IL103546A0 - Triazaspirodecanone-methylchromans,their preparation and pharmaceutical compositions containing them - Google Patents
Triazaspirodecanone-methylchromans,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL103546A0 IL103546A0 IL103546A IL10354692A IL103546A0 IL 103546 A0 IL103546 A0 IL 103546A0 IL 103546 A IL103546 A IL 103546A IL 10354692 A IL10354692 A IL 10354692A IL 103546 A0 IL103546 A0 IL 103546A0
- Authority
- IL
- Israel
- Prior art keywords
- methylchromans
- triazaspirodecanone
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 2
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrane Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Photoreceptors In Electrophotography (AREA)
- Cosmetics (AREA)
- Enzymes And Modification Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4135473A DE4135473A1 (de) | 1991-10-28 | 1991-10-28 | Triazaspirodecanon-methylchromane |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL103546A0 true IL103546A0 (en) | 1993-03-15 |
Family
ID=6443565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL103546A IL103546A0 (en) | 1991-10-28 | 1992-10-26 | Triazaspirodecanone-methylchromans,their preparation and pharmaceutical compositions containing them |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6060482A (https=) |
| EP (1) | EP0539803B1 (https=) |
| JP (1) | JP3257708B2 (https=) |
| KR (1) | KR930007945A (https=) |
| AT (1) | ATE175414T1 (https=) |
| AU (1) | AU650792B2 (https=) |
| CA (1) | CA2081256A1 (https=) |
| CZ (1) | CZ322492A3 (https=) |
| DE (2) | DE4135473A1 (https=) |
| DK (1) | DK0539803T3 (https=) |
| ES (1) | ES2125879T3 (https=) |
| FI (1) | FI924848A7 (https=) |
| GR (1) | GR3029450T3 (https=) |
| HU (1) | HUT64068A (https=) |
| IL (1) | IL103546A0 (https=) |
| MX (1) | MX9205869A (https=) |
| NO (1) | NO923974L (https=) |
| TW (1) | TW208010B (https=) |
| ZA (1) | ZA928290B (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19522088A1 (de) * | 1995-06-19 | 1997-01-02 | Bayer Ag | Benzisothiazolyl-substituierte Aminomethylchromane |
| CA2226058C (en) * | 1997-01-30 | 2008-01-29 | F. Hoffmann-La Roche Ag | 8-substituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives |
| US6686370B2 (en) * | 1999-12-06 | 2004-02-03 | Euro-Celtique S.A. | Triazospiro compounds having nociceptin receptor affinity |
| JPWO2003040382A1 (ja) * | 2001-11-09 | 2005-03-03 | 株式会社カネカ | 光学活性クロマン誘導体の製造法および中間体 |
| US6995168B2 (en) | 2002-05-31 | 2006-02-07 | Euro-Celtique S.A. | Triazaspiro compounds useful for treating or preventing pain |
| JP4712384B2 (ja) * | 2002-09-09 | 2011-06-29 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Ｏｒｌ−１受容体介在障害の治療に有用なヒドロキシアルキル置換１，３，８−トリアザスピロ［４．５］デカン−４−オン誘導体 |
| US20070229303A1 (en) * | 2003-10-16 | 2007-10-04 | Collier Willliam R | Fluid Level Detector and Alarm Apparatus |
| US20060178390A1 (en) * | 2004-08-02 | 2006-08-10 | Alfonzo Jordan | 1,3,8-Triazaspiro[4,5]decan-4-one derivatives useful for the treatment of ORL-1 receptor mediated disorders |
| US8703948B2 (en) * | 2006-11-28 | 2014-04-22 | Janssen Pharmaceutica Nv | Salts of 3-(3-amino-2-(R)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl)-1,3,8-triaza-spiro[4.5]decan-4-one |
| CA2683598C (en) * | 2007-04-09 | 2015-11-17 | Janssen Pharmaceutica Nv | 1,3,8-trisubstituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as ligands of the orl-i receptor for the treatment of anxiety and depression |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3826835A (en) * | 1971-01-08 | 1974-07-30 | Ciba Geigy Corp | 8-benzofurylmethyl-1,3,8-triazaspiro(4,5)decanes as neuroleptics |
| US4749702A (en) * | 1985-04-15 | 1988-06-07 | Janssen Pharmaceutica N. V. | Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines |
| US4826848A (en) * | 1985-04-15 | 1989-05-02 | Janssen Pharmaceutica N.V. | Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines |
| US4689330A (en) * | 1985-04-15 | 1987-08-25 | Janssen Pharmaceutica N.V. | Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines |
| US4957928A (en) * | 1986-06-26 | 1990-09-18 | Ciba-Geigy Corporation | Hydrogenated 1-benzooxacycloalkylpyridinecarboxylic acid compounds |
| DE3901814A1 (de) * | 1988-07-28 | 1990-02-01 | Bayer Ag | Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga |
| DE3831888A1 (de) * | 1988-09-20 | 1990-03-29 | Troponwerke Gmbh & Co Kg | Arzneimittel zur behandlung von apoplexia cerebri |
| DE4039631A1 (de) * | 1990-12-12 | 1992-06-17 | Troponwerke Gmbh & Co Kg | Neuroprotektive kombination |
-
1991
- 1991-10-28 DE DE4135473A patent/DE4135473A1/de not_active Withdrawn
-
1992
- 1992-09-26 TW TW081107641A patent/TW208010B/zh active
- 1992-10-07 AU AU26265/92A patent/AU650792B2/en not_active Ceased
- 1992-10-13 NO NO92923974A patent/NO923974L/no unknown
- 1992-10-13 MX MX9205869A patent/MX9205869A/es unknown
- 1992-10-15 EP EP92117606A patent/EP0539803B1/de not_active Expired - Lifetime
- 1992-10-15 ES ES92117606T patent/ES2125879T3/es not_active Expired - Lifetime
- 1992-10-15 DK DK92117606T patent/DK0539803T3/da active
- 1992-10-15 AT AT92117606T patent/ATE175414T1/de not_active IP Right Cessation
- 1992-10-15 DE DE59209607T patent/DE59209607D1/de not_active Expired - Fee Related
- 1992-10-19 US US07/963,165 patent/US6060482A/en not_active Expired - Fee Related
- 1992-10-23 CA CA002081256A patent/CA2081256A1/en not_active Abandoned
- 1992-10-26 FI FI924848A patent/FI924848A7/fi unknown
- 1992-10-26 CZ CS923224A patent/CZ322492A3/cs unknown
- 1992-10-26 IL IL103546A patent/IL103546A0/xx unknown
- 1992-10-27 ZA ZA928290A patent/ZA928290B/xx unknown
- 1992-10-27 KR KR1019920019792A patent/KR930007945A/ko not_active Withdrawn
- 1992-10-28 JP JP31279892A patent/JP3257708B2/ja not_active Expired - Fee Related
- 1992-10-28 HU HU9203382A patent/HUT64068A/hu unknown
-
1999
- 1999-02-19 GR GR990400535T patent/GR3029450T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR930007945A (ko) | 1993-05-20 |
| NO923974L (no) | 1993-04-29 |
| GR3029450T3 (en) | 1999-05-28 |
| AU2626592A (en) | 1993-04-29 |
| ES2125879T3 (es) | 1999-03-16 |
| MX9205869A (es) | 1993-04-01 |
| DE4135473A1 (de) | 1993-04-29 |
| FI924848A0 (fi) | 1992-10-26 |
| HU9203382D0 (en) | 1993-01-28 |
| ZA928290B (en) | 1993-05-04 |
| DK0539803T3 (da) | 1999-08-30 |
| ATE175414T1 (de) | 1999-01-15 |
| CA2081256A1 (en) | 1993-04-29 |
| CZ322492A3 (en) | 1993-07-14 |
| JPH05222040A (ja) | 1993-08-31 |
| US6060482A (en) | 2000-05-09 |
| EP0539803B1 (de) | 1999-01-07 |
| FI924848A7 (fi) | 1993-04-29 |
| NO923974D0 (no) | 1992-10-13 |
| DE59209607D1 (de) | 1999-02-18 |
| HUT64068A (en) | 1993-11-29 |
| AU650792B2 (en) | 1994-06-30 |
| JP3257708B2 (ja) | 2002-02-18 |
| EP0539803A1 (de) | 1993-05-05 |
| TW208010B (https=) | 1993-06-21 |
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