ES2010284A6 - Thiourea derivatives - Google Patents
Thiourea derivativesInfo
- Publication number
- ES2010284A6 ES2010284A6 ES8802065A ES8802065A ES2010284A6 ES 2010284 A6 ES2010284 A6 ES 2010284A6 ES 8802065 A ES8802065 A ES 8802065A ES 8802065 A ES8802065 A ES 8802065A ES 2010284 A6 ES2010284 A6 ES 2010284A6
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- thiourea derivatives
- 4alkyl
- formylamino
- hydrolysable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/06—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms
- C07C335/10—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C335/12—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Abstract
Compounds of formula I < IMAGE > wherein R1 is halogen, C1-4alkyl, phenyl, benzyl, benzyloxy, nitro, cyano, trifluoromethyl, formylamino or C1-16 alkoxy R2 is hydrogen or has any one of the meanings given for R1 R3 is hydrogen or C1-4 alkyl and n is 1 or 2, physiologically-hydrolysable and -acceptable esters and salts thereof are indicated as analgesic and anti-inflammatory agents.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB878715357A GB8715357D0 (en) | 1987-06-30 | 1987-06-30 | Organic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2010284A6 true ES2010284A6 (en) | 1989-11-01 |
Family
ID=10619833
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8802065A Expired ES2010284A6 (en) | 1987-06-30 | 1988-06-30 | Thiourea derivatives |
Country Status (16)
Country | Link |
---|---|
JP (1) | JPS6426551A (en) |
KR (1) | KR890000417A (en) |
AU (1) | AU1846488A (en) |
DE (1) | DE3821317A1 (en) |
DK (1) | DK356588A (en) |
ES (1) | ES2010284A6 (en) |
FI (1) | FI883097A (en) |
FR (1) | FR2617477A1 (en) |
GB (2) | GB8715357D0 (en) |
IL (1) | IL86890A0 (en) |
IT (1) | IT1219676B (en) |
LU (1) | LU87261A1 (en) |
NL (1) | NL8801659A (en) |
PT (1) | PT87854B (en) |
SE (1) | SE8802412L (en) |
ZA (1) | ZA884693B (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5099030A (en) * | 1987-03-09 | 1992-03-24 | The Procter & Gamble Company | Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain |
US5045565A (en) * | 1987-03-09 | 1991-09-03 | The Procter & Gamble Company | Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain |
US5461075A (en) * | 1988-06-17 | 1995-10-24 | The Procter & Gamble Company | Use of vanilloids for the prevention of lesions due to herpes simplex infections |
GR880100400A (en) * | 1988-06-21 | 1990-05-11 | Sandoz Ag | Thiourea derivatives |
HU206082B (en) * | 1988-12-23 | 1992-08-28 | Sandoz Ag | Process for producing capsaicin derivatives and pharmaceutical compositions comprising such compounds |
US5403868A (en) * | 1988-12-23 | 1995-04-04 | Sandoz Ltd. | Capsaicin derivatives |
HU210683B (en) * | 1990-06-18 | 1995-06-28 | Sandoz Ag | Process for producing n-benzyl-n1-(phenyl-alkyl)-thiourea derivatives and pharmaceutical compositions containing the same |
TW476996B (en) | 2000-02-28 | 2002-02-21 | Mitsubishi Material Silicon | Semiconductor manufacturing method and semiconductor manufacturing apparatus |
US6313172B1 (en) * | 2000-04-13 | 2001-11-06 | Allergan Sales, Inc. | Methods and compositions for modulating alpha adrenergic receptor activity |
US6545182B2 (en) * | 2000-04-13 | 2003-04-08 | Allergan Sales, Inc. | Methods and compositions for modulating alpha adrenergic receptor activity |
EP1303483B1 (en) * | 2000-08-21 | 2008-04-23 | Pacific Corporation | Novel thiourea derivatives and the pharmaceutical compositions containing the same |
US7067553B2 (en) | 2000-08-21 | 2006-06-27 | Pacific Corporation | Thiourea compounds and the pharmaceutical compositions containing the same |
ITMI20041231A1 (en) * | 2004-06-18 | 2004-09-18 | Pharmeste Srl | VANILLOID RECEPTOR ANTAGONISTS TRPV1 |
EP1939173A1 (en) * | 2006-12-21 | 2008-07-02 | Pharmeste S.r.l. | O-substituted-dibenzyl urea- or thiourea- derivatives as trpv1 receptor antagonists |
-
1987
- 1987-06-30 GB GB878715357A patent/GB8715357D0/en active Pending
-
1988
- 1988-06-24 DE DE3821317A patent/DE3821317A1/en not_active Withdrawn
- 1988-06-27 GB GB08815258A patent/GB2206347A/en not_active Withdrawn
- 1988-06-27 FR FR8808719A patent/FR2617477A1/en not_active Withdrawn
- 1988-06-28 IT IT48132/88A patent/IT1219676B/en active
- 1988-06-28 LU LU87261A patent/LU87261A1/en unknown
- 1988-06-28 PT PT87854A patent/PT87854B/en not_active IP Right Cessation
- 1988-06-28 FI FI883097A patent/FI883097A/en not_active Application Discontinuation
- 1988-06-28 IL IL86890A patent/IL86890A0/en unknown
- 1988-06-28 AU AU18464/88A patent/AU1846488A/en not_active Abandoned
- 1988-06-28 SE SE8802412A patent/SE8802412L/en not_active Application Discontinuation
- 1988-06-28 DK DK356588A patent/DK356588A/en not_active Application Discontinuation
- 1988-06-29 JP JP63162367A patent/JPS6426551A/en active Pending
- 1988-06-29 KR KR1019880007885A patent/KR890000417A/en not_active Application Discontinuation
- 1988-06-30 ES ES8802065A patent/ES2010284A6/en not_active Expired
- 1988-06-30 NL NL8801659A patent/NL8801659A/en not_active Application Discontinuation
- 1988-06-30 ZA ZA884693A patent/ZA884693B/en unknown
Also Published As
Publication number | Publication date |
---|---|
GB8815258D0 (en) | 1988-08-03 |
SE8802412L (en) | 1988-12-31 |
FI883097A (en) | 1988-12-31 |
FR2617477A1 (en) | 1989-01-06 |
NL8801659A (en) | 1989-01-16 |
LU87261A1 (en) | 1989-03-08 |
IT8848132A0 (en) | 1988-06-28 |
JPS6426551A (en) | 1989-01-27 |
PT87854B (en) | 1992-10-30 |
SE8802412D0 (en) | 1988-06-28 |
FI883097A0 (en) | 1988-06-28 |
GB2206347A (en) | 1989-01-05 |
IL86890A0 (en) | 1988-11-30 |
DK356588D0 (en) | 1988-06-28 |
KR890000417A (en) | 1989-03-14 |
DK356588A (en) | 1988-12-31 |
ZA884693B (en) | 1990-03-28 |
PT87854A (en) | 1988-07-01 |
AU1846488A (en) | 1989-01-05 |
GB8715357D0 (en) | 1987-08-05 |
DE3821317A1 (en) | 1989-01-12 |
IT1219676B (en) | 1990-05-24 |
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