LU79651A1 - Procede de preparation d'imidazoazines et-diazines substituees et leur utilisation - Google Patents

Procede de preparation d'imidazoazines et-diazines substituees et leur utilisation

Info

Publication number
LU79651A1
LU79651A1 LU79651A LU79651A LU79651A1 LU 79651 A1 LU79651 A1 LU 79651A1 LU 79651 A LU79651 A LU 79651A LU 79651 A LU79651 A LU 79651A LU 79651 A1 LU79651 A1 LU 79651A1
Authority
LU
Luxembourg
Prior art keywords
imidazoazines
preparation
diazines
substituted
substituted diazines
Prior art date
Application number
LU79651A
Other languages
English (en)
Inventor
W Lumma
J Baldwin
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of LU79651A1 publication Critical patent/LU79651A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
LU79651A 1977-05-16 1978-05-12 Procede de preparation d'imidazoazines et-diazines substituees et leur utilisation LU79651A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/796,958 US4166851A (en) 1977-05-16 1977-05-16 Certain imidazo(1,2a)pyridine derivatives

Publications (1)

Publication Number Publication Date
LU79651A1 true LU79651A1 (fr) 1979-02-02

Family

ID=25169498

Family Applications (1)

Application Number Title Priority Date Filing Date
LU79651A LU79651A1 (fr) 1977-05-16 1978-05-12 Procede de preparation d'imidazoazines et-diazines substituees et leur utilisation

Country Status (13)

Country Link
US (1) US4166851A (fr)
JP (1) JPS53141292A (fr)
BE (1) BE866841A (fr)
CH (1) CH639662A5 (fr)
DE (1) DE2820938A1 (fr)
DK (1) DK180878A (fr)
FR (1) FR2391215A1 (fr)
GB (1) GB1601041A (fr)
IE (1) IE46882B1 (fr)
IT (1) IT1156737B (fr)
LU (1) LU79651A1 (fr)
NL (1) NL7804345A (fr)
SE (1) SE7804777L (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4233301A (en) * 1977-05-16 1980-11-11 Merck & Co., Inc. Novel imidazoazines and imidazodiazines
US4210653A (en) * 1978-06-27 1980-07-01 Merck & Co., Inc. Pyridyloxypropanolamines
US4330543A (en) * 1978-12-14 1982-05-18 Merck & Co., Inc. Imidazoazines and imidazodiazines
US4442094A (en) * 1980-12-23 1984-04-10 Merck & Co., Inc. (3-Aralkylamino-2-or-propoxy)heterocyclic compounds
US4349673A (en) * 1980-12-23 1982-09-14 Merck & Co., Inc. Benzoxazines
US4331679A (en) * 1980-12-23 1982-05-25 Merck Sharp & Dohme (I.A.) Corp. (3-Aralkylamino-2-or-propoxy) heterocyclic compounds
US4656168A (en) * 1980-12-23 1987-04-07 Merck & Co., Inc. (3-aralkylamino-2-or-propoxy)heterocyclic compounds in method of effecting bronchodilation
US4391806A (en) * 1982-07-12 1983-07-05 The Dow Chemical Company Substituted tetrahydropyridazino-(1,6-A)benzimidazoles and use as bronchodilators
US4537889A (en) * 1982-12-27 1985-08-27 Eli Lilly And Company Inotropic agents
US4636502A (en) * 1982-12-27 1987-01-13 Eli Lilly And Company Methods of producing a positive inotropic effect or vasodilation by administration of 2-phenyl imidazo pyrimidines and pyrazines
PT77844B (en) * 1982-12-27 1986-05-08 Lilly Co Eli Process for preparing substituted imidazopyrimidines -pyrazines and -triazines
DE3446778A1 (de) * 1984-12-21 1986-07-03 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
GB8719368D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Heterocyclic compounds
PH27291A (en) * 1989-01-31 1993-05-04 Takeda Chemical Industries Ltd Imidazolpyrimidazines their production and use
EP0440119A1 (fr) * 1990-01-31 1991-08-07 Takeda Chemical Industries, Ltd. Composés de imidazopyridazine, leur préparation et utilisation
EP0471236B1 (fr) * 1990-07-30 1995-03-15 Takeda Chemical Industries, Ltd. Dérivés de l'imidazopyridine et leur application
US5420133A (en) * 1993-03-19 1995-05-30 Merck & Co., Inc. Quinazolinones substituted with phenoxyphenylacetic acid derivatives
DE10145457A1 (de) * 2001-09-14 2003-04-03 Basf Ag Substituierte Imidazo[1,2-a]-5,6,7,8-tetrahydropyridin-8-one, Verfahren zu ihrer Herstellung, sowie deren Verwendung zur Herstellung von Imidazo[1,2,-a]pyridinen
US20070078136A1 (en) 2005-09-22 2007-04-05 Bristol-Myers Squibb Company Fused heterocyclic compounds useful as kinase modulators
US8455477B2 (en) * 2008-08-05 2013-06-04 Merck Sharp & Dohme Corp. Therapeutic compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR207133A1 (es) * 1973-02-20 1976-09-15 Ciba Geigy Ag Procedimiento para la elaboracion de derivados de 1-piridiloxi 1-pirimidiniloxi y 1-piraziniloxi-2-hidroxi-3-amino-propano
US4071630A (en) * 1975-04-08 1978-01-31 Sandoz Ltd. 1-Substituted-amino-3-(4-furo[3,2-c]pyridinyloxy)-2-propanols
CH614711A5 (fr) * 1975-04-08 1979-12-14 Sandoz Ag

Also Published As

Publication number Publication date
CH639662A5 (de) 1983-11-30
JPS53141292A (en) 1978-12-08
IT1156737B (it) 1987-02-04
DE2820938A1 (de) 1978-11-23
NL7804345A (nl) 1978-11-20
JPS623153B2 (fr) 1987-01-23
GB1601041A (en) 1981-10-21
FR2391215B1 (fr) 1981-12-11
IE780923L (en) 1978-11-16
IT7849338A0 (it) 1978-05-12
SE7804777L (sv) 1978-11-17
BE866841A (fr) 1978-11-09
FR2391215A1 (fr) 1978-12-15
US4166851A (en) 1979-09-04
DK180878A (da) 1978-11-17
IE46882B1 (en) 1983-10-19

Similar Documents

Publication Publication Date Title
BE865635A (fr) Procede d'osteosynthese
LU79651A1 (fr) Procede de preparation d'imidazoazines et-diazines substituees et leur utilisation
BE891094Q (fr) N-benzoyl-n'-pyridyloxy-phenylurees et leur procede de preparation
FR2449699B1 (fr) Polyetherpolyamides et leur procede de preparation
BE868417A (fr) Derives d'acide 1,2,3-thiadiazole-5-carboxylique leur procede de preparation et leur utilisation
BE869294A (fr) Procede de determination de l'amylase
LU79597A1 (fr) Procede de preparation de n-alkyl-n-acyl-thienamycines et leur utilisation
BE863872A (fr) Steroides-11 beta-substitues et procede de leur preparation
BE866957A (fr) Procede de preparation d'homopolymerisats et de copolymerisats d'alpha-mono-olefines
BE861172A (fr) Procede de preparation d'alpha-amino-amides
SE7809040L (sv) Apparat for indrivning av festorgan
BE865805A (fr) 1,2,3-thiadiazol-3-in-5-ylidene-urees, leur procede de preparation et leur utilisation
FR2305416A1 (fr) Procede de preparation de tricosene-(9) et d'heneicosene-(9)
BE872294A (fr) Procede de preparation de 3-iodorifamycine s et de 3-bromorifamycine s
BE878127A (fr) Amides 1,2,3-triazolecarboxyliques, leur procede de preparation et leur utilisation
BE884652R (fr) Phenoxyalcoyl trialcoxysilanes et leur procede de preparation
BE858806A (fr) Procede pour la preparation de glycol-aldehyde et d'ethylene-glycol
BE864483A (fr) Procede de preparation d'oxyde de propylene
FR2396584B1 (fr) Procede d'homogeneisation
RO78342A (fr) Procede de preparation des imino-ethers de benzthiazolines et benzoxazolines
BE854237A (fr) 1,2,3-thiadiazol-5-yl-urees, leur procede de preparation et leur utilisation
BE867086A (fr) Composes d'azacyclyle et procede pour leur preparation
FR2424281B1 (fr) Phenoxyalcoyl trialcoxysilanes et leur procede de preparation
BE869407A (fr) 2-cyclopropyl-chromones substituees et procede pour leur preparation
BE867228A (fr) Procede pour la preparation d'hydroxyphenylglycocolles