IE41131L - Isopropylamino - propan - 2 - ol derivatives - Google Patents
Isopropylamino - propan - 2 - ol derivativesInfo
- Publication number
- IE41131L IE41131L IE750168A IE16875A IE41131L IE 41131 L IE41131 L IE 41131L IE 750168 A IE750168 A IE 750168A IE 16875 A IE16875 A IE 16875A IE 41131 L IE41131 L IE 41131L
- Authority
- IE
- Ireland
- Prior art keywords
- formula
- compound
- image
- reacted
- starts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Novel amines of the formula (I) <IMAGE> in which R denotes methyl or ethyl, are prepared by an N-alkylation process. This starts either from a compound of the formula (II) <IMAGE> wherein X<1> denotes the hydroxyl group and Z a reactive esterified hydroxyl group or X<1> and Z together form an epoxy group, which compound is reacted with isopropylamine, or starts from a compound of the formula (III) <IMAGE> wherein R has the above meaning, which is reacted with a compound of the formula (IV> Z-CH=(CH3)2 (IV> wherein Z has the abovementioned meaning. The amines are obtained in the form of free bases or of therapeutically acceptable acid addition salts. The compounds of the formula (I) possess valuable pharmacological properties; they exhibit, for example, cardioselective ss-receptorblocking properties whilst retaining activities which are useful in the treatment of Angina pectoris.
[SE7401096A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE7401096A SE419754B (en) | 1974-01-29 | 1974-01-29 | ANALOGY PROCEDURE FOR PREPARING TWO NEW SUBSTITUTED PHENOXYPROPANOLAMINES WITH ALFA RECEPTOR BLOCKING EFFECT |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE41131L true IE41131L (en) | 1975-07-29 |
| IE41131B1 IE41131B1 (en) | 1979-10-24 |
Family
ID=20320031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE168/75A IE41131B1 (en) | 1974-01-29 | 1975-01-28 | 3-(4-(2-alkoxy carbonylamino ethyl)-phenoxy)-1-isopropylamino-propan-2-ols, methods for their preparation and compositions containing them |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS50106930A (en) |
| AT (1) | AT336037B (en) |
| BE (1) | BE824900A (en) |
| CA (1) | CA1048526A (en) |
| CH (1) | CH614933A5 (en) |
| CS (3) | CS185700B2 (en) |
| DD (1) | DD119222A5 (en) |
| DE (1) | DE2500249A1 (en) |
| DK (1) | DK137122B (en) |
| FI (1) | FI750053A (en) |
| FR (1) | FR2258850A1 (en) |
| GB (1) | GB1495422A (en) |
| HK (1) | HK66980A (en) |
| HU (1) | HU168520B (en) |
| IE (1) | IE41131B1 (en) |
| LU (1) | LU71746A1 (en) |
| MY (1) | MY8100207A (en) |
| NL (1) | NL7501044A (en) |
| NO (1) | NO750098L (en) |
| SE (1) | SE419754B (en) |
| SU (3) | SU550977A3 (en) |
| ZA (1) | ZA748195B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0330180U (en) * | 1989-07-31 | 1991-03-25 |
-
1974
- 1974-01-29 SE SE7401096A patent/SE419754B/en unknown
- 1974-12-23 ZA ZA00748195A patent/ZA748195B/en unknown
-
1975
- 1975-01-04 DE DE19752500249 patent/DE2500249A1/en not_active Ceased
- 1975-01-09 FI FI750053A patent/FI750053A/fi not_active Application Discontinuation
- 1975-01-14 NO NO750098A patent/NO750098L/no unknown
- 1975-01-24 CH CH88275A patent/CH614933A5/en not_active IP Right Cessation
- 1975-01-27 DK DK24375AA patent/DK137122B/en unknown
- 1975-01-27 DD DD183835A patent/DD119222A5/xx unknown
- 1975-01-27 SU SU2100968A patent/SU550977A3/en active
- 1975-01-27 HU HUHE674A patent/HU168520B/hu unknown
- 1975-01-28 AT AT61675A patent/AT336037B/en not_active IP Right Cessation
- 1975-01-28 GB GB3684/75A patent/GB1495422A/en not_active Expired
- 1975-01-28 IE IE168/75A patent/IE41131B1/en unknown
- 1975-01-28 LU LU71746*A patent/LU71746A1/xx unknown
- 1975-01-28 CA CA75218830A patent/CA1048526A/en not_active Expired
- 1975-01-28 FR FR7502647A patent/FR2258850A1/en active Granted
- 1975-01-29 CS CS7700001525A patent/CS185700B2/en unknown
- 1975-01-29 CS CS7700001524A patent/CS185699B2/en unknown
- 1975-01-29 NL NL7501044A patent/NL7501044A/en not_active Application Discontinuation
- 1975-01-29 BE BE152806A patent/BE824900A/en unknown
- 1975-01-29 JP JP50012264A patent/JPS50106930A/ja active Pending
- 1975-01-29 CS CS7500000590A patent/CS185673B2/en unknown
- 1975-12-15 SU SU7502198508A patent/SU584761A3/en active
- 1975-12-15 SU SU752198004A patent/SU622395A3/en active
-
1980
- 1980-11-27 HK HK669/80A patent/HK66980A/en unknown
-
1981
- 1981-12-30 MY MY207/81A patent/MY8100207A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SU622395A3 (en) | 1978-08-30 |
| DK137122B (en) | 1978-01-23 |
| SU584761A3 (en) | 1977-12-15 |
| CS185700B2 (en) | 1978-10-31 |
| JPS50106930A (en) | 1975-08-22 |
| DK24375A (en) | 1975-10-06 |
| AT336037B (en) | 1977-04-12 |
| CS185673B2 (en) | 1978-10-31 |
| LU71746A1 (en) | 1975-12-09 |
| BE824900A (en) | 1975-07-29 |
| DE2500249A1 (en) | 1975-07-31 |
| ATA61675A (en) | 1976-08-15 |
| ZA748195B (en) | 1976-01-28 |
| HU168520B (en) | 1976-05-28 |
| SE7401096L (en) | 1975-07-30 |
| MY8100207A (en) | 1981-12-31 |
| SU550977A3 (en) | 1977-03-15 |
| DD119222A5 (en) | 1976-04-12 |
| IE41131B1 (en) | 1979-10-24 |
| FR2258850A1 (en) | 1975-08-22 |
| HK66980A (en) | 1980-12-05 |
| GB1495422A (en) | 1977-12-21 |
| CH614933A5 (en) | 1979-12-28 |
| FI750053A (en) | 1975-07-30 |
| SE419754B (en) | 1981-08-24 |
| DK137122C (en) | 1978-06-26 |
| NL7501044A (en) | 1975-07-31 |
| CA1048526A (en) | 1979-02-13 |
| NO750098L (en) | 1975-08-25 |
| FR2258850B1 (en) | 1980-02-08 |
| CS185699B2 (en) | 1978-10-31 |
| AU7764675A (en) | 1976-07-29 |
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