IE38298B1 - Parenteral benzodiazepine compositions - Google Patents

Parenteral benzodiazepine compositions

Info

Publication number
IE38298B1
IE38298B1 IE42/73A IE4273A IE38298B1 IE 38298 B1 IE38298 B1 IE 38298B1 IE 42/73 A IE42/73 A IE 42/73A IE 4273 A IE4273 A IE 4273A IE 38298 B1 IE38298 B1 IE 38298B1
Authority
IE
Ireland
Prior art keywords
total volume
benzodiazepine
parenteral
jan
solvent
Prior art date
Application number
IE42/73A
Other versions
IE38298L (en
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of IE38298L publication Critical patent/IE38298L/en
Publication of IE38298B1 publication Critical patent/IE38298B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1345510 Benzodiazepine compositions AMERICAN HOME PRODUCTS CORP 11 Jan 1973 [21 Jan 1972] 1502/72 Heading A5B A parenterally acceptable pharmaceutical composition comprises (a) 10-65% of polyethylene glycol based on the total volume of solvent, (b) 35-90% of propylene glycol based on the total volume of solvent, (c) optionally benzyl alcohol and (d) for each ml. total volume of (a), (b) and (c) 1-15 mg. of a benzodiazepine of formula wherein R<SP>1</SP> and R<SP>2</SP> are H or CH 3 and R 3 is H or Cl. [GB1345510A]
IE42/73A 1972-01-21 1973-01-11 Parenteral benzodiazepine compositions IE38298B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21986772A 1972-01-21 1972-01-21

Publications (2)

Publication Number Publication Date
IE38298L IE38298L (en) 1973-07-21
IE38298B1 true IE38298B1 (en) 1978-02-15

Family

ID=22821092

Family Applications (1)

Application Number Title Priority Date Filing Date
IE42/73A IE38298B1 (en) 1972-01-21 1973-01-11 Parenteral benzodiazepine compositions

Country Status (8)

Country Link
AU (1) AU461715B2 (en)
BE (1) BE794224A (en)
DE (1) DE2302659C2 (en)
FR (1) FR2181679B1 (en)
GB (1) GB1345510A (en)
IE (1) IE38298B1 (en)
NL (1) NL7300694A (en)
ZA (1) ZA729004B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1202370B (en) * 1976-07-12 1989-02-09 Hoffmann La Roche INJECTABLE SOLUTIONS IN WHICH THE EMOLITHIC LIFE OF NATURAL MICELLES TRAINING AGENTS IS AVOIDED BY THE ADDITION OF LIPOIDS AND RELATED PRODUCTS
DE3446873A1 (en) * 1984-12-21 1986-07-10 Merckle Gmbh LIQUID DICLOFENAC PREPARATIONS
GB2185887B (en) * 1987-02-18 1989-12-06 Farmitalia Carlo Erba Ltd Temazepam composition
US6780885B1 (en) * 2000-01-14 2004-08-24 Idexx Laboratories, Inc. Formulations and methods for administration of pharmacologically or biologically active compounds
US7851419B2 (en) * 2005-09-12 2010-12-14 Nawaz Ahmad Substantially anhydrous sprayable personal lubricant
JP6080312B2 (en) 2011-04-28 2017-02-15 プラットフォーム ブライトワークス トゥー， リミテッド Improved parenteral formulations of lipophilic pharmaceutical agents and methods for preparing and using the same

Also Published As

Publication number Publication date
AU461715B2 (en) 1975-05-19
NL7300694A (en) 1973-07-24
FR2181679B1 (en) 1981-01-09
GB1345510A (en) 1974-01-30
DE2302659C2 (en) 1986-04-03
FR2181679A1 (en) 1973-12-07
DE2302659A1 (en) 1973-07-26
IE38298L (en) 1973-07-21
AU5024072A (en) 1974-06-20
BE794224A (en) 1973-07-18
ZA729004B (en) 1974-08-28

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