SE8802412L - thiourea - Google Patents

thiourea

Info

Publication number
SE8802412L
SE8802412L SE8802412A SE8802412A SE8802412L SE 8802412 L SE8802412 L SE 8802412L SE 8802412 A SE8802412 A SE 8802412A SE 8802412 A SE8802412 A SE 8802412A SE 8802412 L SE8802412 L SE 8802412L
Authority
SE
Sweden
Prior art keywords
hydrogen
thiourea
4alkyl
formylamino
hydrolysable
Prior art date
Application number
SE8802412A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE8802412D0 (en
Inventor
K J Masdin
C S J Walpole
R Wrigglesworth
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE8802412D0 publication Critical patent/SE8802412D0/en
Publication of SE8802412L publication Critical patent/SE8802412L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/06—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms
    • C07C335/10—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C335/12—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Compounds of formula I <IMAGE> wherein R1 is halogen, C1-4alkyl, phenyl, benzyl, benzyloxy, nitro, cyano, trifluoromethyl, formylamino or C1-16 alkoxy; R2 is hydrogen or has any one of the meanings given for R1; R3 is hydrogen or C1-4 alkyl; and n is 1 or 2, physiologically-hydrolysable and -acceptable esters and salts thereof are indicated as analgesic and anti-inflammatory agents.
SE8802412A 1987-06-30 1988-06-28 thiourea SE8802412L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878715357A GB8715357D0 (en) 1987-06-30 1987-06-30 Organic compounds

Publications (2)

Publication Number Publication Date
SE8802412D0 SE8802412D0 (en) 1988-06-28
SE8802412L true SE8802412L (en) 1988-12-31

Family

ID=10619833

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8802412A SE8802412L (en) 1987-06-30 1988-06-28 thiourea

Country Status (16)

Country Link
JP (1) JPS6426551A (en)
KR (1) KR890000417A (en)
AU (1) AU1846488A (en)
DE (1) DE3821317A1 (en)
DK (1) DK356588A (en)
ES (1) ES2010284A6 (en)
FI (1) FI883097A (en)
FR (1) FR2617477A1 (en)
GB (2) GB8715357D0 (en)
IL (1) IL86890A0 (en)
IT (1) IT1219676B (en)
LU (1) LU87261A1 (en)
NL (1) NL8801659A (en)
PT (1) PT87854B (en)
SE (1) SE8802412L (en)
ZA (1) ZA884693B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5045565A (en) * 1987-03-09 1991-09-03 The Procter & Gamble Company Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain
US5099030A (en) * 1987-03-09 1992-03-24 The Procter & Gamble Company Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain
US5461075A (en) * 1988-06-17 1995-10-24 The Procter & Gamble Company Use of vanilloids for the prevention of lesions due to herpes simplex infections
GR880100400A (en) * 1988-06-21 1990-05-11 Sandoz Ag Thiourea derivatives
US5403868A (en) * 1988-12-23 1995-04-04 Sandoz Ltd. Capsaicin derivatives
HU206082B (en) * 1988-12-23 1992-08-28 Sandoz Ag Process for producing capsaicin derivatives and pharmaceutical compositions comprising such compounds
HU210683B (en) * 1990-06-18 1995-06-28 Sandoz Ag Process for producing n-benzyl-n1-(phenyl-alkyl)-thiourea derivatives and pharmaceutical compositions containing the same
TW476996B (en) 2000-02-28 2002-02-21 Mitsubishi Material Silicon Semiconductor manufacturing method and semiconductor manufacturing apparatus
US6545182B2 (en) * 2000-04-13 2003-04-08 Allergan Sales, Inc. Methods and compositions for modulating alpha adrenergic receptor activity
US6313172B1 (en) * 2000-04-13 2001-11-06 Allergan Sales, Inc. Methods and compositions for modulating alpha adrenergic receptor activity
DE60120421T2 (en) * 2000-08-21 2006-12-28 Pacific Corp. NEW (THIO) UREA CONNECTIONS AND MEDICINAL COMPOSITIONS CONTAINING THEM
MXPA03001535A (en) * 2000-08-21 2004-12-13 Pacific Corp Novel thiourea derivatives and the pharmaceutical compositions containing the same.
ITMI20041231A1 (en) * 2004-06-18 2004-09-18 Pharmeste Srl VANILLOID RECEPTOR ANTAGONISTS TRPV1
EP1939173A1 (en) * 2006-12-21 2008-07-02 Pharmeste S.r.l. O-substituted-dibenzyl urea- or thiourea- derivatives as trpv1 receptor antagonists

Also Published As

Publication number Publication date
DE3821317A1 (en) 1989-01-12
IT1219676B (en) 1990-05-24
GB2206347A (en) 1989-01-05
SE8802412D0 (en) 1988-06-28
DK356588D0 (en) 1988-06-28
ES2010284A6 (en) 1989-11-01
PT87854B (en) 1992-10-30
AU1846488A (en) 1989-01-05
PT87854A (en) 1988-07-01
FR2617477A1 (en) 1989-01-06
FI883097A0 (en) 1988-06-28
DK356588A (en) 1988-12-31
IT8848132A0 (en) 1988-06-28
IL86890A0 (en) 1988-11-30
GB8715357D0 (en) 1987-08-05
ZA884693B (en) 1990-03-28
JPS6426551A (en) 1989-01-27
NL8801659A (en) 1989-01-16
GB8815258D0 (en) 1988-08-03
FI883097A (en) 1988-12-31
KR890000417A (en) 1989-03-14
LU87261A1 (en) 1989-03-08

Similar Documents

Publication Publication Date Title
FI904327A0 (en) N-SUBSTITUERAD-4-PYRIMIDINAMINER OCH -PYRIMIDINDIAMINER, FOERFARANDE FOER DERAS FRAMSTAELLNING OCH DERAS ANVAENDNING SOM LAEKEMEDEL.
FI963238A (en) Heteroaromatic oxazole compounds and their use
SE8601907L (en) ANTITROMBOGEN AND CARDIOTONIC IMIDAZOKINOLINES
SE8802412L (en) thiourea
FI861683A0 (en) N-INDOLYLETHYL-SULPHONYRIDE AMIDER, FOERFARANDE FOER DERAS FRAMSTAELLNING OCH DERAS ANVAENDNING.
FI861995A0 (en) FOERFARANDE FOER FRAMSTAELLNING AV THERAPEUTISKT ANVAENDBARA 2- (4-BENZOYL-1-PIPERIDINYL) -1-PHENYLALKANOLDERIVAT.
ATE25078T1 (en) 2-AMINO-3-ACYLAMINO-6-BENZYLAMINO-PYRIDINE DERIVATIVES WITH ANTI-EPILEPTIC ACTIVITY.
DE3772015D1 (en) CHINOLINE COMPOUND.
MX9102540A (en) DERIVATIVES OF BENZOXAZINONE AND BENZOTIAZINONE, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION THAT CONTAINS THEM.
SE8105689L (en) THERAPEUTIC AGENTS
DE68905406D1 (en) CHINOLINE COMPOUND.
SE8303564L (en) N- (4-pyrazolidinyl) benzamides
DE3068456D1 (en) 2-(n-(2-fluoro-6-bromophenyl)-n-(thiemyl-2-methyl)-amino)-2-imidazoline, its addition salts, pharmaceutical compositions containing them and processes for their preparation
FI854343A (en) PROCEDURE FOR FRAMSTATING AV 3-AMINO-2,3-DIHYDRO-1-BENZOXEPINFOERENINGAR.
DK382588D0 (en) ANTI-PSYCHOTIC COMPOSITIONS CONTAINING DIOXOPIPERIDINE DERIVATIVES
SE8105297L (en) imidazole
ATE36536T1 (en) PHOSPHOROIMIDATE.
DK501083D0 (en) SEMICARBAZIDES, PROCEDURE FOR THEIR MANUFACTURING AND THEIR USE

Legal Events

Date Code Title Description
NAV Patent application has lapsed

Ref document number: 8802412-0

Effective date: 19900615