IE39101B1 - Benzo (ij) quinolizines - Google Patents
Benzo (ij) quinolizinesInfo
- Publication number
- IE39101B1 IE39101B1 IE649/74A IE64974A IE39101B1 IE 39101 B1 IE39101 B1 IE 39101B1 IE 649/74 A IE649/74 A IE 649/74A IE 64974 A IE64974 A IE 64974A IE 39101 B1 IE39101 B1 IE 39101B1
- Authority
- IE
- Ireland
- Prior art keywords
- benzo
- quinolizine
- dihydro
- oxo
- carboxylic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
- C07D215/06—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1627973A GB1433151A (en) | 1973-04-05 | 1973-04-05 | Benzo-ij-quinolizines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE39101L IE39101L (en) | 1974-10-05 |
| IE39101B1 true IE39101B1 (en) | 1978-08-02 |
Family
ID=10074459
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE649/74A IE39101B1 (en) | 1973-04-05 | 1974-03-25 | Benzo (ij) quinolizines |
Country Status (14)
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4051247A (en) * | 1975-04-14 | 1977-09-27 | Riker Laboratories, Inc. | Method of using 7-hydroxy-benzo[ij]quinolizine-2-carboxylic acid derivatives |
| AT377986B (de) * | 1978-08-31 | 1985-05-28 | Otsuka Pharma Co Ltd | Verfahren zur herstellung von neuen piperazinylbenzoheterozyklischen verbindungen und ihren pharmazeutisch annehmbaren salzen |
| JPS5540616A (en) * | 1978-09-14 | 1980-03-22 | Otsuka Pharmaceut Co Ltd | Preparation of benzo-hetero-compound |
| AT377987B (de) * | 1979-04-11 | 1985-05-28 | Otsuka Pharma Co Ltd | Verfahren zur herstellung von neuen piperazinylbenzoheterozyklischen verbindungen und ihren pharmazeutisch annehmbaren salzen |
| US4400386A (en) * | 1981-11-06 | 1983-08-23 | Riker Laboratories, Inc. | Antimicrobial derivatives of 8-amino and 8-aminomethyl benzo(ij)quinolizine |
| US4472407A (en) * | 1983-03-17 | 1984-09-18 | Riker Laboratories, Inc. | Antimicrobial 8-alkoxy-6,7-dihydro-5-methyl-9-fluoro-1-oxo-1H,5H-benzo[ij]qu |
| US4650804A (en) * | 1984-03-30 | 1987-03-17 | Fujisawa Pharmaceutical Co., Ltd. | Quinolizinone compounds and pharmaceutical composition comprising the same, useful as anti-ulcerative and anti-allergic agents |
| CA1266484A (en) * | 1984-12-14 | 1990-03-06 | Ronald Edward Mac Leay | Tert-octylhydrazine, its salts and derivatives |
| DE3519926A1 (de) * | 1985-06-04 | 1986-12-04 | Bayer Ag | Indolinderivate, verfahren zu ihrer herstellung und diese indolinderivate enthaltende kosmetische lichtschutzmittel |
| JP2000505451A (ja) * | 1996-02-21 | 2000-05-09 | ダーウィン・ディスカバリー・リミテッド | キノロン類およびこれらの治療的使用 |
| US5792774A (en) * | 1996-02-21 | 1998-08-11 | Chiroscience Limited | Quinolones and their therapeutic use |
| EP0882046A1 (en) * | 1996-02-21 | 1998-12-09 | Darwin Discovery Limited | Quinolones and their therapeutic use |
| US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
| RU2525115C2 (ru) * | 2004-06-24 | 2014-08-10 | Вертекс Фармасьютикалз Инкорпорейтед | Способ модуляции транспортеров атф-связывающей кассеты |
| EP2502913A3 (en) * | 2004-06-24 | 2013-11-27 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
| CN101006076B (zh) * | 2004-06-24 | 2010-09-29 | 沃泰克斯药物股份有限公司 | Atp-结合弹夹转运蛋白的调控剂 |
| US8354427B2 (en) | 2004-06-24 | 2013-01-15 | Vertex Pharmaceutical Incorporated | Modulators of ATP-binding cassette transporters |
| DK3219705T3 (da) | 2005-12-28 | 2020-04-14 | Vertex Pharma | Farmaceutiske sammensætninger af den amorfe form af n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinolin-3-carboxamid |
| PT2408750E (pt) | 2009-03-20 | 2015-10-15 | Vertex Pharma | Processo para a produção de modeladores do regulador de condutância transmembranar da fibrose cística |
| US8802700B2 (en) | 2010-12-10 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-Binding Cassette transporters |
| EP2819670A1 (en) | 2012-02-27 | 2015-01-07 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administration thereof |
| RU2749213C2 (ru) | 2014-10-07 | 2021-06-07 | Вертекс Фармасьютикалз Инкорпорейтед | Сокристаллы модуляторов регулятора трансмембранной проводимости при кистозном фиброзе |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3728350A (en) * | 1967-07-17 | 1973-04-17 | Lilly Co Eli | 1-(2-carboxyphenyl)-5,7-dimethoxy-3,4-dihydrocarbostyril intermediates for acronycis |
| US3793328A (en) * | 1969-11-03 | 1974-02-19 | Upjohn Co | 8benzoyl 1,2,3,4 tetrahydroquinoline |
| BE789822A (fr) * | 1971-10-08 | 1973-04-06 | Allen & Hanburys Ltd | Nouveaux composes heterocycliques |
| BE793524A (fr) * | 1971-12-30 | 1973-06-29 | Riker Laboratories Inc | Acides benzoquinolizine-carboxyliques et leurs derives |
-
1973
- 1973-04-05 GB GB1627973A patent/GB1433151A/en not_active Expired
-
1974
- 1974-03-21 ZA ZA00741860A patent/ZA741860B/xx unknown
- 1974-03-25 IE IE649/74A patent/IE39101B1/xx unknown
- 1974-03-27 US US455071A patent/US3917608A/en not_active Expired - Lifetime
- 1974-03-27 AU AU67200/74A patent/AU6720074A/en not_active Expired
- 1974-04-01 DE DE2415763A patent/DE2415763A1/de active Pending
- 1974-04-01 LU LU69756A patent/LU69756A1/xx unknown
- 1974-04-01 BE BE142731A patent/BE813158A/xx unknown
- 1974-04-02 CH CH462974A patent/CH602722A5/xx not_active IP Right Cessation
- 1974-04-03 AT AT277074A patent/AT330180B/de not_active IP Right Cessation
- 1974-04-03 FR FR7411776A patent/FR2230355B1/fr not_active Expired
- 1974-04-05 NL NL7404719A patent/NL7404719A/xx not_active Application Discontinuation
- 1974-04-05 CA CA197,107A patent/CA1015758A/en not_active Expired
- 1974-04-05 JP JP49039368A patent/JPS5024296A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ZA741860B (en) | 1975-02-26 |
| BE813158A (fr) | 1974-10-01 |
| GB1433151A (en) | 1976-04-22 |
| IE39101L (en) | 1974-10-05 |
| US3917608A (en) | 1975-11-04 |
| FR2230355B1 (US07993877-20110809-P00003.png) | 1977-05-06 |
| JPS5024296A (US07993877-20110809-P00003.png) | 1975-03-15 |
| LU69756A1 (US07993877-20110809-P00003.png) | 1975-06-16 |
| ATA277074A (de) | 1975-09-15 |
| DE2415763A1 (de) | 1974-10-17 |
| FR2230355A1 (US07993877-20110809-P00003.png) | 1974-12-20 |
| AU6720074A (en) | 1975-10-02 |
| CA1015758A (en) | 1977-08-16 |
| AU474838B2 (US07993877-20110809-P00003.png) | 1976-08-05 |
| NL7404719A (US07993877-20110809-P00003.png) | 1974-10-08 |
| CH602722A5 (US07993877-20110809-P00003.png) | 1978-07-31 |
| AT330180B (de) | 1976-06-25 |
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