IE46882B1 - Imidazo- (pyridine,pyrazine,pyrimidine and pyridazine) derivatives - Google Patents
Imidazo- (pyridine,pyrazine,pyrimidine and pyridazine) derivativesInfo
- Publication number
- IE46882B1 IE46882B1 IE923/78A IE92378A IE46882B1 IE 46882 B1 IE46882 B1 IE 46882B1 IE 923/78 A IE923/78 A IE 923/78A IE 92378 A IE92378 A IE 92378A IE 46882 B1 IE46882 B1 IE 46882B1
- Authority
- IE
- Ireland
- Prior art keywords
- compound
- hydrogen
- alkyl
- formula
- imidazo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/796,958 US4166851A (en) | 1977-05-16 | 1977-05-16 | Certain imidazo(1,2a)pyridine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE780923L IE780923L (en) | 1978-11-16 |
| IE46882B1 true IE46882B1 (en) | 1983-10-19 |
Family
ID=25169498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE923/78A IE46882B1 (en) | 1977-05-16 | 1978-05-08 | Imidazo- (pyridine,pyrazine,pyrimidine and pyridazine) derivatives |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4166851A (en, 2012) |
| JP (1) | JPS53141292A (en, 2012) |
| BE (1) | BE866841A (en, 2012) |
| CH (1) | CH639662A5 (en, 2012) |
| DE (1) | DE2820938A1 (en, 2012) |
| DK (1) | DK180878A (en, 2012) |
| FR (1) | FR2391215A1 (en, 2012) |
| GB (1) | GB1601041A (en, 2012) |
| IE (1) | IE46882B1 (en, 2012) |
| IT (1) | IT1156737B (en, 2012) |
| LU (1) | LU79651A1 (en, 2012) |
| NL (1) | NL7804345A (en, 2012) |
| SE (1) | SE7804777L (en, 2012) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4233301A (en) * | 1977-05-16 | 1980-11-11 | Merck & Co., Inc. | Novel imidazoazines and imidazodiazines |
| US4210653A (en) * | 1978-06-27 | 1980-07-01 | Merck & Co., Inc. | Pyridyloxypropanolamines |
| US4330543A (en) * | 1978-12-14 | 1982-05-18 | Merck & Co., Inc. | Imidazoazines and imidazodiazines |
| US4331679A (en) * | 1980-12-23 | 1982-05-25 | Merck Sharp & Dohme (I.A.) Corp. | (3-Aralkylamino-2-or-propoxy) heterocyclic compounds |
| US4442094A (en) * | 1980-12-23 | 1984-04-10 | Merck & Co., Inc. | (3-Aralkylamino-2-or-propoxy)heterocyclic compounds |
| US4349673A (en) * | 1980-12-23 | 1982-09-14 | Merck & Co., Inc. | Benzoxazines |
| US4656168A (en) * | 1980-12-23 | 1987-04-07 | Merck & Co., Inc. | (3-aralkylamino-2-or-propoxy)heterocyclic compounds in method of effecting bronchodilation |
| US4391806A (en) * | 1982-07-12 | 1983-07-05 | The Dow Chemical Company | Substituted tetrahydropyridazino-(1,6-A)benzimidazoles and use as bronchodilators |
| US4537889A (en) * | 1982-12-27 | 1985-08-27 | Eli Lilly And Company | Inotropic agents |
| US4636502A (en) * | 1982-12-27 | 1987-01-13 | Eli Lilly And Company | Methods of producing a positive inotropic effect or vasodilation by administration of 2-phenyl imidazo pyrimidines and pyrazines |
| RO87859B (ro) * | 1982-12-27 | 1985-12-31 | Eli Lilly And Company | Procedeu pentru prepararea unor derivati de inidazopirimidina pirezina si triazina |
| DE3446778A1 (de) * | 1984-12-21 | 1986-07-03 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
| GB8719368D0 (en) * | 1987-08-15 | 1987-09-23 | Wellcome Found | Heterocyclic compounds |
| PH27291A (en) * | 1989-01-31 | 1993-05-04 | Takeda Chemical Industries Ltd | Imidazolpyrimidazines their production and use |
| EP0440119A1 (en) * | 1990-01-31 | 1991-08-07 | Takeda Chemical Industries, Ltd. | Imidazopyridazine compounds, their production and use |
| US5244908A (en) * | 1990-07-30 | 1993-09-14 | Takeda Chemical Industries, Ltd. | Imidazopyridine derivatives and their pharmaceutical use |
| US5420133A (en) * | 1993-03-19 | 1995-05-30 | Merck & Co., Inc. | Quinazolinones substituted with phenoxyphenylacetic acid derivatives |
| DE10145457A1 (de) * | 2001-09-14 | 2003-04-03 | Basf Ag | Substituierte Imidazo[1,2-a]-5,6,7,8-tetrahydropyridin-8-one, Verfahren zu ihrer Herstellung, sowie deren Verwendung zur Herstellung von Imidazo[1,2,-a]pyridinen |
| US20070078136A1 (en) | 2005-09-22 | 2007-04-05 | Bristol-Myers Squibb Company | Fused heterocyclic compounds useful as kinase modulators |
| WO2010017047A1 (en) * | 2008-08-05 | 2010-02-11 | Merck & Co., Inc. | Therapeutic compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR208397A1 (es) * | 1973-02-20 | 1976-12-27 | Ciba Geigy Ag | Procedimiento para la elaboracion de compuestos de 1-piridiloxi-2-hidroxi-3-amino-propano1-piraziniloxi-2-hidroxi-3-amino-propano y 1-pirimidiniloxi-2-hidroxi-3-amino-propan |
| CH614711A5 (en, 2012) * | 1975-04-08 | 1979-12-14 | Sandoz Ag | |
| US4071630A (en) * | 1975-04-08 | 1978-01-31 | Sandoz Ltd. | 1-Substituted-amino-3-(4-furo[3,2-c]pyridinyloxy)-2-propanols |
-
1977
- 1977-05-16 US US05/796,958 patent/US4166851A/en not_active Expired - Lifetime
-
1978
- 1978-04-24 NL NL7804345A patent/NL7804345A/xx not_active Application Discontinuation
- 1978-04-26 DK DK180878A patent/DK180878A/da not_active Application Discontinuation
- 1978-04-26 SE SE7804777A patent/SE7804777L/xx unknown
- 1978-05-08 IE IE923/78A patent/IE46882B1/en unknown
- 1978-05-09 BE BE187505A patent/BE866841A/xx not_active IP Right Cessation
- 1978-05-12 LU LU79651A patent/LU79651A1/xx unknown
- 1978-05-12 DE DE19782820938 patent/DE2820938A1/de not_active Ceased
- 1978-05-12 IT IT49338/78A patent/IT1156737B/it active
- 1978-05-12 CH CH522978A patent/CH639662A5/de not_active IP Right Cessation
- 1978-05-12 GB GB19246/78A patent/GB1601041A/en not_active Expired
- 1978-05-12 FR FR7814248A patent/FR2391215A1/fr active Granted
- 1978-05-16 JP JP5723378A patent/JPS53141292A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| US4166851A (en) | 1979-09-04 |
| IT1156737B (it) | 1987-02-04 |
| BE866841A (fr) | 1978-11-09 |
| SE7804777L (sv) | 1978-11-17 |
| GB1601041A (en) | 1981-10-21 |
| IE780923L (en) | 1978-11-16 |
| IT7849338A0 (it) | 1978-05-12 |
| JPS623153B2 (en, 2012) | 1987-01-23 |
| DE2820938A1 (de) | 1978-11-23 |
| CH639662A5 (de) | 1983-11-30 |
| NL7804345A (nl) | 1978-11-20 |
| FR2391215B1 (en, 2012) | 1981-12-11 |
| JPS53141292A (en) | 1978-12-08 |
| LU79651A1 (fr) | 1979-02-02 |
| FR2391215A1 (fr) | 1978-12-15 |
| DK180878A (da) | 1978-11-17 |
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