SE8802412D0 - THIOUREA DERIVATIVES - Google Patents

THIOUREA DERIVATIVES

Info

Publication number
SE8802412D0
SE8802412D0 SE8802412A SE8802412A SE8802412D0 SE 8802412 D0 SE8802412 D0 SE 8802412D0 SE 8802412 A SE8802412 A SE 8802412A SE 8802412 A SE8802412 A SE 8802412A SE 8802412 D0 SE8802412 D0 SE 8802412D0
Authority
SE
Sweden
Prior art keywords
hydrogen
thiourea derivatives
4alkyl
formylamino
hydrolysable
Prior art date
Application number
SE8802412A
Other languages
Swedish (sv)
Other versions
SE8802412L (en
Inventor
K J Masdin
C S J Walpole
R Wrigglesworth
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE8802412D0 publication Critical patent/SE8802412D0/en
Publication of SE8802412L publication Critical patent/SE8802412L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/06—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms
    • C07C335/10—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C335/12—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Compounds of formula I <IMAGE> wherein R1 is halogen, C1-4alkyl, phenyl, benzyl, benzyloxy, nitro, cyano, trifluoromethyl, formylamino or C1-16 alkoxy; R2 is hydrogen or has any one of the meanings given for R1; R3 is hydrogen or C1-4 alkyl; and n is 1 or 2, physiologically-hydrolysable and -acceptable esters and salts thereof are indicated as analgesic and anti-inflammatory agents.
SE8802412A 1987-06-30 1988-06-28 thiourea SE8802412L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878715357A GB8715357D0 (en) 1987-06-30 1987-06-30 Organic compounds

Publications (2)

Publication Number Publication Date
SE8802412D0 true SE8802412D0 (en) 1988-06-28
SE8802412L SE8802412L (en) 1988-12-31

Family

ID=10619833

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8802412A SE8802412L (en) 1987-06-30 1988-06-28 thiourea

Country Status (16)

Country Link
JP (1) JPS6426551A (en)
KR (1) KR890000417A (en)
AU (1) AU1846488A (en)
DE (1) DE3821317A1 (en)
DK (1) DK356588A (en)
ES (1) ES2010284A6 (en)
FI (1) FI883097A (en)
FR (1) FR2617477A1 (en)
GB (2) GB8715357D0 (en)
IL (1) IL86890A0 (en)
IT (1) IT1219676B (en)
LU (1) LU87261A1 (en)
NL (1) NL8801659A (en)
PT (1) PT87854B (en)
SE (1) SE8802412L (en)
ZA (1) ZA884693B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5099030A (en) * 1987-03-09 1992-03-24 The Procter & Gamble Company Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain
US5045565A (en) * 1987-03-09 1991-09-03 The Procter & Gamble Company Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain
US5461075A (en) * 1988-06-17 1995-10-24 The Procter & Gamble Company Use of vanilloids for the prevention of lesions due to herpes simplex infections
GR880100400A (en) * 1988-06-21 1990-05-11 Sandoz Ag Thiourea derivatives
HU206082B (en) * 1988-12-23 1992-08-28 Sandoz Ag Process for producing capsaicin derivatives and pharmaceutical compositions comprising such compounds
US5403868A (en) * 1988-12-23 1995-04-04 Sandoz Ltd. Capsaicin derivatives
HU210683B (en) * 1990-06-18 1995-06-28 Sandoz Ag Process for producing n-benzyl-n1-(phenyl-alkyl)-thiourea derivatives and pharmaceutical compositions containing the same
TW476996B (en) 2000-02-28 2002-02-21 Mitsubishi Material Silicon Semiconductor manufacturing method and semiconductor manufacturing apparatus
US6313172B1 (en) * 2000-04-13 2001-11-06 Allergan Sales, Inc. Methods and compositions for modulating alpha adrenergic receptor activity
US6545182B2 (en) * 2000-04-13 2003-04-08 Allergan Sales, Inc. Methods and compositions for modulating alpha adrenergic receptor activity
ATE328868T1 (en) 2000-08-21 2006-06-15 Pacific Corp NEW (THIO)UREA COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THEM
ATE393141T1 (en) * 2000-08-21 2008-05-15 Pacific Corp NEW THIOUREA DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
ITMI20041231A1 (en) * 2004-06-18 2004-09-18 Pharmeste Srl VANILLOID RECEPTOR ANTAGONISTS TRPV1
EP1939173A1 (en) * 2006-12-21 2008-07-02 Pharmeste S.r.l. O-substituted-dibenzyl urea- or thiourea- derivatives as trpv1 receptor antagonists

Also Published As

Publication number Publication date
AU1846488A (en) 1989-01-05
PT87854B (en) 1992-10-30
FI883097A0 (en) 1988-06-28
KR890000417A (en) 1989-03-14
FI883097A (en) 1988-12-31
DK356588D0 (en) 1988-06-28
FR2617477A1 (en) 1989-01-06
ZA884693B (en) 1990-03-28
GB2206347A (en) 1989-01-05
NL8801659A (en) 1989-01-16
GB8715357D0 (en) 1987-08-05
JPS6426551A (en) 1989-01-27
PT87854A (en) 1988-07-01
IL86890A0 (en) 1988-11-30
IT8848132A0 (en) 1988-06-28
GB8815258D0 (en) 1988-08-03
LU87261A1 (en) 1989-03-08
ES2010284A6 (en) 1989-11-01
DE3821317A1 (en) 1989-01-12
IT1219676B (en) 1990-05-24
SE8802412L (en) 1988-12-31
DK356588A (en) 1988-12-31

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Legal Events

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NAV Patent application has lapsed

Ref document number: 8802412-0

Effective date: 19900615