IE44684L - Methyl-3-(2-qionoxalinylmethylene) carbazate-n1, n4-dioxides - Google Patents

Methyl-3-(2-qionoxalinylmethylene) carbazate-n1, n4-dioxides

Info

Publication number
IE44684L
IE44684L IE771040A IE104077A IE44684L IE 44684 L IE44684 L IE 44684L IE 771040 A IE771040 A IE 771040A IE 104077 A IE104077 A IE 104077A IE 44684 L IE44684 L IE 44684L
Authority
IE
Ireland
Prior art keywords
formula
dioxides
carbazate
methyl
hydrazine
Prior art date
Application number
IE771040A
Other versions
IE44684B1 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to IE1630/81A priority Critical patent/IE44686B1/en
Priority to IE1629/81A priority patent/IE44685B1/en
Publication of IE44684L publication Critical patent/IE44684L/en
Publication of IE44684B1 publication Critical patent/IE44684B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/50Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
    • C07D241/52Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

The carbazates of formula I are obtained by reacting the quinoxaline N<1>,N<4>-dioxides carrying in position 2 a chloromethyl or bromomethyl group with one to two equivalents of an alkali metal carbonate and one to two equivalents of a hydrazine of formula R''NH-NH-COOCH3 at a temperature of between 75 and 85 DEG C and in an inert solvent. This hydrazine is prepared by reaction of methyl carbazate with a corresponding acid anhydride or sulphonyl halide which introduces the radical R''. The meaning of the symbols is explained in Claim 1. The compounds of formula I are strong antibacterial agents. <IMAGE> [GB1591872A]
IE1040/77A 1976-06-15 1977-05-20 Process for producing methyl 3-2(2-quinoxylinylmethylene) carbazate-n1,n4-dioxides IE44684B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IE1630/81A IE44686B1 (en) 1976-06-15 1977-05-20 N-methoxycarbonyl-n1-sulfonylhydrazines
IE1629/81A IE44685B1 (en) 1976-06-15 1977-05-20 Methyl 3-(2-quinoxalinylmethylene)carbazate-n1,n4-dioxides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69626376A 1976-06-15 1976-06-15

Publications (2)

Publication Number Publication Date
IE44684L true IE44684L (en) 1977-12-15
IE44684B1 IE44684B1 (en) 1982-02-24

Family

ID=24796354

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1040/77A IE44684B1 (en) 1976-06-15 1977-05-20 Process for producing methyl 3-2(2-quinoxylinylmethylene) carbazate-n1,n4-dioxides

Country Status (31)

Country Link
JP (2) JPS52153986A (en)
AR (1) AR221207A1 (en)
AT (1) AT357562B (en)
BG (1) BG35595A3 (en)
CA (1) CA1087616A (en)
CH (1) CH620911A5 (en)
CS (1) CS200218B2 (en)
DD (2) DD135080A5 (en)
DE (1) DE2725023A1 (en)
DK (1) DK142497B (en)
ES (2) ES459750A1 (en)
FI (1) FI771742A (en)
GB (3) GB1591874A (en)
GR (1) GR72289B (en)
HK (3) HK1883A (en)
IE (1) IE44684B1 (en)
IL (1) IL52166A0 (en)
IT (1) IT1078874B (en)
LU (1) LU77474A1 (en)
MY (2) MY8300230A (en)
NL (2) NL166685C (en)
NO (2) NO146864C (en)
NZ (1) NZ184167A (en)
PH (2) PH14866A (en)
PL (1) PL105555B1 (en)
PT (1) PT66618B (en)
SE (2) SE428925B (en)
SG (1) SG49282G (en)
SU (1) SU657746A3 (en)
YU (1) YU39492B (en)
ZA (1) ZA772979B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60164410A (en) * 1984-02-08 1985-08-27 株式会社石井製作所 Threshing and sorting apparatus

Also Published As

Publication number Publication date
NO771903L (en) 1977-12-16
HK2083A (en) 1983-01-13
BG35595A3 (en) 1984-05-15
NO147422C (en) 1983-04-06
ATA387077A (en) 1979-12-15
NO146864B (en) 1982-09-13
MY8300229A (en) 1983-12-31
FI771742A (en) 1977-12-16
DK240777A (en) 1977-12-16
SU657746A3 (en) 1979-04-15
ES459750A1 (en) 1978-04-01
NZ184167A (en) 1981-02-11
IT1078874B (en) 1985-05-08
ZA772979B (en) 1978-04-26
DK142497B (en) 1980-11-10
DE2725023A1 (en) 1977-12-22
SE428925B (en) 1983-08-01
GB1591873A (en) 1981-07-01
CH620911A5 (en) 1980-12-31
GB1591874A (en) 1981-07-01
NL166685C (en) 1981-09-15
SE7705744L (en) 1977-12-16
PT66618B (en) 1978-10-27
CA1087616A (en) 1980-10-14
PT66618A (en) 1977-06-01
PH14866A (en) 1982-01-08
HK1983A (en) 1983-01-13
PL105555B1 (en) 1979-10-31
NO813221L (en) 1977-12-16
MY8300230A (en) 1983-12-31
GB1591872A (en) 1981-07-01
NO147422B (en) 1982-12-27
NL8006697A (en) 1981-03-31
DK142497C (en) 1981-03-23
YU39492B (en) 1984-12-31
JPS5725542B2 (en) 1982-05-29
ES459745A1 (en) 1978-04-01
IE44684B1 (en) 1982-02-24
DD135080A5 (en) 1979-04-11
NO146864C (en) 1982-12-22
AT357562B (en) 1980-07-25
AR221207A1 (en) 1981-01-15
PH14481A (en) 1981-08-07
JPS52153986A (en) 1977-12-21
IL52166A0 (en) 1977-07-31
LU77474A1 (en) 1978-01-26
YU132777A (en) 1982-08-31
NL166685B (en) 1981-04-15
HK1883A (en) 1983-01-13
JPS5652019B2 (en) 1981-12-09
DD131371A5 (en) 1978-06-21
JPS5589256A (en) 1980-07-05
PL198873A1 (en) 1978-04-24
CS200218B2 (en) 1980-08-29
NL7705938A (en) 1977-12-19
SG49282G (en) 1984-02-17
GR72289B (en) 1983-10-17
SE437985B (en) 1985-03-25
SE8003393L (en) 1980-05-06

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Legal Events

Date Code Title Description
MM4A Patent lapsed