IE38312B1 - 17-esters of 17,21-dihydroxy-20-oxo-steroids - Google Patents

17-esters of 17,21-dihydroxy-20-oxo-steroids

Info

Publication number
IE38312B1
IE38312B1 IE1382/73A IE138273A IE38312B1 IE 38312 B1 IE38312 B1 IE 38312B1 IE 1382/73 A IE1382/73 A IE 1382/73A IE 138273 A IE138273 A IE 138273A IE 38312 B1 IE38312 B1 IE 38312B1
Authority
IE
Ireland
Prior art keywords
prepared
steroids
dihydroxy
ester
betamethasone
Prior art date
Application number
IE1382/73A
Other languages
English (en)
Other versions
IE38312L (en
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of IE38312L publication Critical patent/IE38312L/xx
Publication of IE38312B1 publication Critical patent/IE38312B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/005—Compounds containing elements of Groups 1 or 11 of the Periodic Table without C-Metal linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/08—Copper compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Steroid Compounds (AREA)
IE1382/73A 1972-08-11 1973-08-10 17-esters of 17,21-dihydroxy-20-oxo-steroids IE38312B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3765572A GB1440063A (en) 1972-08-11 1972-08-11 17alpha-esters of 17alpha,21-dihydroxy-20-oxo-steroids

Publications (2)

Publication Number Publication Date
IE38312L IE38312L (en) 1974-02-11
IE38312B1 true IE38312B1 (en) 1978-02-15

Family

ID=10398029

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1382/73A IE38312B1 (en) 1972-08-11 1973-08-10 17-esters of 17,21-dihydroxy-20-oxo-steroids

Country Status (16)

Country Link
US (1) US3891631A (en, 2012)
JP (1) JPS5752359B2 (en, 2012)
BE (1) BE803461A (en, 2012)
CA (1) CA1027109A (en, 2012)
CH (1) CH590884A5 (en, 2012)
DE (1) DE2340591A1 (en, 2012)
DK (1) DK135998B (en, 2012)
ES (1) ES417738A1 (en, 2012)
FR (1) FR2205508B1 (en, 2012)
GB (1) GB1440063A (en, 2012)
IE (1) IE38312B1 (en, 2012)
IL (1) IL42942A (en, 2012)
LU (1) LU68212A1 (en, 2012)
NL (1) NL7311072A (en, 2012)
SE (1) SE387951B (en, 2012)
ZA (2) ZA735452B (en, 2012)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1516095A (en) * 1974-07-31 1978-06-28 Glaxo Lab Ltd 17,21-diesters of 17alpha,21-dihydroxy-steroids of the pregnane series
GB1593978A (en) * 1976-12-31 1981-07-22 Lark Spa Anti-inflammatory steroids
US4086254A (en) * 1977-04-13 1978-04-25 The Upjohn Company Photocleavable steroids
DE2735110A1 (de) * 1977-08-04 1979-02-15 Hoechst Ag Corticoid-17-alkylcarbonate und verfahren zu ihrer herstellung
DE2759135A1 (de) * 1977-12-30 1979-07-19 Lark Spa Neue steroidverbindungen und deren herstellung und verwendung
DE2817988A1 (de) * 1978-04-25 1979-11-08 Hoechst Ag Corticoid 17-alkylcarbonate und verfahren zu deren herstellung
DE3133082A1 (de) 1981-08-18 1983-03-10 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue hydrocortison-derivate, ihre herstellung und verwendung
AU558725B2 (en) * 1983-09-07 1987-02-05 Mitsubishi Kasei Corporation Corticoid derivatives
DE3637806A1 (de) * 1986-11-06 1988-05-19 Hoechst Ag Verfahren zur herstellung von prednisolon-17-ethylcarbonat durch umlagerung von prednisolon-21-ethylcarbonat
FR2683530B1 (fr) * 1991-11-08 1994-01-21 Roussel Uclaf Nouveau procede de preparation de derives 20-oxo 17 alpha, 21-dihydroxyles du pregnane et nouveaux intermediaires.
US6777399B2 (en) * 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
ATE380194T1 (de) * 2000-08-05 2007-12-15 Glaxo Group Ltd 6.alpha.,9.alpha.-difluoro-17.alpha.-(2-
US6759398B2 (en) * 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
US6858596B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
GB0019172D0 (en) * 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
DE60229372D1 (de) * 2001-04-30 2008-11-27 Glaxo Group Ltd Antiphlogistische 7.beta.-carbothioate esterderivate von androstan mit einer 17.alpha.-zyklischen estergruppe
WO2003048181A1 (en) * 2001-12-01 2003-06-12 Glaxo Group Limited 17.alpha. -cyclic esters of 16-methylpregnan-3,20-dione as anti-inflammatory agents
US20050175545A1 (en) * 2002-02-04 2005-08-11 Keith Biggadike Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) * 2002-02-05 2002-03-20 Glaxo Wellcome Mfg Pte Ltd Formulation containing novel anti-inflammatory androstane derivative
GB2389530B (en) * 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
GB0615108D0 (en) * 2006-07-28 2006-09-06 Glaxo Group Ltd Novel formulations
CN103536599A (zh) 2008-05-28 2014-01-29 雷沃根生物医药有限公司 用于治疗疾病的NF-κB的非激素甾体调节剂
EP2556083A4 (en) 2010-04-05 2013-12-04 Validus Biopharma Inc NONHORMONAL STEROID MODULATORS OF NF-KAPPA-B FOR DISEASE TREATMENT
WO2017004205A1 (en) 2015-06-29 2017-01-05 Reveragen Biopharma, Inc. NON-HORMONAL STEROID MODULATORS OF NF-κB FOR TREATMENT OF DISEASE
US11382922B2 (en) 2019-03-07 2022-07-12 Reveragen Biopharma, Inc. Aqueous oral pharmaceutical suspension compositions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3255218A (en) * 1962-03-28 1966-06-07 Schering Corp 17(20)-enol-21-aldehydes of the pregnane series
US3780177A (en) * 1967-06-16 1973-12-18 Warner Lambert Co 17-butyrate,21-ester derivatives of 6alpha,9alpha-difluoroprednisolone,compositions and use
IT1034011B (it) * 1969-06-26 1979-09-10 Vister Vismara Terapeutici S P Processo per la prapratzione di 17 monoesteri di 17 a 21 diossisteroidi per idrolisi die corpispondenti 17 21 ortoesteri ciclici a ph control lato

Also Published As

Publication number Publication date
CH590884A5 (en, 2012) 1977-08-31
NL7311072A (en, 2012) 1974-02-13
CA1027109A (en) 1978-02-28
IE38312L (en) 1974-02-11
JPS4985062A (en, 2012) 1974-08-15
DK135998C (en, 2012) 1977-12-27
AU5914373A (en) 1975-02-13
IL42942A (en) 1977-05-31
BE803461A (fr) 1974-02-11
ES417738A1 (es) 1976-06-16
ZA735453B (en) 1974-10-30
LU68212A1 (en, 2012) 1973-10-16
IL42942A0 (en) 1973-11-28
DE2340591A1 (de) 1974-03-07
US3891631A (en) 1975-06-24
DK135998B (da) 1977-07-25
SE387951B (sv) 1976-09-20
JPS5752359B2 (en, 2012) 1982-11-06
FR2205508B1 (en, 2012) 1978-09-15
FR2205508A1 (en, 2012) 1974-05-31
GB1440063A (en) 1976-06-23
ZA735452B (en) 1974-07-31

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