IL100195A0 - Use of xanthines for the preparation of a medicament having immuno suppressing activity - Google Patents

Use of xanthines for the preparation of a medicament having immuno suppressing activity

Info

Publication number
IL100195A0
IL100195A0 IL100195A IL10019591A IL100195A0 IL 100195 A0 IL100195 A0 IL 100195A0 IL 100195 A IL100195 A IL 100195A IL 10019591 A IL10019591 A IL 10019591A IL 100195 A0 IL100195 A0 IL 100195A0
Authority
IL
Israel
Prior art keywords
xanthines
medicament
preparation
suppressing activity
immuno
Prior art date
Application number
IL100195A
Other languages
English (en)
Original Assignee
Hoechst Roussel Pharma
Hutchinson Fred Cancer Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma, Hutchinson Fred Cancer Res filed Critical Hoechst Roussel Pharma
Publication of IL100195A0 publication Critical patent/IL100195A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL100195A 1990-11-30 1991-11-28 Use of xanthines for the preparation of a medicament having immuno suppressing activity IL100195A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62048090A 1990-11-30 1990-11-30

Publications (1)

Publication Number Publication Date
IL100195A0 true IL100195A0 (en) 1992-08-18

Family

ID=24486121

Family Applications (1)

Application Number Title Priority Date Filing Date
IL100195A IL100195A0 (en) 1990-11-30 1991-11-28 Use of xanthines for the preparation of a medicament having immuno suppressing activity

Country Status (10)

Country Link
EP (1) EP0490181A1 (enExample)
JP (1) JPH06100450A (enExample)
KR (1) KR920009399A (enExample)
CA (1) CA2056723A1 (enExample)
HU (1) HUT59825A (enExample)
IE (1) IE914163A1 (enExample)
IL (1) IL100195A0 (enExample)
PT (1) PT99659A (enExample)
TW (1) TW205507B (enExample)
ZA (1) ZA919438B (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU664189B2 (en) * 1991-05-24 1995-11-09 Fred Hutchinson Cancer Research Center Modulation of cellular response to external stimuli
DE4411660A1 (de) * 1994-04-05 1995-10-12 Hoechst Ag Verwendung von Xanthinderivaten zur Reduktion der pathologischen Hyperreagibilität eosinophiler Granulozyten, neue Xanthinverbindungen und Verfahren zu deren Herstellung
DE4430127A1 (de) * 1994-08-25 1996-03-14 Hoechst Ag Kombinationspräparat, enthaltend Cyclosporin A oder FK506 und ein Xanthinderivat
DE4430128A1 (de) * 1994-08-25 1996-02-29 Hoechst Ag Kombinationspräparat mit immunsuppressiven, kardiovaskulären und cerebralen Wirkungen
US6323201B1 (en) 1994-12-29 2001-11-27 The Regents Of The University Of California Compounds for inhibition of ceramide-mediated signal transduction
DE69812070T2 (de) * 1998-04-24 2003-12-11 K.U. Leuven Research & Development, Leuven Immununterdrückende Effekte von 8 substituierten Xanthinderivaten
US6930101B1 (en) 1999-05-17 2005-08-16 The Regents Of The University Of California Thiazolopyrimidines useful as TNFα inhibitors
US7253176B1 (en) 2000-05-04 2007-08-07 K.U. Leuven Research & Development Immunosuppressive effects of 8-substituted xanthine derivatives
KR20100121527A (ko) 2008-02-29 2010-11-17 콘서트 파마슈티컬즈, 인크. 치환된 잔틴 유도체
US20110053961A1 (en) 2009-02-27 2011-03-03 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
CA2771331A1 (en) 2009-09-02 2011-03-10 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
EP2611807A2 (en) 2010-09-01 2013-07-10 Concert Pharmaceuticals Inc. Polymorphs of (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3-7-dimethyl-1h-purine-2,6(3h,7h)dione
US20140296263A1 (en) 2011-07-19 2014-10-02 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
CN104364255A (zh) 2012-04-13 2015-02-18 康塞特医药品有限公司 取代的黄嘌呤衍生物
WO2013159006A1 (en) 2012-04-20 2013-10-24 Concert Pharmaceuticals, Inc. Polymorphs of (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3,7-dimethyl-1h-purine-2,6(3h,7h)-dione
US9549869B2 (en) 2012-06-29 2017-01-24 Hill-Rom Canado Respiratory Ltd. Wearable thorax percussion device

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0063827B1 (fr) * 1980-05-02 1985-08-14 Societe Des Produits Nestle S.A. 1-Isopropyl- et 1-isobutyl-3,7-diméthylxanthine comme médicaments
IL106861A (en) * 1986-12-31 1997-02-18 Hoechst Roussel Pharma Pentoxifylline metabolites and pharmaceutical formulations containing them for inhibiting the activity of interleukin-1 and leukocyte-derived cytokines
US4965271A (en) * 1986-12-31 1990-10-23 Hoechst Roussel Pharmaceuticals, Inc. Method of inhibiting the activity of leukocyte derived cytokines
GB8918297D0 (en) * 1989-08-10 1989-09-20 Beecham Group Plc Novel treatment

Also Published As

Publication number Publication date
KR920009399A (ko) 1992-06-25
JPH06100450A (ja) 1994-04-12
HUT59825A (en) 1992-07-28
IE914163A1 (en) 1992-06-03
TW205507B (enExample) 1993-05-11
EP0490181A1 (en) 1992-06-17
CA2056723A1 (en) 1992-05-31
ZA919438B (en) 1992-08-26
PT99659A (pt) 1992-10-30
HU913721D0 (en) 1992-02-28

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