IE38780L - Metabolite a-27106 - Google Patents
Metabolite a-27106Info
- Publication number
- IE38780L IE38780L IE740129A IE12974A IE38780L IE 38780 L IE38780 L IE 38780L IE 740129 A IE740129 A IE 740129A IE 12974 A IE12974 A IE 12974A IE 38780 L IE38780 L IE 38780L
- Authority
- IE
- Ireland
- Prior art keywords
- metabolite
- feed
- monensin
- carbon
- molecular weight
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Alternative & Traditional Medicine (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Fodder In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Feed For Specific Animals (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Compounds Of Unknown Constitution (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
1457796 Metabolite A-27106 ELI LILLY & CO 30 Jan 1974 [1 Feb 1973] 04414/74 Headings C2A and C2C The invention relates to Metabolite A-27106 and the acid, ammonium, lithium, potassium, rubidium or cesium forms thereof. The metabolite is a white crystalline solid with (a) a molecular weight of 854, as determined by mass spectrometry; (b) an elemental composition of 58À78% carbon, 8À51% hydrogen, 27À85% oxygen and 3À63% sodium; (c) an empirical formula of C 42 H 71 O 16 Na; (d) an infra-red absorption spectrum in chloroform as shown in the accompanying drawing; (e) a mass spectrum having a molecular-ion peak at m./e. 854À44630 and characteristic peaks at m./e. 836À44129, 779À44690, 761À44740; and (f) an Rf value of 0À49 on silica gel thin layer chromatography in benzene-methanol (7 : 3); and the acid form is a white solid having a molecular weight of 832 and a titratable group with a pKa value of 7À2. The following structure is proposed for Metabolite A-27106. Metabolite A-27106 is prepared by cultivating Streptomyces candidus NRRL 5449 in a culture medium containing assimilable sources of carbon, nitrogen and inorganic salts under submerged aerobic conditions in the presence of glucose and monensin until monensin is converted into metabolite A-27106. The metabolite may be mixed with a physiologically-acceptable carrier, e.g. poultry feed, and administered to poultry for preventing or treating coccidiosis therein. The metabolite may also be mixed with ruminant feed for increasing the efficiency of feed utilization of ruminant animals.
[GB1457796A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32858673A | 1973-02-01 | 1973-02-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE38780L true IE38780L (en) | 1974-08-01 |
| IE38780B1 IE38780B1 (en) | 1978-05-24 |
Family
ID=23281582
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE129/74A IE38780B1 (en) | 1973-02-01 | 1974-01-22 | Metabolite a-27106 and process for its preparation and us |
Country Status (27)
| Country | Link |
|---|---|
| JP (2) | JPS5730477B2 (en) |
| AR (1) | AR206509A1 (en) |
| AT (1) | AT328083B (en) |
| BE (1) | BE810416A (en) |
| BG (1) | BG26953A3 (en) |
| CA (1) | CA1016483A (en) |
| CH (1) | CH589140A5 (en) |
| CS (1) | CS193481B2 (en) |
| DD (1) | DD112441A5 (en) |
| DE (1) | DE2404958C2 (en) |
| DK (1) | DK143036C (en) |
| EG (1) | EG11287A (en) |
| ES (1) | ES422834A1 (en) |
| FI (1) | FI52993C (en) |
| FR (1) | FR2215943B1 (en) |
| GB (1) | GB1457796A (en) |
| HU (1) | HU167276B (en) |
| IE (1) | IE38780B1 (en) |
| IL (1) | IL44065A (en) |
| IN (1) | IN139462B (en) |
| NL (1) | NL181367C (en) |
| NO (1) | NO139788C (en) |
| PH (1) | PH12449A (en) |
| SE (1) | SE401930B (en) |
| SU (1) | SU539538A3 (en) |
| YU (1) | YU36990B (en) |
| ZA (1) | ZA74464B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6384471U (en) * | 1986-11-21 | 1988-06-02 | ||
| JPH0532866Y2 (en) * | 1987-10-27 | 1993-08-23 | ||
| JPH0483920U (en) * | 1990-11-30 | 1992-07-21 | ||
| JPH0512236U (en) * | 1991-07-26 | 1993-02-19 | 東京ラヂエーター製造株式会社 | Fuel tank backflow prevention structure |
-
1974
- 1974-01-01 AR AR252171A patent/AR206509A1/en active
- 1974-01-22 ZA ZA00740464A patent/ZA74464B/en unknown
- 1974-01-22 IL IL44065A patent/IL44065A/en unknown
- 1974-01-22 IE IE129/74A patent/IE38780B1/en unknown
- 1974-01-22 CA CA190,655A patent/CA1016483A/en not_active Expired
- 1974-01-24 PH PH15441A patent/PH12449A/en unknown
- 1974-01-25 YU YU0190/74A patent/YU36990B/en unknown
- 1974-01-29 IN IN191/CAL/74A patent/IN139462B/en unknown
- 1974-01-30 NO NO740292A patent/NO139788C/en unknown
- 1974-01-30 GB GB441474A patent/GB1457796A/en not_active Expired
- 1974-01-30 NL NLAANVRAGE7401311,A patent/NL181367C/en not_active IP Right Cessation
- 1974-01-31 BE BE1005684A patent/BE810416A/en not_active IP Right Cessation
- 1974-01-31 AT AT76874*#A patent/AT328083B/en not_active IP Right Cessation
- 1974-01-31 DD DD176301A patent/DD112441A5/xx unknown
- 1974-01-31 DK DK51474A patent/DK143036C/en not_active IP Right Cessation
- 1974-01-31 HU HUEI523A patent/HU167276B/hu not_active IP Right Cessation
- 1974-01-31 ES ES422834A patent/ES422834A1/en not_active Expired
- 1974-01-31 SE SE7401314A patent/SE401930B/en not_active IP Right Cessation
- 1974-02-01 BG BG7425678A patent/BG26953A3/xx unknown
- 1974-02-01 CH CH143874A patent/CH589140A5/xx not_active IP Right Cessation
- 1974-02-01 DE DE2404958A patent/DE2404958C2/en not_active Expired
- 1974-02-01 SU SU2002131A patent/SU539538A3/en active
- 1974-02-01 JP JP1403874A patent/JPS5730477B2/ja not_active Expired
- 1974-02-01 FI FI283/74A patent/FI52993C/fi active
- 1974-02-01 FR FR7403437A patent/FR2215943B1/fr not_active Expired
- 1974-02-01 CS CS74699A patent/CS193481B2/en unknown
- 1974-02-02 EG EG29/74A patent/EG11287A/en active
-
1981
- 1981-10-20 JP JP56168525A patent/JPS6026374B2/en not_active Expired
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UA8335A1 (en) | The method for the fermentation of microorganisms of alkaligenes entrophus for the obtainment of the cells, containing poly-beta-oxybutyric acid | |
| IE38780L (en) | Metabolite a-27106 | |
| ES8305044A1 (en) | Process for preparing optically pure D- or L-lactic acid. | |
| GB1500965A (en) | Cyclic ether antibiotics | |
| IE791403L (en) | Streptomyces antibiotic | |
| JPS575692A (en) | Production of l-arginine through fermentation process | |
| JPS5635985A (en) | Stabilization of glutamic acid dehydrogenase | |
| PT72825B (en) | Process for the preparation of an injectable oxytetracycline composition | |
| GB1388878A (en) | Antibiotics process for their production and use in ruminant feed | |
| IE45349L (en) | Antibiotic bl580 delta | |
| GB1330900A (en) | Antibiotic thiopeptin compound and the preparation thereof | |
| GB1500846A (en) | Antibiotic a process for its preparation and its use as a medicament | |
| JPS5272886A (en) | Preparation of cephalosporin compound | |
| GB1387769A (en) | Butenoic acid derivatives and a process for the manufacture thereof | |
| JPS5396379A (en) | Peocess for producing microbial cells | |
| JPS575695A (en) | Production of l-histidine through fermentation process | |
| JPS5217471A (en) | Process for preparation of 4- carboxamide-5-cyano-2-imidazolone | |
| GB1244717A (en) | Fermentative production of l-lysine | |
| JPS5375386A (en) | Preparation of l-isoleucine | |
| IE38136B1 (en) | Antibiotic bm123 and production thereof | |
| KR830002034A (en) | Istamycin and its preparation | |
| JPS575691A (en) | Production of l-valine through fermentation process | |
| JPS5768793A (en) | Preparation of l-threonine by fermentation | |
| GB817729A (en) | A new antibiotic p.a. 371 | |
| JPS5271448A (en) | Synthesis of 2-crotonyloxymethyl-(4r,5r,6r)-4,5,6-trihydroxy-cyclohex- 2-enone |