IE49652B1 - Improved anti-inflammatory combinations having reduced ulcerogenicity - Google Patents

Improved anti-inflammatory combinations having reduced ulcerogenicity

Info

Publication number
IE49652B1
IE49652B1 IE633/80A IE63380A IE49652B1 IE 49652 B1 IE49652 B1 IE 49652B1 IE 633/80 A IE633/80 A IE 633/80A IE 63380 A IE63380 A IE 63380A IE 49652 B1 IE49652 B1 IE 49652B1
Authority
IE
Ireland
Prior art keywords
acid
methoxy
fever
inflammation
indomethacin
Prior art date
Application number
IE633/80A
Other languages
English (en)
Other versions
IE800633L (en
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IE800633L publication Critical patent/IE800633L/xx
Publication of IE49652B1 publication Critical patent/IE49652B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • A61K31/618Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate
    • A61K31/621Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate having the hydroxy group in position 2 esterified, e.g. benorylate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
IE633/80A 1979-03-28 1980-03-27 Improved anti-inflammatory combinations having reduced ulcerogenicity IE49652B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/024,639 US4228161A (en) 1979-03-28 1979-03-28 Anti-inflammatory combination having reduced ulcerogenicity

Publications (2)

Publication Number Publication Date
IE800633L IE800633L (en) 1980-09-28
IE49652B1 true IE49652B1 (en) 1985-11-13

Family

ID=21821627

Family Applications (1)

Application Number Title Priority Date Filing Date
IE633/80A IE49652B1 (en) 1979-03-28 1980-03-27 Improved anti-inflammatory combinations having reduced ulcerogenicity

Country Status (13)

Country Link
US (1) US4228161A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0017169B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS55130915A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR230953A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE2718T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU531174B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1124648A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3062251D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI800921A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE49652B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ193239A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT71015B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA801821B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU183408B (en) 1981-04-28 1984-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing oral ratard pharmaceutical compositions
WO1983001382A1 (en) * 1981-10-13 1983-04-28 Mroszczak, Edward Gastrointestinal sparing thioester pro-drugs
DE3366910D1 (en) * 1982-04-27 1986-11-20 Noristan Ltd Pharmaceutical compositions and preparation thereof
GB8607662D0 (en) * 1986-03-27 1986-04-30 Rainsford K D Pharmaceutical formulation
GB2201591B (en) * 1987-03-02 1990-11-14 Ricerfarma Srl Analgesic antipyretic and anti-inflammatory compositions.
US6767899B1 (en) * 2000-08-29 2004-07-27 Leiner Health Services Corp. Composition and method for treatment of conditions having an inflammatory component

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3161564A (en) * 1960-10-03 1964-12-15 Salsbury S Lab Dr Veterinary composition containing halo-nitro-benzamides and methods of using same
US3714226A (en) * 1970-06-09 1973-01-30 Merck & Co Inc Phenyl benzoic acid compounds
US3674870A (en) * 1970-06-09 1972-07-04 Merck & Co Inc Phenyl benzoic acid compounds in compositions and methods for treating inflammation
HU170329B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1974-12-12 1977-05-28
US4016268A (en) * 1975-10-06 1977-04-05 Morton-Norwich Products, Inc. Method of combatting gastric ulceration
GB1509979A (en) * 1975-11-28 1978-05-10 Fisons Ltd Pharmaceutical compositions containing aspirin or indomethacin

Also Published As

Publication number Publication date
US4228161A (en) 1980-10-14
JPS55130915A (en) 1980-10-11
NZ193239A (en) 1984-07-31
PT71015A (en) 1980-04-01
PT71015B (en) 1981-06-25
AU5653780A (en) 1980-10-02
DE3062251D1 (en) 1983-04-14
AU531174B2 (en) 1983-08-11
IE800633L (en) 1980-09-28
AR230953A1 (es) 1984-08-31
EP0017169A1 (en) 1980-10-15
FI800921A7 (fi) 1981-01-01
JPH0153247B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-11-13
CA1124648A (en) 1982-06-01
EP0017169B1 (en) 1983-03-09
ATE2718T1 (de) 1983-03-15
ZA801821B (en) 1981-11-25

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Legal Events

Date Code Title Description
MM4A Patent lapsed