼-拉罗切有限公司 与th2抑制相关的诊断和治疗
EP2850093B1 (fr) 2012-01-27 2019-01-09 The Board of Trustees of the Leland Stanford Junior University Polypeptides d'il-13 thérapeutiques
NZ756749A (en) 2013-09-13 2022-05-27 Genentech Inc Methods and compositions comprising purified recombinant polypeptides
EP4163633A1 (fr) 2013-09-13 2023-04-12 F. Hoffmann-La Roche AG Compositions et méthodes pour détecter et quantifier les protéines des cellules hôtes dans les lignées cellulaires et les produits polypeptidiques recombinants
CN113563478A (zh) 2013-09-24 2021-10-29 梅迪塞纳医疗股份有限公司 白介素-4受体结合融合蛋白及其应用
EP3955955A1 (fr) 2019-04-19 2022-02-23 Synerkine Pharma B.V. Protéine de fusion comprenant de l'il13

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0506574B1 (fr) * 1991-03-29 1995-11-29 Sanofi Protéine à activité de type cytokine, ADN recombinant codant pour cette protéine, cellules et microorganismes transformés

Also Published As

Publication number Publication date
AU5010793A (en) 1994-03-15
EP0656947A1 (fr) 1995-06-14
CA2142860A1 (fr) 1994-03-03
WO1994004680A1 (fr) 1994-03-03
JPH07508179A (ja) 1995-09-14

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