IL105390A0 - 3,4-dihydro-2h-1,2,4-benzothiadiazine-1,1-dioxide-3-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

3,4-dihydro-2h-1,2,4-benzothiadiazine-1,1-dioxide-3-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL105390A0
IL105390A0 IL105390A IL10539093A IL105390A0 IL 105390 A0 IL105390 A0 IL 105390A0 IL 105390 A IL105390 A IL 105390A IL 10539093 A IL10539093 A IL 10539093A IL 105390 A0 IL105390 A0 IL 105390A0
Authority
IL
Israel
Prior art keywords
benzothiadiazine
dihydro
dioxide
preparation
carboxylic acid
Prior art date
Application number
IL105390A
Other languages
English (en)
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR929204612A external-priority patent/FR2690159B1/fr
Priority claimed from FR9211675A external-priority patent/FR2696457B1/fr
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of IL105390A0 publication Critical patent/IL105390A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15—Six-membered rings
    • C07D285/16—Thiadiazines; Hydrogenated thiadiazines
    • C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
    • C07D285/20—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
    • C07D285/22—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D285/24—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06—Peri-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Anesthesiology (AREA)
  • Otolaryngology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL105390A 1992-04-15 1993-04-14 3,4-dihydro-2h-1,2,4-benzothiadiazine-1,1-dioxide-3-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them IL105390A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR929204612A FR2690159B1 (fr) 1992-04-15 1992-04-15 Derives d'acide 3,4-dihydro-2h-1,2,4-benzothiadiazine 1,1-dioxyde-3-carboxylique, leur preparation et les medicaments les contenant.
FR9211675A FR2696457B1 (fr) 1992-10-02 1992-10-02 Dérivés de 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxyde, leur préparation et les médicaments les contenant.

Publications (1)

Publication Number Publication Date
IL105390A0 true IL105390A0 (en) 1993-08-18

Family

ID=26229401

Family Applications (1)

Application Number Title Priority Date Filing Date
IL105390A IL105390A0 (en) 1992-04-15 1993-04-14 3,4-dihydro-2h-1,2,4-benzothiadiazine-1,1-dioxide-3-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them

Country Status (9)

Country Link
EP (1) EP0636124A1 (fi)
JP (1) JPH07505411A (fi)
AU (1) AU3957093A (fi)
CA (1) CA2130096A1 (fi)
FI (1) FI944854A (fi)
HU (1) HUT70955A (fi)
IL (1) IL105390A0 (fi)
NO (1) NO943898L (fi)
WO (1) WO1993021170A1 (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2702150B1 (fr) * 1993-03-03 1995-04-07 Rhone Poulenc Rorer Sa Application de dérivés de 2H-1,2-4-benzothiadiazine-3(4H)-one-1,1-dioxyde comme antagonistes non compétitifs du récepteur NMDA.
FR2710062B1 (fr) * 1993-09-17 1995-12-01 Rhone Poulenc Rorer Sa Dérivés d'acide 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxyde-3-carboxylique, leur préparation et les médicaments les contenant.
WO1998012185A1 (en) * 1996-09-17 1998-03-26 The Regents Of The University Of California Benzothiadiazide derivatives and their use as allosteric up-modulators of the ampa receptor
EP1054877A1 (en) 1998-02-11 2000-11-29 Du Pont Pharmaceuticals Company Novel cyclic sulfonamide derivatives as metalloproteinase inhibitors
US6943159B1 (en) 1998-02-18 2005-09-13 Neurosearch A/S Compounds and their use as positive AMPA receptor modulators
PL342843A1 (en) * 1998-02-18 2001-07-16 Neurosearch As Novel compounds and their use as positive ampa receptor modulators
FR2801587B1 (fr) 1999-11-30 2002-01-11 Adir Nouveaux derives de benzothiadiazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DE10004572A1 (de) * 2000-02-02 2001-08-09 Boehringer Ingelheim Pharma Neue positive allosterische AMPA-Rezeptor Modulatoren (PAARM), Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
FR2833950B1 (fr) * 2001-12-21 2005-12-16 Servier Lab Nouveaux derives de benzothiazine et de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2943342B1 (fr) * 2009-03-20 2011-03-04 Servier Lab Nouveaux derives de benzothiadiazepines,leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
JP6410790B2 (ja) * 2013-03-14 2018-10-24 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー ミトコンドリアアルデヒドデヒドロゲナーゼ−２調節因子およびその使用方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1009013A (en) * 1961-05-23 1965-11-03 Richard Hurmer Benzothiadiazine compounds
ATE102612T1 (de) * 1989-07-13 1994-03-15 Rhone Poulenc Sante 2-imino-3 heterocyclylamino-benzothiazoline, ihre herstellung und sie enthaltende arzneimittel.

Also Published As

Publication number Publication date
HU9402980D0 (en) 1995-02-28
NO943898D0 (no) 1994-10-14
FI944854A0 (fi) 1994-10-14
AU3957093A (en) 1993-11-18
EP0636124A1 (fr) 1995-02-01
FI944854A (fi) 1994-10-14
JPH07505411A (ja) 1995-06-15
NO943898L (no) 1994-10-14
WO1993021170A1 (fr) 1993-10-28
CA2130096A1 (fr) 1993-10-28
HUT70955A (en) 1995-11-28

Similar Documents

Publication Publication Date Title
IL106904A0 (en) Thiazolidine derivatives,their preparation and pharmaceutical compositions containing them
IL104447A0 (en) 1,5-benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them
IL109316A0 (en) 1, 5-benzodiazepine derivatives, their preparation and pharmaceutical compositions containing them
IL105035A0 (en) Substituted pipecolinic acid derivatives,their preparation and pharmaceutical compositions containing them
IL78219A0 (en) N,n'-dialkylguanidino dipeptide derivatives,their preparation and pharmaceutical compositions containing them
PH30439A (en) 3,4-Dihydro-2h-1,4-benz-oxazine derivatives and pharmaceutical compositions containing the same
IL108019A0 (en) Hydroxyiminoalkylindole-carboxylic acid derivatives their preparation and pharmaceutical compositions containing them
IL86798A (en) 2,2-dimethylchroman-3-ol derivatives, their preparation and pharmaceutical compositions containing them
IL115072A0 (en) Substituted 4-phenyl-6-amino-nicotinic acid derivatives their preparation pharmaceutical compositions containing them and their use
GB2143532B (en) 1,-5 benzothiazepine derivatives, their preparation and pharmaceutical compositions containing them
IL104356A0 (en) Benzofuranyl-and thiophenylmethylthio-alkanecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
IL103292A0 (en) Cyclic-substituted imidazolyl-propenoic acid derivatives,their preparation and pharmaceutical compositions containing them
IL105390A0 (en) 3,4-dihydro-2h-1,2,4-benzothiadiazine-1,1-dioxide-3-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
IL110366A0 (en) 1,5-Benzodiazepine derivatives, their preparation and pharmaceutical compositions containing them
IL89035A0 (en) 1,4-benzoxazine and 1,4-benzothiazine derivatives,their preparation and pharmaceutical compositions containing them
IL88002A0 (en) 2,2-dimethylchromene derivatives,their preparation and pharmaceutical compositions containing them
IL103291A0 (en) Imidazolyl-propenoic acid derivatives,their preparation and pharmaceutical compositions containing them
IL90231A0 (en) 1,1-dioxo-cephem-4-carbothiolic acid derivatives,their preparation and pharmaceutical compositions containing them
IL105391A0 (en) 1,2,4-benzothiadiazine-3-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
IL105774A0 (en) Thienothiazine derivatives,their preparation and pharmaceutical compositions containing them
IL108930A0 (en) 2,3-Diamino-3- hydroxycarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them
IL105370A0 (en) Propenoyl-imidazole derivatives,their preparation and pharmaceutical compositions containing them
HUT70031A (en) Alfa, omega-diarylalkane derivatives, their preparation and pharmaceutical compositions containing them
IL106108A0 (en) Imidazolyl-substituted phenylpropionic and cinnamic acid derivatives,their preparation and pharmaceutical compositions containing them
IL104840A0 (en) Sulphonylbenzyl-substituted imidazolylpropenoic acid derivatives,their preparation and pharmaceutical compositions containing them