IE36050B1 - Ureas thioureas and guanidines - Google Patents

Ureas thioureas and guanidines

Info

Publication number
IE36050B1
IE36050B1 IE136/72A IE13672A IE36050B1 IE 36050 B1 IE36050 B1 IE 36050B1 IE 136/72 A IE136/72 A IE 136/72A IE 13672 A IE13672 A IE 13672A IE 36050 B1 IE36050 B1 IE 36050B1
Authority
IE
Ireland
Prior art keywords
thioureas
guanidines
ureas
ureas thioureas
Prior art date
Application number
IE136/72A
Other languages
English (en)
Other versions
IE36050L (en
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26240626&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IE36050(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to GB635271A priority Critical patent/GB1338169A/en
Priority claimed from GB635271A external-priority patent/GB1338169A/en
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Priority to CA134,517A priority patent/CA949967A/en
Priority to FR7207170A priority patent/FR2128505B1/fr
Priority to CH553575A priority patent/CH578584A5/xx
Priority to CH553475A priority patent/CH578583A5/xx
Priority to CH338172A priority patent/CH576478A5/xx
Priority to DE19722211454 priority patent/DE2211454B2/de
Priority to NL7203145.A priority patent/NL162073C/xx
Priority to DE2265369A priority patent/DE2265369C3/de
Publication of IE36050L publication Critical patent/IE36050L/xx
Priority to US450937A priority patent/US3905984A/en
Priority to US05/450,931 priority patent/US3932427A/en
Priority to US05/450,957 priority patent/US3950333A/en
Priority to US05/451,333 priority patent/US3950353A/en
Priority to JP49147490A priority patent/JPS5243832B2/ja
Priority to JP49147491A priority patent/JPS5243833B2/ja
Priority to US05/586,670 priority patent/US4027026A/en
Priority to US05/626,682 priority patent/US4018928A/en
Priority to US05/637,496 priority patent/US4022797A/en
Priority to US05/637,499 priority patent/US4024271A/en
Priority to US05/637,494 priority patent/US4018931A/en
Priority to US05/638,005 priority patent/US4053473A/en
Priority to US05/667,738 priority patent/US4049672A/en
Publication of IE36050B1 publication Critical patent/IE36050B1/xx
Priority to US05/758,291 priority patent/US4069327A/en
Priority to US05/764,921 priority patent/US4137237A/en
Priority to US05/765,040 priority patent/US4070475A/en
Priority to US05/805,491 priority patent/US4137234A/en
Priority to US05/837,961 priority patent/US4151288A/en
Priority to US05/847,285 priority patent/US4154844A/en
Priority to US05/940,547 priority patent/US4230865A/en
Priority to US05/948,358 priority patent/US4228291A/en
Priority to US06/003,160 priority patent/US4226874A/en
Priority to US06/010,105 priority patent/US4221802A/en
Priority to US06/126,809 priority patent/US4287198A/en
Priority to US06/130,760 priority patent/US4307101A/en
Priority to US06/132,605 priority patent/US4293699A/en
Priority to US06/138,637 priority patent/US4293697A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/32—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/46—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C07D285/135—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Handcart (AREA)
IE136/72A 1971-03-09 1972-02-03 Ureas thioureas and guanidines IE36050B1 (en)

Priority Applications (36)

Application Number Priority Date Filing Date Title
GB635271A GB1338169A (en) 1971-03-09 1971-03-09 Ureas thioureas and guanidines
CA134,517A CA949967A (en) 1971-03-09 1972-02-11 Pharmacologically active compounds
FR7207170A FR2128505B1 (fi) 1971-03-09 1972-03-02
CH338172A CH576478A5 (fi) 1971-03-09 1972-03-08
CH553475A CH578583A5 (fi) 1971-03-09 1972-03-08
CH553575A CH578584A5 (fi) 1971-03-09 1972-03-08
DE19722211454 DE2211454B2 (de) 1971-03-09 1972-03-09 Heterocyclische harnstoff-, thioharnstoff- und guanidinderivate, ihre salze mit saeuren und ihre verwendung als histamin- h tief 2 - receptor-antagonisten
NL7203145.A NL162073C (nl) 1971-03-09 1972-03-09 Werkwijze voor het bereiden van geneesmiddelen met histamine-receptor blokkerende activiteit, aldus ver- kregen gevormde geneesmiddelen, alsmede de bereiding van daarvoor geschikte actieve verbindingen.
DE2265369A DE2265369C3 (de) 1971-03-09 1972-03-09 Heterocyclische Aminoäther und -thioäther und ihre Salze mit Säuren
US450937A US3905984A (en) 1971-03-09 1974-03-13 Pyridyl substituted thioalkyl-and oxyalkyl-thioureas and ureas
US05/450,931 US3932427A (en) 1971-03-09 1974-03-13 Pyridyl substituted aminoalkyl-thioureas and ureas
US05/451,333 US3950353A (en) 1971-03-09 1974-03-14 Pharmacologically active thiourea and urea compounds
US05/450,957 US3950333A (en) 1971-03-09 1974-03-14 Pharmacologically active guanidine compounds
JP49147490A JPS5243832B2 (fi) 1971-03-09 1974-12-20
JP49147491A JPS5243833B2 (fi) 1971-03-09 1974-12-20
US05/586,670 US4027026A (en) 1971-03-09 1975-06-13 Pharmaceutical compositions and methods of inhibiting H-2 histamine receptors with pyridyl substituted thioalkyl- and oxyalkyl-thioureas and ureas
US05/626,682 US4018928A (en) 1971-03-09 1975-10-29 Pyridyl substituted aminoalkyl-thioureas and ureas
US05/637,499 US4024271A (en) 1971-03-09 1975-12-04 Pharmacologically active guanidine compounds
US05/637,494 US4018931A (en) 1971-03-09 1975-12-04 Pharmacologically active thiourea and urea compounds
US05/637,496 US4022797A (en) 1971-03-09 1975-12-04 Certain thiazole, isothiazole, oxazole, and isoxazole compounds
US05/638,005 US4053473A (en) 1971-07-22 1975-12-05 Pharmacologically active thiourea and urea compounds
US05/667,738 US4049672A (en) 1971-03-09 1976-03-17 4-Methyl-5-imidazolylmethylthioethylamine and -S-methylisothiourea
US05/758,291 US4069327A (en) 1971-03-09 1977-01-05 Pharmacologically active thiourea and urea compounds as inhibitors of H-2 histamine receptors
US05/764,921 US4137237A (en) 1971-03-09 1977-02-02 Pharmacologically active guanidine compounds
US05/765,040 US4070475A (en) 1972-02-03 1977-02-02 Pharmacologically active guanidine compounds as H-2 histamine receptor inhibitors
US05/805,491 US4137234A (en) 1971-03-09 1977-06-10 Thiazole, isothiazole, oxazole and isoxazole substituted thiourea and urea compounds
US05/837,961 US4151288A (en) 1971-03-09 1977-09-29 Pharmacologically active thiourea and urea compounds
US05/847,285 US4154844A (en) 1971-03-09 1977-10-31 Pharmacologically active guanidine compounds in compositions and methods of use
US05/940,547 US4230865A (en) 1971-03-09 1978-09-08 Pharmacologically active triazole and thiadiazole thiourea and urea compounds
US05/948,358 US4228291A (en) 1971-03-09 1978-10-04 Pharmacologically active thiadiazole guanidine compounds
US06/003,160 US4226874A (en) 1971-03-09 1979-01-15 Pharmacologically active thiourea and urea compositions and methods of use
US06/010,105 US4221802A (en) 1972-02-03 1979-02-07 Pharmacologically active guanidine compounds for inhibiting H-2 histamine receptors
US06/126,809 US4287198A (en) 1971-03-09 1980-03-03 Pharmacologically active guanidine compounds
US06/130,760 US4307101A (en) 1971-03-09 1980-03-17 Inhibitors of H-2 histamine receptors
US06/132,605 US4293699A (en) 1972-02-03 1980-03-21 Pharmacologically active guanidine compounds
US06/138,637 US4293697A (en) 1971-03-09 1980-04-09 Pharmacologically active thiourea and urea compounds

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB635271A GB1338169A (en) 1971-03-09 1971-03-09 Ureas thioureas and guanidines
GB3433471 1971-07-22

Publications (2)

Publication Number Publication Date
IE36050L IE36050L (en) 1972-09-09
IE36050B1 true IE36050B1 (en) 1976-08-04

Family

ID=26240626

Family Applications (1)

Application Number Title Priority Date Filing Date
IE136/72A IE36050B1 (en) 1971-03-09 1972-02-03 Ureas thioureas and guanidines

Country Status (21)

Country Link
JP (5) JPS5324422B1 (fi)
AR (2) AR197080A1 (fi)
BE (1) BE779775A (fi)
CY (1) CY856A (fi)
DK (1) DK139870B (fi)
EG (1) EG10876A (fi)
ES (1) ES400587A1 (fi)
FI (1) FI60393C (fi)
HK (1) HK55176A (fi)
HU (1) HU164509B (fi)
IE (1) IE36050B1 (fi)
IL (1) IL38821A (fi)
IT (1) IT1041101B (fi)
KE (1) KE2625A (fi)
MY (1) MY7600228A (fi)
NO (1) NO133196C (fi)
PH (2) PH12207A (fi)
SE (3) SE402288B (fi)
SG (1) SG28576G (fi)
SU (1) SU460628A3 (fi)
ZM (1) ZM3672A1 (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1397436A (en) * 1972-09-05 1975-06-11 Smith Kline French Lab Heterocyclic n-cyanoguinidines
US4000296A (en) * 1972-09-05 1976-12-28 Smith Kline & French Laboratories Limited Imidazole alkylguanidine compounds
US4072748A (en) * 1972-09-05 1978-02-07 Smith Kline & French Laboratories Limited Certain guanidine compounds, and their use as inhibitors of histamine activity
GB1398426A (en) * 1972-09-05 1975-06-18 Smith Kline French Lab Heterocyclic substituted guanidines
US4129657A (en) 1975-03-21 1978-12-12 Smith, Kline & French Laboratories Limited Imidazole guanidines and use as inhibitors of histamine activity
IL56265A (en) * 1977-12-28 1982-08-31 Om Lab Sa Process for preparing imidazolyl methylthio guanidine derivatives and a novel intermediate therefor
JPH07107054B2 (ja) * 1987-05-20 1995-11-15 株式会社日本触媒 ４−メチル−５−〔（２−アミノエチル）チオメチル〕イミダゾ−ル二塩酸塩の製法
JP2933739B2 (ja) * 1990-04-09 1999-08-16 明治製菓株式会社 チアゾールまたはイミダゾール誘導体および抗潰瘍剤

Also Published As

Publication number Publication date
JPS5732063B2 (fi) 1982-07-08
IT1041101B (it) 1980-01-10
SE402288B (sv) 1978-06-26
MY7600228A (en) 1976-12-31
HU164509B (fi) 1974-02-28
FI60393C (fi) 1982-01-11
IL38821A0 (en) 1972-10-29
PH12207A (en) 1978-11-29
CY856A (en) 1976-09-10
DK139870C (fi) 1979-10-08
JPS5459275A (en) 1979-05-12
BE779775A (fr) 1972-08-24
SG28576G (en) 1987-04-03
EG10876A (en) 1976-07-31
JPS53119867A (en) 1978-10-19
AR197093A1 (es) 1974-03-15
JPS53119868A (en) 1978-10-19
HK55176A (en) 1976-09-17
ZM3672A1 (en) 1972-10-23
JPS5324422B1 (fi) 1978-07-20
SE410103B (sv) 1979-09-24
NO133196B (fi) 1975-12-15
ES400587A1 (es) 1975-07-16
JPS5811948B2 (ja) 1983-03-05
JPS53119869A (en) 1978-10-19
FI60393B (fi) 1981-09-30
NO133196C (fi) 1976-03-24
AR197080A1 (es) 1974-03-15
JPS5742068B2 (fi) 1982-09-07
SE7610842L (sv) 1976-09-30
DK139870B (da) 1979-05-07
SE7412680L (fi) 1974-10-09
SE430689B (sv) 1983-12-05
SU460628A3 (ru) 1975-02-15
IL38821A (en) 1975-05-22
KE2625A (en) 1976-05-28
PH12247A (en) 1978-12-12
IE36050L (en) 1972-09-09

Similar Documents

Publication Publication Date Title
MY7600028A (en) Ureas, thioureas and guanidines
AR197468A1 (es) Conjunto de pinon y cremallera
PH11618A (en) Ureas,thioureas and guanides
IL38717A0 (en) Brush and its manufacture
IL39376A (en) Nor-prostaglandin e and f analogues
IL38178A0 (en) Thioureas
PH10385A (en) N-(furyl-methyl)-3-oxy-morphinans and salts thereof
ZA717362B (en) Carbamoyl and urea sulfides
IE36050B1 (en) Ureas thioureas and guanidines
GB1385998A (en) Sliding clasp fastener
ZA713832B (en) Thiadiazole ureas
CA1003855B (en) 1-hydrocarbyldithio-3-aryl ureas
GB1403550A (en) 3-carbamoyl-3-hyeroxy-4-halobutyric acid and the preparation thereof
IE35835L (en) Thioureas
IL38161A (en) Substituted phenyl ureas and thioureas and their use as herbicides
IE36176L (en) Strip fastener
IL38057A0 (en) Carbamoyl and urea sulfides
AU460353B2 (en) Unsaturated heterocyclic-substituted thioureas ureas and guanidines
IL40996A0 (en) The preparation of substituted ureas
IL39068A0 (en) Novel thioureas,their preparation and their use as fungicides
IL39343A (en) The preparation of 4-hydroxy-benzodioxoles and 4-benzidioxolyl carbamates
IL33677A0 (en) New substituted ureas and thioureas and process of preparation
CA807661A (en) N-phenyl-n'-tricyclic substituted ureas and thioureas
ZA727252B (en) Sliding clasp fastener
IE36500L (en) Quinazoline