IE781682L - N-(4-pyrazolidinyl) benzamides. - Google Patents
N-(4-pyrazolidinyl) benzamides.Info
- Publication number
- IE781682L IE781682L IE781682A IE168278A IE781682L IE 781682 L IE781682 L IE 781682L IE 781682 A IE781682 A IE 781682A IE 168278 A IE168278 A IE 168278A IE 781682 L IE781682 L IE 781682L
- Authority
- IE
- Ireland
- Prior art keywords
- alkyl
- lower alkyl
- phenyllower
- benzamides
- pyrazolidinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/04—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Otolaryngology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
N-(4-Pyrazolidinyl) benzamides having the formula <IMAGE> wherein R represents lower alkyl, lower cycloalkyl or phenyllower-alkyl; R<1> represents lower alkyl, lower cycloalkyl, or phenyllower-alkyl; R<2> represents hydrogen, lower alkyl or phenyl; R<3> represents hydroxy, cyano, nitro, amino, fluoro, chloro, bromo, trifluoromethyl, lower alkyl, lower alkoxy, sulphamoyl or acetamido; and n is zero, 1, 2 or 3, pharmaceutically acceptable acid addition salts thereof, and compositions comprising such compounds or salts and a pharmaceutically acceptable carrier, are useful for treating warm blooded animals for emesis and for facilitating gastric emptying.
[GB2003153A]
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US82603177A | 1977-08-19 | 1977-08-19 | |
US90036978A | 1978-04-26 | 1978-04-26 | |
US93012578A | 1978-08-01 | 1978-08-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
IE781682L true IE781682L (en) | 1979-02-19 |
IE47430B1 IE47430B1 (en) | 1984-03-21 |
Family
ID=27420183
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE1682/78A IE47430B1 (en) | 1977-08-19 | 1978-08-18 | N-(4-pyrazolidinyl)benzamides,pharmaceutical compositions containing them,and intermediates for preparing them |
Country Status (21)
Country | Link |
---|---|
JP (1) | JPS5441873A (en) |
AU (1) | AU521421B2 (en) |
BR (1) | BR7805288A (en) |
CA (1) | CA1105037A (en) |
CH (2) | CH639374A5 (en) |
DE (1) | DE2836062A1 (en) |
DK (1) | DK152361C (en) |
ES (1) | ES472686A1 (en) |
FI (1) | FI68044C (en) |
FR (1) | FR2400511A1 (en) |
GB (2) | GB2003153B (en) |
HK (1) | HK42282A (en) |
IE (1) | IE47430B1 (en) |
MX (1) | MX5469E (en) |
NL (1) | NL7808596A (en) |
NO (1) | NO149107C (en) |
NZ (1) | NZ188189A (en) |
PH (1) | PH13331A (en) |
PT (1) | PT68442A (en) |
SE (2) | SE444434B (en) |
YU (1) | YU41116B (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4309552A (en) * | 1980-08-07 | 1982-01-05 | A. H. Robins Company, Inc. | Synthesis of 4-nitro-1,2-hydrocarbyl pyrazolidines and process for preparation thereof |
US5126343A (en) * | 1989-09-11 | 1992-06-30 | G. D. Searle & Co. | N-azabicyclo [3.3.0]octane amides of aromatic acids |
JP3065506B2 (en) | 1995-04-03 | 2000-07-17 | 株式会社資生堂 | Pyrazolidine derivative and radical scavenger, cerebral infarction inhibitor, cerebral edema inhibitor |
UY34104A (en) | 2011-05-31 | 2013-01-03 | Syngenta Participations Ag | ? HETEROCYCLIC BENZAMID DERIVATIVE COMPOUNDS, PROCESSES AND INTERMEDIATES FOR PREPARATION, COMPOSITIONS AND METHODS FOR USE. |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3966957A (en) * | 1972-04-03 | 1976-06-29 | A. H. Robins Company, Incorporated | Method for controlling emesis with N-(1-substituted-3-pyrrolidinyl)benzamides and thiobenzamides |
-
1976
- 1976-08-14 PH PH21489A patent/PH13331A/en unknown
-
1978
- 1978-08-15 CH CH867478A patent/CH639374A5/en not_active IP Right Cessation
- 1978-08-16 SE SE7808694A patent/SE444434B/en not_active IP Right Cessation
- 1978-08-16 FI FI782507A patent/FI68044C/en not_active IP Right Cessation
- 1978-08-17 GB GB7833696A patent/GB2003153B/en not_active Expired
- 1978-08-17 DE DE19782836062 patent/DE2836062A1/en not_active Withdrawn
- 1978-08-17 GB GB7901821A patent/GB2017678B/en not_active Expired
- 1978-08-17 BR BR7805288A patent/BR7805288A/en unknown
- 1978-08-18 YU YU1986/78A patent/YU41116B/en unknown
- 1978-08-18 NO NO782812A patent/NO149107C/en unknown
- 1978-08-18 IE IE1682/78A patent/IE47430B1/en unknown
- 1978-08-18 MX MX787322U patent/MX5469E/en unknown
- 1978-08-18 NZ NZ188189A patent/NZ188189A/en unknown
- 1978-08-18 DK DK366978A patent/DK152361C/en not_active IP Right Cessation
- 1978-08-18 FR FR7824138A patent/FR2400511A1/en active Granted
- 1978-08-18 ES ES472686A patent/ES472686A1/en not_active Expired
- 1978-08-18 CA CA309,651A patent/CA1105037A/en not_active Expired
- 1978-08-18 AU AU39061/78A patent/AU521421B2/en not_active Expired
- 1978-08-18 NL NL7808596A patent/NL7808596A/en not_active Application Discontinuation
- 1978-08-18 PT PT68442A patent/PT68442A/en unknown
- 1978-08-19 JP JP10136878A patent/JPS5441873A/en active Granted
-
1982
- 1982-09-30 HK HK422/82A patent/HK42282A/en unknown
-
1983
- 1983-04-28 CH CH228983A patent/CH645356A5/en not_active IP Right Cessation
- 1983-06-21 SE SE8303564A patent/SE451723B/en not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES8503476A1 (en) | Acrylic-acid amides, their preparation and use. | |
PH15864A (en) | 2-(2-alkoxy-methyl)-2-hydroxy-6-7 benzomorphans and salts thereof | |
DE3369315D1 (en) | Derivatives of 2-amino-3-acylamino-6-benzylamino pyridine with an anti-epileptic activity | |
ES2010284A6 (en) | Thiourea derivatives | |
IE45556L (en) | 2-[n-(cycloalkylmethyl)-n-(phenyl)-amino]-2- imidazoline¹derivatives | |
IE781682L (en) | N-(4-pyrazolidinyl) benzamides. | |
IE790297L (en) | Mercaptoacylamino acids | |
SE8200309L (en) | GUANIDINOCYKLOHEXANKARBOXYLSYRADERIVAT | |
ES8104293A1 (en) | 3-Substituted-tetrahydro-pyrrolo[1,2-a]pyrimidines and pharmaceutical compositions | |
ES8205219A1 (en) | Hydrouracil compounds. | |
DE3068456D1 (en) | 2-(n-(2-fluoro-6-bromophenyl)-n-(thiemyl-2-methyl)-amino)-2-imidazoline, its addition salts, pharmaceutical compositions containing them and processes for their preparation | |
ES8106147A1 (en) | 1,2,4-Triazole-3-thiols as antisecretory agents | |
ES8404150A1 (en) | N-pteridinyl ureas, process for their preparation and their use. | |
DE3369512D1 (en) | Triazole antifungal agents | |
JPS57200397A (en) | Novel aldohexopyranose-, aldopentopyranose-, or and medicament composition comprising it aldopentofuranose- nitrosourea compound, its preparation | |
JPS54128599A (en) | Pyrrolobenzazepin derivative | |
IL71987A (en) | N-(beta-fluoroethyl)nortropine,its preparation and use in preparation of the corresponding 3-alpha-benzilate | |
GB2005250A (en) | (1-Alkylpyrrolyl-2)thio- acetamides | |
AU579416B2 (en) | 3-Amino-2,3-dihydro-1-benzoxepine-compounds and methods for their preparation and pharmaceutical preparations containing these compounds | |
JPS5655373A (en) | Quinolinoneiminecarboxylic acid, its preparation, and antiphlogistic and analgesic composition containing said compound |