IL104773A - Naphthalene derivatives, their preparation and pharmaceutical compositions containing them - Google Patents
Naphthalene derivatives, their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL104773A IL104773A IL104773A IL10477393A IL104773A IL 104773 A IL104773 A IL 104773A IL 104773 A IL104773 A IL 104773A IL 10477393 A IL10477393 A IL 10477393A IL 104773 A IL104773 A IL 104773A
- Authority
- IL
- Israel
- Prior art keywords
- group
- preparation
- pharmaceutical compositions
- compositions containing
- naphthalene derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Lubricants (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL120056A IL120056A (en) | 1992-02-20 | 1993-02-18 | History of Naphtali |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4085118A JP3042156B2 (ja) | 1992-02-20 | 1992-02-20 | ナフタレン誘導体、その製法及びその合成中間体 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL104773A0 IL104773A0 (en) | 1993-06-10 |
IL104773A true IL104773A (en) | 1997-07-13 |
Family
ID=13849719
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL120056A IL120056A (en) | 1992-02-20 | 1993-02-18 | History of Naphtali |
IL104773A IL104773A (en) | 1992-02-20 | 1993-02-18 | Naphthalene derivatives, their preparation and pharmaceutical compositions containing them |
IL12005697A IL120056A0 (en) | 1992-02-20 | 1997-01-23 | Naphthalene derivatives |
IL12005797A IL120057A0 (en) | 1992-02-20 | 1997-01-23 | Naphthalene derivatives |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL120056A IL120056A (en) | 1992-02-20 | 1993-02-18 | History of Naphtali |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL12005697A IL120056A0 (en) | 1992-02-20 | 1997-01-23 | Naphthalene derivatives |
IL12005797A IL120057A0 (en) | 1992-02-20 | 1997-01-23 | Naphthalene derivatives |
Country Status (17)
Country | Link |
---|---|
US (1) | US5342941A (sv) |
EP (1) | EP0557016B1 (sv) |
JP (1) | JP3042156B2 (sv) |
KR (1) | KR100199121B1 (sv) |
CN (1) | CN1045435C (sv) |
AT (1) | ATE139528T1 (sv) |
AU (1) | AU658046B2 (sv) |
CA (1) | CA2089906C (sv) |
DE (1) | DE69303191T2 (sv) |
DK (1) | DK0557016T3 (sv) |
ES (1) | ES2090855T3 (sv) |
FI (1) | FI102277B (sv) |
GR (1) | GR3020294T3 (sv) |
HK (1) | HK98997A (sv) |
IL (4) | IL120056A (sv) |
MY (1) | MY108891A (sv) |
TW (1) | TW224458B (sv) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL118469A (en) * | 1995-06-15 | 2000-08-13 | Tanabe Seiyaku Co | Naphthalene derivatives their preparation and intermediates thereof |
ID19155A (id) * | 1996-12-13 | 1998-06-18 | Tanabe Seiyaku Co | Turunan-turunan piridin, pembuatannya dan intermediet untuk pembuatannya |
DE19755480A1 (de) * | 1997-12-13 | 1999-06-24 | Gruenenthal Gmbh | Substituierte heterocyclische Benzocycloalkene und ihre Verwendung als analgetisch wirksame Substanzen |
JPH11209350A (ja) | 1998-01-26 | 1999-08-03 | Eisai Co Ltd | 含窒素複素環誘導体およびその医薬 |
US6465495B1 (en) * | 1998-07-30 | 2002-10-15 | Osi Pharmaceuticals, Inc. | Preparation of pyridone-based phosphotyrosine mimetics and uses thereof |
KR100701904B1 (ko) | 1999-08-21 | 2007-04-02 | 알타나 파마 아게 | Pde 억제제 및 베타 2 아드레날린수용체 작동제의상승적 조합 |
CN1520313A (zh) | 2001-05-23 | 2004-08-11 | ������ҩ��ʽ���� | 一种加速骨折愈合的组合物 |
CA2447618A1 (en) * | 2001-05-23 | 2002-11-28 | Tanabe Seiyaku Co., Ltd. | A composition for regenerative treatment of cartilage disease |
TWI221838B (en) | 2001-08-09 | 2004-10-11 | Tanabe Seiyaku Co | Pyrazinoisoquinoline compound or naphthalene compound |
KR20050115331A (ko) | 2003-04-01 | 2005-12-07 | 어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이. | 불임증 포스포디에스터라제의 억제제 |
TWI339578B (en) | 2004-10-29 | 2011-04-01 | Mitsubishi Tanabe Pharma Corp | Use of a pyridine compound for the preparation of a medicament for the treatment of skin lesions |
AR059898A1 (es) | 2006-03-15 | 2008-05-07 | Janssen Pharmaceutica Nv | Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2 |
WO2007112347A1 (en) | 2006-03-28 | 2007-10-04 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
TW200845978A (en) | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
TW200900065A (en) | 2007-03-07 | 2009-01-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives |
BRPI0816767B8 (pt) | 2007-09-14 | 2021-05-25 | Addex Pharmaceuticals Sa | composto 4-fenil-3,4,5,6-tetra-hidro-2h,1'h-[1,4']bipiridi¬nil-2'-onas 1',3'-dissubstituídas, composição farmacêutica e uso dos mesmos |
ES2439291T3 (es) | 2008-09-02 | 2014-01-22 | Janssen Pharmaceuticals, Inc. | Derivados de 3-azabiciclo[3.1.0]hexilo como moduladores de receptores de glutamato metabotrópicos |
WO2010060589A1 (en) | 2008-11-28 | 2010-06-03 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors |
CN102439008B (zh) | 2009-05-12 | 2015-04-29 | 杨森制药有限公司 | 1,2,4-三唑并[4,3-a]吡啶衍生物及其用于治疗或预防神经和精神病症的用途 |
MY153913A (en) | 2009-05-12 | 2015-04-15 | Janssen Pharmaceuticals Inc | 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
NZ596053A (en) | 2009-05-12 | 2013-05-31 | Janssen Pharmaceuticals Inc | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
ES2536433T3 (es) | 2010-11-08 | 2015-05-25 | Janssen Pharmaceuticals, Inc. | Derivados de 1,2,4-triazolo[4,3-a]piridina y su uso como moduladores alostéricos positivos de receptores mGluR2 |
US8993591B2 (en) | 2010-11-08 | 2015-03-31 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a] pyridine derivatives and their use as positive allosteric modulators of MGLUR2 receptors |
US9271967B2 (en) | 2010-11-08 | 2016-03-01 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
JO3368B1 (ar) | 2013-06-04 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2 |
JO3367B1 (ar) | 2013-09-06 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2 |
DK3096790T3 (da) | 2014-01-21 | 2019-10-07 | Janssen Pharmaceutica Nv | Kombinationer omfattende positive allosteriske modulatorer eller orthosteriske agonister af metabotrop glutamaterg subtype 2-receptor og anvendelse af disse |
DK3431106T3 (da) | 2014-01-21 | 2021-03-15 | Janssen Pharmaceutica Nv | Kombinationer omfattende positive allosteriske modulatorer eller orthosteriske agonister af metabotrop glutamaterg subtype 2-receptor og anvendelse af disse |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA825413B (en) * | 1981-08-26 | 1983-06-29 | Pfizer | Thromboxane synthetase inhibitors, processes for their production, and pharmaceutical compositions comprising them |
US4503061A (en) * | 1983-07-22 | 1985-03-05 | Warner-Lambert Company | Substituted phenyl-pyridinones as cardiotonic agents |
US4661596A (en) * | 1985-02-21 | 1987-04-28 | American Home Products Corporation | Quinolinyl (or pyridinyl) methoxy substituted naphthalene compounds as antiallergic agents |
US4792556A (en) * | 1985-09-09 | 1988-12-20 | Syntex (U.S.A.) Inc. | Naphthalene anti-psoriatic agents |
WO1989003681A1 (en) * | 1987-10-19 | 1989-05-05 | Pfizer Inc. | Substituted tetralins, chromans and related compounds in the treatment of asthma |
GB8809481D0 (en) * | 1988-04-21 | 1988-05-25 | Smith Kline French Lab | Chemical compounds |
DE3837464A1 (de) * | 1988-11-04 | 1990-05-10 | Bayer Ag | (hetero)aryloxynaphthalinderivate, verfahren und neue (hetero)aryloxynaphthylamine zu ihrer herstellung sowie ihre verwendung als herbizide |
GB8916683D0 (en) * | 1989-07-21 | 1989-09-06 | Beecham Group Plc | Novel compounds |
US5182296A (en) * | 1989-10-26 | 1993-01-26 | Tanabe Seiyaky Co., Ltd. | Naphthyloxazolidone derivatives |
IL98526A0 (en) * | 1990-06-18 | 1992-07-15 | Merck & Co Inc | Pyridones,processes for their preparation and pharmaceutical compositions containing them |
US5272170A (en) * | 1990-12-05 | 1993-12-21 | J. Uriach & Cia., S.A. | Tetralones with pharmacological activity |
EP0489300A3 (en) * | 1990-12-05 | 1993-03-17 | J. Uriach & Cia. S.A. | New tetralones with pharmacological activity |
FR2671551B1 (fr) * | 1991-01-15 | 1993-03-12 | Adir | Nouveaux composes de structure aryl triazinique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
RU2059603C1 (ru) * | 1991-05-09 | 1996-05-10 | Хоффманн-Ля Рош АГ | ПРОИЗВОДНЫЕ α -ЗАМЕЩЕННЫХ АРИЛУКСУСНЫХ КИСЛОТ И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ |
-
1992
- 1992-02-20 JP JP4085118A patent/JP3042156B2/ja not_active Expired - Lifetime
-
1993
- 1993-02-11 AU AU32952/93A patent/AU658046B2/en not_active Ceased
- 1993-02-11 EP EP93300998A patent/EP0557016B1/en not_active Expired - Lifetime
- 1993-02-11 AT AT93300998T patent/ATE139528T1/de not_active IP Right Cessation
- 1993-02-11 ES ES93300998T patent/ES2090855T3/es not_active Expired - Lifetime
- 1993-02-11 DK DK93300998.7T patent/DK0557016T3/da active
- 1993-02-11 DE DE69303191T patent/DE69303191T2/de not_active Expired - Fee Related
- 1993-02-18 TW TW082101129A patent/TW224458B/zh active
- 1993-02-18 MY MYPI93000270A patent/MY108891A/en unknown
- 1993-02-18 IL IL120056A patent/IL120056A/en not_active IP Right Cessation
- 1993-02-18 KR KR1019930002269A patent/KR100199121B1/ko not_active IP Right Cessation
- 1993-02-18 FI FI930711A patent/FI102277B/sv active
- 1993-02-18 IL IL104773A patent/IL104773A/xx not_active IP Right Cessation
- 1993-02-19 US US08/019,885 patent/US5342941A/en not_active Expired - Fee Related
- 1993-02-19 CA CA002089906A patent/CA2089906C/en not_active Expired - Fee Related
- 1993-02-20 CN CN93102013A patent/CN1045435C/zh not_active Expired - Fee Related
-
1996
- 1996-06-20 GR GR960401544T patent/GR3020294T3/el unknown
-
1997
- 1997-01-23 IL IL12005697A patent/IL120056A0/xx unknown
- 1997-01-23 IL IL12005797A patent/IL120057A0/xx unknown
- 1997-06-26 HK HK98997A patent/HK98997A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69303191D1 (de) | 1996-07-25 |
CN1075957A (zh) | 1993-09-08 |
MY108891A (en) | 1996-11-30 |
FI102277B1 (sv) | 1998-11-13 |
AU3295293A (en) | 1993-08-26 |
DK0557016T3 (da) | 1996-07-15 |
KR100199121B1 (ko) | 1999-06-15 |
FI930711A (fi) | 1993-08-21 |
AU658046B2 (en) | 1995-03-30 |
IL120056A0 (en) | 1997-04-15 |
US5342941A (en) | 1994-08-30 |
TW224458B (sv) | 1994-06-01 |
KR930017851A (ko) | 1993-09-20 |
CN1045435C (zh) | 1999-10-06 |
CA2089906A1 (en) | 1993-08-21 |
JP3042156B2 (ja) | 2000-05-15 |
IL104773A0 (en) | 1993-06-10 |
ATE139528T1 (de) | 1996-07-15 |
DE69303191T2 (de) | 1996-11-14 |
EP0557016A1 (en) | 1993-08-25 |
ES2090855T3 (es) | 1996-10-16 |
FI930711A0 (fi) | 1993-02-18 |
EP0557016B1 (en) | 1996-06-19 |
HK98997A (en) | 1997-08-08 |
GR3020294T3 (en) | 1996-09-30 |
CA2089906C (en) | 1998-08-18 |
FI102277B (sv) | 1998-11-13 |
IL120057A0 (en) | 1997-04-15 |
JPH05229987A (ja) | 1993-09-07 |
IL120056A (en) | 1998-02-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL104773A (en) | Naphthalene derivatives, their preparation and pharmaceutical compositions containing them | |
TW349098B (en) | Naphthalene derivatives, process for the preparation thereof, and intermediates therefor | |
GEP20002210B (en) | Acridine Derivatives | |
ES8801239A1 (es) | Un procedimiento para la preparacion de derivados de naftaleno | |
EP0168500A4 (en) | PURINE COMBATS, THEIR PRODUCTION AND THE MEDICINAL PRODUCTS CONTAINING THEM. | |
AU591390B2 (en) | Arylcyclobutylalkyl amines and their use as antidepressive medicines | |
ES2072223A1 (es) | Liposomas encapsulando doxorubicina. | |
CA2023311A1 (en) | Furan derivatives | |
GB9315510D0 (en) | Therapeutic heterocyclic derivatives | |
EP0230402A3 (en) | Pharmacologically active alkylol derivatives | |
KR960014780B1 (en) | Dental plaque inhibitor composition and its preparation | |
IL106564A (en) | Tetrahydronaphthalene derivatives their preparation and pharmaceutical compositions containing them | |
NZ222973A (en) | Substituted piperidine and azepine derivatives and pharmaceutical compositions |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
RH1 | Patent not in force |