IL102494A0 - Platelet activating factor antagonists - Google Patents
Platelet activating factor antagonistsInfo
- Publication number
- IL102494A0 IL102494A0 IL102494A IL10249492A IL102494A0 IL 102494 A0 IL102494 A0 IL 102494A0 IL 102494 A IL102494 A IL 102494A IL 10249492 A IL10249492 A IL 10249492A IL 102494 A0 IL102494 A0 IL 102494A0
- Authority
- IL
- Israel
- Prior art keywords
- pct
- pyrrolo
- pyridin
- carbonyl
- paf
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Radiology & Medical Imaging (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73168191A | 1991-07-17 | 1991-07-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL102494A0 true IL102494A0 (en) | 1993-01-14 |
Family
ID=24940541
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL102494A IL102494A0 (en) | 1991-07-17 | 1992-07-14 | Platelet activating factor antagonists |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5459152A (pt) |
| EP (1) | EP0595924B1 (pt) |
| JP (1) | JP3135917B2 (pt) |
| KR (1) | KR100251603B1 (pt) |
| AT (1) | ATE178796T1 (pt) |
| AU (1) | AU651243B2 (pt) |
| CA (1) | CA2112562A1 (pt) |
| DE (1) | DE69228932T2 (pt) |
| DK (1) | DK0595924T3 (pt) |
| ES (1) | ES2131530T3 (pt) |
| GR (1) | GR3030208T3 (pt) |
| IE (1) | IE922293A1 (pt) |
| IL (1) | IL102494A0 (pt) |
| PT (1) | PT100698B (pt) |
| WO (1) | WO1993001813A1 (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5486525A (en) * | 1993-12-16 | 1996-01-23 | Abbott Laboratories | Platelet activating factor antagonists: imidazopyridine indoles |
| US5567711A (en) * | 1995-04-19 | 1996-10-22 | Abbott Laboratories | Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists |
| US6630496B1 (en) | 1996-08-26 | 2003-10-07 | Genetics Institute Llc | Inhibitors of phospholipase enzymes |
| US6828344B1 (en) | 1998-02-25 | 2004-12-07 | Genetics Institute, Llc | Inhibitors of phospholipase enzymes |
| US6916841B2 (en) * | 1998-02-25 | 2005-07-12 | Genetics Institute, Llc | Inhibitors of phospholipase enzymes |
| US6500853B1 (en) | 1998-02-28 | 2002-12-31 | Genetics Institute, Llc | Inhibitors of phospholipase enzymes |
| WO2001012600A1 (en) * | 1999-08-12 | 2001-02-22 | Cor Therapeutics, Inc. | INHIBITORS OF FACTOR Xa |
| DE10004157A1 (de) * | 2000-02-01 | 2001-08-02 | Merckle Gmbh Chem Pharm Fabrik | 4-Pyridyl-und 2,4-Pyrimidinyl-substituierte Pyrrolderivate und ihre Anwendung in der Pharmazie |
| US20130178453A1 (en) * | 2010-02-09 | 2013-07-11 | Ironwood Pharmaceuticals, Inc. | Cannabinoid Agonists |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2541280B1 (fr) * | 1983-01-13 | 1985-06-21 | Rhone Poulenc Sante | Nouveaux derives du 1h, 3h-pyrrolo (1,2c) thiazolecarboxamide-7, leur preparation et les medicaments qui les contiennent |
| FR2617484B1 (fr) * | 1987-07-02 | 1989-10-20 | Rhone Poulenc Sante | Procede de preparation de l'acide (pyridyl-3)-3 1h-3h-pyrrolo (1,2-c) thiazolecarboxylique-7 dextrogyre |
| FR2626004B1 (fr) * | 1988-01-20 | 1991-08-02 | Rhone Poulenc Sante | Procede de preparation du (pyridyl-3)-3 1h, 3h-pyrrolo (1,2-c) thiazolecarbonitrile-7 |
| JP3061631B2 (ja) * | 1989-10-11 | 2000-07-10 | 山之内製薬株式会社 | 新規なヘテロ環化合物およびその製造法 |
-
1992
- 1992-07-14 DK DK92915895T patent/DK0595924T3/da active
- 1992-07-14 KR KR1019940700139A patent/KR100251603B1/ko not_active IP Right Cessation
- 1992-07-14 AU AU23391/92A patent/AU651243B2/en not_active Ceased
- 1992-07-14 AT AT92915895T patent/ATE178796T1/de not_active IP Right Cessation
- 1992-07-14 EP EP92915895A patent/EP0595924B1/en not_active Expired - Lifetime
- 1992-07-14 IL IL102494A patent/IL102494A0/xx unknown
- 1992-07-14 JP JP05502913A patent/JP3135917B2/ja not_active Expired - Fee Related
- 1992-07-14 US US08/162,034 patent/US5459152A/en not_active Expired - Fee Related
- 1992-07-14 DE DE69228932T patent/DE69228932T2/de not_active Expired - Fee Related
- 1992-07-14 WO PCT/US1992/005890 patent/WO1993001813A1/en active IP Right Grant
- 1992-07-14 CA CA002112562A patent/CA2112562A1/en not_active Abandoned
- 1992-07-14 IE IE229392A patent/IE922293A1/en unknown
- 1992-07-14 ES ES92915895T patent/ES2131530T3/es not_active Expired - Lifetime
- 1992-07-16 PT PT100698A patent/PT100698B/pt not_active IP Right Cessation
-
1999
- 1999-05-13 GR GR990401293T patent/GR3030208T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU651243B2 (en) | 1994-07-14 |
| PT100698A (pt) | 1993-10-29 |
| JPH06510027A (ja) | 1994-11-10 |
| ES2131530T3 (es) | 1999-08-01 |
| EP0595924A1 (en) | 1994-05-11 |
| CA2112562A1 (en) | 1993-02-04 |
| EP0595924A4 (en) | 1994-08-24 |
| IE922293A1 (en) | 1993-01-27 |
| AU2339192A (en) | 1993-02-23 |
| PT100698B (pt) | 1999-07-30 |
| US5459152A (en) | 1995-10-17 |
| JP3135917B2 (ja) | 2001-02-19 |
| EP0595924B1 (en) | 1999-04-14 |
| KR100251603B1 (ko) | 2000-05-01 |
| GR3030208T3 (en) | 1999-08-31 |
| DE69228932D1 (de) | 1999-05-20 |
| WO1993001813A1 (en) | 1993-02-04 |
| ATE178796T1 (de) | 1999-04-15 |
| DE69228932T2 (de) | 1999-11-11 |
| DK0595924T3 (da) | 1999-11-01 |
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