IE781682L - N-(4-pyrazolidinyl) benzamides. - Google Patents

N-(4-pyrazolidinyl) benzamides.

Info

Publication number
IE781682L
IE781682L IE781682A IE168278A IE781682L IE 781682 L IE781682 L IE 781682L IE 781682 A IE781682 A IE 781682A IE 168278 A IE168278 A IE 168278A IE 781682 L IE781682 L IE 781682L
Authority
IE
Ireland
Prior art keywords
alkyl
lower alkyl
phenyllower
benzamides
pyrazolidinyl
Prior art date
Application number
IE781682A
Other versions
IE47430B1 (en
Original Assignee
H H O Robins Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H H O Robins Co Inc filed Critical H H O Robins Co Inc
Publication of IE781682L publication Critical patent/IE781682L/en
Publication of IE47430B1 publication Critical patent/IE47430B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/04—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

N-(4-Pyrazolidinyl) benzamides having the formula <IMAGE> wherein R represents lower alkyl, lower cycloalkyl or phenyllower-alkyl; R<1> represents lower alkyl, lower cycloalkyl, or phenyllower-alkyl; R<2> represents hydrogen, lower alkyl or phenyl; R<3> represents hydroxy, cyano, nitro, amino, fluoro, chloro, bromo, trifluoromethyl, lower alkyl, lower alkoxy, sulphamoyl or acetamido; and n is zero, 1, 2 or 3, pharmaceutically acceptable acid addition salts thereof, and compositions comprising such compounds or salts and a pharmaceutically acceptable carrier, are useful for treating warm blooded animals for emesis and for facilitating gastric emptying. [GB2003153A]
IE1682/78A 1977-08-19 1978-08-18 N-(4-pyrazolidinyl)benzamides,pharmaceutical compositions containing them,and intermediates for preparing them IE47430B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US82603177A 1977-08-19 1977-08-19
US90036978A 1978-04-26 1978-04-26
US93012578A 1978-08-01 1978-08-01

Publications (2)

Publication Number Publication Date
IE781682L true IE781682L (en) 1979-02-19
IE47430B1 IE47430B1 (en) 1984-03-21

Family

ID=27420183

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1682/78A IE47430B1 (en) 1977-08-19 1978-08-18 N-(4-pyrazolidinyl)benzamides,pharmaceutical compositions containing them,and intermediates for preparing them

Country Status (21)

Country Link
JP (1) JPS5441873A (en)
AU (1) AU521421B2 (en)
BR (1) BR7805288A (en)
CA (1) CA1105037A (en)
CH (2) CH639374A5 (en)
DE (1) DE2836062A1 (en)
DK (1) DK152361C (en)
ES (1) ES472686A1 (en)
FI (1) FI68044C (en)
FR (1) FR2400511A1 (en)
GB (2) GB2003153B (en)
HK (1) HK42282A (en)
IE (1) IE47430B1 (en)
MX (1) MX5469E (en)
NL (1) NL7808596A (en)
NO (1) NO149107C (en)
NZ (1) NZ188189A (en)
PH (1) PH13331A (en)
PT (1) PT68442A (en)
SE (2) SE444434B (en)
YU (1) YU41116B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4309552A (en) * 1980-08-07 1982-01-05 A. H. Robins Company, Inc. Synthesis of 4-nitro-1,2-hydrocarbyl pyrazolidines and process for preparation thereof
US5126343A (en) * 1989-09-11 1992-06-30 G. D. Searle & Co. N-azabicyclo [3.3.0]octane amides of aromatic acids
JP3065506B2 (en) 1995-04-03 2000-07-17 株式会社資生堂 Pyrazolidine derivative and radical scavenger, cerebral infarction inhibitor, cerebral edema inhibitor
UY34104A (en) 2011-05-31 2013-01-03 Syngenta Participations Ag ? HETEROCYCLIC BENZAMID DERIVATIVE COMPOUNDS, PROCESSES AND INTERMEDIATES FOR PREPARATION, COMPOSITIONS AND METHODS FOR USE.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966957A (en) * 1972-04-03 1976-06-29 A. H. Robins Company, Incorporated Method for controlling emesis with N-(1-substituted-3-pyrrolidinyl)benzamides and thiobenzamides

Also Published As

Publication number Publication date
NL7808596A (en) 1979-02-21
JPS6315273B2 (en) 1988-04-04
CH639374A5 (en) 1983-11-15
DK152361B (en) 1988-02-22
YU198678A (en) 1983-01-21
GB2003153A (en) 1979-03-07
GB2017678B (en) 1982-03-10
PH13331A (en) 1980-03-13
DK366978A (en) 1979-02-20
AU521421B2 (en) 1982-04-01
NO149107B (en) 1983-11-07
SE8303564L (en) 1983-06-21
AU3906178A (en) 1980-02-21
FI782507A (en) 1979-02-20
FR2400511B1 (en) 1981-09-04
MX5469E (en) 1983-08-16
CH645356A5 (en) 1984-09-28
DE2836062A1 (en) 1979-03-01
GB2017678A (en) 1979-10-10
NO149107C (en) 1984-02-22
ES472686A1 (en) 1979-03-16
YU41116B (en) 1986-12-31
HK42282A (en) 1982-10-08
PT68442A (en) 1978-09-01
CA1105037A (en) 1981-07-14
NZ188189A (en) 1984-07-06
IE47430B1 (en) 1984-03-21
SE451723B (en) 1987-10-26
SE7808694L (en) 1979-02-20
FI68044B (en) 1985-03-29
FR2400511A1 (en) 1979-03-16
SE8303564D0 (en) 1983-06-21
JPS5441873A (en) 1979-04-03
BR7805288A (en) 1979-04-10
NO782812L (en) 1979-02-20
GB2003153B (en) 1982-02-24
DK152361C (en) 1988-07-25
SE444434B (en) 1986-04-14
FI68044C (en) 1985-07-10

Similar Documents

Publication Publication Date Title
ES8503476A1 (en) Acrylic-acid amides, their preparation and use.
PH15864A (en) 2-(2-alkoxy-methyl)-2-hydroxy-6-7 benzomorphans and salts thereof
DE3369315D1 (en) Derivatives of 2-amino-3-acylamino-6-benzylamino pyridine with an anti-epileptic activity
ES2010284A6 (en) Thiourea derivatives
IE45556L (en) 2-[n-(cycloalkylmethyl)-n-(phenyl)-amino]-2- imidazoline¹derivatives
IE781682L (en) N-(4-pyrazolidinyl) benzamides.
IE790297L (en) Mercaptoacylamino acids
SE8200309L (en) GUANIDINOCYKLOHEXANKARBOXYLSYRADERIVAT
ES8104293A1 (en) 3-Substituted-tetrahydro-pyrrolo[1,2-a]pyrimidines and pharmaceutical compositions
ES8205219A1 (en) Hydrouracil compounds.
DE3068456D1 (en) 2-(n-(2-fluoro-6-bromophenyl)-n-(thiemyl-2-methyl)-amino)-2-imidazoline, its addition salts, pharmaceutical compositions containing them and processes for their preparation
ES8106147A1 (en) 1,2,4-Triazole-3-thiols as antisecretory agents
ES8404150A1 (en) N-pteridinyl ureas, process for their preparation and their use.
DE3369512D1 (en) Triazole antifungal agents
JPS57200397A (en) Novel aldohexopyranose-, aldopentopyranose-, or and medicament composition comprising it aldopentofuranose- nitrosourea compound, its preparation
JPS54128599A (en) Pyrrolobenzazepin derivative
IL71987A (en) N-(beta-fluoroethyl)nortropine,its preparation and use in preparation of the corresponding 3-alpha-benzilate
GB2005250A (en) (1-Alkylpyrrolyl-2)thio- acetamides
AU579416B2 (en) 3-Amino-2,3-dihydro-1-benzoxepine-compounds and methods for their preparation and pharmaceutical preparations containing these compounds
JPS5655373A (en) Quinolinoneiminecarboxylic acid, its preparation, and antiphlogistic and analgesic composition containing said compound