IE38151L - Controlled residence time medicaments - Google Patents

Controlled residence time medicaments

Info

Publication number
IE38151L
IE38151L IE730925A IE92573A IE38151L IE 38151 L IE38151 L IE 38151L IE 730925 A IE730925 A IE 730925A IE 92573 A IE92573 A IE 92573A IE 38151 L IE38151 L IE 38151L
Authority
IE
Ireland
Prior art keywords
core
weight
parts
prepolymer
carbon atoms
Prior art date
Application number
IE730925A
Other versions
IE38151B1 (en
Original Assignee
Purdue Res Fountation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Res Fountation filed Critical Purdue Res Fountation
Publication of IE38151L publication Critical patent/IE38151L/en
Publication of IE38151B1 publication Critical patent/IE38151B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

1428426 Sustained release compositions; diagnostic devices PURDUE RESEARCH FOUNDATION 5 June 1973 [9 June 1972] 26662/73 Heading A5B A sustained release medicament formulation with prolonged gastric residence comprises (a) a medicament core and (b) a pharmaceutically acceptable coating on the core comprising a crosslinked polymeric film which comprises a prepolymer crosslinked with a cross-linking agent at a ratio of 8 parts by weight of prepolymer to 0.15 to 4 parts by weight of crosslinking agent, the prepolymer being a copolymer of (i) 20-90 parts by weight of a substituted or unsubstituted unsaturated dicarboxylic acid or acid anhydride having 1 to 3 carbon atoms between the two carboxylic groups, and (ii) 10-80 parts by weight of an alkene of 2 to 6 carbon atoms, styrene or an alkyl vinyl ether in which the alkyl radical contains 1 to 16 carbon atoms, the polymeric film being waterhydratable, water-permeable and swellable in the presence of gastric fluids. A large number of active ingredients are specified as being suitable for use in the medicament core. The core may also be coated with a binary polymeric film including a pharmaceutically acceptable, substantially water-insoluble polymeric component and a pharmaceutically acceptable polymeric component as defined in (b) above. The medicament core may be replaced by a diagnostic device such as a Heidelberg capsule. [GB1428426A]
IE925/73A 1972-06-09 1973-06-07 Pharmaceutical and diagnostic compositions IE38151B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26124272A 1972-06-09 1972-06-09

Publications (2)

Publication Number Publication Date
IE38151L true IE38151L (en) 1973-12-09
IE38151B1 IE38151B1 (en) 1978-01-04

Family

ID=22992462

Family Applications (1)

Application Number Title Priority Date Filing Date
IE925/73A IE38151B1 (en) 1972-06-09 1973-06-07 Pharmaceutical and diagnostic compositions

Country Status (19)

Country Link
JP (1) JPS4961323A (en)
AU (2) AU5682673A (en)
BE (1) BE800637A (en)
CA (1) CA1040533A (en)
CH (1) CH582002A5 (en)
DD (2) DD112354A5 (en)
DE (1) DE2328580A1 (en)
ES (1) ES415624A3 (en)
FR (1) FR2187290B1 (en)
GB (1) GB1428426A (en)
HU (1) HU167947B (en)
IE (1) IE38151B1 (en)
IL (1) IL42459A (en)
NL (1) NL7307737A (en)
OA (1) OA04931A (en)
PL (1) PL90109B1 (en)
RO (1) RO64146A (en)
SE (1) SE395609B (en)
ZA (1) ZA733897B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207890A (en) 1977-01-04 1980-06-17 Mcneilab, Inc. Drug-dispensing device and method
JPS5911563B2 (en) * 1980-02-27 1984-03-16 日本原子力研究所 Method for manufacturing multilayer sustained release composites
US4518433A (en) * 1982-11-08 1985-05-21 Fmc Corporation Enteric coating for pharmaceutical dosage forms
DE3314003A1 (en) * 1983-04-18 1984-10-18 Boehringer Ingelheim KG, 6507 Ingelheim DIVISIBLE TABLET WITH DELAYED ACTIVE SUBSTANCE RELEASE AND METHOD FOR THE PRODUCTION THEREOF
US4657784A (en) * 1986-03-10 1987-04-14 Ecolab Inc. Process for encapsulating particles with at least two coating layers having different melting points
ES2038669T3 (en) * 1986-09-18 1993-08-01 London School Of Pharmacy Innovations Ltd PHARMACEUTICAL FORMULATION.
US4837030A (en) * 1987-10-06 1989-06-06 American Cyanamid Company Novel controlled release formulations of tetracycline compounds
AU614328B2 (en) * 1988-02-01 1991-08-29 Mayne Pharma International Pty Ltd Tetracycline dosage form
EP0327295A3 (en) * 1988-02-01 1989-09-06 F.H. FAULDING & CO. LTD. Tetracycline dosage form
US5007790A (en) * 1989-04-11 1991-04-16 Depomed Systems, Inc. Sustained-release oral drug dosage form
JP2003521507A (en) 2000-02-04 2003-07-15 ディポメド,インコーポレイティド Shell-core dosage form approaching zero order drug release
US20130143867A1 (en) 2011-12-02 2013-06-06 Sychroneuron Inc. Acamprosate formulations, methods of using the same, and combinations comprising the same
CN105431144A (en) 2013-06-05 2016-03-23 思康脑侒股份有限公司 Acamprosate formulations, methods of using the same, and combinations comprising the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1586811A (en) * 1966-01-06 1970-03-06
AU454482B2 (en) * 1970-11-05 1974-10-15 Alza Corporation Drug-delivery system

Also Published As

Publication number Publication date
NL7307737A (en) 1973-12-11
FR2187290A1 (en) 1974-01-18
ZA733897B (en) 1975-01-29
SE395609B (en) 1977-08-22
GB1428426A (en) 1976-03-17
IE38151B1 (en) 1978-01-04
PL90109B1 (en) 1977-01-31
ES415624A3 (en) 1976-10-16
HU167947B (en) 1976-01-28
DD109309A5 (en) 1974-11-05
AU5935773A (en) 1975-02-20
BE800637A (en) 1973-12-07
IL42459A (en) 1976-12-31
RO64146A (en) 1978-11-15
CH582002A5 (en) 1976-11-30
IL42459A0 (en) 1973-08-29
CA1040533A (en) 1978-10-17
DD112354A5 (en) 1975-04-12
FR2187290B1 (en) 1977-04-15
AU5682673A (en) 1974-12-12
JPS4961323A (en) 1974-06-14
DE2328580A1 (en) 1974-01-10
OA04931A (en) 1980-10-31

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