IE37560B1 - Heterocyclic spiro compounds and processes for their production - Google Patents
Heterocyclic spiro compounds and processes for their productionInfo
- Publication number
- IE37560B1 IE37560B1 IE644/73A IE64473A IE37560B1 IE 37560 B1 IE37560 B1 IE 37560B1 IE 644/73 A IE644/73 A IE 644/73A IE 64473 A IE64473 A IE 64473A IE 37560 B1 IE37560 B1 IE 37560B1
- Authority
- IE
- Ireland
- Prior art keywords
- spiro
- processes
- production
- norbornane
- piperidines
- Prior art date
Links
- -1 Heterocyclic spiro compounds Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- CRLZNHXUODNFHD-UHFFFAOYSA-N 1'-[2-(2-azaspiro[5.5]undecan-2-yl)ethyl]spiro[bicyclo[2.2.2]octane-3,3'-piperidine];dihydrochloride Chemical compound Cl.Cl.C1CCC2(C3CCC(CC3)C2)CN1CCN(C1)CCCC21CCCCC2 CRLZNHXUODNFHD-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003003 spiro group Chemical group 0.000 abstract 1
- BMPLFLKITZPSEQ-UHFFFAOYSA-N spiro[bicyclo[2.2.1]heptane-3,3'-piperidine];hydrochloride Chemical compound Cl.C1CC2CC1CC21CCCNC1 BMPLFLKITZPSEQ-UHFFFAOYSA-N 0.000 abstract 1
- VRQDPNKOUPEWOC-UHFFFAOYSA-N spiro[bicyclo[2.2.2]octane-3,3'-piperidine] Chemical compound C1CCNCC21C(CC1)CCC1C2 VRQDPNKOUPEWOC-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/96—Spiro-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH661372A CH582143A5 (cg-RX-API-DMAC10.html) | 1972-05-04 | 1972-05-04 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE37560L IE37560L (en) | 1973-11-04 |
| IE37560B1 true IE37560B1 (en) | 1977-08-17 |
Family
ID=4312312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE644/73A IE37560B1 (en) | 1972-05-04 | 1973-04-25 | Heterocyclic spiro compounds and processes for their production |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US3914222A (cg-RX-API-DMAC10.html) |
| JP (1) | JPS4961160A (cg-RX-API-DMAC10.html) |
| AR (3) | AR203267A1 (cg-RX-API-DMAC10.html) |
| AT (1) | AT328446B (cg-RX-API-DMAC10.html) |
| AU (1) | AU5510673A (cg-RX-API-DMAC10.html) |
| BE (1) | BE799023A (cg-RX-API-DMAC10.html) |
| CH (1) | CH582143A5 (cg-RX-API-DMAC10.html) |
| DD (1) | DD107032A5 (cg-RX-API-DMAC10.html) |
| DE (1) | DE2321057A1 (cg-RX-API-DMAC10.html) |
| ES (1) | ES414277A1 (cg-RX-API-DMAC10.html) |
| FR (1) | FR2183204B1 (cg-RX-API-DMAC10.html) |
| GB (1) | GB1428480A (cg-RX-API-DMAC10.html) |
| HU (1) | HU169463B (cg-RX-API-DMAC10.html) |
| IE (1) | IE37560B1 (cg-RX-API-DMAC10.html) |
| IL (1) | IL42104A (cg-RX-API-DMAC10.html) |
| NL (1) | NL7306276A (cg-RX-API-DMAC10.html) |
| PL (2) | PL89236B1 (cg-RX-API-DMAC10.html) |
| SU (4) | SU506292A3 (cg-RX-API-DMAC10.html) |
| ZA (1) | ZA732804B (cg-RX-API-DMAC10.html) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2931805A (en) * | 1958-11-10 | 1960-04-05 | Smith Kline French Lab | Spiro [bicyclo [2. 2. 1] heptane-2, 2'-alkylenimines] |
-
1972
- 1972-05-04 CH CH661372A patent/CH582143A5/xx not_active IP Right Cessation
-
1973
- 1973-04-25 ZA ZA732804A patent/ZA732804B/xx unknown
- 1973-04-25 IE IE644/73A patent/IE37560B1/xx unknown
- 1973-04-25 IL IL42104A patent/IL42104A/en unknown
- 1973-04-26 DE DE2321057A patent/DE2321057A1/de active Pending
- 1973-04-30 GB GB2045473A patent/GB1428480A/en not_active Expired
- 1973-05-02 ES ES414277A patent/ES414277A1/es not_active Expired
- 1973-05-02 US US356545A patent/US3914222A/en not_active Expired - Lifetime
- 1973-05-02 DD DD170569A patent/DD107032A5/xx unknown
- 1973-05-02 JP JP48049647A patent/JPS4961160A/ja active Pending
- 1973-05-02 AU AU55106/73A patent/AU5510673A/en not_active Expired
- 1973-05-03 PL PL1973162293A patent/PL89236B1/pl unknown
- 1973-05-03 FR FR7315859A patent/FR2183204B1/fr not_active Expired
- 1973-05-03 SU SU1921901A patent/SU506292A3/ru active
- 1973-05-03 AT AT390373A patent/AT328446B/de not_active IP Right Cessation
- 1973-05-03 BE BE130678A patent/BE799023A/xx unknown
- 1973-05-03 HU HUCI1369A patent/HU169463B/hu unknown
- 1973-05-03 PL PL1973183139A patent/PL94194B1/pl unknown
- 1973-05-04 NL NL7306276A patent/NL7306276A/xx unknown
- 1973-05-04 AR AR247860A patent/AR203267A1/es active
-
1974
- 1974-01-01 AR AR253541A patent/AR207446A1/es active
- 1974-01-01 AR AR253540A patent/AR207634A1/es active
- 1974-07-12 SU SU2043837A patent/SU514568A3/ru active
- 1974-07-12 SU SU2043836A patent/SU508191A3/ru active
- 1974-07-12 SU SU2043773A patent/SU521841A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| ZA732804B (en) | 1974-04-24 |
| IE37560L (en) | 1973-11-04 |
| IL42104A0 (en) | 1973-07-30 |
| JPS4961160A (cg-RX-API-DMAC10.html) | 1974-06-13 |
| NL7306276A (cg-RX-API-DMAC10.html) | 1973-11-06 |
| SU514568A3 (ru) | 1976-05-15 |
| US3914222A (en) | 1975-10-21 |
| DD107032A5 (cg-RX-API-DMAC10.html) | 1974-07-12 |
| AU5510673A (en) | 1974-11-07 |
| AR207634A1 (es) | 1976-10-22 |
| IL42104A (en) | 1976-12-31 |
| AR203267A1 (es) | 1975-08-29 |
| ES414277A1 (es) | 1976-01-16 |
| ATA390373A (de) | 1975-06-15 |
| FR2183204B1 (cg-RX-API-DMAC10.html) | 1976-05-14 |
| GB1428480A (en) | 1976-03-17 |
| DE2321057A1 (de) | 1973-11-22 |
| SU506292A3 (ru) | 1976-03-05 |
| PL89236B1 (cg-RX-API-DMAC10.html) | 1976-11-30 |
| PL94194B1 (cg-RX-API-DMAC10.html) | 1977-07-30 |
| AR207446A1 (es) | 1976-10-08 |
| SU508191A3 (ru) | 1976-03-25 |
| SU521841A3 (ru) | 1976-07-15 |
| BE799023A (fr) | 1973-11-05 |
| AT328446B (de) | 1976-03-25 |
| CH582143A5 (cg-RX-API-DMAC10.html) | 1976-11-30 |
| FR2183204A1 (cg-RX-API-DMAC10.html) | 1973-12-14 |
| HU169463B (cg-RX-API-DMAC10.html) | 1976-11-28 |
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