IL100746A0 - Nitrogen heterocycles - Google Patents
Nitrogen heterocyclesInfo
- Publication number
- IL100746A0 IL100746A0 IL100746A IL10074692A IL100746A0 IL 100746 A0 IL100746 A0 IL 100746A0 IL 100746 A IL100746 A IL 100746A IL 10074692 A IL10074692 A IL 10074692A IL 100746 A0 IL100746 A0 IL 100746A0
- Authority
- IL
- Israel
- Prior art keywords
- nitrogen heterocycles
- heterocycles
- nitrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919102807A GB9102807D0 (en) | 1991-02-11 | 1991-02-11 | Nitrogen heterocycles |
| GB919110593A GB9110593D0 (en) | 1991-05-16 | 1991-05-16 | Heterocyclic derivatives |
| GB919113183A GB9113183D0 (en) | 1991-06-18 | 1991-06-18 | Nitrogen compounds |
| GB919116314A GB9116314D0 (en) | 1991-07-29 | 1991-07-29 | Heterocyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL100746A0 true IL100746A0 (en) | 1992-09-06 |
Family
ID=27450623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL100746A IL100746A0 (en) | 1991-02-11 | 1992-01-23 | Nitrogen heterocycles |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5236937A (cs) |
| EP (1) | EP0499415A1 (cs) |
| JP (1) | JPH0592956A (cs) |
| KR (1) | KR920016447A (cs) |
| AU (1) | AU1040992A (cs) |
| CA (1) | CA2060107A1 (cs) |
| CS (1) | CS36192A3 (cs) |
| FI (1) | FI920564L (cs) |
| GB (1) | GB9202585D0 (cs) |
| HU (1) | HUT60488A (cs) |
| IE (1) | IE920175A1 (cs) |
| IL (1) | IL100746A0 (cs) |
| MX (1) | MX9200559A (cs) |
| NO (1) | NO920377L (cs) |
| ZW (1) | ZW1492A1 (cs) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5284954A (en) * | 1990-09-10 | 1994-02-08 | Abbott Laboratories | Process for the preparation of tetrazoles |
| GB9121727D0 (en) * | 1991-10-14 | 1991-11-27 | Ici Plc | Heterocyclic compounds |
| US5364869A (en) * | 1992-03-09 | 1994-11-15 | Abbott Laboratories | Heterocycle-substituted benzyaminopyridine angiotensin II receptor antagonists |
| TW348175B (en) * | 1993-01-06 | 1998-12-21 | Hoechst Ag | Process for the preparation of biphenyl derivatives |
| FR2711367B1 (fr) * | 1993-10-19 | 1995-12-01 | Roussel Uclaf | Nouveau procédé de préparation de dérivés soufrés de l'imidazole et les nouveaux intermédiaires obtenus. |
| DE4320432A1 (de) * | 1993-06-21 | 1994-12-22 | Bayer Ag | Substituierte Mono- und Bipyridylmethylderivate |
| US6455734B1 (en) | 2000-08-09 | 2002-09-24 | Magnesium Diagnostics, Inc. | Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states |
| SE9903028D0 (sv) | 1999-08-27 | 1999-08-27 | Astra Ab | New use |
| US6521618B2 (en) | 2000-03-28 | 2003-02-18 | Wyeth | 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors |
| US7507753B2 (en) * | 2001-12-28 | 2009-03-24 | Takeda Chemical Industries Ltd. | Biaryl compound and use thereof |
| EP2399903A1 (en) | 2002-05-24 | 2011-12-28 | Millennium Pharmaceuticals, Inc. | Ccr9 inhibitors and methods of use thereof |
| GB0225548D0 (en) | 2002-11-01 | 2002-12-11 | Glaxo Group Ltd | Compounds |
| WO2006078941A2 (en) * | 2005-01-20 | 2006-07-27 | Sirtris Pharmaceuticals, Inc. | Novel sirtuin activating compounds and methods of use thereof |
| CA2604797C (en) | 2005-04-12 | 2013-05-28 | Vicore Pharma Ab | New tricyclic angiotensin ii agonists |
| MX2007012633A (es) * | 2005-04-12 | 2008-01-11 | Vicore Pharma Ab | Nuevos agonistas biciclicos de angiotensina ii. |
| KR101284573B1 (ko) | 2005-04-12 | 2013-07-11 | 바이코어 파마 아베 | 신규한 트리시클릭 안지오텐신 ⅱ 아고니스트 |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| MX2009013293A (es) | 2007-06-04 | 2010-02-15 | Synergy Pharmaceuticals Inc | Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos. |
| EP2810951B1 (en) | 2008-06-04 | 2017-03-15 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| CA2730603C (en) | 2008-07-16 | 2019-09-24 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| JP2016514670A (ja) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト |
| JP2016514671A (ja) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼのアゴニストおよびその使用 |
| EA201592263A1 (ru) | 2013-06-05 | 2016-05-31 | Синерджи Фармасьютикалз, Инк. | Ультрачистые агонисты гуанилатциклазы c, способ их получения и использования |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0009465A1 (de) * | 1978-09-20 | 1980-04-02 | Ciba-Geigy Ag | N-(1-(4-Amino-2-chinazolinyl)-3- oder -4-piperidyl-lactame, Verfahren zu ihrer Herstellung, sowie pharmazeutische Präparate enthaltend diese Verbindungen |
| CA1334092C (en) * | 1986-07-11 | 1995-01-24 | David John Carini | Angiotensin ii receptor blocking imidazoles |
| US4820843A (en) * | 1987-05-22 | 1989-04-11 | E. I. Du Pont De Nemours And Company | Tetrazole intermediates to antihypertensive compounds |
| US5015651A (en) * | 1988-01-07 | 1991-05-14 | E. I. Du Pont De Nemours And Company | Treatment of hypertension with 1,2,4-angiotensin II antagonists |
| US4880804A (en) * | 1988-01-07 | 1989-11-14 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking benzimidazoles |
| GB8804439D0 (en) * | 1988-02-25 | 1988-03-23 | Pfizer Ltd | Dihydropyridines |
| DE69016125T2 (de) * | 1989-08-11 | 1995-06-01 | Zeneca Ltd | Chinolin-Derivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel. |
| CA2037630C (en) * | 1990-03-07 | 2001-07-03 | Akira Morimoto | Nitrogen-containing heterocylic compounds, their production and use |
| EP0453210A3 (en) * | 1990-04-19 | 1993-01-13 | Imperial Chemical Industries Plc | Pyridine derivatives |
| AU653734B2 (en) * | 1990-06-19 | 1994-10-13 | Meiji Seika Kabushiki Kaisha | Substituted 4-biphenylmethoxypyridine derivatives |
| IE912956A1 (en) * | 1990-09-10 | 1992-03-11 | Abbott Lab | Angiotensin ii receptor antagonists |
-
1992
- 1992-01-21 IE IE017592A patent/IE920175A1/en unknown
- 1992-01-22 AU AU10409/92A patent/AU1040992A/en not_active Abandoned
- 1992-01-23 IL IL100746A patent/IL100746A0/xx unknown
- 1992-01-27 ZW ZW14/92A patent/ZW1492A1/xx unknown
- 1992-01-28 CA CA002060107A patent/CA2060107A1/en not_active Abandoned
- 1992-01-28 NO NO92920377A patent/NO920377L/no unknown
- 1992-01-29 HU HU9200268A patent/HUT60488A/hu unknown
- 1992-02-07 CS CS92361A patent/CS36192A3/cs unknown
- 1992-02-07 GB GB929202585A patent/GB9202585D0/en active Pending
- 1992-02-07 EP EP92301048A patent/EP0499415A1/en not_active Withdrawn
- 1992-02-10 KR KR1019920002019A patent/KR920016447A/ko not_active Withdrawn
- 1992-02-10 MX MX9200559A patent/MX9200559A/es unknown
- 1992-02-11 FI FI920564A patent/FI920564L/fi unknown
- 1992-02-11 US US07/834,038 patent/US5236937A/en not_active Expired - Fee Related
- 1992-02-12 JP JP4073623A patent/JPH0592956A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US5236937A (en) | 1993-08-17 |
| JPH0592956A (ja) | 1993-04-16 |
| ZW1492A1 (en) | 1992-09-30 |
| FI920564A0 (fi) | 1992-02-11 |
| MX9200559A (es) | 1992-08-01 |
| CA2060107A1 (en) | 1992-08-12 |
| FI920564A7 (fi) | 1992-08-12 |
| GB9202585D0 (en) | 1992-03-25 |
| NO920377L (no) | 1992-08-12 |
| HUT60488A (en) | 1992-09-28 |
| HU9200268D0 (en) | 1992-04-28 |
| FI920564L (fi) | 1992-08-12 |
| CS36192A3 (en) | 1992-08-12 |
| EP0499415A1 (en) | 1992-08-19 |
| NO920377D0 (no) | 1992-01-28 |
| KR920016447A (ko) | 1992-09-24 |
| AU1040992A (en) | 1992-08-13 |
| IE920175A1 (en) | 1992-08-12 |
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