IL100124A - Method and apparatus for optically screening microscopic cells - Google Patents

Method and apparatus for optically screening microscopic cells

Info

Publication number
IL100124A
IL100124A IL10012491A IL10012491A IL100124A IL 100124 A IL100124 A IL 100124A IL 10012491 A IL10012491 A IL 10012491A IL 10012491 A IL10012491 A IL 10012491A IL 100124 A IL100124 A IL 100124A
Authority
IL
Israel
Prior art keywords
cells
microspheres
bound
reactant
combining
Prior art date
Application number
IL10012491A
Other languages
English (en)
Other versions
IL100124A0 (en
Original Assignee
Coulter Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/617,096 external-priority patent/US5340719A/en
Application filed by Coulter Corp filed Critical Coulter Corp
Publication of IL100124A0 publication Critical patent/IL100124A0/xx
Publication of IL100124A publication Critical patent/IL100124A/en

Links

Classifications

    • G01N33/575—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
    • G01N15/147—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/06—Investigating concentration of particle suspensions
    • G01N15/0606—Investigating concentration of particle suspensions by collecting particles on a support
    • G01N15/0618—Investigating concentration of particle suspensions by collecting particles on a support of the filter type
    • G01N15/0625—Optical scan of the deposits
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
    • G01N2015/1472—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle with colour

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL10012491A 1990-11-23 1991-11-22 Method and apparatus for optically screening microscopic cells IL100124A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/617,096 US5340719A (en) 1990-11-23 1990-11-23 Method and apparatus for optically screening microscopic cells
US78215591A 1991-10-24 1991-10-24

Publications (2)

Publication Number Publication Date
IL100124A0 IL100124A0 (en) 1992-08-18
IL100124A true IL100124A (en) 1995-12-31

Family

ID=27087944

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10012491A IL100124A (en) 1990-11-23 1991-11-22 Method and apparatus for optically screening microscopic cells

Country Status (12)

Country Link
US (1) US5554505A (enExample)
EP (1) EP0558639A1 (enExample)
JP (1) JPH06503171A (enExample)
CN (1) CN1062212A (enExample)
AU (1) AU652599B2 (enExample)
CA (1) CA2096502A1 (enExample)
EG (1) EG19765A (enExample)
HU (1) HUT67053A (enExample)
IL (1) IL100124A (enExample)
MX (1) MX9102194A (enExample)
NO (1) NO931763L (enExample)
WO (1) WO1992009878A1 (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5348859A (en) * 1990-11-23 1994-09-20 Coulter Corporation Method and apparatus for obtaining an absolute white blood cell subset count and white blood cell multipart differential
US5374531A (en) * 1993-03-22 1994-12-20 Zynaxis, Inc. Immunoassay for determination of cells
US5989835A (en) 1997-02-27 1999-11-23 Cellomics, Inc. System for cell-based screening
US6316215B1 (en) 1999-12-27 2001-11-13 Edwin L. Adair Methods of cancer screening utilizing fluorescence detection techniques and selectable imager charge integration periods
US6251615B1 (en) 1998-02-20 2001-06-26 Cell Analytics, Inc. Cell analysis methods
EP1145149B1 (en) * 1998-11-13 2005-04-06 Cellomics, Inc. Methods and system for efficient collection and storage of experimental data
US6468764B1 (en) * 1999-01-20 2002-10-22 Walden Lewis Gibbs Automated staining and decolorization of biological material
US6828157B1 (en) * 1999-05-04 2004-12-07 Dan A. Pankowsky Products and methods for single parameter and multiparameter phenotyping of cells
US6682940B2 (en) 1999-05-04 2004-01-27 Dan A. Pankowsky Products and methods for single parameter and multiparameter phenotyping of cells
GB2355790A (en) * 1999-10-27 2001-05-02 Kay Cottington Detecting cancer
US6750037B2 (en) 1999-12-27 2004-06-15 Edwin L. Adair Method of cancer screening primarily utilizing non-invasive cell collection, fluorescence detection techniques, and radio tracing detection techniques
US6190877B1 (en) 1999-12-27 2001-02-20 Edwin L. Adair Method of cancer screening primarily utilizing non-invasive cell collection and fluorescence detection techniques
US6984498B2 (en) * 1999-12-27 2006-01-10 Adair Edwin L Method of cancer screening primarily utilizing non-invasive cell collection, fluorescence detection techniques, and radio tracing detection techniques
AU2001229744A1 (en) 2000-01-25 2001-08-07 Cellomics, Inc. Method and system for automated inference of physico-chemical interaction knowl edge
US6813615B1 (en) 2000-09-06 2004-11-02 Cellomics, Inc. Method and system for interpreting and validating experimental data with automated reasoning
US6768982B1 (en) 2000-09-06 2004-07-27 Cellomics, Inc. Method and system for creating and using knowledge patterns
WO2003038432A1 (en) * 2001-07-13 2003-05-08 Curagen Corporation Chi square tests for gene expression
EP1451304A4 (en) * 2001-11-07 2006-09-20 Bioview Ltd KITS AND METHODS FOR PREPARING CELLULAR SAMPLES OPTIMIZED FOR DUAL COLORING
US7141369B2 (en) * 2002-04-25 2006-11-28 Semibio Technology, Inc. Measuring cellular metabolism of immobilized cells
ATE336266T1 (de) * 2002-06-21 2006-09-15 Adair Edwin Lloyd Anwendung von metalloporphyrinen zur behandlung von arteriosklerose
DE10305768A1 (de) * 2003-02-11 2004-08-19 Justus-Liebig-Universität Giessen Verfahren zum Färben von lipophilen Zellbestandteilen einer biologischen Probe
EP1612537B1 (en) * 2004-06-30 2012-12-19 Sysmex Corporation Specimen preparation apparatus, specimen preparation/analysis system and specimen plate
WO2007047796A2 (en) * 2005-10-17 2007-04-26 Institute For Systems Biology Tissue-and serum-derived glycoproteins and methods of their use
CN100545630C (zh) * 2006-12-18 2009-09-30 中国矿业大学(北京) 一种改进的丛枝菌根孢子密度快速测定方法
US9091621B2 (en) 2013-04-05 2015-07-28 GGB Company Multiple slide processing apparatus
CN105717116A (zh) * 2016-02-23 2016-06-29 中国农业大学 动物源性肉骨粉的种属鉴别方法和系统
EP3717887A4 (en) * 2017-11-28 2020-10-21 Alentic Microscience Inc. CLASSIFICATION OF MICRO BEADS IN NEAR FIELD IMAGING
JP7269692B2 (ja) * 2018-09-26 2023-05-09 シスメックス株式会社 検体測定システム及び検体測定方法
CN110543003A (zh) * 2019-09-05 2019-12-06 苏州大学 微球透镜探针组件及微球透镜显微成像系统

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3670072A (en) * 1969-01-15 1972-06-13 Cambridge Chem Products Inc Hematological stain system
US4029470A (en) * 1975-10-29 1977-06-14 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Automated single-slide staining device
JPS531086A (en) * 1976-06-25 1978-01-07 Toshiba Corp Analyzer
US4115535A (en) * 1977-06-22 1978-09-19 General Electric Company Diagnostic method employing a mixture of normally separable protein-coated particles
DE3000483A1 (de) * 1979-01-09 1980-07-17 Fuji Photo Film Co Ltd Mikrokapseln fuer immunologische bestimmungen
US4615878A (en) * 1980-03-12 1986-10-07 Lawrence Kass Metachromatic dye sorption means for differential determination of sub-populations of lymphocytes
JPS5842971A (ja) * 1981-09-07 1983-03-12 Fuji Photo Film Co Ltd 抗体を感作させたマイクロカプセルを用いる細胞性免疫測定法
US4511662A (en) * 1982-06-18 1985-04-16 Bio-Rad Laboratories, Inc. Simultaneous assay for T and B lymphocyte populations and subpopulations
JPS60157050A (ja) * 1984-01-27 1985-08-17 Mitsubishi Rayon Co Ltd リンパ球ｔ細胞百分率測定方法
US4714606A (en) * 1984-05-15 1987-12-22 Cytocolor Incorporated Method of staining and identifying cells and compositions thereof
US5006459A (en) * 1986-03-31 1991-04-09 T Cell Sciences, Inc. Therapeutic and diagnostic methods using soluble T cell surface molecules
CA1326435C (en) * 1987-03-13 1994-01-25 Wallace H. Coulter Method and apparatus for rapid mixing of small volumes for enhancing biological reactions
JPH07104349B2 (ja) * 1987-04-11 1995-11-13 株式会社日立製作所 細胞測定法
CA1339840C (en) * 1988-12-16 1998-04-28 Kenneth Kortright Method and apparatus for screening cells or formed bodies with populations expressing selected characteristics
US5348859A (en) * 1990-11-23 1994-09-20 Coulter Corporation Method and apparatus for obtaining an absolute white blood cell subset count and white blood cell multipart differential
US5340719A (en) * 1990-11-23 1994-08-23 Corporation Coulter Method and apparatus for optically screening microscopic cells

Also Published As

Publication number Publication date
EG19765A (en) 1996-02-29
AU652599B2 (en) 1994-09-01
IL100124A0 (en) 1992-08-18
HU9301467D0 (en) 1993-10-28
JPH06503171A (ja) 1994-04-07
US5554505A (en) 1996-09-10
MX9102194A (es) 1994-06-30
WO1992009878A1 (en) 1992-06-11
EP0558639A1 (en) 1993-09-08
NO931763D0 (no) 1993-05-14
HUT67053A (en) 1995-01-30
CN1062212A (zh) 1992-06-24
CA2096502A1 (en) 1992-05-24
AU9091091A (en) 1992-06-25
NO931763L (no) 1993-06-15
EP0558639A4 (enExample) 1994-02-16

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Legal Events

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FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees